Perspectives on surgical management of neuroendocrine liver metastases

2015 ◽  
Vol 2 (1) ◽  
pp. 67-74
Author(s):  
Todd Hore ◽  
Graeme Poston
Keyword(s):  
Liver Metastases ◽  
Surgical Management ◽  
Neuroendocrine Liver Metastases

scholarly journals Additional value of gadoxetic acid-enhanced MRI to conventional extracellular gadolinium-enhanced MRI for the surgical management of colorectal and neuroendocrine liver metastases

HPB ◽  
2020 ◽  
Vol 22 (5) ◽  
pp. 710-715 ◽  
Author(s):  
Claudya Morin ◽  
Sebastien Drolet ◽  
Carl Daigle ◽  
Isabelle Deshaies ◽  
Jean-Francois Ouellet ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Surgical Management ◽  
Gadoxetic Acid ◽  
Enhanced Mri ◽  
Additional Value ◽  
Neuroendocrine Liver Metastases

scholarly journals Surgical management of pancreatic neuroendocrine liver metastases

2020 ◽  
Vol 11 (3) ◽  
pp. 590-600
Author(s):  
Jordan M. Cloyd ◽  
Jason T. Wiseman ◽  
Timothy M. Pawlik
Keyword(s):  
Liver Metastases ◽  
Surgical Management ◽  
Neuroendocrine Liver Metastases

scholarly journals Automatized Hepatic Tumor Volume Analysis of Neuroendocrine Liver Metastases by Gd-EOB MRI—A Deep-Learning Model to Support Multidisciplinary Cancer Conference Decision-Making

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2726
Author(s):  
Uli Fehrenbach ◽  
Siyi Xin ◽  
Alexander Hartenstein ◽  
Timo Alexander Auer ◽  
Franziska Dräger ◽  
...  
Keyword(s):  
Liver Metastases ◽  
External Validation ◽  
High Accuracy ◽  
Hepatic Tumor ◽  
Liver Malignancies ◽  
Internal Validation ◽  
Matthew’S Correlation Coefficient ◽  
Therapy Success ◽  
Neuroendocrine Liver Metastases

Background: Rapid quantification of liver metastasis for diagnosis and follow-up is an unmet medical need in patients with secondary liver malignancies. We present a 3D-quantification model of neuroendocrine liver metastases (NELM) using gadoxetic-acid (Gd-EOB)-enhanced MRI as a useful tool for multidisciplinary cancer conferences (MCC). Methods: Manual 3D-segmentations of NELM and livers (149 patients in 278 Gd-EOB MRI scans) were used to train a neural network (U-Net architecture). Clinical usefulness was evaluated in another 33 patients who were discussed in our MCC and received a Gd-EOB MRI both at baseline and follow-up examination (n = 66) over 12 months. Model measurements (NELM volume; hepatic tumor load (HTL)) with corresponding absolute (ΔabsNELM; ΔabsHTL) and relative changes (ΔrelNELM; ΔrelHTL) between baseline and follow-up were compared to MCC decisions (therapy success/failure). Results: Internal validation of the model’s accuracy showed a high overlap for NELM and livers (Matthew’s correlation coefficient (φ): 0.76/0.95, respectively) with higher φ in larger NELM volume (φ = 0.80 vs. 0.71; p = 0.003). External validation confirmed the high accuracy for NELM (φ = 0.86) and livers (φ = 0.96). MCC decisions were significantly differentiated by all response variables (ΔabsNELM; ΔabsHTL; ΔrelNELM; ΔrelHTL) (p < 0.001). ΔrelNELM and ΔrelHTL showed optimal discrimination between therapy success or failure (AUC: 1.000; p < 0.001). Conclusion: The model shows high accuracy in 3D-quantification of NELM and HTL in Gd-EOB-MRI. The model’s measurements correlated well with MCC’s evaluation of therapeutic response.

scholarly journals Erratum to: Chemoembolization of Neuroendocrine Liver Metastases Using Streptozocin and Tris-acryl Microspheres: Embozar (EMBOsphere + ZAnosaR) Study

2017 ◽  
Vol 40 (3) ◽  
pp. 480-480 ◽  
Author(s):  
Jean-Pierre Pelage ◽  
Audrey Fohlen ◽  
Emmanuel Mitry ◽  
Christine Lagrange ◽  
Alain Beauchet ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Neuroendocrine Liver Metastases

scholarly journals Hepatic Resection for Neuroendocrine Liver Metastases: Contemporary Indications and Outcomes from a Population-Based Cohort

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S113
Author(s):  
S. Scoville ◽  
D. Xourafas ◽  
A. Ejaz ◽  
M. Dillhoff ◽  
A. Tsung ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Hepatic Resection ◽  
Population Based ◽  
Neuroendocrine Liver Metastases

scholarly journals Surgical management and outcomes of colorectal cancer liver metastases

2010 ◽  
Vol 97 (7) ◽  
pp. 1110-1118 ◽  
Author(s):  
E. J. A. Morris ◽  
D. Forman ◽  
J. D. Thomas ◽  
P. Quirke ◽  
E. F. Taylor ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastases ◽  
Surgical Management ◽  
Colorectal Cancer Liver Metastases

Cryotherapy for neuroendocrine liver metastases

1998 ◽  
Vol 14 (2) ◽  
pp. 175-183 ◽  
Author(s):  
Joachim K. Seifert ◽  
Paul J. Cozzi ◽  
David L. Morris
Keyword(s):  
Liver Metastases ◽  
Neuroendocrine Liver Metastases
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