scholarly journals Novel observations of peroxiredoxin-2 profile and protein oxidation in skeletal muscle from pigs of differing residual feed intake and health status

2021 ◽  
Author(s):  
Amanda C Outhouse ◽  
Brian M Patterson ◽  
Edward M;. Steadham ◽  
Elisabeth J. Huff-Lonergan ◽  
Emma T Helm ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Health Status ◽  
Feed Intake ◽  
Protein Oxidation ◽  
Residual Feed Intake ◽  
Peroxiredoxin 2

scholarly journals Novel Observations of Peroxiredoxin-2 Profile and Protein Oxidation in Skeletal Muscle from Pigs that Differ In Residual Feed Intake and Health Status

2018 ◽  
Vol 2 (2) ◽  
pp. 171-171
Author(s):  
B. M. Patterson ◽  
A. C. Outhouse ◽  
E. T. Helm ◽  
J. C. M. Dekkers ◽  
K. J. Schwartz ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Health Status ◽  
Feed Intake ◽  
Protein Oxidation ◽  
Residual Feed Intake ◽  
Peroxiredoxin 2

scholarly journals An examination of skeletal muscle and hepatic tissue transcriptomes from beef cattle divergent for residual feed intake 

2020 ◽  
Author(s):  
Clare McKenna ◽  
Kate Keogh ◽  
Richard Porter ◽  
Sinead Waters ◽  
Paul Cormican ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Residual Feed Intake ◽  
Transcriptome Profiling ◽  
Nucleotide Metabolism ◽  
Differentially Expressed ◽  
Physiological Age ◽  
Hepatic Tissue ◽  
Molecular Control

Abstract The selection of cattle with enhanced feed efficiency is of paramount importance with regard to reducing feed costs in the beef industry. Global transcriptome profiling was undertaken on liver and skeletal muscle biopsies from Simmental heifers and bulls divergent in residual feed intake (RFI) feed efficiency phenotype, in order to identify genes that may be associated with this trait. We identified 5 genes (adj.p<0.1) to be differentially expressed in skeletal muscle between high and low RFI heifers with all transcripts involved in oxidative phosphorylation and mitochondrial homeostasis. A total of 11 genes (adj.p<0. 1) were differentially expressed in liver tissue between high and low RFI bulls with differentially expressed genes related to amino and nucleotide metabolism as well as endoplasmic reticulum protein processing. No genes were identified as differentially expressed in either heifer liver or bull muscle analyses. Results from this study show a clear effect of gender to the underlying molecular control of RFI in cattle, which may be attributable to differences in the physiological age between heifers and bulls. Despite this we have highlighted a number of genes that may hold potential as molecular biomarkers for RFI cattle.

scholarly journals An examination of skeletal muscle and hepatic tissue transcriptomes from beef cattle divergent for residual feed intake

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Clare McKenna ◽  
Kate Keogh ◽  
Richard K. Porter ◽  
Sinead M. Waters ◽  
Paul Cormican ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Residual Feed Intake ◽  
Transcriptome Profiling ◽  
Nucleotide Metabolism ◽  
Differentially Expressed ◽  
Hepatic Tissue ◽  
Molecular Control ◽  
Feed Costs

AbstractThe selection of cattle with enhanced feed efficiency is of importance with regard to reducing feed costs in the beef industry. Global transcriptome profiling was undertaken on liver and skeletal muscle biopsies from Simmental heifers and bulls divergent for residual feed intake (RFI), a widely acknowledged feed efficiency phenotype, in order to identify genes that may be associated with this trait. We identified 5 genes (adj. p < 0.1) to be differentially expressed in skeletal muscle between high and low RFI heifers with all transcripts involved in oxidative phosphorylation and mitochondrial homeostasis. A total of 11 genes (adj. p < 0. 1) were differentially expressed in liver tissue between high and low RFI bulls with differentially expressed genes related to amino and nucleotide metabolism as well as endoplasmic reticulum protein processing. No genes were identified as differentially expressed in either heifer liver or bull muscle analyses. Results from this study show that the molecular control of RFI in young cattle is modified according to gender, which may be attributable to differences in physiological maturity between heifers and bulls of the same age. Despite this we have highlighted a number of genes that may hold potential as molecular biomarkers for RFI cattle.

