scholarly journals Natural and anthropogenic radioactivity of feedstuffs, mosses and soil in the Belgrade environment, Serbia

2010 ◽  
Vol 62 (2) ◽  
pp. 301-307 ◽  
Author(s):  
Svetlana Grdovic ◽  
Gordana Vitorovic ◽  
Branislava Mitrovic ◽  
V. Andric ◽  
B. Petrujkic ◽  
...  
Keyword(s):  
Natural Radionuclides ◽  
Living Environment ◽  
Spectroscopic Measurement ◽  
Activity Level ◽  
Level Of Activity ◽  
Radio Nuclide ◽  
Nuclide Activity ◽  
High Level ◽  
Range Of Values ◽  
137Cs Contamination

By gamma spectroscopic measurement a content of natural radio-nuclides (40K, 238U, 226Ra, 232Th) and 137Cs was determined in samples of soil, alfalfa, maize and moss on six sites in the surroundings of Belgrade. Natural radionuclides in the soil were at the level characteristic for Serbia, whereas a relatively high level of activity of 137Cs (around 30 Bq kg-1) was determined. On the other hand, in plant samples mostly used as feed (such as alfalfa and maize) the concentration of natural radio-nuclide activity and 137Cs was relatively low, i.e. below the range of detection. The content of natural radio-nuclides in moss was within the standard range of values specific for Serbia. However, the activity level of 137Cs in moss gathered from the wider area around Belgrade, was high, the highest measured level being in the Avala-Zuce area (158-221 Bq kg-1). Our results show that this radio-nuclide is still present in the living environment of Belgrade even 20 years after the Chernobyl disaster, and that moss is a good indicator of living environment 137Cs contamination.

scholarly journals Increased Strength following Achilles Tendon Rupture Repair is Associated with Return to Same Level of Play in Patients with Higher Pre-Injury Level of Activity

2020 ◽  
Vol 5 (4) ◽  
pp. 2473011420S0025
Author(s):  
Russell E. Holzgrefe ◽  
Timothy McCarthy ◽  
Jacob M. Wilson ◽  
Jason T. Bariteau ◽  
Sameh A. Labib
Keyword(s):  
Achilles Tendon ◽  
Achilles Tendon Rupture ◽  
Activity Level ◽  
Return To Play ◽  
Athletic Activity ◽  
Level Of Activity ◽  
Ankle Strength ◽  
High Level ◽  
The Relationship ◽  
Tegner Activity Level

Category: Hindfoot; Sports; Trauma Introduction/Purpose: Rupture of the Achilles tendon is a common injury that requires a lengthy duration of recovery and rehabilitation. Patients of various levels of physical activity, ranging from professional high-impact sports to low-impact recreational activities, can be affected by this injury. Often, one of the most important outcomes from the patient’s perspective is the ability to return to the same pre-injury level of sporting activity after recovery. The objective of the current study is to examine the relationship between global ankle strength and the ability to return to previous level of play following surgical repair of an Achilles tendon tear. Methods: Patients aged 18-50 years old at a minimum 1-year post-op from surgical repair of an isolated Achilles tendon rupture were recruited to return for a study visit. Patients reported both pre-injury and current activity level using the 10-point Tegner Activity Level Scale. Isokinetic strength testing was performed and the Isokinetic Strength Score (ISS) was calculated using maximal effort dorsiflexion and plantarflexion strength at 30o/s, 90o/s, and 240o/s comparing the operative and uninvolved extremity. The primary outcome was the patients’ ability to return to same level of play or within 1 Tegner activity level. Logitistic regression analysis was used to determine the relationship between ISS and return to play. Subgroup analysis was performed on patients participating in high level athletic activity (pre-injury Tegner >= 7) an those participating in only recreational or low level activity (pre-injury Tegner <7). Results: A total of 36 patients (mean 35 years, 72% male) completed the study protocol at a mean 1.8 years post-op (range 1 year to 3.6 years). Logistic regression revealed no association between ISS and return to play in the complete cohort. Subgroup analysis revealed that for 20 patients who had participated in high level competitive athletics prior to injury (Pre-injury Tegner >= 7), for every 16 point increase in ISS, the odds ratio for return to same level of play was 8.3 (p=0.055) and the OR for return to within 1 Tegner level of play was 6.3 (p=0.043). There was no association between ISS and return to previous activity in the 16 patients with lower pre-injury levels of activity. Conclusion: Improved ankle strength was associated with return to previous level of activity only in patients who participate in high level athletic activity. These results suggest that patients with more strenuous athletic activity prior to injury are more dependent on recovery of ankle strength in the post-operative time period in order to return to their previous high level of play. In contrast, regaining strength may be less important for returning to normal activities for less active patients. [Table: see text]

