On the frequency of diabetes mellitus and glucose intolerance in patients with cystic fibrosis

2001 ◽  
Vol 77 (4) ◽  
pp. 321-26 ◽  
Author(s):  
Flávia A.A. de Castro ◽  
Maria I.M. Fernandes ◽  
Renan M. Montenegro Júnior ◽  
Milton C. Foss
Keyword(s):  
Diabetes Mellitus ◽  
Cystic Fibrosis ◽  
Glucose Intolerance

Gastric Inhibitory Polypeptide Release after Oral Glucose: Relationship to Glucose Intolerance, Diabetes Mellitus, and Obesity

1982 ◽  
Vol 55 (2) ◽  
pp. 329-336 ◽  
Author(s):  
MARCELLO SALERA ◽  
PIERLUIGI GIACOMONI ◽  
LORIS PIRONI ◽  
GIANLUCA CORNIA ◽  
MAURIZIO CAPELLI ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Intolerance ◽  
Gastric Inhibitory Polypeptide ◽  
Oral Glucose

Low prevalence of glucose intolerance in racially mixed children with cystic fibrosis

2010 ◽  
Vol 11 (7) ◽  
pp. 493-497
Author(s):  
Crésio Alves ◽  
Daniela S Lima ◽  
Mauricio Cardeal ◽  
Angelica Santana
Keyword(s):  
Cystic Fibrosis ◽  
Glucose Intolerance ◽  
Racially Mixed ◽  
Low Prevalence

Diabetes Mellitus in Patients With Cystic Fibrosis: Effect on Survival

PEDIATRICS ◽  
1990 ◽  
Vol 86 (3) ◽  
pp. 374-377
Author(s):  
J. Reisman ◽  
M. Corey ◽  
G. Canny ◽  
H. Levison
Keyword(s):  
Diabetes Mellitus ◽  
Cystic Fibrosis ◽  
Survival Analysis ◽  
Nutritional Status ◽  
Pulmonary Function ◽  
Survival Data ◽  
Diabetes Diagnosis ◽  
Patients With Diabetes ◽  
Insulin Dependent ◽  
Sick Children

Patient data obtained from the cystic fibrosis clinic of the Hospital for Sick Children (Toronto, Canada) over the period 1977 to 1988 were analyzed to compare the diabetic and nondiabetic cystic fibrosis patients. The pulmonary function, nutritional status, and survival data for 713 patients who attended the clinic over the 11-year period are reported. Insulin-dependent diabetes was found to exist in 37 (5.2%) of 713 patients. The patient age at time of diabetes diagnosis ranged from 2 to 34 years, with a mean ± SD of 20.0 ± 7.4 years. Patients who died in both the diabetic and nondiabetic groups had worse pulmonary and nutritional status than the surviving patients, but there were no significant differences between the diabetic and nondiabetic groups in those who died or in those who remained alive. Survival analysis showed a similar prognosis in the diabetic and nondiabetic groups. It is concluded that cystic fibrosis patients with diabetes are, for their age, not different from patients without diabetes with respect to pulmonary function, nutritional status, and survival.

scholarly journals Investigation of the progress in the women with gestational diabetes mellitus postpartum

2021 ◽  
pp. 45-51
Author(s):  
Thi To Nhu Phan ◽  
Trung Vinh Hoang
Keyword(s):  
Diabetes Mellitus ◽  
Logistic Regression ◽  
Glucose Tolerance ◽  
Beta Cell ◽  
Glucose Intolerance ◽  
Beta Cell Function ◽  
Cell Function ◽  
Postpartum Women ◽  
Matsuda Index ◽  
History Of

