Is stem cell research the future for Type 1 diabetes?

2015 ◽  
Vol 5 (6) ◽  
pp. 411-413
Author(s):  
Robert R Henry
2016 ◽  
Vol 101 (5) ◽  
pp. 2141-2148 ◽  
Author(s):  
Olga Graciela Cantú-Rodríguez ◽  
Fernando Lavalle-González ◽  
Miguel Ángel Herrera-Rojas ◽  
José Carlos Jaime-Pérez ◽  
José Ángel Hawing-Zárate ◽  
...  

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1589
Author(s):  
Ryota Inoue ◽  
Kuniyuki Nishiyama ◽  
Jinghe Li ◽  
Daisuke Miyashita ◽  
Masato Ono ◽  
...  

Stem cell therapy using islet-like insulin-producing cells derived from human pluripotent stem cells has the potential to allow patients with type 1 diabetes to withdraw from insulin therapy. However, several issues exist regarding the use of stem cell therapy to treat type 1 diabetes. In this review, we will focus on the following topics: (1) autoimmune responses during the autologous transplantation of stem cell-derived islet cells, (2) a comparison of stem cell therapy with insulin injection therapy, (3) the impact of the islet microenvironment on stem cell-derived islet cells, and (4) the cost-effectiveness of stem cell-derived islet cell transplantation. Based on these various viewpoints, we will discuss what is required to perform stem cell therapy for patients with type 1 diabetes.


2009 ◽  
Vol 35 (2) ◽  
pp. 85-93 ◽  
Author(s):  
L. Vija ◽  
D. Farge ◽  
J.-F. Gautier ◽  
P. Vexiau ◽  
C. Dumitrache ◽  
...  

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