scholarly journals INCREASING THE ABILITY TO UNDERSTAND MATHEMATICS THROUGH DISCOVERY LEARNING MODEL FOR PGMI STUDENTS AT MUHAMMADIYAH UNIVERSITY WEST SUMATERA

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Ridania Ekawati
Keyword(s):  
Creative Thinking ◽  
Mathematics Learning ◽  
Learning Model ◽  
Discovery Learning ◽  
Activity Level ◽  
Moderate Activity ◽  
Quantitative Research Methods ◽  
Level Of Activity ◽  
High Level ◽  
Very High

Problem research students of PGMI UMSB find it difficult to understand Mathematics learning. Students do not play an active role and think creatively, indicated by low participation in learning. The research objective was to improve the ability to understand mathematics learning at PGMI with the Discovery Learning model. Qualitative and quantitative research methods. Types of Classroom Action Research. The research was conducted in 2 cycles for 2 meetings. Data collection by pretest, posttest, observation, and interviews about the implementation of learning before and after using the discovry learning model. The results of the pretest students think quite creatively 45% while students think less creatively 50%, only 5% think very creatively. In the first cycle of the first meeting of learning with the online discovery learning model with the zoom application, it was seen that 12.5% of students had very high activity level, 25% of students had high level of activity, and 62.5% of students had moderate activity. The percentage of creative thinking is 67% and less creative thinking is 25%, 8% of students think very creatively. In the second cycle student activity in learning increased by 17%, the level of activity was very high, 67% of students had high level of activity, and 16% of students had moderate activity. Students who think creatively reach 80% and think very creatively at 20%. The increase in the average value and the percentage of completeness can be indicated that the application of the discovery learning model of PGMI students can understand  mathematics learning.

scholarly journals The risk of venous thromboembolism and physical activity level, especially high level: a systematic review

2021 ◽  
Author(s):  
H. Danin-Mankowitz ◽  
A. Ugarph-Morawski ◽  
F. Braunschweig ◽  
P. Wändell
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Venous Thromboembolism ◽  
Activity Level ◽  
Case Control Studies ◽  
The Third ◽  
Area Of Interest ◽  
High Level ◽  
The Relationship

AbstractVenous thromboembolism (VTE) is the third most common cause of cardiovascular disease. Connection between high level of physical activity (PA) and the onset of VTE is unknown. We searched the literature on the possible association between PA level, especially high levels, and the risk of VTE. A systematic review was carried out to identify relevant articles on the relation between PA level and VTE. The initial search was conducted together with the Karolinska Institutet University Library in February 2018, with follow-up searches after that. In total, 4383 records were found and then screened for exclusion of duplicates and articles outside the area of interest. In total, 16 articles with data on 3 or more levels of PA were included. Of these, 12 were cohort and 4 were case-control studies. Totally 13 studies aimed at investigating VTE cases primarily, while three studies had other primary outcomes. Of the 16 studies, five found a U-shaped association between PA level and VTE risk, although non-significant in three of them. Two articles described an association between a more intense physical activity and a higher risk of VTE, which was significant in one. Nine studies found associations between increasing PA levels and a decreasing VTE risk. Available literature provides diverging results as to the association between high levels of PA and the risk of venous thromboembolism, but with several studies showing an association. Further research is warranted to clarify the relationship between high level PA and VTE.

