Personalized medicine: a competitor or an upgrade of evidence-based medicine?

2012 ◽  
Vol 9 (2) ◽  
pp. 211-221 ◽  
Author(s):  
Daniel Bereczki
Keyword(s):  
Personalized Medicine ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
Based Medicine

scholarly journals Mental disorders of known aetiology and precision medicine in psychiatry: a promising but neglected alliance

2016 ◽  
Vol 47 (2) ◽  
pp. 193-197 ◽  
Author(s):  
D. Fraguas ◽  
C. M. Díaz-Caneja ◽  
M. W. State ◽  
M. C. O'Donovan ◽  
R. E. Gur ◽  
...  
Keyword(s):  
Personalized Medicine ◽  
Mental Disorders ◽  
Precision Medicine ◽  
Psychiatric Disorders ◽  
Evidence Based Medicine ◽  
Prediction Models ◽  
Deletion Syndrome ◽  
Clinical Approach ◽  
Evidence Based ◽  
Based Medicine

Personalized or precision medicine is predicated on the assumption that the average response to treatment is not necessarily representative of the response of each individual. A commitment to personalized medicine demands an effort to bring evidence-based medicine and personalized medicine closer together. The use of relatively homogeneous groups, defined using a priori criteria, may constitute a promising initial step for developing more accurate risk-prediction models with which to advance the development of personalized evidence-based medicine approaches to heterogeneous syndromes such as schizophrenia. However, this can lead to a paradoxical situation in the field of psychiatry. Since there has been a tendency to loosely define psychiatric disorders as ones without a known aetiology, the discovery of an aetiology for psychiatric syndromes (e.g. 22q11.2 deletion syndrome in some cases of schizophrenia), while offering a path toward more precise treatments, may also lead to their reclassification away from psychiatry. We contend that psychiatric disorders with a known aetiology should not be removed from the field of psychiatry. This knowledge should be used instead to guide treatment, inasmuch as psychotherapies, pharmacotherapies and other treatments can all be valid approaches to mental disorders. The translation of the personalized clinical approach inherent to psychiatry into evidence-based precision medicine can lead to the development of novel treatment options for mental disorders and improve outcomes.

Personalized medicine is the evidence based medicine saved in the right horizon

2015 ◽  
Vol 13 (2) ◽  
pp. 91-95
Author(s):  
Antonio del Puente ◽  
Vinicio Lombardi ◽  
Antonella Esposito
Keyword(s):  
Personalized Medicine ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
The Right ◽  
Based Medicine

scholarly journals From evidence-based medicine to personalized medicine, with particular emphasis on drug-safety monitoring

2017 ◽  
Vol 110 (6-7) ◽  
pp. 413-419 ◽  
Author(s):  
Pierre-Vladimir Ennezat ◽  
Shona Cosgrove ◽  
Hélène Bouvaist ◽  
Sylvestre Maréchaux ◽  
Raphaëlle-Ashley Guerbaai ◽  
...  
Keyword(s):  
Personalized Medicine ◽  
Drug Safety ◽  
Evidence Based Medicine ◽  
Safety Monitoring ◽  
Evidence Based ◽  
Drug Safety Monitoring ◽  
Based Medicine
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