LEP and LEPR Polymorphisms Influences Anthropometric Outcome in Response to 8 Weeks of Combined Training in Obese boys

2021 ◽  
Vol 7 (2) ◽  
Author(s):  
Ali Akbar Jahandideh ◽  
Hadi Rohani ◽  
Hamid Rajabi ◽  
Mohammad Shariatzadeh ◽  
Sahar Razmjou

Background: Weight loss can be influenced by variants of the leptin-encoding genes in obese individuals. The purpose of the present study was to investigate whether LEP19 G>A and LEPR 668 A>G polymorphisms, would influence the effect of an 8-week combined aerobic and resistance training. Methods: Thirty obese boys (BMIz>+2) aged 11-13 (12.66±0.47) were recruited from three middle schools in Quchan. The changes in body composition parameters and metabolic factors in response to 8-weeks combined aerobic and resistance training program were analyzed regarding LEP and LEPR polymorphism. DNA was extracted from cheek cells donated by the 30 participants and genotyping was carried out using PCR. Results: Our results suggest that carriers of rs2167270G allele and rs1137101A allele were characterized by a greater reduction in body mass and WHR (P< 0.05). Also, a significant decrease was observed in leptin levels in carriers of rs2167270G allele after the training program (P=0.031). Moreover, the LEP and LEPR polymorphisms were associated with changes in lipid profile in response to training. Conclusion: In response to 8 weeks of regular physical activity, obese boys with G (rs2167270) and A (rs1137101) alleles had the best likelihood of losing weight which was associated with a decrease in body mass, fat mass (%), WHR and leptin concentrations.

Author(s):  
Kateřina Strašilová ◽  
Petr Vajda ◽  
Tomáš Hlinský

Overweight and obese children often suffer for many physiological and psychological is-sues. Resistance training allows them to excel over their peers due to strength ability which is related to their somatotype. The aim of this study was to examine the effect of an eight-week resistance training program on body composition in overweight and obese children. Study sample included 8 boys and 4 girls (age = 11.7 ± 1.54) who were involved in an eight-week strength specifically designed program consisted of two strength training unit per week. Resistance of exercise was set on 8‒10 RM. Body composition were measured by InBody 720 two times before and after the training intervention. The Wilcoxon matched pairs test was used. Results showed increase in total body weight (2.7%), lean body mass (2.5%) and fat mass (3.7%). This effect indicates that used resistance training program is suficient to lean body mass grow. Nevertheless, program proved to be inadequate to avoid an increase in fat mass. This could be caused by many factors which should be consider in further research (e.g. longer technique practice, diet, number of training units).


2014 ◽  
Vol 6 (1) ◽  
pp. 74-85 ◽  
Author(s):  
Anne Cabral ◽  
Íris Magalhães ◽  
Cláudio Borba-Pinheiro ◽  
Olavo Rocha-Júnior ◽  
Nébia Figueiredo ◽  
...  

2009 ◽  
Vol 41 ◽  
pp. 130-131
Author(s):  
José A. Pérez-Turpin ◽  
Juan M. Cortell-Tormo ◽  
Pablo Tercedor-Sánchez ◽  
Alfonso Jiménez ◽  
Juan J. Chinchilla-Mira

Author(s):  
Jessica M. Moon ◽  
Kayla M. Ratliff ◽  
Julia C. Blumkaitis ◽  
Patrick S. Harty ◽  
Hannah A. Zabriskie ◽  
...  