scholarly journals Spo0A-Dependent Activation of an Extended −10 Region Promoter in Bacillus subtilis

2006 ◽  
Vol 188 (4) ◽  
pp. 1411-1418 ◽  
Author(s):  
Guangnan Chen ◽  
Amrita Kumar ◽  
Travis H. Wyman ◽  
Charles P. Moran
Keyword(s):  
Bacillus Subtilis ◽  
Base Pair ◽  
Promoter Activity ◽  
Mutational Analysis ◽  
Dna Binding Protein ◽  
Base Pairs ◽  
Dnase I Footprinting ◽  
Level Of Activity ◽  
High Level ◽  
Activity Dependent

ABSTRACT At the onset of endospore formation in Bacillus subtilis the DNA-binding protein Spo0A directly activates transcription from promoters of about 40 genes. One of these promoters, Pskf, controls expression of an operon encoding a killing factor that acts on sibling cells. AbrB-mediated repression of Pskf provides one level of security ensuring that this promoter is not activated prematurely. However, Spo0A also appears to activate the promoter directly, since Spo0A is required for Pskf activity in a ΔabrB strain. Here we investigate the mechanism of Pskf activation. DNase I footprinting was used to determine the locations at which Spo0A bound to the promoter, and mutations in these sites were found to significantly reduce promoter activity. The sequence near the −10 region of the promoter was found to be similar to those of extended −10 region promoters, which contain a TRTGn motif. Mutational analysis showed that this extended −10 region, as well as other base pairs in the −10 region, is required for Spo0A-dependent activation of the promoter. We found that a substitution of the consensus base pair for the nonconsensus base pair at position −9 of Pskf produced a promoter that was active constitutively in both ΔabrB and Δspo0A ΔabrB strains. Therefore, the base pair at position −9 of Pskf makes its activity dependent on Spo0A binding, and the extended −10 region motif of the promoter contributes to its high level of activity.

scholarly journals A new assay for nitric oxide reductase reveals two conserved glutamate residues form the entrance to a proton-conducting channel in the bacterial enzyme

2006 ◽  
Vol 401 (1) ◽  
pp. 111-119 ◽  
Author(s):  
Faye H. Thorndycroft ◽  
Gareth Butland ◽  
David J. Richardson ◽  
Nicholas J. Watmough
Keyword(s):  
Nitric Oxide ◽  
Paracoccus Denitrificans ◽  
Nitric Oxide Reductase ◽  
Transmembrane Helices ◽  
Level Of Activity ◽  
Bacterial Enzyme ◽  
Cytoplasmic Membranes ◽  
Membrane Bound ◽  
Proton Movement ◽  
High Level

A specific amperometric assay was developed for the membrane-bound NOR [NO (nitric oxide) reductase] from the model denitrifying bacterium Paracoccus denitrificans using its natural electron donor, pseudoazurin, as a co-substrate. The method allows the rapid and specific assay of NO reduction catalysed by recombinant NOR expressed in the cytoplasmic membranes of Escherichia coli. The effect on enzyme activity of substituting alanine, aspartate or glutamine for two highly conserved glutamate residues, which lie in a periplasmic facing loop between transmembrane helices III and IV in the catalytic subunit of NOR, was determined using this method. Three of the substitutions (E122A, E125A and E125D) lead to an almost complete loss of NOR activity. Some activity is retained when either Glu122 or Glu125 is substituted with a glutamine residue, but only replacement of Glu122 with an aspartate residue retains a high level of activity. These results are interpreted in terms of these residues forming the mouth of a channel that conducts substrate protons to the active site of NOR during turnover. This channel is also likely to be that responsible in the coupling of proton movement to electron transfer during the oxidation of fully reduced NOR with oxygen [U. Flock, N. J. Watmough and P. Ädelroth (2005) Biochemistry 44, 10711–10719].

scholarly journals The Impact of CEOs' Compensations on Cost Stickiness in Industrial Companies Listed on the Amman Stock Exchange

