Mathematical models of lipoprotein metabolism and kinetics: current status and future perspective

2013 ◽  
Vol 8 (5) ◽  
pp. 595-604 ◽  
Author(s):  
James Lu ◽  
Norman A Mazer ◽  
Katrin Hübner
Keyword(s):  
Mathematical Models ◽  
Lipoprotein Metabolism ◽  
Current Status ◽  
Future Perspective

Current Status and Future Perspective for Research on Medicinal Plants with Anticancerous Activity and Minimum Cytotoxic Value

2019 ◽  
Vol 20 (12) ◽  
pp. 1227-1243
Author(s):  
Hina Qamar ◽  
Sumbul Rehman ◽  
D.K. Chauhan
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Anticancer Agents ◽  
Drug Targets ◽  
Psidium Guajava ◽  
Current Status ◽  
Future Perspective ◽  
Wide Range

Cancer is the second leading cause of morbidity and mortality worldwide. Although chemotherapy and radiotherapy enhance the survival rate of cancerous patients but they have several acute toxic effects. Therefore, there is a need to search for new anticancer agents having better efficacy and lesser side effects. In this regard, herbal treatment is found to be a safe method for treating and preventing cancer. Here, an attempt has been made to screen some less explored medicinal plants like Ammania baccifera, Asclepias curassavica, Azadarichta indica, Butea monosperma, Croton tiglium, Hedera nepalensis, Jatropha curcas, Momordica charantia, Moringa oleifera, Psidium guajava, etc. having potent anticancer activity with minimum cytotoxic value (IC50 >3μM) and lesser or negligible toxicity. They are rich in active phytochemicals with a wide range of drug targets. In this study, these medicinal plants were evaluated for dose-dependent cytotoxicological studies via in vitro MTT assay and in vivo tumor models along with some more plants which are reported to have IC50 value in the range of 0.019-0.528 mg/ml. The findings indicate that these plants inhibit tumor growth by their antiproliferative, pro-apoptotic, anti-metastatic and anti-angiogenic molecular targets. They are widely used because of their easy availability, affordable price and having no or sometimes minimal side effects. This review provides a baseline for the discovery of anticancer drugs from medicinal plants having minimum cytotoxic value with minimal side effects and establishment of their analogues for the welfare of mankind.

Emerging 3D printing technologies for drug delivery devices: Current status and future perspective

2021 ◽  
Author(s):  
Jiawei Wang ◽  
Yu Zhang ◽  
Niloofar Heshmati Aghda ◽  
Amit Raviraj Pillai ◽  
Rishi Thakkar ◽  
...  
Keyword(s):  
Drug Delivery ◽  
3D Printing ◽  
Current Status ◽  
Future Perspective ◽  
Drug Delivery Devices

scholarly journals Endoscopic screening for gastric cancer in Japan: Current status and future perspective

2021 ◽  
Author(s):  
Katsuhiro Mabe ◽  
Kazuhiko Inoue ◽  
Tomoari Kamada ◽  
Katsuaki Kato ◽  
Mototsugu Kato ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Current Status ◽  
Future Perspective ◽  
Endoscopic Screening

scholarly journals Status and Perspectives of Commercial Aircraft Morphing

Biomimetics ◽  
2022 ◽  
Vol 7 (1) ◽  
pp. 11
Author(s):  
Michelangelo Giuliani ◽  
Ignazio Dimino ◽  
Salvatore Ameduri ◽  
Rosario Pecora ◽  
Antonio Concilio
Keyword(s):  
General Aviation ◽  
Current Status ◽  
Future Perspective ◽  
Commercial Aircraft

In a previous paper, the authors dealt with the current showstoppers that inhibit commercial applicability of morphing systems. In this work, the authors express a critical vision of the current status of the proposed architectures and the needs that should be accomplished to make them viable for installation onboard of commercial aircraft. The distinction is essential because military and civil issues and necessities are very different, and both the solutions and difficulties to be overcome are widely diverse. Yet, still remaining in the civil segment, there can be other differences, depending on the size of the aircraft, from large jets to commuters or general aviation, which are classifiable in tourism, acrobatic, ultralight, and so on, each with their own peculiarities. Therefore, the paper aims to trace a common technology denominator, if possible, and envisage a future perspective of actual applications.

scholarly journals Aspetos da gramaticalização de 'ir' como verbo auxiliar temporal

2020 ◽  
pp. 213-239
Author(s):  
Telmo Móia
Keyword(s):  
Current Status ◽  
Future Perspective ◽  
Ongoing Process ◽  
Center Stage ◽  
Auxiliary Verb

In this paper, various aspects concerning the grammaticalization of ir (‘go’) into a temporal auxiliary verb are considered, focusing on its current status as a posteriority operator in competition with various temporal suffixes of the tense system. Four issues will hold center stage: its coexistence with explicit posteriority tense suffixes, without a sense of redundancy emerging; its use in non-past and past scenarios in competition with the synthetic future and with the synthetic conditional, or imperfective past, respectively; its possible use in structures expressing an anteriority location relation (in association with future perspective points); its inflection in subjunctive, gerundive and infinitival forms, a rather poorly studied possibility. The overall conclusion will be that the grammaticalization process affecting ir is still an ongoing process, which can be seen not only in the aspects studied apropos the abovementioned four issues, but also in a few other aspects – namely regarding the scarcity of its combination with some classes of predicates – that will be left for further research.

Sign in / Sign up

Export Citation Format

Share Document