Nasopharyngeal carcinoma: staging work-up and surveillance

2014 ◽  
pp. 111-120
Author(s):  
Azita S Khorsandi ◽  
Kenneth Hu
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Work Up

Staging of untreated nasopharyngeal carcinoma with PET/CT: comparison with conventional imaging work-up

2008 ◽  
Vol 36 (1) ◽  
pp. 12-22 ◽  
Author(s):  
Shu-Hang Ng ◽  
Sheng-Chieh Chan ◽  
Tzu-Chen Yen ◽  
Joseph Tung-Chieh Chang ◽  
Chun-Ta Liao ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Conventional Imaging ◽  
Pet Ct ◽  
Work Up

Chemotherapy of metastatic and/or recurrent undifferentiated nasopharyngeal carcinoma with cisplatin, bleomycin, and fluorouracil.

1991 ◽  
Vol 9 (9) ◽  
pp. 1675-1681 ◽  
Author(s):  
H Boussen ◽  
E Cvitkovic ◽  
J L Wendling ◽  
N Azli ◽  
M Bachouchi ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Performance Status ◽  
World Health ◽  
North African ◽  
Global Rate ◽  
Pretreated Group ◽  
Health Organization ◽  
Intensive Work ◽  
Work Up ◽  
Undifferentiated Nasopharyngeal Carcinoma

Undifferentiated nasopharyngeal carcinoma (UCNT) is known to be radiosensitive and chemosensitive, but the latter has never been studied prospectively with phase II methodology. After an intensive work-up, 49 patients with recurrent (REC) and/or metastatic (MTS) UCNT were treated with three monthly cycles of cisplatin (CDDP) 100 mg/m2 day 1; bleomycin 15 mg intravenously (IV) day 1, and 16 mg/m2/d continuous infusion (CI) days 1 to 5; and fluorouracil (5FU) 650 mg/m2/d CI days 1 to 5 (PBF). Of the 49 patients, 33 were North African. The sex ratio was three males:one female, and the median World Health Organization (WHO) performance status was 1.6. In the 48 patients assessable for response, we observed nine (19%) complete responses (CRs) and 29 (60%) partial responses (PRs) (60%), for a 79% overall response rate (95% confidence interval, 68% to 90%) in the assessable group and a 78% global rate. There were eight CRs (24%) observed in the group without previous chemotherapy (33 patients) compared with one CR in the chemotherapy pretreated group (16 patients). Four patients are still alive without evidence of disease after 52+, 54+, 58+, and 58+ months, respectively. All of them had less than three bone MTS sites, and received radiation therapy in these sites. The results confirm the chemosensitivity of UCNT, and the observation of unmaintained long-term responders makes curability a possible consideration.

scholarly journals Staging of untreated nasopharyngeal carcinoma with PET/CT: comparison with conventional imaging work-up

2009 ◽  
Vol 36 (3) ◽  
pp. 538-538 ◽  
Author(s):  
Shu-Hang Ng ◽  
Sheng-Chieh Chan ◽  
Tzu-Chen Yen ◽  
Joseph Tung-Chieh Chang ◽  
Chun-Ta Liao ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Conventional Imaging ◽  
Pet Ct ◽  
Work Up

scholarly journals 18F-FDG PET Can Replace Conventional Work-up in Primary M Staging of Nonkeratinizing Nasopharyngeal Carcinoma

2007 ◽  
Vol 48 (10) ◽  
pp. 1614-1619 ◽  
Author(s):  
F.-Y. Liu ◽  
C.-Y. Lin ◽  
J. T. Chang ◽  
S.-H. Ng ◽  
S.-C. Chin ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Fdg Pet ◽  
18F Fdg ◽  
Work Up

An Established Epithelial Cell Line (NPC/HK1) from a Nasopharyngeal Carcinoma - II. A Sem Study

1982 ◽  
Vol 40 ◽  
pp. 224-225
Author(s):  
Li C.L. ◽  
Chew E.C. ◽  
Huang D.P. ◽  
Ho H.C. ◽  
Mak L.S. ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Epithelial Cell ◽  
Surface Morphology ◽  
Cell Line ◽  
Epithelial Cell Line ◽  
Present Communication ◽  
Cells In Culture ◽  
Sem Study ◽  
Well Differentiated

An epithelial cell line, NPC/HK1, has recently been successfully established from a nasopharyngeal carcinoma of the moderately to well differentiated squamous type. The present communication reports on the surface morphology of the NPC/HK1 cells in culture.

