scholarly journals Faktor risiko dan asupan isoflavon pada pasien kanker payudara

2014 ◽  
Vol 10 (4) ◽  
pp. 218
Author(s):  
I Wayan Dwija Karyasa ◽  
Johan Kurnianda ◽  
Herni Astuti
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Cancer Patients ◽  
Hormone Replacement ◽  
Healthy People ◽  
Health Examination ◽  
Breast Cancer Patients ◽  
Oncologic Surgery ◽  
The Status ◽  
The Difference

Background: Breast cancer is noncommunicable chronic disease the prevalence of which is increasing all over the world, including in Indonesia and particularly East Java. Causes of breast cancer are unknown. Some studies show risk factors for breast cancer are hormonal, genetic, reproductive and endocrinologic factors. There is the isoflavon compound in soybeans that is known as anti-cancer with anti-estrogen activities.Objective: The study was aimed at identifying risk factor and the difference of isoflavone intake between breast cancer patients and healthy people in hospitals.Method: The study was analytic observational using matched case-control study design at comparison 1:2 with matching on a status of menopause. Cases were positive receptor estrogen breast cancer patients newly diagnosed during the first visit at hospital outpatient Oncologic Surgery Polyclinic. Controls were staff considered healthy based on the result of health examination at Dr. Ramelan Naval Hospital of Surabaya. Cases comprised 49 people and control 98 people taken through consecutive method. Data consisted of an identity of samples, weight, height, isoflavone intake, family history, use of hormone replacement therapy and parity. Intake of isoflavones was obtained from semiquantitative food frequency questionnaire (SQ-FFQ) and statistical test used Chi-Square and Odd Ratio (OR).Results: There was the difference in isoflavone intake and family history between cases and controls (p<0.05) and there was an association between isoflavone intake (OR=2.58; p=0.007) and family history (OR=18; p=0.002) and the incidence of breast cancer. There was no association between the status of obesity, parity, and use of hormone replacement therapy.Conclusion: There are differences in isoflavone intake of breast cancer patients compared with healthy people and there was no difference in the status of obese breast cancer patients compared to healthy individuals and isoflavone intake less 2.85 times the risk of breast cancer compared with adequate intake of isoflavones.

scholarly journals Evaluating the Effect of Health Education Intervention on the Health Beliefs and Behaviors of First-Degree Female Relatives of Breast Cancer Patients

2021 ◽  
Author(s):  
Sule Olgun ◽  
Berna Dizer
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Health Education ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cancer Patients ◽  
Health Beliefs ◽  
Breast Cancer Patients ◽  
History Of ◽  
And Behaviors

Abstract Background Breast cancer risk increases by 80% in the presence of BRCA1 and BRCA2 gene mutations in the same family. In particular, a woman whose sister or mother has breast cancer has a 2- to 5-fold higher risk of developing breast cancer compared with other women. For this reason, recommendations should have been made regarding breast cancer prevention and/or early detection for women with first-degree family history of breast cancer. Aim The aim of this study was to evaluate the effect of health education, which was provided to first-degree female relatives of breast cancer patients, on their health beliefs and behaviors. Study Design and Methods The study sample included 50 women with a first-degree relative being treated for breast cancer in the chemotherapy and radiotherapy unit of a university hospital. A one-group pretest-posttest design was used. The pretest consisted of the health belief model scale and a questionnaire regarding the women’s sociodemographic information and breast cancer screening behaviors. After the pretest, the patients received health education regarding breast cancer risk factors and screening methods. The posttest was conducted 3 weeks after the education using the same assessment tools. Results After education, there were statistically significant increases in rates of practicing breast self-examination, having clinical breast examinations, and undergoing breast ultrasound/mammography compared with pretest results. Conclusions Health workers should possess knowledge and experience about breast cancer which will enable them to effectively undertake an educational role, especially for high-risk groups such as women with first-degree family history of breast cancer.

Breast-conservation therapy in early-stage breast cancer patients with a positive family history

2002 ◽  
Vol 9 (9) ◽  
pp. 912-919 ◽  
Author(s):  
Georges Vlastos ◽  
Nadeem Q. Mirza ◽  
Funda Meric ◽  
Kelly K. Hunt ◽  
Attiqa N. Mirza ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Cancer Patients ◽  
Early Stage ◽  
Positive Family History ◽  
Breast Conservation ◽  
Breast Conservation Therapy ◽  
Early Stage Breast Cancer ◽  
Breast Cancer Patients

Effect of Nursing Measures Based on Self-Efficacy Theory on State Self-Esteem of Breast Cancer Patients

2021 ◽  
Vol 7 (6) ◽  
pp. 6469-6476
Author(s):  
Li Qiu ◽  
Hongli Wang ◽  
Yuan Yuan ◽  
Ying Wang ◽  
Ping Yu
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Self Efficacy ◽  
Self Esteem ◽  
The Self ◽  
Control Group ◽  
Observation Group ◽  
Breast Cancer Patients ◽  
Functional Exercise ◽  
The Difference

