Poly(ADP-ribose) polymerase inhibitors and epithelial ovarian cancer

2012 ◽  
pp. 156-170
Author(s):  
Thomas P McNally ◽  
Gillianne GY Lai ◽  
Richard T Penson
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Polymerase Inhibitors

scholarly journals Poly (ADP-ribose) polymerase inhibitors in the management of ovarian cancer

2018 ◽  
Vol 14 ◽  
pp. 174550571775069 ◽  
Author(s):  
Maurie Markman
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Drug Administration ◽  
Clinical Data ◽  
Food And Drug Administration ◽  
Gynecologic Oncology ◽  
Brca Gene ◽  
Polymerase Inhibitors ◽  
The Us ◽  
Relevant Role

There is considerable interest and enthusiasm within the clinical gynecologic oncology community regarding the potential for poly (ADP-ribose) polymerase inhibitors to play a critically relevant role in the management of epithelial ovarian cancer and particularly (although not exclusively) in the setting of known mutations in the BRCA gene. This review will briefly highlight the biological rational for the use of poly (ADP-ribose) polymerase inhibitors in this malignancy, followed by summary of currently available clinical data supporting the delivery of agents approved by the US Food and Drug Administration for non-investigative use.

Impact of extended cycles of chemotherapy on survival outcome in recurrent epithelial ovarian cancer

2020 ◽  
Vol 159 ◽  
pp. 346-347
Author(s):  
W.Y. Hwang ◽  
S.I. Kim ◽  
M. Lee ◽  
K. Kim ◽  
J.H. No ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Survival Outcome

Die personalisierte Therapie beim Ovarialkarzinom

2018 ◽  
Vol 39 (03) ◽  
pp. 180-186
Author(s):  
Ann-K. Langner ◽  
Nina Pauly ◽  
Beyhan Ataseven ◽  
Andreas du Bois
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Personalisierte Medizin ◽  
Personalisierte Therapie

Die Behandlung des epithelialen Ovarial-, Tuben- und Peritonealkarzinoms (epithelial ovarian cancer; EOC) fußt auf 3 Säulen, die in unterschiedlichem Maße individualisierte bzw. personalisierte Medizin inkludieren:

BCL6 function and platin resistance in epithelial ovarian cancer

2018 ◽  
Author(s):  
M Eberhardt ◽  
N Häfner ◽  
D Kritsch ◽  
M Rengsberger ◽  
M Dürst ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer
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