Injectable extended-release naltrexone for the prevention of relapse to opioid dependence following opioid detoxification

2012 ◽  
Vol 2 (4) ◽  
pp. 355-362
Author(s):  
Evgeny Krupitsky
Keyword(s):  
Opioid Dependence ◽  
Extended Release ◽  
Prevention Of Relapse ◽  
Opioid Detoxification

The Stress Respond, Related To the Opioid Abstinence And Detoxification: literature review

2014 ◽  
Vol 21 (1) ◽  
pp. 86-90
Author(s):  
Robertas Badaras ◽  
Gabija Dragelytė ◽  
Indrė Vaitekonytė ◽  
Juozas Ivaškevičius ◽  
Jūratė Šipylaitė
Keyword(s):  
Opioid Dependence ◽  
Financial Resources ◽  
Successful Completion ◽  
Minimum Risk ◽  
Medical Databases ◽  
Dosing Regimens ◽  
Naltrexone Treatment ◽  
Dopaminergic Pathways ◽  
Pituitary Adrenal Axis ◽  
Opioid Detoxification

Materials and Methods. Published articles on the opioid abuse and methods of opioid detoxification were identified by searching medical databases, using corresponding literature and were also searched manually for applicable papers. The search was limited to articles published from 1985 through 2014. Results. Opioid dependence determine pathophysiologic changes in the dopaminergic pathways of the organism, as well as the alterations in the stress-responsive hypothalamic-pituitary-adrenal axis. The usage of opioid antagonists in the early stages of withdrawal, can lead the effectiveness of opioid detoxification to 100%. Rapid opioid detoxification do not remove all the symptoms of abstinence. Negative aspects, concerning the procedure, while using prevention, can be reduced to the minimum risk. Rapid opioid detoxification, comparing it with Ultrarapid opioid detoxification procedure, diverges as less financial resources and a lower risk containing technique. Conclusions. Use of antagonists may reduce the duration of withdrawal, thus reducing the overall severity of withdrawal and increasing the chances of successful completion. This technique facilitates commencement of naltrexone treatment. Dosing regimens used in clinical trials vary. Subsequent results do not correlate with the methods of detoxification.

scholarly journals Effectiveness of Injectable Extended-Release Naltrexone vs Daily Buprenorphine-Naloxone for Opioid Dependence

2017 ◽  
Vol 74 (12) ◽  
pp. 1197 ◽  
Author(s):  
Lars Tanum ◽  
Kristin Klemmetsby Solli ◽  
Zill-e-Huma Latif ◽  
Jurate Šaltyte Benth ◽  
Arild Opheim ◽  
...  
Keyword(s):  
Opioid Dependence ◽  
Extended Release

Workforce attitudes regarding the implementation of extended release naltrexone to treat opioid dependence

2015 ◽  
Vol 146 ◽  
pp. e209
Author(s):  
Laura Andrich ◽  
Katherine T. Garvey ◽  
Elias M. Klemperer ◽  
Traci R. Rieckmann
Keyword(s):  
Opioid Dependence ◽  
Extended Release

Injectable extended-release naltrexone for opioid dependence

The Lancet ◽  
2011 ◽  
Vol 378 (9792) ◽  
pp. 665-666 ◽  
Author(s):  
Douglas C Throckmorton ◽  
Robert Temple ◽  
Bob A Rappaport ◽  
Rigoberto Roca ◽  
Celia J Winchell
Keyword(s):  
Opioid Dependence ◽  
Extended Release

Healthcare utilization in adults with opioid dependence receiving extended release naltrexone compared to treatment as usual

2018 ◽  
Vol 85 ◽  
pp. 66-69 ◽  
Author(s):  
William E. Soares ◽  
Donna Wilson ◽  
Niels Rathlev ◽  
Joshua D. Lee ◽  
Michael Gordon ◽  
...  
Keyword(s):  
Healthcare Utilization ◽  
Opioid Dependence ◽  
Extended Release ◽  
Treatment As Usual

S273. The Effectiveness of Injectable Extended Release Naltrexone Versus Daily Buprenorphine-Naloxone for Opioid Dependence in Short and Long Term Treatment

2018 ◽  
Vol 83 (9) ◽  
pp. S454 ◽  
Author(s):  
Lars Tanum ◽  
Kristin Solli ◽  
Zill-E-Huma Latif ◽  
Jūratė Šaltytė Benth ◽  
Arild Opheim ◽  
...  
Keyword(s):  
Opioid Dependence ◽  
Extended Release ◽  
Term Treatment ◽  
Long Term Treatment ◽  
Short And Long Term
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