scholarly journals Chemical Characterisation of Medicinally Important Solanaceous plant Solanum xanthocarpum Schrad & Wendl

2018 ◽  
Vol 14 (01) ◽  
pp. 22-25
Author(s):  
KUMUD MODI ◽  
◽  
NEHA JATAV ◽  
Keyword(s):  
Solanaceous Plant ◽  
Solanum Xanthocarpum

Liquorice exaggerates protective action of Solanum xanthocarpum against cigarette smoke induced pulmonary inflammation

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
RA Manek ◽  
NR Sheth ◽  
JR Chavda ◽  
JD Vaghasiya ◽  
KP Modi ◽  
...  
Keyword(s):  
Cigarette Smoke ◽  
Protective Action ◽  
Pulmonary Inflammation ◽  
Solanum Xanthocarpum

OPTIMIZATION OF DRYING AND STORAGE PARAMETERS OF SOLANUM XANTHOCARPUM USING MOISTURE ISOTHERMS

2014 ◽  
pp. 229-236
Author(s):  
D.A.N. Dharmasena ◽  
H.M.W.P. Herath ◽  
T. Sivananthawerl ◽  
K.B. Palipane
Keyword(s):  
And Storage ◽  
Solanum Xanthocarpum

scholarly journals Potential Hepatoprotective Effect of Solanum xanthocarpum Against CCl4 Induced Hepatotoxicity in Albino Rats

2014 ◽  
Vol 26 (1) ◽  
pp. 230-232
Author(s):  
B. Dheeba ◽  
P. Sampathkumar ◽  
S. Vijay ◽  
K. Kannan ◽  
M. Kannan
Keyword(s):  
Hepatoprotective Effect ◽  
Albino Rats ◽  
Solanum Xanthocarpum

Study on Herb-herb Interaction Potential of Glycyrrhiza glabra with Solanum xanthocarpum and Adhatoda vasica on Mast Cell Stabilizing Activity

2011 ◽  
Vol 7 (5) ◽  
pp. 589-598 ◽  
Author(s):  
Ravi A. Manek ◽  
Navin R. Sheth ◽  
Jitendra D. Vaghasiya ◽  
Shailesh V. Malaviya ◽  
Nurudin P. Jivani ◽  
...  
Keyword(s):  
Mast Cell ◽  
Interaction Potential ◽  
Glycyrrhiza Glabra ◽  
Adhatoda Vasica ◽  
Solanum Xanthocarpum

Structure-Based Docking Studies of GLUT4 Towards Exploring Selected Phytochemicals from Solanum xanthocarpum as a Therapeutic Target for the Treatment of Cancer

2019 ◽  
Vol 16 (4) ◽  
pp. 406-416 ◽  
Author(s):  
Babatunji Emmanuel Oyinloye ◽  
Tayo Alex Adekiya ◽  
Raphael Taiwo Aruleba ◽  
Oluwafemi Adeleke Ojo ◽  
Basiru Olaitan Ajiboye
Keyword(s):  
Glucose Transporter ◽  
Environmental Influence ◽  
Glucose Consumption ◽  
Docking Studies ◽  
The Body ◽  
Lipinski’S Rule ◽  
Pubchem Database ◽  
Potential Inhibitors ◽  
Cancerous Cells ◽  
Solanum Xanthocarpum

Background: In recent years, there has been an exponential increase in the global burden of cancer which has been associated with several factors including environmental influence, aging, diet, infectious agents, hormonal imbalance and chronic inflammation, among others. Cancerous cells utilize more glucose for its proliferation and survival than normal cells. Thus, the regulation of glucose consumption of cancerous cells through the inhibition of glucose transporter-4-protein (GLUT4) encoded by solute carrier family-2-member-4-gene (Slc2a4) by selected phytochemicals from Solanum xanthocarpum may serve as a new therapeutic candidate for the treatment of cancer. Methods: The seven identified potential inhibitors of GLUT4 from Solanum xanthocarpum were retrieved from PubChem database. Examination of their drug-likeness, toxicity prediction and molecular docking studies of these compounds with GLUT4 were carried out using online tools such as Molinspiration, PreADMET V.2.0 and Patchdock server. Results: The findings revealed that, five out of the seven compounds fulfil oral drugability of Lipinski’s rule of five (RO5) while two slightly meet the criteria of RO5. Conversely, five of the compounds are predicted to be mutagen while the remaining two are predicted to be safe for the body. Additionally, stigmasterol glucoside has higher binding-affinity (7590) with GLUT4 when compared to doxorubicin (6600) the control. Conclusion: These findings suggest that stigmasterol glucoside from Solanum xanthocarpum could be a promising therapeutic agent with better therapeutic efficacy than doxorubicin in the treatment of cancer via the inhibition of GLUT4.

Solanum xanthocarpum (Yellow-berried nightshade)

2019 ◽  
pp. 2455-2455
Author(s):  
K. Subramanya Sastry ◽  
Bikash Mandal ◽  
John Hammond ◽  
S. W. Scott ◽  
R. W. Briddon
Keyword(s):  
Solanum Xanthocarpum

Antinociceptive activity of the aerial parts of Solanum xanthocarpum

Fitoterapia ◽  
2003 ◽  
Vol 74 (1-2) ◽  
pp. 119-121 ◽  
Author(s):  
M.T Rahman ◽  
M Ahmed ◽  
M Alimuzzaman ◽  
J.A Shilpi
Keyword(s):  
Antinociceptive Activity ◽  
Aerial Parts ◽  
Solanum Xanthocarpum

scholarly journals Evaluation of antihepatotoxic potential of Solanum xanthocarpum fruit extract against antitubercular drugs induced hepatopathy in experimental rodents

2012 ◽  
Vol 2 (6) ◽  
pp. 454-460 ◽  
Author(s):  
Talib Hussain ◽  
Ramesh K Gupta ◽  
K Sweety ◽  
Mohd Sajid Khan ◽  
Md Sarfaraj Hussain ◽  
...  
Keyword(s):  
Fruit Extract ◽  
Antitubercular Drugs ◽  
Solanum Xanthocarpum

Induced morphogenesis in tissue cultures of Solanum xanthocarpum

Planta ◽  
1968 ◽  
Vol 81 (4) ◽  
pp. 372-375 ◽  
Author(s):  
P. S. Rao ◽  
S. Narayanaswami
Keyword(s):  
Tissue Cultures ◽  
Solanum Xanthocarpum
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