2021 ◽  
Vol 15 (1) ◽  
pp. 152
Author(s):  
Lina Fuad Hussien
Keyword(s):  
Stock Exchange ◽  
Industrial Companies ◽  
Level Of Activity ◽  
Cost Behavior ◽  
Study Population ◽  
The Difference ◽  
High Level ◽  
The Cost ◽  
The Impact ◽  
Cost Stickiness

The purpose of this study is to analyze the asymmetry in cost behavior (cost stickiness) and to identify the impact of CEOs&#39; compensation on the degree of cost stickiness behavior. The study population consists of the public shareholding companies listed on the ASE, which number (56) industrial company. Data were collected from (35) industrial companies for the period (2009 - 2019). To measure the degree of costs stickiness, The Model of Weiss (2010) was used. The Model of Weiss (2010) takes into account the costs and changes in the level of activity (sales) for the last four quarters of the company, Weiss (2010) model constructs the difference in logarithmic ratios of changes in cost. The study found that the CEO&#39;s compensation in Jordanian industrial companies consists of two forms. The companies pay fixed salaries or performance-related bonuses. The study found that the form of compensation that is paid to the CEO affects the behavior of managers. The results indicated that the performance-related rewards are accompanied by a decrease in the level of cost stickiness, and the compensation paid in the form of fixed salaries are accompanied by a high level of cost stickiness. The study recommends that companies should understand the role of the compensation form in administrative decisions, especially with regard to resource modifications, as management motives in relation to resource modifications must be taken into account because of their clear and direct impact on the cost structure of companies.

scholarly journals Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity

2011 ◽  
Vol 65 (4) ◽  
pp. 403-409 ◽  
Author(s):  
Ruzica Nikolic ◽  
Jasmina Jovanovic ◽  
Gordana Kocic ◽  
Tatjana Cvetkovic ◽  
Svetlana Stojanovic ◽  
...  
Keyword(s):  
Liver Enzymes ◽  
Harmful Effect ◽  
Toxic Metal ◽  
Combustion Products ◽  
Blood Parameters ◽  
Living Environment ◽  
The Body ◽  
Lead Contamination ◽  
Lead And Cadmium ◽  
High Level

Heavy metals as pollutants in the working and living environment are a serious health and environmental problem because they are toxic, non-biodegradable, accumulate in living systems and have a long half-life in soil. Sources of lead contamination are combustion products in the chemical industry and metallurgy, industrial waste water, landfills, traffic etc. Lead enters into the body via the food chain and drinking water. In the body lead is deposited in the liver, kidneys, brain and mineral tissues. Excretion of lead causes damage to the epithelial cells of certain organs. High level exposure to cadmium is usually the result of environmental pollution by human activities. Exposure to cadmium can lead to acute and chronic tissue damage of various organs, including liver and kidneys in humans and in animals. In this paper we analyzed the effects of lead and cadmium exposure, in working and living environment, on the model system of experimental animals, particularly the activity of certain liver enzymes, acid and alkaline DNase, and standard biochemical blood parameters. The study showed that lead and cadmium significantly affect the protein content, red blood cells, hemoglobin and hematocrit, and the activity of liver enzymes. This harmful effect of this toxic metal can be reduced by the supplements.

scholarly journals The Relationship Between the Demonstration Method and Active Participation in 3 in 1 Junior Operator Custome Made Women Training

2021 ◽  
Vol 9 (3) ◽  
pp. 398
Author(s):  
Arindha Sukma ◽  
Jamaris Jamna
Keyword(s):  
Sampling Technique ◽  
Simple Random Sampling ◽  
Learning Activities ◽  
Industrial Training ◽  
Level Of Activity ◽  
Analysis Technique ◽  
Correlational Approach ◽  
Good Learning ◽  
Data Collection Technique ◽  
High Level