scholarly journals Mitochondrial abundance and function in skeletal muscle and liver from Simmental beef cattle divergent for residual feed intake

animal ◽  
2020 ◽  
Vol 14 (8) ◽  
pp. 1710-1717
Author(s):  
C. McKenna ◽  
R.K. Porter ◽  
C. Fitzsimons ◽  
S.M. Waters ◽  
M. McGee ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Beef Cattle ◽  
Feed Intake ◽  
Residual Feed Intake ◽  
And Function

scholarly journals Differentially expressed mRNAs, proteins and miRNAs associated to energy metabolism in skeletal muscle of beef cattle identified for low and high residual feed intake

BMC Genomics ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Elisa B. Carvalho ◽  
Mateus P. Gionbelli ◽  
Rafael T. S. Rodrigues ◽  
Sarah F. M. Bonilha ◽  
Charles J. Newbold ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Energy Metabolism ◽  
Beef Cattle ◽  
Feed Intake ◽  
Residual Feed Intake ◽  
Differentially Expressed

scholarly journals Effect of Gender and Residual Feed Intake Phenotype on the Transcriptome of Liver and Skeletal Muscle Tissue in Purebred Simmental Beef Cattle

2020 ◽  
Author(s):  
Clare McKenna ◽  
Kate Keogh ◽  
Richard K. Porter ◽  
Sinead M. Waters ◽  
Paul Cormican ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Differentially Expressed Genes ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Cell Signalling ◽  
Residual Feed Intake ◽  
Differentially Expressed ◽  
Physiological Age ◽  
Hepatic Tissue ◽  
Molecular Control

Abstract Background: The selection of cattle with enhanced feed efficiency is of paramount importance with regard to reducing feed costs in the beef industry. However the role, if any, of gender to the underlying molecular control of feed efficiency in cattle is not currently known. Global transcriptome profiling was undertaken on liver and skeletal muscle biopsies from Simmental heifers and bulls divergent in residual feed intake (RFI) feed efficiency phenotype, in order to identify differentially expressed genes that may be associated with this trait. Results: We identified 5 genes (p<0.001; false discovery rate (FDR) <0.1) to be differentially expressed in skeletal muscle between high and low RFI heifers with all 5 transcripts being up-regulated in the low RFI phenotype. Among these differentially expressed genes, all transcripts were involved in oxidative phosphorylation and mitochondrial homeostasis. A total of 11 genes (p<0.001;FDR <0.1) were differentially expressed in hepatic tissue between high and low RFI bulls with 8 transcripts being up-regulated and 3 being down-regulated in the low RFI phenotype. These differentially expressed genes were related to oxidative response, protein mediation and cell signalling. No genes were identified as differentially expressed in both heifer liver and bull muscle analyses. Conclusions: Results from this study show a clear effect of gender to the underlying molecular control of RFI in cattle, which may be attributable to differences in the physiological age between heifers and bulls. Despite this we have highlighted a number of genes that may hold potential as molecular biomarkers for RFI cattle.

Relationship between residual feed intake, protein oxidation, and protein degradation in pigs

Meat Science ◽  
2014 ◽  
Vol 96 (1) ◽  
pp. 470-471
Author(s):  
R.M. Punt ◽  
A.M. Blakely⁎ ◽  
J.K. Grubbs ◽  
S.M. Cruzen ◽  
E. Huff-Lonergan ◽  
...  
Keyword(s):  
Protein Degradation ◽  
Feed Intake ◽  
Protein Oxidation ◽  
Residual Feed Intake

Transcriptome Analysis of Skeletal Muscle in Pigs with Divergent Residual Feed Intake Phenotypes

2020 ◽  
Vol 39 (3) ◽  
pp. 404-416 ◽  
Author(s):  
Xinhua Hou ◽  
Lei Pu ◽  
Ligang Wang ◽  
Xin Liu ◽  
Hongmei Gao ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Transcriptome Analysis ◽  
Feed Intake ◽  
Residual Feed Intake
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