scholarly journals Influence of Post-Harvest Circulatory Rinse on Tenderness and Objective Color of Cow Striploin Steaks

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
L. M. Hite ◽  
J. K. Grubbs ◽  
A. D. Blair ◽  
K. R. Underwood
Keyword(s):  
Carotid Artery ◽  
Shear Force ◽  
Statistical Significance ◽  
Circulatory System ◽  
Repeated Measure ◽  
Control Treatment ◽  
Isotonic Solution ◽  
Internal Temperature ◽  
Post Harvest ◽  
Postmortem Aging

ObjectivesWhole muscle cuts from cows are often less tender than cuts from young fed beef due to increased collagen cross-linking associated with animal age. The injection of a rinse solution through the carotid artery following exsanguination has been shown to improve tenderness. The objective of this study was to compare the effect of a post-harvest rinse of an isotonic solution through the circulatory system on tenderness of steaks from cows.Materials and MethodsCows (n = 28) were randomly assigned to carcass treatments. The carcass treatments consisted of non-rinsed control (n = 14) and a rinsed (n = 14) treatment, where a chilled isotonic solution (MPSC, Inc., St. Paul, MN) was rinsed through the carotid artery and veins following exsanguination. The isotonic solution consisted of water, glucose, maltose and phosphates. Both control and rinsed treatments were electrically stimulated. At 2 d postmortem, strip loins were removed from one side of each carcass. Strip loins were fabricated into 2.54 cm steaks at 3 d postmortem and objective color measurements (L*, a* and b*) were recorded on a single steak after a 30-min bloom period. Steaks were vacuum packaged and aged at 4°C for 7, 14, and 21 d. Following aging, steaks were frozen (–20°C) for future analysis. Warner-Bratzler Shear Force (WBSF) was used to measure tenderness. Frozen steaks were thawed at 4°C for 24 h before cooking. Internal temperature was monitored on all steaks using a digital thermometer that was placed in the center of each steak. Steaks were cooked on an electric clamshell grill to an internal temperature of 71°C. Peak cook temperature was recorded for each steak. Following cooking, steaks were cooled at 4°C and allowed to equilibrate to room temperature (20°C). Six cores (1.27 cm) were removed from each steak and sheared perpendicular to the muscle fiber orientation. The peak force was recorded for each core and the average calculated for each steak. Data were analyzed using the MIXED procedure of SAS (SAS Inst. Inc., Cary, NC). Shear force data were analyzed as a repeated measure with time and treatment as fixed variables. Color data were analyzed as a completely randomized design using treatment as the fixed variable. Statistical significance was considered at an α of P < 0.05 and trends at 0.05 ≤ P < 0.10.ResultsThere was no interaction (P = 0.6068) between treatment and postmortem aging day. Steaks from the rinsed treatment were more tender (P = 0.0005), than steaks in the control treatment (3.51 ± 0.168 kg vs. 4.41 ± 0.174 kg, respectively). Postmortem aging influenced (P = 0.0310) tenderness. Steaks aged 7 d were less tender (P = 0.0087) than steaks aged for 21 d (4.18 ± 0.155 kg vs. 3.72 ± 0.156 kg, respectively), while 14 d steaks did not differ (P > 0.05) from those aged 7 or 21 d. Objective color was not impacted by rinse treatment (P > 0.05).ConclusionThese data suggest that the application of a post-harvest rinse with an isotonic solution through the circulatory system improves the tenderness of cow steaks but does not influence objective color.

scholarly journals Influence of Postmortem Aging and Storage Conditions on Tenderness of Grain and Grass Finished Bison Striploin Steaks

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
J. K. Janssen ◽  
K. M. Cammack ◽  
J. K. Grubbs ◽  
K. R. Underwood ◽  
J. Hansen ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Shear Force ◽  
Frozen Storage ◽  
Covariance Structure ◽  
Storage Conditions ◽  
Meat Tenderness ◽  
Internal Temperature ◽  
Postmortem Aging ◽  
Average Shear ◽  
Force Data

