scholarly journals Apoptosis of human fetal pancreatic islets during short-term culture

2009 ◽  
Vol 61 (1) ◽  
pp. 9-15 ◽  
Author(s):  
P.B. Djordjevic ◽  
Vesna Dimitrijevic-Sreckovic ◽  
V. Bumbasirevic ◽  
R. Colovic ◽  
D. Nikolic ◽  
...  
Keyword(s):  
Pancreatic Islets ◽  
Cell Mass ◽  
Diabetic Patients ◽  
Short Term ◽  
Type 1 Diabetic Patients ◽  
Insulin Secretory Capacity ◽  
Short Term Culture ◽  
Secretory Capacity

We investigated the influence of short-term culture in vitro on the appearance of apoptosis of human fetal pancreatic islets (HFIs) and its effect on the mass and insulin-secretory capacity (ISC) of ?-cells. It was found that apoptosis was present from the end of the culture period, increasing as a function of time and leading to decrease of ?-cell mass. At the same time, ISC decreased. The decrease of ?-cell mass and ISC may influence significantly the clinical outcome of HFIs transplantation in type 1 diabetic patients.

Insulin-mimetic effects of short-term Rapamycin in type 1 diabetic patients prior islet transplantation

2017 ◽  
Author(s):  
Federica Ermetici ◽  
Silvia Briganti ◽  
Stefano Benedini ◽  
Roberto Codella ◽  
Paola Maffi ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Diabetic Patients ◽  
Short Term ◽  
Insulin Mimetic ◽  
Type 1 Diabetic Patients

Activation of human aortic endothelial cells by LDL from Type 1 diabetic patients: an in vitro study

2002 ◽  
Vol 165 (1) ◽  
pp. 69-77 ◽  
Author(s):  
Rosa A Rabini ◽  
Arianna Vignini ◽  
Eleonora Salvolini ◽  
Roberto Staffolani ◽  
Daniela Martarelli ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
In Vitro Study ◽  
Vitro Study ◽  
Diabetic Patients ◽  
Aortic Endothelial Cells ◽  
Type 1 Diabetic Patients ◽  
Human Aortic Endothelial Cells ◽  
Aortic Endothelial

Low-density lipoproteins from type 1 diabetic patients induce in vitro endothelial dysfunction

1999 ◽  
Vol 144 ◽  
pp. 57
Author(s):  
R.A. Rabini ◽  
R. Staffolani ◽  
E. Salvolini ◽  
D. Martarelli ◽  
A. Vignini
Keyword(s):  
Endothelial Dysfunction ◽  
Low Density Lipoproteins ◽  
Diabetic Patients ◽  
Low Density ◽  
Type 1 Diabetic Patients

scholarly journals Increased myocardial contractility in short-term Type 1 diabetic patients: an echocardiographic study

Diabetologia ◽  
1985 ◽  
Vol 28 (11) ◽  
pp. 822-826 ◽  
Author(s):  
L. Thuesen ◽  
J. Sandahl Christiansen ◽  
N. Falstie-Jensen ◽  
C. K. Christensen ◽  
K. Hermansen ◽  
...  
Keyword(s):  
Myocardial Contractility ◽  
Diabetic Patients ◽  
Short Term ◽  
Echocardiographic Study ◽  
Type 1 Diabetic Patients ◽  
Term Type

scholarly journals Low frequency of GITR+ T cells in ex vivo and in vitro expanded Treg cells from type 1 diabetic patients

2013 ◽  
Vol 25 (10) ◽  
pp. 563-574 ◽  
Author(s):  
Cristina Xufré ◽  
Manuela Costa ◽  
Carme Roura-Mir ◽  
Eva Codina-Busqueta ◽  
Lorena Usero ◽  
...  
Keyword(s):  
T Cells ◽  
Ex Vivo ◽  
Low Frequency ◽  
Treg Cells ◽  
Diabetic Patients ◽  
Type 1 Diabetic Patients

scholarly journals Effect of short-term hyperglycaemia on haemodynamics in type 1 diabetic patients

2003 ◽  
Vol 254 (5) ◽  
pp. 464-471 ◽  
Author(s):  
P. Jacobsen ◽  
K. Rossing ◽  
B. V. Hansen ◽  
P. Bie ◽  
A. Vaag ◽  
...  
Keyword(s):  
Diabetic Patients ◽  
Short Term ◽  
Type 1 Diabetic Patients
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