Aims: Our aim was to evaluate the uptake of postpartum screening, the prevalence and the risk factors for glucose intolerance in women with a recent history of gestational diabetes mellitus (GDM). Methods: All women with a history of GDM are advised to undergo a 75g oral glucose tolerance test (OGTT) around 6 - 12 weeks postpartum. Indices of insulin sensitivity (the Matsuda index and the reciprocal of the homeostasis model assessment of insulin resistance, HOMA-IR) and an index of beta-cell function, the Insulin Secretion-Sensitivity Index-2 (ISSI-2) were calculated based on the OGTT postpartum. Multivariable logistic regression was used to some factors. Results: Of all women (135) who received an OGTT postpartum, 42.2% (57) had glucose intolerance (11.8% impaired fasting glucose, 24.4% impaired glucose tolerance and 6.0% both impaired fasting and impaired glucose tolerance) and 1.5% (2) had overt diabetes. Compared to women with a normal OGTT postpartum, women with glucose intolerance and diabetes were older (32.5 ± 4.3 vs. 30.8 ± 4.8 years, p = 0.049), were more often obese (34.5% vs. 17.3%, p = 0.023). In the multivariable logistic regression, an EM background [OR = 2.76 (1.15 - 6.62), p = 0.023] and the HbA1c level at the time of the OGTT in pregnancy [OR = 4.78 (1.19 - 19.20), p = 0.028] remained significant predictors for glucose intolerance postpartum. Women with glucose intolerance and diabetes postpartum had a similar insulin sensitivity [Matsuda index 0.656 (0.386 - 1.224) vs. 0.778 (0.532 - 1.067), p = 0.709; HOMA-IR 0.004 (0.002 - 0.009) vs. 0.064 (0.003 - 0.007), p = 0.384] but a lower beta-cell function compared to women with a normal OGTT postpartum, remaining significant after adjustment for confounders [ISSI-2 1.6 (1.2 - 2.1) vs. 1.9 (1.7 - 2.4), p = 0.002]. Conclusions: Glucose intolerance is very frequent in early postpartum in women with GDM these women have an impaired beta-cell function. Nearly one third of women did not attend the scheduled OGTT postpartum and these women have an adverse risk profile. More efforts are needed to engage and stimulate women with GDM to attend the postpartum OGTT.

Genetic determination of diabetes mellitus in patients with cystic fibrosis

1995 ◽  
Vol 127 (3) ◽  
pp. 441-443 ◽  
Author(s):  
Joseph Rosenecker ◽  
Irmgard Eichler ◽  
Ludwig Kühn ◽  
Hinrich K. Harms ◽  
Horst von der Hardt
Keyword(s):  
Diabetes Mellitus ◽  
Cystic Fibrosis ◽  
Genetic Determination

Glucose concentration in parotid saliva after glucose/food intake in individuals with glucose intolerance and diabetes mellitus

1998 ◽  
Vol 106 (5) ◽  
pp. 931-937 ◽  
Author(s):  
Annika Borg Andersson ◽  
Dowen Birkhed ◽  
Kerstin Berntorp ◽  
Folke Lindgärde ◽  
Lars Matsson
Keyword(s):  
Diabetes Mellitus ◽  
Food Intake ◽  
Glucose Intolerance ◽  
Glucose Concentration ◽  
Parotid Saliva

scholarly journals Antibodies to Human HSP60 in Patients with Juvenile Chronic Arthritis, Diabetes Mellitus, and Cystic Fibrosis

1993 ◽  
Vol 34 (4) ◽  
pp. 424-428 ◽  
Author(s):  
E R de Graeff-Meeder ◽  
G T Rijkers ◽  
M M Voorhorst-Ogink ◽  
W Kuis ◽  
R van der Zee ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cystic Fibrosis ◽  
Juvenile Chronic Arthritis ◽  
Chronic Arthritis ◽  
Human Hsp60

Glucose Intolerance in Cystic Fibrosis of the Pancreas1

2015 ◽  
pp. 172-179
Author(s):  
Stuart Handwerger ◽  
Jesse Roth
Keyword(s):  
Cystic Fibrosis ◽  
Glucose Intolerance
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