ObjectivesThe objectives of this study were to: 1) compare the influence of postmortem aging on tenderness of striploin steaks from grain- and grass-finished bison, and 2) compare the influence of freezing on tenderness of striploin steaks from grain- and grass-finished bison.Materials and MethodsBison heifers were randomly assigned to finishing treatments: Grain-finished (n = 30, backgrounded on pasture and finished for 130 d with ad libitum access to grass hay, alfalfa and a corn and dry distiller’s grain concentrate prior to slaughter) or Grass-finished (n = 30, remained on pasture until slaughter). Heifers were slaughtered at approximately 28 mo of age, and striploins were removed from both sides of the carcass posterior to the 12th rib separation and fabricated into 2.54-cm steaks. One steak was removed from each striploin (n = 60), vacuum packaged and stored fresh for 14 d at 4°C. Four additional steaks were fabricated from each striploin, aged for 4,7,14, or 21 d, vacuum packaged, and frozen for approximately 3 mo. Warner-Bratzler Shear Force (WBSF) was utilized to determine objective tenderness. Frozen steaks were thawed at 4°C for 24 h before cooking. All steaks were weighed prior to cooking to an internal temperature of 71°C. Internal temperature was monitored using a digital thermometer placed near the geometric center of each steak. After cooking, all steaks were reweighed to determine cook loss and cooled to room temperature (20°C). Five to six 1.27-cm cores were removed from each steak and sheared once perpendicular to the muscle fiber orientation and peak force was recorded. A texture analyzer with a Warner-Bratzler attachment was used to assess instrumental tenderness. An average shear force value was then calculated for each steak. For Objective 1, cook loss and shear force data were analyzed as repeated measures using the ante-dependence covariance structure in the MIXED procedure of SAS (SAS Inst. Inc., Cary, NC) for effects of finishing treatment, aging, and their interaction; peak temperature was included as a covariate. For Objective 2, shear force data were analyzed for the effects of finishing treatment, storage treatment and their interaction using the GLM procedure of SAS. For both objectives, the interaction was not significant and omitted from the final model. Separation of least-squares main effect means was performed using LSD with a Tukey’s adjustment and assuming a level of 0.05.ResultsSteaks from grain finished bison heifers had tendency to be more tender (P = 0.0552) and had less cook loss (P < 0.0001) than steaks from grass finished heifers. Tenderness of all steaks improved (P < 0.0001) with postmortem aging. Aging time also influenced cook loss (P = 0.0199). Cook loss was greater (P = 0.0133) at Day 4 than Day 7 and tended to be greater (P = 0.0561) at Day 4 than Day 21. Frozen storage improved tenderness (P < 0.0001) and increased cook loss (P < 0.0001) of bison steaks compared to fresh storage.ConclusionCollectively this data indicates postmortem aging, storage conditions, and finishing systems influence meat tenderness of bison striploin steaks. Grain-finishing resulted in reduced cook loss and tended to improved tenderness of bison steaks compared to grass-finishing. Additionally, holding bison steaks in frozen storage improved tenderness, but also increased cook loss.

Different Carotenoid Enrichment in Two Climacteric Fruits after Post- Harvest UV-B Treatment

2020 ◽  
Vol 16 (2) ◽  
pp. 102-108
Author(s):  
Carolina F. Assumpção ◽  
Médelin M. da Silva ◽  
Vanessa S. Hermes ◽  
Annamaria Ranieri ◽  
Ester A. Ferreira ◽  
...  
Keyword(s):  
Bioactive Compound ◽  
Ultraviolet B ◽  
Low Flow ◽  
Control Treatment ◽  
Carotenoid Content ◽  
Post Harvest ◽  
Beneficial Effects ◽  
Fruit Skin ◽  
Compound Synthesis ◽  
Viable Method

Background: Ultraviolet B (UV-B) radiation is a promising and environmentally friendly technique, which in a low flow rate, can induce bioactive compound synthesis. This work aimed at evaluating the effectiveness of post-harvest UV-B treatment in order to improve carotenoid content in climacteric fruits like persimmon and guava fruits. Methods: The fruits were harvested at commercial maturity and placed into climatic chambers equipped with UV-B lamps. For control treatment, the UV-B lamps were covered by a benzophenone film, known to block the radiation. This radiation was applied during 48 hours and fruits were sampled at 25, 30 and 48 hours of each treatment. HPLC analysis was performed to separate and identify carotenoid compounds from fruit skin after a saponification process. Results: Fruit from 30 hours treatment began to present a carotenoid accumulation since the majority of analyzed compounds exhibited its synthesis stimulated from this time on. In persimmon skin, it was observed that the maximum content was reached after 48 hours of UV-B treatment. Conclusion: These results suggest that this post-harvest UV-B treatment can be an innovative and a viable method to induce beneficial effects on guava and mainly on persimmon fruit.

