scholarly journals Risk factors for gastroesophageal reflux disease in very low birth weight infants with bronchopulmonary dysplasia

2008 ◽  
Vol 84 (2) ◽  
pp. 154-159 ◽  
Author(s):  
Thaís B. Mendes ◽  
Maria Aparecida M.S. Mezzacappa ◽  
Adyléia A. D. C. Toro ◽  
José Dirceu Ribeiro
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Gastroesophageal Reflux Disease ◽  
Low Birth Weight ◽  
Gastroesophageal Reflux ◽  
Bronchopulmonary Dysplasia ◽  
Reflux Disease ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants

scholarly journals Risk factors and clinical characteristics for bronchopulmonary dysplasia associated pulmonary hypertension in very-low-birth-weight infants

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Junfang Sun ◽  
Bowen Weng ◽  
Xiaoyue Zhang ◽  
Xiaoyun Chu ◽  
Cheng Cai
Keyword(s):  
Risk Factors ◽  
Pulmonary Hypertension ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Bronchopulmonary Dysplasia ◽  
Clinical Characteristics ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Average Birth Weight ◽  
Specific Risk

Abstract Background Pulmonary hypertension (PH) is a common complication of bronchopulmonary dysplasia (BPD) in very-low-birth-weight infants (VLBWIs). Although recent studies have increased awareness that PH contributes significantly to the high morbidity and mortality of BPD, the risk factors and clinical characteristics for PH in VLBWIs are little known. Objectives To investigate the risk factors and clinical characteristics for BPD-associated pulmonary hypertension (BPD-PH) in VLBWIs. Methods A retrospective case–control observational study of VLBWIs with BPD admitted to a neonatal intensive care unit (NICU) over 4 years. According to echocardiograms confirming elevated pulmonary artery pressure after 28 days after birth, we divided BPD infants into PH group (n = 18) and non-PH group (n = 65). We compared pre- and postnatal characteristics between VLBWIs with or without PH. Multivariable logistic regression analysis was conducted with backward selection. Results A total of 83 infants with BPD were divided into PH group (n = 18) or non-PH group (n = 65). The average birth weight of the infants with BPD was 1078.1 g. Compared with those infants of the non-PH group, the birth weight of BPD-PH infants was significantly lower (968.1 ± 187.7 vs. 1108.5 ± 185.8, P = 0.006). Infants in the PH group had a higher incidence of patent ductus arteriosus (PDA) and underwent longer durations of oxygen therapy and mechanical ventilation compared to those in the non-PH group. In all subjects, birth weight (OR 0.995; 95% CI 0.991–0.999; P = 0.025) and PDA (OR 13.355; 95% CI 2.950–60.469; P = 0.001) were found to be specific risk factors for BPD-PH in this cohort. Conclusions The study shows PDA and birth weight are specific risk factors for BPD-PH in VLBWIs.

scholarly journals Recent Changes in the Incidence of Bronchopulmonary Dysplasia among Very-Low-Birth-Weight Infants in Korea

2015 ◽  
Vol 30 (Suppl 1) ◽  
pp. S81 ◽  
Author(s):  
Heui Seung Jo ◽  
Kee Hyun Cho ◽  
Sung-Il Cho ◽  
Eun Song Song ◽  
Beyong Il Kim
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Bronchopulmonary Dysplasia ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants
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