scholarly journals Biochemical modification of titanium surfaces: Peptides and eCM proteins

2006 ◽  
Vol 12 ◽  
pp. 1-15 ◽  
Author(s):  
M Morra
Keyword(s):  
Biochemical Modification ◽  
Ecm Proteins ◽  
Titanium Surfaces ◽  
Modification Of Titanium

scholarly journals Covalently-Linked Hyaluronan versus Acid Etched Titanium Dental Implants: A Crossover RCT in Humans

2019 ◽  
Vol 20 (3) ◽  
pp. 763 ◽  
Author(s):  
Saturnino Lupi ◽  
Arianna Rodriguez y Baena ◽  
Clara Cassinelli ◽  
Giorgio Iviglia ◽  
Marco Tallarico ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Dental Implants ◽  
Clinical Success ◽  
Molecular Layer ◽  
Host Responses ◽  
Biochemical Modification ◽  
Bone Level ◽  
Titanium Surfaces ◽  
Covalently Linked ◽  
Modification Of Titanium

Biochemical modification of titanium surfaces (BMTiS) entails immobilization of biomolecules to implant surfaces in order to induce specific host responses. This crossover randomized clinical trial assesses clinical success and marginal bone resorption of dental implants bearing a surface molecular layer of covalently-linked hyaluronan in comparison with control implants up to 36 months after loading. Patients requiring bilateral implant rehabilitation received hyaluronan covered implants in one side of the mouth and traditional implants in the other side. Two months after the first surgery, a second surgery was undergone to uncover the screw and to place a healing abutment. After two weeks, the operator proceeded with prosthetic procedures. Implants were evaluated by periapical radiographs and the crestal bone level was recorded at mesial and distal sites—at baseline and up to 36 months. One hundred and six implants were positioned, 52 HY-coated, and 48 controls were followed up. No differences were observed in terms of insertion and stability, wound healing, implant success, and crestal bone resorption at any time considered. All interventions had an optimal healing, and no adverse events were recorded. This trial shows, for the first time, a successful use in humans of biochemical-modified implants in routine clinical practice and in healthy patients and tissues with satisfactory outcomes.

scholarly journals Modification of titanium surfaces by adding antibiotic-loaded PHB spheres and PEG for biomedical applications

2016 ◽  
Vol 27 (8) ◽  
Author(s):  
Alejandra Rodríguez-Contreras ◽  
María Soledad Marqués-Calvo ◽  
Francisco Javier Gil ◽  
José María Manero
Keyword(s):  
Biomedical Applications ◽  
Titanium Surfaces ◽  
Modification Of Titanium

Femtosecond laser modification of titanium surfaces: direct imprinting of hydroxylapatite nanopowder and wettability tuning via surface microstructuring

2013 ◽  
Vol 10 (4) ◽  
pp. 045605 ◽  
Author(s):  
Andrey A Ionin ◽  
Sergey I Kudryashov ◽  
Sergey V Makarov ◽  
Pavel N Saltuganov ◽  
Leonid V Seleznev ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Laser Modification ◽  
Titanium Surfaces ◽  
Modification Of Titanium

Calcium Titanate Film-Coating on Titanium with Hydrothermal Treatments

2007 ◽  
Vol 330-332 ◽  
pp. 737-740 ◽  
Author(s):  
Masayuki Kon ◽  
Razia Sultana ◽  
Emi Fujihara ◽  
Kenzo Asaoka ◽  
Tetsuo Ichikawa
Keyword(s):  
High Pressure ◽  
Surface Modification ◽  
Simulated Body Fluid ◽  
Body Fluid ◽  
Titanium Surface ◽  
Film Coating ◽  
Calcium Titanate ◽  
Maximal Pressure ◽  
Titanium Surfaces ◽  
Modification Of Titanium

Film-coating on the surface of titanium was investigated by hydrothermal treatments with a maximal pressure of 6.3 MPa (280°C) in CaO solution and water to improve bioactivity and biocompatibility. As a result, calcium titanate (CaTiO3) film was formed on the titanium surface. The surface-coated titanium was immersed in a simulated body fluid (SBF) to estimate its bioactivity. Apatite precipitation was observed on all hydrothermal-treated titanium surfaces after immersion in SBF for 4 weeks. In particular, the apatite precipitation of titanium treated with 6.3 MPa in CaO solution was clearer and larger in amount than those of all other hydrothermal-treated specimens. The results suggest that surface modification of titanium with high-pressure hydrothermal treatments can be expected to improve bioactivity and biocompatibility.

Biomimetic surface modification of titanium surfaces for early cell capture by advanced electrospinning

2011 ◽  
Vol 7 (1) ◽  
pp. 015001 ◽  
Author(s):  
Rajeswari Ravichandran ◽  
Clarisse CH Ng ◽  
Susan Liao ◽  
Damian Pliszka ◽  
Michael Raghunath ◽  
...  
Keyword(s):  
Surface Modification ◽  
Cell Capture ◽  
Biomimetic Surface ◽  
Titanium Surfaces ◽  
Modification Of Titanium

Hydrothermal Modification of Titanium Surfaces for Controlling Osteointegration

2010 ◽  
Vol 638-642 ◽  
pp. 724-729
Author(s):  
Masato Ueda ◽  
Takahiro Kinoshita ◽  
Yuumi Sasaki ◽  
Masahiko Ikeda ◽  
Michiharu Ogawa
Keyword(s):  
Body Fluid ◽  
Oxide Films ◽  
Incipient Stage ◽  
Hydrothermal Modification ◽  
Gel Layer ◽  
Titanium Surfaces ◽  
Tio2 Gel ◽  
Free Films ◽  
Modification Of Titanium ◽  
Perovskite Type

The combined chemical-hydrothermal synthesis of TiO2 and CaTiO3 films on pure Ti substrates was examined with a focus on film crystallinity and surface morphology. Pure Ti disks were chemically treated with H2O2/ HNO3 aqueous solutions at 353 K for 20 min in order to form a TiO2 gel layer on the surfaces. The samples were then hydrothermally treated in an autoclave at 453 K for 12 h or 24 h. Anatase-type TiO2 and perovskite-type CaTiO3 films with high crystallinity were obtained upon treatment with distilled water or aqueous NH3 and aqueous Ca(OH)2, respectively. Uniform, crack-free films were obtained. The surfaces showed excellent attachment of osteoblast-like MC3T3E1 cells in an incipient stage. Furthermore, the cells showed satisfactory proliferation, though at a slightly lower rate than on Ti. In addition, the samples were immersed in SBF (Simulated Body Fluid), adjusted to 310 K. A light hydroxyapatite (HAp) precipitate was observed on the unmodified Ti surface after 6 days of immersion. In contrast, precipitation was observed only after 2 to 4 days on the present oxide films. Thus, these oxide films are non-toxic and enhance the deposition of HAp.

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