Adoptive immunotherapy with polyclonal T cells and natural killer cells for hematological malignancies: current status and future prospects

2013 ◽  
Vol 2 (4) ◽  
pp. 325-338 ◽  
Author(s):  
Yeh-Ching Linn
Keyword(s):  
T Cells ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Adoptive Immunotherapy ◽  
Hematological Malignancies ◽  
Current Status ◽  
Future Prospects ◽  
Killer Cells

scholarly journals Antibody cooperative adsorption onto AuNPs and its exploitation to force natural killer cells to kill HIV-infected T cells

Nano Today ◽  
2021 ◽  
Vol 36 ◽  
pp. 101056
Author(s):  
Antonio Astorga-Gamaza ◽  
Michele Vitali ◽  
Mireya L. Borrajo ◽  
Rosa Suárez-López ◽  
Carlos Jaime ◽  
...  
Keyword(s):  
T Cells ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Killer Cells ◽  
Cooperative Adsorption

scholarly journals Natural killer cells as a therapeutic tool for infectious diseases - current status and future perspectives

Oncotarget ◽  
2018 ◽  
Vol 9 (29) ◽  
pp. 20891-20907 ◽  
Author(s):  
Stanislaw Schmidt ◽  
Lars Tramsen ◽  
Bushra Rais ◽  
Evelyn Ullrich ◽  
Thomas Lehrnbecher
Keyword(s):  
Natural Killer Cells ◽  
Infectious Diseases ◽  
Natural Killer ◽  
Current Status ◽  
Future Perspectives ◽  
Therapeutic Tool ◽  
Killer Cells

scholarly journals In Vivo Survival and Homeostatic Proliferation of Natural Killer Cells

2003 ◽  
Vol 197 (8) ◽  
pp. 967-976 ◽  
Author(s):  
Martin Prlic ◽  
Bruce R. Blazar ◽  
Michael A. Farrar ◽  
Stephen C. Jameson
Keyword(s):  
T Cells ◽  
Natural Killer Cells ◽  
Nk Cells ◽  
Natural Killer ◽  
Cell Sorting ◽  
Functional Activity ◽  
Homeostatic Proliferation ◽  
Killer Cells ◽  
Bystander Cells

While the specificity and development of natural killer (NK) cells have been intensely studied, little is known about homeostasis of the mature NK population. Here we show that mouse NK cells undergo homeostatic proliferation when transferred into NK-deficient Rag−/− γC−/− hosts. Normal NK functional activity is maintained during this process, although there are some changes in NK phenotype. Using cell sorting, we demonstrate that mature (Mac-1hi) NK cells undergo homeostatic proliferation in an NK-deficient environment, yet immature (Mac-1lo) NK cells also proliferate in such hosts. We find that mature NK cells survive but do not proliferate in hosts which possess an endogenous NK pool. However, we go on to show that mature NK survival is critically dependent on interleukin (IL)-15. Surprisingly, NK survival is also compromised after transfer of cells into IL-15Rα−/− mice, implying that IL-15 responsiveness by bystander cells is critical for NK maintenance. These data imply that, similar to T cells, homeostasis of the NK pool is much more dynamic than previously appreciated and this may be relevant to manipulation of NK cells for therapeutic purposes.

Natural killer cells and natural killer T cells in patients with renal transplantation 1

2008 ◽  
Vol 32 (3) ◽  
pp. -
Author(s):  
Anett Hoppe ◽  
Manja Kamprad ◽  
Claudia Wegmann ◽  
Michael Wötzel ◽  
Johann Hauss ◽  
...  
Keyword(s):  
T Cells ◽  
Renal Transplantation ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Natural Killer T Cells ◽  
Killer Cells ◽  
Killer T Cells ◽  
Natural Killer T
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