scholarly journals Anterior ischemic optic neuropathy in a patient with optic disc Drusen while on FOLFOX Chemotherapy for colon cancer: the value of Occam’s Razor and Hickam’s dictum

2019 ◽  
Vol 63 (2) ◽  
pp. 174-177 ◽  
Author(s):  
G. Elnahry Ayman
Keyword(s):  
Colon Cancer ◽  
Optic Disc ◽  
Optic Neuropathy ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy ◽  
Occam’S Razor ◽  
Optic Disc Drusen ◽  
Folfox Chemotherapy ◽  
Occam's Razor

scholarly journals Young Adults With Anterior Ischemic Optic Neuropathy: A Multicenter Optic Disc Drusen Study

2020 ◽  
Vol 217 ◽  
pp. 174-181 ◽  
Author(s):  
Steffen Hamann ◽  
Lasse Malmqvist ◽  
Marianne Wegener ◽  
Masoud Aghsaei Fard ◽  
Valérie Biousse ◽  
...  
Keyword(s):  
Young Adults ◽  
Optic Disc ◽  
Optic Neuropathy ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy ◽  
Optic Disc Drusen

scholarly journals Unilateral Acute Anterior Ischemic Optic Neuropathy in a Patient with an Already Established Diagnosis of Bilateral Optic Disc Drusen

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Ziya Ayhan ◽  
Aylin Yaman ◽  
Meltem Söylev Bajin ◽  
A. Osman Saatci
Keyword(s):  
Optic Disc ◽  
Optic Neuropathy ◽  
Clinical Course ◽  
Vascular Complications ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy ◽  
Vein Occlusion ◽  
Optic Disc Drusen ◽  
Retinal Artery ◽  
Calcific Deposits

Optic disc drusen (ODD) are calcific deposits that form in the optic nerve head secondary to abnormalities in axonal metabolism and degeneration. Anterior ischemic optic neuropathy, central retinal artery, and vein occlusion are among the rare vascular complications of disc drusen. We reported the clinical course of a 51-year-old patient with a unilateral acute nonarteritic anterior ischemic optic neuropathy (NAION) who received the diagnosis of bilateral optic disc drusen five years earlier and thereby reiterated the association of ODD and acute NAION.

Establishing an experimental model of photodynamically induced anterior ischemic optic neuropathy

2011 ◽  
Vol 28 (2) ◽  
pp. 155-162 ◽  
Author(s):  
R.S. WANG ◽  
P.L. LV ◽  
W.J. WANG ◽  
X.D. WANG ◽  
X.J. ZHANG ◽  
...  
Keyword(s):  
Optic Disc ◽  
Optic Neuropathy ◽  
Visual Evoked Potential ◽  
Nerve Fibers ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy ◽  
Fundus Fluorescein Angiography ◽  
Functional Changes ◽  
Depth Study ◽  
Flash Visual Evoked Potential

AbstractNumerous methods and drugs have been used to treat anterior ischemic optic neuropathy (AION); however, further investigations to determine the value of treatments for AION have been impeded by the lack of appropriate animal models of AION, significantly impacting on in-depth study of the disease. A rat model of AION was established, and corresponding functional changes of the fundus were observed using fundus fluorescein angiography (FFA), optical coherence tomography (OCT), and flash visual-evoked potential (F-VEP) in order to confirm the reliability of the AION model histopathologically. One day after model establishment, histopathology demonstrated that portions of the optic disc were highly edematous, with edema of nerve fibers and loose tissue, accompanied by displacement of the surrounding retina. At 23 days, the optic disc and surrounding nerve fiber layers had become thinner. None of the above-mentioned changes was observed in the laser, hematoporphyrin derivative (HPD), or naive groups. The results of fundus, FFA, F-VEP, and OCT—within 90 days after model establishment—confirmed that krypton red laser irradiation (647 nm), applied 2 h after HPD injection, can establish an ideal animal model of AION.

Optic Disc and Peripapillary Morphology in Unilateral Nonarteritic Anterior Ischemic Optic Neuropathy and Age- and Refraction-Matched Normals

Ophthalmology ◽  
2008 ◽  
Vol 115 (9) ◽  
pp. 1585-1590 ◽  
Author(s):  
Hitomi Saito ◽  
Atsuo Tomidokoro ◽  
Goji Tomita ◽  
Makoto Araie ◽  
Masato Wakakura
Keyword(s):  
Optic Disc ◽  
Optic Neuropathy ◽  
Anterior Ischemic Optic Neuropathy ◽  
Ischemic Optic Neuropathy
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