Studies of Epstein-Barr Virus Antigens Using Immunoperoxidase and Immunofluorescence Techniques

1975 ◽  
Vol 33 ◽  
pp. 342-343
Author(s):  
R. Stephens ◽  
K. Traul ◽  
D. Woolf ◽  
P. Gaudreau
Keyword(s):  
Electron Microscopy ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
If Technique ◽  
Infected Cells ◽  
Virus Antigens ◽  
Epstein Barr ◽  
Virus Capsid Antigen ◽  
Antigen Reactivity

A number of antigens have been found associated with persistent EBV infections of lymphoblastoid cells. Identification and localization of these antigens were principally by immunofluorescence (IF) techniques using sera from patients with nasopharyngeal carcinoma (NPC), Burkitt lymphoma (BL), and infectious mononucleosis (IM). Our study was mainly with three of the EBV related antigens, a) virus capsid antigen (VCA), b) membrane antigen (MA), and c) early antigens (EA) using immunoperoxidase (IP) techniques with electron microscopy (EM) to elucidate the sites of reactivity with EBV and EBV infected cells.Prior to labeling with horseradish peroxidase (HRP), sera from NPC, IM, and BL cases were characterized for various reactivities by the indirect IF technique. Modifications of the direct IP procedure described by Shabo and the indirect IP procedure of Leduc were made to enhance penetration of the cells and preservation of antigen reactivity.

Thorough Work-Up Crucial in Sarcoidosis Cases

2012 ◽  
Vol 43 (6) ◽  
pp. 26
Author(s):  
DOUG BRUNK
Keyword(s):  
Work Up

Neuropsychiatric Work-Up Same for SLE Patient

2011 ◽  
Vol 44 (1) ◽  
pp. 30
Author(s):  
DIANA MAHONEY
Keyword(s):  
Work Up

Bedeutung der allergologischen Abklärung bei Asthma und COPD

2014 ◽  
Vol 71 (5) ◽  
pp. 267-274
Author(s):  
Judith A. Schneider Spence ◽  
Andreas J. Bircher ◽  
Kathrin Scherer Hofmeier
Keyword(s):  
Respiratory Disease ◽  
Asthma Bronchiale ◽  
Aspirin Exacerbated Respiratory Disease ◽  
Work Up

Während eine allergologische Abklärung im Work-Up eines Asthma bronchiale inbegriffen sein sollte, wird die chronisch obstruktive Pneumopathie nicht spontan mit einer atopischen Diathese in Zusammenhang gebracht. Anamnese, Klinik, das Vorhandensein weiterer atopischer Krankheiten sowie Prickteste und die serologische Messung von spezifischen IgE-Antikörpern geben Hinweise auf eine allergische Genese einer akuten oder chronischen Lungenkrankheit. Der Stickoxidwert in der Ausatemluft (FeNO-Messung) kann durch die Infiltration von Eosinophilen in die Bronchialwand beim allergischen Phänotyp des Asthma bronchiale erhöht sein (TH2-gewichteter Phänotyp). Eine Abhängigkeit der Beschwerden vom Arbeitsplatz muss evaluiert werden. Neben dem allergischen Typ des Asthma bronchiale soll auch an eine Aspirin-exacerbated-respiratory disease (AERD) gedacht werden. Aufgrund der überlappenden pathophysiologischen Grundlagen und der Symptomatik zwischen Asthma bronchiale und der chronisch obstruktiven Pneumopathie ist die Zuweisung zum Allergologen allenfalls auch bei einem COPD-Patienten indiziert.

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