Proteomics-related biomarkers for HBV-associated hepatocellular carcinoma: current status and future prospects

2012 ◽  
Vol 7 (2) ◽  
pp. 161-171
Author(s):  
Huixing Feng ◽  
Jianhua Zhang ◽  
Jane YL Tan ◽  
Laleh Sadrolodabaee ◽  
Wei Ning Chen
Keyword(s):  
Hepatocellular Carcinoma ◽  
Current Status ◽  
Future Prospects

scholarly journals Positron-emission tomography for hepatocellular carcinoma: Current status and future prospects

2019 ◽  
Vol 25 (32) ◽  
pp. 4682-4695 ◽  
Author(s):  
Ren-Cai Lu ◽  
Bo She ◽  
Wen-Tao Gao ◽  
Yun-Hai Ji ◽  
Dong-Dong Xu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Current Status ◽  
Future Prospects ◽  
Positron Emission

scholarly journals Current Status and Future Prospects of Biomarkers in the Diagnosis of Hepatocellular Carcinoma

2017 ◽  
Vol 32 (4) ◽  
pp. 361-369 ◽  
Author(s):  
Yunsheng Zhao ◽  
Qin Gao ◽  
Liu Pei ◽  
Chunhua Wang ◽  
Liang Jin ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Sensitivity And Specificity ◽  
Early Stage ◽  
New Technology ◽  
Laboratory Diagnosis ◽  
Treatment Monitoring ◽  
Current Status ◽  
Future Prospects ◽  
Death Rates ◽  
New Biomarkers

Hepatocellular carcinoma (HCC) has one of the highest death rates of any cancer in the world, and its incidence is increasing worldwide. Early-stage diagnosis of HCC is thus crucial for medical treatment. Detection of tumor biomarkers is one of the main methods for the early diagnosis of HCC. At present, α-fetoprotein (AFP) is the most practical serum biomarker for HCC diagnosis. However, the diagnostic accuracy of HCC with serum AFP exhibits both sensitivity and specificity far below satisfaction, especially with small sizes of HCC. As a result, the discovery of new biomarkers and/or their combination to enhance both the sensitivity and specificity for laboratory diagnosis of HCC is a crucial goal. With the development of new technology and advances in research, a number of new and specific biomarkers of HCC have been discovered. These biomarkers and their applications for the diagnosis, treatment monitoring and prognosis prediction of HCC, are reviewed in this article.

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