Evaluation of peak inspiratory pressure and respiratory rate during ventilation of an infant lung model with a self-inflating bag

2006 ◽  
Vol 0 (0) ◽  
Author(s):  
Jefferson G. Resende ◽  
Cristiane G. Menezes ◽  
Ana M. C. Paula ◽  
Antônio C. P. Ferreira ◽  
Carlos A. M. Zaconeta ◽  
...  
2006 ◽  
Vol 82 (4) ◽  
pp. 279-283 ◽  
Author(s):  
Jefferson G. Resende ◽  
Carlos A. M. Zaconeta ◽  
Antônio C. P. Ferreira ◽  
César A. M. Silva ◽  
Marcelo P. Rodrigues ◽  
...  

2020 ◽  
Author(s):  
Tatsutoshi Shimatani ◽  
Benjamin Yoon ◽  
Miyako Kyogoku ◽  
Michihito Kyo ◽  
Shinichiro Ohshimo ◽  
...  

Abstract [BACKGROUND] Reverse triggering (RT) occurs when respiratory effort begins after a mandatory breath is initiated by the ventilator. RT may exacerbate ventilator-induced lung injury and lead to breath stacking. We sought to describe the frequency and risk factors for RT amongst ARDS patients and identify risk factors for breath-stacking. [METHODS] Secondary analysis of physiologic data from children on Synchronized Intermittent Mandatory pressure control ventilation enrolled in a single center RCT for ARDS. When children had a spontaneous effort on esophageal manometry, waveforms were recorded and independently analyzed by two investigators to identify RT. [RESULTS] We included 81,990 breaths from 100 patient-days and 36 patients. Overall, 2.46% of breaths were RTs, occurring in 15/36 patients (41.6%). Higher tidal volume and a minimal difference between neural respiratory rate and set ventilator rate were independently associated with RT (p = 0.001) in multivariable modeling. Breath stacking occurred in 534 (26.5%) of 2017 RT breaths, and 14 (93.3%) of 15 RT patients. In multivariable modeling, breath stacking was more likely to occur when total airway delta pressure (Peak Inspiratory Pressure-PEEP) at the time patient effort began, Peak Inspiratory Pressure, PEEP, and Delta Pressure were lower, and when patient effort started well after the ventilator initiated breath (higher phase angle) (all p < 0.05). Together these parameters were highly predictive of breath stacking (AUC 0.979). [CONCLUSIONS] Patients with higher tidal volume and who have a set ventilator rate close to their spontaneous respiratory rate are more likely to have RT, which results in breath stacking over 25% of the time. Trial registration: NIH/NHLBI R01HL124666, Clinical Trials.gov NCT03266016, Registered 29 August 2017, https://clinicaltrials.gov/ct2/show/NCT03266016


1990 ◽  
Vol 65 (10 Spec No) ◽  
pp. 1045-1049 ◽  
Author(s):  
K D Foote ◽  
A H Hoon ◽  
S Sheps ◽  
N R Gunawardene ◽  
R Hershler ◽  
...  

1982 ◽  
Vol 53 (4) ◽  
pp. 901-907 ◽  
Author(s):  
J. G. Burdon ◽  
K. J. Killian ◽  
E. J. Campbell

Using open-magnitude scaling we studied the importance of ventilatory drive on the perceived magnitude of respiratory loads by applying a range of externally added resistances (2.1–77.1 cmH2O X l-1 X s) to normal subjects at rest and at three increasing levels of ventilatory drive induced by exercise, CO2-stimulated breathing, and hypoxia. Under all conditions studied the perceived magnitude of the added loads increased with the magnitude of the resistive load and as the underlying level of ventilatory drive increased. When the results were expressed in terms of peak inspiratory pressure, the perceived magnitude was related to the magnitude of the peak inspiratory pressure by a power function (mean r = 0.97). These results suggest that the perceived magnitude of added resistive loads increased with increasing ventilatory drive, in such a manner that the increase in sensory magnitude is proportional to the increase in the inspiratory muscle force developed and suggests that something dependent on this force mediates the sensation.


Author(s):  
Anake Pomprapa ◽  
Soren Weyer ◽  
Steffen Leonhardt ◽  
Marian Walter ◽  
Berno Misgeld

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