scholarly journals Perubahan kadar hemoglobin akibat terapi kurkuminoid ekstrak rimpang kunyit dibandingkan natrium diklofenak pada penderita osteoartritis

2011 ◽  
Vol 7 (3) ◽  
pp. 146
Author(s):  
Nyoman Kertia ◽  
Ahmad Husain Asdie ◽  
Wasilah Rochmah ◽  
Marsetyawan Marsetyawan
Keyword(s):  
Treatment Group ◽  
Side Effects ◽  
Group Treatment ◽  
Educational Level ◽  
Diclofenac Sodium ◽  
Hemoglobin Level ◽  
Treatment Results ◽  
Treatment Groups ◽  
Natural Medicine ◽  
Before And After

Background: In general, patients with osteoarthritis require long live treatments, especially anti-infammatory drugs. Non steroidal anti infammatory drugs are mostly follow by some side effects such as dyspepsia and gastrointestinal bleeding. The use of natural medicine for rheumatic diseases have commonly been practiced worldwide.Objectives: To learn the changes of hemoglobin level due to treatment with curcuminoid from Curcuma domestica Val. rhizome extract compared to diclofenac sodium as anti-infammatory agent for the treatment of osteoarthritis.Methods: This research is a prospective randomized open end blinded evaluations (PROBE). Patients treated with 30 mg curcuminoid from Curcuma domestica Val. rhizome extract or 25 mg diclofenac sodium three times daily for 4 weeks respectively.The hemoglobin level was checked before and after treatment. Results: A total of 80 patients with knee osteoarthritis participated in this study. There was no signifcant difference in the frequency of sex, educational level, duration of suffering, percentage of co-morbidities in both groups. There was no signifcant different of hemoglobin level before treatment between both treatment group. The hemoglobin level was increase signifcantly in curcuminoid treatment groups while no signifcant change in diclofenac group. Treatment with curcuminoid increasing the hemoglobin level signifcantly compare to diclofenac sodium (p=0.03).Conclusion: Treatment with curcuminoid from Curcuma domestica Val. rhizome increasing the hemoglobin level signifcantly compare to diclofenac sodium treatment for osteoarthritis.

Perbandingan Efek Suplementasi Tablet Tambah Darah Dengan Dan Tanpa Vitamin C Terhadap Kadar Hemoglobin Pada Ibu Hamil Dengan Usiakehamilan 16-32 Minggu Di Desa Keniten Kecamatan Mojo Kabupaten Kediri

2017 ◽  
Vol 3 (1) ◽  
pp. 76
Author(s):  
Siti Asiyah ◽  
Dwi Estuning Rahayu ◽  
Wiranti Dwi Novita Isnaeni
Keyword(s):  
Treatment Group ◽  
Vitamin C ◽  
Gestational Age ◽  
Group Treatment ◽  
Sampling Technique ◽  
Hemoglobin Level ◽  
The Body ◽  
Control Group ◽  
Fetal Organ ◽  
And Control

The needed of Iron Tablet in pregnancy was increase than mother who not pregnant.  That  cause of  high metabolism at the pregnancy for formed of  fetal organ and energy. One of effort for prevent anemia in mother pregnant with giving the Iron tablet and vitamin c. The reason of  this research in 4 June – 11 July 2014 is for compare the effect of  iron tablet suplementation with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks In Desa Keniten Kecamatan Mojo Kabupaten Kediri. This research method using comparative analytical.  Research design type of Quasy Eksperiment that have treatment group and control group. Treatment group will giving by Iron tablet and 100 mg vitamin C, and control group just giving by iron tablet during 21 days. Population in this research are all of mother pregnant with Gestational Age Of 16-32 Weeks with Sampling technique is  cluster random sampling is 29 mother pregnant. Comparison analysis of  iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks, data analysis using Mann Whitney U-test and the calculated U value (44,5) less than U-table (51). So there was difference of iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks Therefore, the addition of vitamin C on iron intake is needed to increase the uptake of iron tablets. When the amount of iron uptake increases, the reserves of iron in the body will also increase, so as to prevent anemia in pregnant women; Keywords : Iron Tablet (Fe), Vitamin C, Hemoglobin level, Mother Pregnant

scholarly journals Efficacy of a New Non-drug Acne Therapy: Aloe Vera Gel Combined With Ultrasound and Soft Mask for the Treatment of Mild to Severe Facial Acne

2021 ◽  
Vol 8 ◽  
Author(s):  
Hongyu Zhong ◽  
Xiang Li ◽  
Wanqi Zhang ◽  
Xiaoxiao Shen ◽  
Yuangang Lu ◽  
...  
Keyword(s):  
Treatment Group ◽  
Side Effects ◽  
Combined Therapy ◽  
Aloe Vera ◽  
Physical Method ◽  
Control Group ◽  
Severe Acne ◽  
Aloe Vera Gel ◽  
Before And After ◽  
Acne Therapy

