Recent advances in liposome surface modification for oral drug delivery

Nanomedicine ◽  
2016 ◽  
Vol 11 (9) ◽  
pp. 1169-1185 ◽  
Author(s):  
Thanh Xuan Nguyen ◽  
Lin Huang ◽  
Mario Gauthier ◽  
Guang Yang ◽  
Qun Wang
Keyword(s):  
Drug Delivery ◽  
Surface Modification ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Recent Advances ◽  
Liposome Surface

Effects of surface modification and size on oral drug delivery of mesoporous silica formulation

2018 ◽  
Vol 513 ◽  
pp. 736-747 ◽  
Author(s):  
Ying Wang ◽  
Yu Cui ◽  
Yating Zhao ◽  
Qinfu Zhao ◽  
Bing He ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Surface Modification ◽  
Mesoporous Silica ◽  
Oral Drug Delivery ◽  
Oral Drug

Recent Advances in Pelletization Technique for Oral Drug Delivery: A Review

2009 ◽  
Vol 6 (1) ◽  
pp. 122-129 ◽  
Author(s):  
Md. Akhlaquer Rahman ◽  
Alka Ahuja ◽  
S. Baboota ◽  
Bhavna ◽  
Vikas Bali ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Recent Advances

scholarly journals Recent Advances in Microneedle Platforms for Transdermal Drug Delivery Technologies

Polymers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 2405
Author(s):  
Sipho Mdanda ◽  
Philemon Ubanako ◽  
Pierre P. D. Kondiah ◽  
Pradeep Kumar ◽  
Yahya E. Choonara
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Oral Drug Delivery ◽  
Clinical Applications ◽  
Oral Drug ◽  
Scientific Curiosity ◽  
Recent Advances ◽  
Alternative Approach ◽  
Microneedle Arrays ◽  
Transdermal Route

In many clinical applications, the transdermal route is used as an alternative approach to avoid the significant limitations associated with oral drug delivery. There is a long history for drug delivery through the skin utilizing transdermal microneedle arrays. Microneedles are reported to be versatile and very efficient devices. This technique has spurred both industrial and scientific curiosity, due to its outstanding characteristics such as painless penetration, affordability, excellent medicinal efficiency, and relative protection. Microneedles possess outstanding properties for diverse biomedical uses such as the delivery of very large substances with ionic and hydrophilic physicochemical properties. Importantly, microneedles are applicable in numerous biomedical fields such as therapy, diagnosis, and vaccine administration. Microneedles are emerging tools that have shown profound potential for biomedical applications. Transdermal microneedle technologies are likely to become a preferred route of therapeutic substances administration in the future since they are effective, painless, and affordable. In this review, we summarize recent advances in microneedles for therapeutic applications. We explore their constituent materials and fabrication methods that improve the delivery of critical therapeutic substances through the skin. We further discuss the practicality of advanced microneedles used as drug delivery tools.

Applications of Ion Exchange Resin in Oral Drug Delivery Systems

2017 ◽  
Vol 7 (03) ◽  
Author(s):  
Kathpalia Harsha ◽  
Das Sukanya
Keyword(s):  
Drug Delivery ◽  
Ion Exchange ◽  
Drug Delivery Systems ◽  
Oral Drug Delivery ◽  
Physical Stability ◽  
Delivery Systems ◽  
Oral Drug ◽  
Ion Exchange Resins ◽  
Exchange Resins ◽  
Oral Drug Delivery Systems

Ion Exchange Resins (IER) are insoluble polymers having styrene divinylbenzene copolymer backbone that contain acidic or basic functional groups and have the ability to exchange counter ions with the surrounding aqueous solutions. From the past many years they have been widely used for purification and softening of water and in chromatographic columns, however recently their use in pharmaceutical industry has gained considerable importance. Due to the physical stability and inert nature of the resins, they can be used as a versatile vehicle to design several modified release dosage forms The ionizable drug is complexed with the resin owing to the property of ion exchange. This resin complex dissociatesin vivo to release the drug. Based on the dissociation strength of the drug from the drug resin complex, various release patterns can be achieved. Many formulation glitches can be circumvented using ion exchange resins such as bitter taste and deliquescence. These resins also aid in enhancing disintegrationand stability of formulation. This review focuses on different types of ion exchange resins, their preparation methods, chemistry, properties, incompatibilities and their application in various oral drug delivery systems as well as highlighting their use as therapeutic agents.

Implication of Nanofibers in Oral Drug Delivery

2015 ◽  
Vol 21 (15) ◽  
pp. 2021-2036 ◽  
Author(s):  
Himani Kapahi ◽  
Nikhat Khan ◽  
Ankur Bhardwaj ◽  
Neeraj Mishra
Keyword(s):  
Drug Delivery ◽  
Oral Drug Delivery ◽  
Oral Drug
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