Do longitudinal orthodontic trials use appropriate statistical analyses? A meta-epidemiological study

2021 ◽  
Author(s):  
Samer Mheissen ◽  
Haris Khan ◽  
Mohammed Almuzian ◽  
Emad Eddin Alzoubi ◽  
Nikolaos Pandis
Keyword(s):  
Statistical Analysis ◽  
Epidemiological Study ◽  
Data Extraction ◽  
Statistical Significance ◽  
Repeated Measure ◽  
Exact Test ◽  
Optimal Analysis ◽  
Study Characteristics ◽  
Measure Analysis ◽  
Repeated Measure Analysis

Summary Background In orthodontic trials, longitudinal designs with multiple outcome measurements over time are common. The aim of this epidemiological study was to examine whether optimal statistical analysis approaches have been used in longitudinal orthodontic trials. Methods Pubmed was searched in August 2021 for longitudinal orthodontic trials with at least three time points of outcome assessment published in the 2017–20 period. Study selection and data extraction were done independently and in duplicate. The analysis approaches undertaken were tabulated and associations between study characteristics and the use of optimal analysis or not were assessed using Fisher’s exact test and logistic regression. Results One hundred forty-seven out of 563 unique records were deemed eligible for inclusion. Only 26.50% of these trials used an optimal statistical analysis for longitudinal data where the data structure is accounted for. None of the study characteristics except the statistical significance of the results were associated with the appropriateness of the statistical analysis. The odds of significant results in studies with suboptimal analyses were higher than that in studies with optimal longitudinal analyses (odds ratio: 3.48, 95% confidence interval: 1.62, 7.46, P = 0.001). For the studies with optimal analysis, the most frequent test was repeated-measure analysis of variance (RM-ANOVA). The reporting of the statistical analysis section was suboptimal in the majority of the trials. Conclusion Most longitudinal orthodontic trials are not analysed using optimal statistical approaches. Inferences and interpretation of their results are likely to be compromised.

scholarly journals Assessment of Postmortem Aging Effects on Texas-style Barbecue Beef Briskets

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
McKensie K. Harris ◽  
Ray R. Riley ◽  
Ashley N. Arnold ◽  
Rhonda K. Miller ◽  
Davey B. Griffin ◽  
...  
Keyword(s):  
Force Measurements ◽  
Internal Temperature ◽  
Aging Effects ◽  
Oak Wood ◽  
Long Period ◽  
Aging Period ◽  
Postmortem Aging ◽  
Salt And Pepper

Palatability traits (tenderness, juiciness, flavor, and overall liking) of beef briskets (n = 48) were evaluated for 3 different postmortem aging period comparisons: 7 d vs. 21 d (Set 1), 21 d vs. 35 d (Set 2), and 7 d vs. 35 d (Set 3). Briskets were prepared as Texas-style barbecue by seasoning with salt and pepper and smoking with oak wood over a long period (approx. 11 h) using a commercial oven designed for such purposes until deemed tender (approx. 85°C internal temperature). Within each treatment set, Warner-Bratzler shear (WBS) force measurements did not differ (P > 0.05) between aging days; however, WBS force measurements for point (Mm. pectorales superficiales composed of the M. pectoralis transversus and M. pectoralis descendens) were lower (P < 0.05) compared to the flat portions (M. pectorals profundus) within each aging set. Consumer panelists did not (P > 0.05) detect differences between aging days within each set for overall liking, flavor liking, tenderness liking, and juiciness liking. Conversely, differences were found between brisket point and flat portions; Set 1 differed for flavor liking (flat > point; P = 0.0348) and juiciness liking (point > flat; P = 0.0004), Set 2 differed for overall liking (flat > point; P = 0.0499) and juiciness liking (point > flat; P < 0.0001), and Set 3 differed for overall liking (flat > point; P = 0.0296) and juiciness liking (point > flat; P = 0.0112). Our findings indicate postmortem aging did not improve beef brisket palatability, but we did note differences between point and flat portions. Preparing beef briskets as Texas-style barbecue resulted in products with low WBS values and high consumer palatability ratings, which helps demonstrate why barbecued briskets are so popular.