Background: Acne is a chronic disorder that affects almost 80% of adolescents and young adults, causing psychological and emotional distress. However, the current treatments for acne are either ineffective or have many side effects. This study was designed to confirm and objectively quantify the effect of a new non-drug combined therapy on acne.Methods: This study innovatively utilized ultrasound, which enhanced the absorption of aloe vera gel, and soft mask to make a purely physical method without any drugs. In both the treatment group and control group, the number of papules/pustules and the area of hyperpigmented lesions were counted, and a smart mirror intelligent face system was used before and after the combined therapy. Alterations in the skin functional index were recorded and analyzed statistically.Results: In the treatment group, the combined therapy significantly reduced the number of papules and the area of hyperpigmented lesions and improved skin roughness and local blood circulation. In the control group, there was no obvious improvement over 2 months.Conclusion: This study suggests that the new non-drug combined therapy significantly improved acne, which provided experimental evidence and treatment guidance for patients with mild to severe acne, especially patients with moderate acne. This new therapy may possibly be an appropriate method for patients who seek topical treatments with mild side effects and low antibiotic resistance rates.

scholarly journals Warm compresses to decrease dysmenorrhea among adolescents

2020 ◽  
Vol 3 (2) ◽  
pp. 110-114
Author(s):  
Dian Nurafifah ◽  
Ihda Mauliyah ◽  
Atiul Impartina
Keyword(s):  
Data Analysis ◽  
Treatment Group ◽  
Side Effects ◽  
Young Women ◽  
Control Group ◽  
Not Given ◽  
Menstrual Pain ◽  
Before And After ◽  
Experience Pain

Dysmenorrhea is one of discomfort experienced by adolescent during menstruation. A Survey of 10 young women at University of Muhammadiyah Lamongan found 90% had dysmenorrhea. To reduce pain, they take pain relievers. However, the use of drugs can cause side effects, especially if long-term use can lead to addiction or dependence. Research design using Quasy Eksperiment (pretest-posttest). The study was conducted on adolescents who are experiencing dysmenorrhea. They were divided into two groups namely control and treament groups. The study began by assessing pain levels in both groups. The treatment group was given warm compresses but the control group was not given any treatment, after that reassess the level of pain. The study analyzes changes in pain levels and compares pain change in the two groups. The results showed that in the control group most of the adolescents did not experience pain changes during dysmenorrhea (86.7%), whereas in the treatment group most of the adolescents experienced a decrease in pain (93.3%). Data analysis using the Mann Whitney test showed p=0.000 where p0.05 so it can be concluded that there are differences in dysmenorrhea before and after treatment between the warm compress group and the control group. The results of this study are expected to be used as consideration in developing plans to reduce discomfort in the form of menstrual pain in a non-pharmacological manner.

scholarly journals Perubahan Kualitas Sperma Mencit (Mus musculus) Yang Terpapar Asap Rokok Elektrik

2019 ◽  
Vol 3 (2) ◽  
pp. 122-128
Author(s):  
Andita Ayu Mandasari ◽  
Siti Nur Asiyah ◽  
Kurnia Lintang
Keyword(s):  
Treatment Group ◽  
Cigarette Smoke ◽  
Mus Musculus ◽  
Group Treatment ◽  
Time Lag ◽  
Cigarette Smoke Exposure ◽  
Control Group ◽  
Male Mice ◽  
Suction Device ◽  
Treatment Groups

Smoking is one of the habits that can affect human health. One type of cigarette that is currently the choice is electric cigarettes. The e-cigarette content includes nicotine, propylene glycol, flavorings and glycerin. The purpose of this study was to determine the effect of exposure to e-cigarette smoke on mice strain balb / c with the parameters of the number of spermatozoa. This study used 15 male mice which were 8-10 weeks old and weighed 25-30 grams of male mice which were divided into 3 treatment groups namely control group, treatment group one and treatment group two. In the control group no exposure to cigarette smoke was carried out while in the treatment group one was exposed to cigarette smoke in mice with a dose of 0 mg nicotine and the second treatment group was exposed to e-cigarette smoke at a dose of 18 mg nicotine. Electric cigarette smoke exposure is carried out for 30 days using a suction device from a syringe. The exposure of cigarette smoke is carried out every day with successive doses of 20 times as much as 3 times with a time lag of 10 minutes (5 minutes the chamber is closed and 5 minutes of the chamber is opened). The results showed that the average number of spermatozoa in the control group was 16.816 million / ml. The average number of spermatozoa in treatment one was 10.432 million / ml and the average number of spermatozoa in treatment two was 5.234 million / ml. This shows that exposure to cigarette smoke can reduce the number of spermatozoa from the control group to the first treatment by 42.56% and the second treatment shows a decrease from the first group by 34.65%.

scholarly journals Gene Expression of PSORI-CM01 and Yinxieling in the Treatment of Psoriasis Vulgaris

