Back in the late 1950s, C.P. Snow famously defined science negatively by separating it from what it was not, namely literature. Such polarization, however, creates more problems than it solves. By contrast, the two co-editors of the book have adopted a dialectical approach to the subject, and to the numerous readers who keep asking themselves “what is science?”, we provide an answer from an early modern perspective, whereby “science” actually includes such various intellectual pursuits as history, poetry, occultism, or philosophy. Each essay illustrates one particular aspect of Shakespeare’s works and links science with the promise of the spectacular. This volume aims at bridging the gap between Renaissance literature and early modern science, focusing as it does on a complex intellectual territory, situated at the point of juncture between humanism, natural magic and craftsmanship. We assume that science and literature constantly interacted with one another, making clear the fact that what we now call “literature” and what we choose to see as “science” were not clearly separated in Shakespeare’s days but rather part of a common intellectual territory.