The Comparison of STA-MCA Bypass and BMT for Symptomatic Internal Carotid Artery Occlusion Disease A Systematic Review and Meta-analysis of Long-term Outcome

2020 ◽  
Author(s):  
Xinyu Yang ◽  
Shifei Cai ◽  
Hao Fan ◽  
Chao Peng ◽  
Yuzhang Wu
Keyword(s):  
Carotid Artery ◽  
Assessment Tool ◽  
Statistical Significance ◽  
Superficial Temporal Artery ◽  
Artery Occlusion ◽  
Carotid Artery Occlusion ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Symptomatic Carotid

Abstract Background: Superficial temporal artery (STA) - middle cerebral artery (MCA) bypass surgery now being widely used in moyamoya disease, and its therapeutic value in SICAO remains divergent. Methods: A systematic search was performed in PUBMED, EMBASE and Cochrane Databases in Feb.2020, and updated in Jun.2019. We have strict inclusion and exclusion criteria. Cochrane Bias Risk Assessment Tool was used to assess the quality of included RCTs. Review Manager 5.3 was used for analysis results in terms of comparing the STA-MCA bypass and BMT. For dichotomous variable outcomes, Risk Ratio (RRs) and 95% confidence intervals (95%CIs) were calculated for the assessment.Results: The total patient cohort consisted of 2419 patients, of whom 1188(49.1%) patients had been grouped in STA-MCA bypass, 1231(50.9%) patients had divided into BMT group. Mean follow-up of including patients was 29 months. The RRs of the seven studies was 1.01, and the 95% confidence interval was .89-1.15, with statistical significance, Z=.13, P=.89, sustaining that STA-MCA bypass was not superior to BMT in symptomatic carotid artery occlusion disease.Conclusion: STA-MCA bypass and BMT were associated with similar rates of a composite of long-term stroke. And the risk of long-term overall stroke was mildly higher with BMT. At present, each patient should receive more precise treatment, by reasonably assess the individual differences of each patient to reduce the recurrence rate of stroke.

scholarly journals 54 Digestibility of forages in ruminally cannulated Jersey steers supplemented with liquid glycerol on a wheat straw forage diet

2019 ◽  
Vol 97 (Supplement_1) ◽  
pp. 84-84
Author(s):  
Itzel A Soto ◽  
Jamie Boyd
Keyword(s):  
Statistical Significance ◽  
Latin Square ◽  
Test Period ◽  
Control Treatment ◽  
Treatment Control ◽  
Forage Digestibility ◽  
Significant Difference ◽  
Glycerol Treatment ◽  
The Impact

Abstract The purpose of this study was to determine the impact of supplementation of glycerol at a rate of 15% of DMI on forage digestibility on a diet of mature wheat hay. Forages tested included bermuda hay, wheat hay, alfalfa hay, and sorghum sudan hay. Samples were ground through a 2mm screen and placed in Ankom forage in-situ bags. Samples were run in triplicate to reduce error and increase statistical significance. Two ruminally cannulated steers were used in a 2x2 Latin square design for the study with ad libitum access to wheat hay and water. Animals were housed in a dry lot pen for the study. Diets offered were Control = wheat hay and Treatment= control + glycerol at 15% of daily DMI. The study consisted of 2 three-week periods. Each period had a 2-week standardization followed by a 1-week test period. During the test period, forage bags were placed in each steer for 0 h, 48 h, 72 h, 96 h, and 144 h for fermentation. At the end of the incubation period, bags were collected and cold shocked to stop microbial digestion. The samples were then dried at 55°C and stored for later analysis for NDF. A significant impact on NDFdig by treatment (P < 0.0001) was observed. NDFdig was 59.2% w/ glycerol versus control at 49.13% overall. In addition, there was a significant difference between steers (P = 0.0001) on glycerol treatment (51.95% versus 66.45% NDFdig between steer A and B), indicating difference in ruminal population efficiency between individual animals. No significant difference (P = 0.98) between steers on the control treatment was observed. Implications of this study are the inclusion of dietary glycerol in the diet of ruminants on a low-quality forage diet may increase energy level and improve ruminal digestibility and animal response may be dependent on the unique ruminal environment of individual animals.

scholarly journals 145 Digestibility of forages in ruminally cannulated Jersey steers supplemented with liquid glycerol on a wheat straw forage diet