To analyze the effect of nursing measures based on self-efficacy theory on the state self-esteem of breast cancer patients. 110 breast cancer patients who were treated in our hospital from October 2018 to October 2019 were randomly divided into control group and observation group. The control group was given routine nursing measures, and the observation group was given nursing measures under the guidance of self-efficacy theory. Before operation, 1 week after operation and 3 months after operation, the general data of the two groups before and after treatment were recorded. The self-efficacy level and self-esteem level of the patients before and after treatment were assessed by the self-efficacy scale (GSEs) and state self-esteem scale (SSEs). The compliance of functional exercise and shoulder joint activity (ROM) of the two groups were compared, and the physical status of the two groups were analyzed. To analyze the effect of nursing measures based on self-efficacy theory on the state self-esteem of breast cancer patients. The GSEs score of the two groups increased with the time, and there was no significant difference between the two groups before operation (P > 0.05). After 1 week and 3 months, the GSEs score of the observation group was significantly higher than that of the control group (P < 0.05). The compliance evaluation table of functional exercise in the two groups increased with the time, and the compliance evaluation table of functional exercise in the observation group was significantly higher than that in the control group, the difference was statistically significant (P < 0.05). ROM of the two groups increased with time, and ROM of the observation group was significantly better than that of the control group, the difference was statistically significant (P < 0.05). The self-esteem level of the two groups increased with time, and the self-esteem level of the observation group was significantly higherthan that of the control group, the difference was statistically significant (P <0.05). The nursing measures under tne guidance of self-efficacy theory can help patients to complete functionalexercise, improve theirquality of life, improve their self-esteem level, a nd can be widely used in clinical practice.

scholarly journals ALDH1 Expression and Vasculogenic Mimicry Are Positively Associated with Poor Prognosis in Patients with Breast Cancer

2018 ◽  
Vol 49 (3) ◽  
pp. 961-970 ◽  
Author(s):  
Peng Xing ◽  
Huiting Dong ◽  
Qun Liu ◽  
Tingting Zhao ◽  
Fan Yao ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Cox Regression ◽  
Histological Grade ◽  
Vasculogenic Mimicry ◽  
Disease Free Survival ◽  
Breast Cancer Patients ◽  
Double Positive ◽  
The Status ◽  
Aldh1 Expression

Background/Aims: This study aimed to explore the prognostic value of aldehyde dehydrogenase 1 (ALDH1) expression and vasculogenic mimicry (VM) in patients with breast cancer. Methods: ALDH1 expression and the presence of VM were examined by immunohistochemistry and CD31/PAS double staining, respectively, using formalin-fixed paraffin-embedded tissues from 202 breast cancer patients. The mean follow-up period ranged from 15 to 115 months. The Kaplan-Meier method was used to plot survival curves. Prognostic values were assessed by multivariate analysis using the Cox regression model. Results: ALDH1 expression was strongly associated with VM (P = 0.005). ALDH1 expression was positively correlated with histological grade (P = 0.011). Both ALDH1 expression and VM were negatively related to the status of the estrogen receptor and progesterone receptor and were statistically increased in triple-negative breast cancer. Patients with ALDH1 expression or VM displayed poorer disease-free survival (DFS) and overall survival (OS) than ALDH1-negative or VM-negative patients, with the worst OS and DFS observed in ALDH1/VM-double-positive patients. ALDH1-positive and VM-positive were independent survival risk factors for DFS and OS. Conclusion: ALDH1 expression and VM are correlated with the survival rate of patients with breast cancer. ALDH1 and VM, either alone or together, are prognostic factors in patients with breast cancer.

Is family history related to preventive health behaviors and medical management in breast cancer patients?

2005 ◽  
Vol 90 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Lisa Madlensky ◽  
Shirley W. Flatt ◽  
Wayne A. Bardwell ◽  
Cheryl L. Rock ◽  
John P. Pierce ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Health Behaviors ◽  
Cancer Patients ◽  
Medical Management ◽  
Preventive Health ◽  
Breast Cancer Patients ◽  
Preventive Health Behaviors

Physician age and surveillance intensity following curative-intent treatment for breast cancer patients.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 6081-6081
Author(s):  
Steven F. Abboud ◽  
Emad S. Allam ◽  
Julie A. Margenthaler ◽  
Ling Chen ◽  
Katherine S. Virgo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Liver Function Tests ◽  
Post Treatment ◽  
Breast Cancer Patients ◽  
Curative Intent ◽  
Clinical Vignettes ◽  
Serum Cea ◽  
The Difference ◽  
Surveillance Practice

6081 Background: Breast carcinoma is a large health care concern for patients, physicians, and society. 2.5 million women have been treated for breast cancer and are candidates for surveillance in the US. We have documented dramatic variation in post-treatment surveillance strategies utilized by ASCO experts caring for such patients. Since it is often asserted that younger physicians order more tests than older physicians, we sought to measure the effect of clinician age on post-treatment surveillance intensity for breast cancer patients by analyzing a recent survey of ASCO members. Methods: We surveyed the 3245 ASCO members who indicated that breast cancer treatment was a major focus of their practice. 4 succinct clinical vignettes describing generally healthy women with breast cancer of varying prognoses and a menu of 12 surveillance modalities were offered. The menu was chosen after a literature search indicated that no other surveillance tests were commonly used. We analyzed data from one of the 4 idealized vignettes only (the patient with TNM IIA carcinoma) and stratified responses by clinician age. Practice patterns were compared by years after completion of training (0-10, 11-20, 21-30, 30-40, >40 years), a surrogate measure of physician age. Statistical analysis employed ANOVA. Results: There were 1012 responses; 915 were evaluable. Statistically significant differences were observed across age strata for CBC, liver function tests (LFTs), and serum CEA level only. For example, ASCO clinicians in practice for 0-10 years after completion of training recommended CBCs 1.3 + 1.4 (mean + SD) times in year 1. Those > 40 years after completion of training recommended CBCs 2.4 + 1.3 times in year 1 (p<0.001). Conclusions: Younger physicians recommend statistically significantly fewer CBCs, LFTs, and serum CEA levels during post-treatment surveillance than older physicians. However, the magnitude of the difference is clinically small for all 3 modalities and does not explain the known overall variation in surveillance practice among clinically active experts.

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