Abstract Background Large (48-g), isonitrogenous doses of rice and whey protein have previously been shown to stimulate similar adaptations to resistance training, but the impact of consuming smaller doses has yet to be compared. We evaluated the ability of 24-g doses of rice or whey protein concentrate to augment adaptations following 8 weeks of resistance training. Methods Healthy resistance-trained males (n = 24, 32.8 ± 6.7 years, 179.3 ± 8.5 cm, 87.4 ± 8.5 kg, 27.2 ± 1.9 kg/m2, 27.8 ± 6.0% fat) were randomly assigned and matched according to fat-free mass to consume 24-g doses of rice (n = 12, Growing Naturals, LLC) or whey (n = 12, NutraBio Labs, Inc.) protein concentrate for 8 weeks while completing a standardized resistance training program. Body composition (DXA), muscular strength (one-repetition maximum [1RM]) and endurance (repetitions to fatigue [RTF] at 80% 1RM) using bench press (BP) and leg press (LP) exercises along with anaerobic capacity (Wingate) were assessed before and after the intervention. Subjects were asked to maintain regular dietary habits and record dietary intake every 2 weeks. Outcomes were assessed using 2 × 2 mixed (group x time) factorial ANOVA with repeated measures on time and independent samples t-tests using the change scores from baseline. A p-value of 0.05 and 95% confidence intervals on the changes between groups were used to determine outcomes. Results No baseline differences (p > 0.05) were found for key body composition and performance outcomes. No changes (p > 0.05) in dietary status occurred within or between groups (34 ± 4 kcal/kg/day, 3.7 ± 0.77 g/kg/day, 1.31 ± 0.28 g/kg/day, 1.87 ± 0.23 g/kg/day) throughout the study for daily relative energy (34 ± 4 kcals/kg/day), carbohydrate (3.7 ± 0.77 g/kg/day), fat (1.31 ± 0.28 g/kg/day), and protein (1.87 ± 0.23 g/kg/day) intake. Significant main effects for time were revealed for body mass (p = 0.02), total body water (p = 0.01), lean mass (p = 0.008), fat-free mass (p = 0.007), BP 1RM (p = 0.02), BP volume (p = 0.04), and LP 1RM (p = 0.01). Changes between groups were similar for body mass (− 0.88, 2.03 kg, p = 0.42), fat-free mass (− 0.68, 1.99 kg, p = 0.32), lean mass (− 0.73, 1.91 kg, p = 0.37), fat mass (− 0.48, 1.02 kg, p = 0.46), and % fat (− 0.63, 0.71%, p = 0.90). No significant between group differences were seen for BP 1RM (− 13.8, 7.1 kg, p = 0.51), LP 1RM (− 38.8, 49.6 kg, p = 0.80), BP RTF (− 2.02, 0.35 reps, p = 0.16), LP RTF (− 1.7, 3.3 reps, p = 0.50), and Wingate peak power (− 72.5, 53.4 watts, p = 0.76) following the eight-week supplementation period. Conclusions Eight weeks of daily isonitrogenous 24-g doses of rice or whey protein in combination with an eight-week resistance training program led to similar changes in body composition and performance outcomes. Retroactively registered on as NCT04411173.


2017 ◽  
Vol 49 (5S) ◽  
pp. 259
Author(s):  
Straughn Marisa ◽  
John D. Wallop ◽  
Lauren Adlof ◽  
Amy Crawley ◽  
Ludmila Cosio-Lima

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12189
Author(s):  
Jason Sawyer ◽  
Paul Higgins ◽  
Paul A. Cacolice ◽  
Troy Doming

Background Optimizing training adaptations is of the utmost importance for the strength and conditioning professional. The pre-season of any sport is particularly important to ensure preparedness of the athletes. In DIII Collegiate Football pre-season consists of approximately 3 weeks. The abbreviated time of the pre-season increases the importance of optimizing training using safe methods, including alternative loading strategies. The purpose of the current study was to determine if a 3-week variable resistance training VRT during an undulating (UL) resistance training program elicited a greater increase in back squat strength compared to traditional loading methods. Methods and Materials Forty DIII Football players (age range: 18–25 years) participated in a 3-week UL bilateral back squat (BBS) program. Both groups performed the BBS 3 times per week with a minimum of 24 hours between exercise sessions. The control group (C) (n = 20) (height = 182.3 + 5.1 cm, body mass: pre = 102.8 ± 17.7 kg, post = 104.1 ± 17.8 kg) used traditional loading methods (i.e., Olympic weights only) and the experimental group (E) (n = 20) (height = 180.7 ± 8.0 cm, body mass: pre = 100.3 ± 27.1 kg, post = 101.0 ± 27.7 kg) used traditional loading methods and variable resistance (i.e., resistance bands). The variable resistance accounted for approximately 20% of the total resistance while 80% of the resistance was supplied by traditional loading methods. Results When all data was pooled, subjects had a significant increase (p < 0.05) in 1-RM BBS from pre (154.2 + 26.1 kg) to post (166.8 + 26.2 kg), with a percent increase of 8.13% at the completion of the 3-week training program. There was no significant difference (p > 0.05) between the C and E groups for muscular strength, muscular power, or vertical jump. Volume-loads were not significantly (p > 0.05) different between groups for any of the weeks (C: Week 1 = 858.1 + 101.3, Week 2 = 588.6 + 69.2, Week 3 = 332.5 + 38.9, Total = 1179.2 + 209.4 vs. E: Week 1 = 835.2 + 179.7, Week 2 = 572.2 + 123.4, Week 3 = 323.5 + 68.8, Total = 1730.9 + 371.8) or for the pre-season as a whole. Conclusion A traditional UL resistance training program and training program with variable resistance are both effective methods at increasing back squat strength during 3 weeks of training. Resistance band variable resistance (VR) does not enhance training effects within a 3-week mesocycle greater than traditional resistance.


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