2019 ◽  
Vol 97 (Supplement_1) ◽  
pp. 37-37
Author(s):  
Itzel A Soto ◽  
Jamie Boyd
Keyword(s):  
Statistical Significance ◽  
Latin Square ◽  
Test Period ◽  
Control Treatment ◽  
Treatment Control ◽  
Forage Digestibility ◽  
Significant Difference ◽  
Glycerol Treatment ◽  
The Impact

Abstract The purpose of this study was to determine the impact of supplementation of glycerol at a rate of 15% of DMI on forage digestibility on a diet of mature wheat hay. Forages tested included bermuda hay, wheat hay, alfalfa hay, and sorghum sudan hay. Samples were ground through a 2mm screen and placed in Ankom forage in-situ bags. Samples were run in triplicate to reduce error and increase statistical significance. Two ruminally cannulated steers were used in a 2x2 Latin square design for the study with ad libitum access to wheat hay and water. Animals were housed in a dry lot pen for the study. Diets offered were Control = wheat hay and Treatment= control + glycerol at 15% of daily DMI. The study consisted of 2 three-week periods. Each period had a 2-week standardization followed by a 1-week test period. During the test period, forage bags were placed in each steer for 0 h, 48 h, 72 h, 96 h, and 144 h for fermentation. At the end of the incubation period, bags were collected and cold shocked to stop microbial digestion. The samples were then dried at 55°C and stored for later analysis for NDF. A significant impact on NDFdig by treatment (P < 0.0001) was observed. NDFdig was 59.2% w/ glycerol versus control at 49.13% overall. In addition, there was a significant difference between steers (P = 0.0001) on glycerol treatment (51.95% versus 66.45% NDFdig between steer A and B), indicating difference in ruminal population efficiency between individual animals. No significant difference (P = 0.98) between steers on the control treatment was observed. Implications of this study are the inclusion of dietary glycerol in the diet of ruminants on a low-quality forage diet may increase energy level and improve ruminal digestibility and animal response may be dependent on the unique ruminal environment of individual animals.

scholarly journals 83 Tenderness and cooking loss of beef loins

2019 ◽  
Vol 97 (Supplement_1) ◽  
pp. 27-28 ◽  
Author(s):  
Robin G Coombs ◽  
C R Richardon
Keyword(s):  
Standard Deviation ◽  
Meat Quality ◽  
Shear Force ◽  
Quality Attributes ◽  
Grocery Store ◽  
Cooking Loss ◽  
Longissimus Muscle ◽  
Internal Temperature ◽  
Regional Area ◽  
Resting Period

Abstract The focus of this study involved measuring two variables of meat quality: tenderness and cooking loss. Experiments were conducted on a premium cut of meat – the loin. The loin contains the Longissimus muscle, with pieces of the Iliocostalis and Spinalis dorsi muscles. The Longissimus muscle was cored for tenderness. Two sources of loins were evaluated: Akaushi breed, and from a commercial grocery store. Meat used consisted of Akaushi loins from 6 different animals (prime grade) and one select grade loin (control). The protocol involved dividing each loin into 6 (907-1134g) roasts, cooking at 104.40 C (to internal temperature of 73.90 C), measuring by weight the cooking loss of the roasts after a 30-minute resting period, and determining tenderness by Warner-Bratzler Shear Force (WBSF) (after overnight storage in a cooler). Cores were taken at 6 different locations of the roast, over the same regional area for WBSF determinations. The WBSF coring instrument used was provided. Tenderness of each loin was measured in 36 cores (n = 36). In overall tenderness, the control loin ranked third out of the seven loins and had the least amount of cooking loss. No differences were found in tenderness (P > 0.05). However, a difference was found in average cooking loss 181.44g ± 0.03 (control); 254.01g ± 0.03 (Akaushi) (P < 0.05). When observing tenderness consistency, the control loin had a somewhat larger standard deviation (1.38 vs 0.756) than the Akaushi loins.Loins used in this study showed variation in cooking loss, tenderness, and consistency between a commercial grocery store source and the Akaushi beef source. These data indicates that quality attributes of beef loins used in this study may be different in ways not related to grade.

scholarly journals Simulation Study of Distal Balloon Protection Systems during Carotid Artery Stenting