This research was motivated by the high level of activity of the training participants in participating in the 3 in 1 Junior Operator Custome Made Women's training at the Padang Industrial Training Center, presumably because the instructor used the demonstration method in learning well. This research is quantitative with a correlational approach. The population in this study were all participants of the 3 in 1 Junior Operator Custome Made Women's Training at BDI Padang, totaling 45 people. While the sample was taken using the Simple Random Sampling technique, as many as 88% (40 people) because 12% of the population was used as a test instrument. The data collection technique used a questionnaire distributed via the google form link https://bit.ly/AngketPenelitianArindhaSukma. The data analysis technique used is the percentage formula and the product moment formula. The results of this study indicate that the training participants already have good learning activities, and there is a significant relationship between the demonstration method and the training participants' learning activities.

scholarly journals Etanercept therapy in rheumatoid arthritis: Efficacy and safety

2013 ◽  
Vol 141 (7-8) ◽  
pp. 495-502
Author(s):  
Tatjana Ilic ◽  
Biljana Milic ◽  
Dejan Celic ◽  
Biljana Vuckovic ◽  
Igor Mitic
Keyword(s):  
Rheumatoid Arthritis ◽  
Joint Destruction ◽  
Life Quality ◽  
Activity Level ◽  
Inadequate Response ◽  
Efficacy And Safety ◽  
Etanercept Therapy ◽  
Acr20 Response ◽  
Clinically Significant ◽  
High Level

Introduction. Etanercept, tumor necrosis factor (TNF?) antagonist, lowers the disease activity level in patients with rheumatoid arthritis (RA), reduces joint destruction saving physical functions and improving life quality. Objective. The aim of this study was to establish efficacy and safety of etanercept in combination with disease modifying antirheumatic drugs (DMARDs) in the treatment of RA. Methods. To patients with active RA, who were on therapy with DMARD, etanercept was introduced in weekly doses of 50 mg, with continuation of DMARD. Efficacy of this form of treatment was evaluated in the 12th week. Maintenance of the effect of treatment was also evaluated during 24, 48 and 96 weeks. Long term evaluation of etanercept safety was assessed by registering all unwanted events during a two year period. Results. After 12 weeks of treatment with etanercept, 80% of patients had ACR20 response, while 85% showed clinically significant decrease of DAS28 index. We achieved remission in five patients (12.5%) and low activity of RA in 17 patients (42.5%). During a 96week of followup period, achieved therapy effects were maintained. In four patients (10%) etanercept therapy was interrupted after 24 weeks because of inadequate response. In one of them (2.5%) we recorded a cardiovascular incident. Acute infections were registered in 47 cases. Four of those were severe infections. Neither cases of malignancy development were noted, nor were there any lethal disease outcomes. Conclusion. Etanercept in combination with DMARD shows a high level of efficacy in the treatment of RA. The safety profile of the drug is satisfactory.

scholarly journals Planets and Stellar Activity: Hide and Seek in the CoRoT-7 system

2013 ◽  
Vol 8 (S299) ◽  
pp. 237-240
Author(s):  
R. D. Haywood ◽  
A. C. Cameron ◽  
D. Queloz ◽  
S. C. C. Barros ◽  
M. Deleuil ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Markov Chain ◽  
Precise Determination ◽  
Photometric Data ◽  
Stellar Activity ◽  
Level Of Activity ◽  
Reliable Detection ◽  
Harmonic Decomposition ◽  
High Level

AbstractSince the discovery of the transiting Super-Earth CoRoT-7b, several investigations have been made of the number and precise masses of planets present in the system, but they all yield different results, owing to the star's high level of activity. Radial velocity (RV) variations induced by stellar activity therefore need to be modelled and removed to allow a reliable detection of all planets in the system. We re-observed CoRoT-7 in January 2012 with both HARPS and the CoRoT satellite, so that we now have the benefit of simultaneous RV and photometric data. We fitted the off-transit variations in the CoRoT lightcurve using a harmonic decomposition similar to that implemented in Queloz et al. (2009). This fit was then used to model the stellar RV contribution, according to the methods described by Aigrain et al. (2011). This model was incorporated into a Monte Carlo Markov Chain in order to make a precise determination of the orbits of CoRoT-7b and CoRoT-7c. We also assess the evidence for the presence of one or two additional planetary companions.

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