2004 ◽  
Vol 10 (2_suppl) ◽  
pp. 79-84
Author(s):  
T. Kuroiwa ◽  
N. Sakai ◽  
M. Sakaguchi ◽  
H. Adachi ◽  
H. Imamura ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Internal Carotid ◽  
Circulatory System ◽  
Optimal Placement ◽  
Simulation Studies ◽  
Distal Embolization ◽  
Simulation Experiments ◽  
Protection Systems ◽  
Particulate Debris ◽  
Balloon Protection

The purpose of our experimental study was to assess the pitfalls of distal balloon protection systems and to learn any technique tips to increase safety. Silicone carotid artery models were connected to a circulatory system to simulate arterial flow. A distal balloon protection device, PercuSurge GuardWire Plus (GWP, Medtronic Vascular) was delivered to the internal carotid artery (ICA), then was inflated to occlude ICA flow temporarily. A debris aspiration catheter (Export catheter) was delivered just proximal to the GuardWire Plus balloon coaxially, in order to introduce and diffuse particulate debris (200–500 micro meter in diameter) in the ICA stump. Then, after debris in the stump was aspirated, the GWP balloon was deflated. We recorded all the processes of our simulation experiments on a digital video and observed the movements of debris during these experiments. Exp 1) We simulated the movements of debris in the ICA stump when the GWP balloon was gradually deflated to produce a crevice between the balloon and vessel wall, simulating accidental movement of the GWP balloon during the procedure. Exp 2) In order to assess the optimal placement of the tip of aspiration catheter, the debris in the ICA stump was aspirated from three different sites (from just below the GuardWire balloon, from 2 cm below it, and from 5 cm below it). Exp 1) When the crevice appeared between GuardWire balloon and silicone tube, simulated debris began to concentrate just below the balloon. Then, some debris migrated distally from the crevice, and another part crowded in the crevice so that was impossible to aspirate and migrated in the end. Exp. 2) Debris aspiration was most effective from immediately below the GuardWire balloon, and the aspiration ability declined as the distance between the balloon and aspiration catheter became longer. According to our simulation studies, when the GWP balloon was moved accidentally during CAS procedures, or when the aspiration catheter was not delivered all the way to the GuardWire Plus balloon, distal embolization might still occur, even under protection.

Carotid artery webs in embolic stroke of undetermined source with large intracranial vessel occlusion

2020 ◽  
pp. 174749302092994
Author(s):  
Marc-Antoine Labeyrie ◽  
Fabiola Serrano ◽  
Vittorio Civelli ◽  
Clément Jourdaine ◽  
Peggy Reiner ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Carotid Artery ◽  
Confidence Interval ◽  
Statistical Significance ◽  
Embolic Stroke ◽  
Wall Thickening ◽  
Intracranial Artery ◽  
Vessel Occlusion ◽  
Potential Source ◽  
Artery Embolism

Background Whether carotid artery web can be considered as a potential source of arterial thromboembolism in ischemic stroke remains uncertain. Aims In a large sample of individuals with large intracranial artery occlusion, we compared the prevalence of carotid artery webs between patients with and without embolic stroke of undetermined source. Methods In a single-center study of consecutive patients with anterior circulation ischemic stroke referred for mechanical thrombectomy, the presence of carotid artery web was systematically assessed by two independent readers. Thereafter, its prevalence was compared between patients with and without embolic stroke of undetermined source. Results Among 466 patients of whom 12% were considered to have had an embolic stroke of undetermined source, ipsilateral carotid artery web was detected in 1.9% (confidence interval 95% = 0.7–3.1). Ipsilateral carotid artery web was more frequent in embolic stroke of undetermined source than in the rest of the sample (10.7% (confidence interval 95% = 2.7–18.7] vs. 0.7% (0–1.5), P < 0.001). This difference remains significant after adjustment for sex, age, and vascular risk factor (odds ratio: 12.5 (2.1–72), P = 0.005) or after exclusion of patients with any other bulb wall thickening ( P = 0.025). In contrast, the difference of prevalence of contralateral carotid artery web between the two groups did not reach statistical significance (2.4% vs. 1.9%, P = 0.6). Conclusions Our results suggest that the presence of a carotid artery web might be considered as a potential source of large intracranial artery embolism. Longitudinal studies are needed to assess the exact risk of recurrence associated with these lesions.

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