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Yue Lu ◽  
Yao Qi ◽  
Li Li ◽  
Yuhong Yan ◽  
Danni Yao ◽  
...  
Keyword(s):  
Gene Expression ◽  
Treatment Group ◽  
Differentially Expressed Genes ◽  
Psoriasis Vulgaris ◽  
Drug Action ◽  
Differentially Expressed ◽  
Signalling Pathways ◽  
Control Group ◽  
Treatment Groups ◽  
Before And After

Background. This study aimed to explore the mechanisms of action of the PSORI-CM01 and Yinxieling formulas in the treatment of patients with psoriasis vulgaris by analyzing gene expression in peripheral blood mononuclear cells (PBMCs). Methods. PBMC samples were collected from 21 patients before and after treatment. The study included nine patients in the PSORI-CM01 treatment group, 12 patients in the Yinxieling treatment group, and nine patients in the healthy control group. Gene expression levels in PBMCs were determined using the Affymetrix gene chip technology. Results. In the PSORI-CM01 group before and after treatment, a total of 668 differentially expressed genes were found, of which 445 were upregulated and 223 were downregulated. Before and after Yinxieling treatment, 657 differentially expressed genes were found, of which 168 were upregulated and 489 were downregulated. Venn analysis showed that 78 genes were not differentially expressed in the PSORI-CM01 group and 74 were not differentially expressed in the Yinxieling group compared with those in the controls. Among these genes, 72 genes were common to both groups, which were the genes on which the two drugs acted jointly. The results of KEGG analysis and Venn analysis on the signalling pathways of drug action in treatment groups showed that haemostasis and pathways involving Rho GTPases were common signalling pathways of drug action in the two groups. Conclusions. By a comparative analysis of the treatment groups, we found that both drugs have a positive effect on patients with psoriasis vulgaris, primarily by regulating the pathways related to platelet activation, aggregation, and blood coagulation. Trial registration: ChiCTR, ChiCTR-TRC-14005185, Registered 8 August 2014, http://www.chictr.org.cn/showproj.aspx?proj=4390

Clinical Observations on Postoperative Vomiting Treated by Auricular Acupuncture

2003 ◽  
Vol 31 (03) ◽  
pp. 475-480 ◽  
Author(s):  
Yongsuk Kim ◽  
Chang-Whan Kim ◽  
Keon-Sik Kim
Keyword(s):  
Treatment Group ◽  
Side Effects ◽  
Acupuncture Treatment ◽  
Postoperative Nausea And Vomiting ◽  
Auricular Acupuncture ◽  
Postoperative Vomiting ◽  
Treatment Groups ◽  
Female Patients ◽  
Clinical Observations ◽  
Significant Difference

We studied the effect of auricular acupuncture on postoperative nausea and vomiting (PONV). One hundred female patients undergoing transabdominal hysterectomy were entered into the study. The patients were divided into two groups (auricular acupuncture treatment group and non-treatment group) in order to test the effectiveness of auricular acupuncture. There was no significant difference in age, weight, height or duration of anesthesia among the two groups of patients. There was a significant difference between the control and auricular acupuncture treatment groups in the incidence of vomiting 12 hours after surgery (68% and 30%, respectively, p < 0.01). No noteworthy side effects from treatment were observed. Auricular acupuncture is effective in reducing vomiting following transabdominal hysterectomy in female patients.

Treatment of Acute Maxillary Sinusitis

1973 ◽  
Vol 82 (2) ◽  
pp. 186-191 ◽  
Author(s):  
Alf Axelsson ◽  
Nathan Chidekel ◽  
Cay Jensen ◽  
Nils Grebelius ◽  
Frans Singer
Keyword(s):  
Treatment Group ◽  
Side Effects ◽  
Statistical Difference ◽  
Maxillary Sinusitis ◽  
Optimal Treatment ◽  
Treatment Groups

This paper deals with the problem of finding the optimal treatment for acute maxillary sinusitis. Only sinuses with secretion were included. Comparison between the different modes of treatment was made by the aid of a radiological gradation of the sinus changes. Each treatment group consisted of 50 patients whose sinuses were radiologically investigated on day 1, 5, 10 and 15. Treatment was given for 10 days. Irrigation was performed every second day until the lavage content was clear. Side effects were investigated. All groups were statistically similar initially. There was no statistical difference between the four treatment groups with regard to healing after 5, 10 and 15 days of treatment. Few side effects were noted on doxycycline but some on spiramycin. Both antibiotics thus afford the advantage of omitting irrigation from the treatment.

scholarly journals COMPARATIVE STUDY ON THE EFFICACY OF MAITLAND TECHNIQUE (GRADE IV) AND MULLIGAN TECHNIQUE, IN THE TREATMENT OF FROZEN SHOULDER

2013 ◽  
Vol 2 (1) ◽  
pp. 10-14
Author(s):  
Syed Abid Mehdi Kazmi ◽  
Jharna Devi ◽  
Faisal Yamin ◽  
Sunil Kumar
Keyword(s):  
Experimental Study ◽  
Functional Activity ◽  
Frozen Shoulder ◽  
Group Interventions ◽  
Treatment Results ◽  
Treatment Groups ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Positive Results

OBJECTIVES To compare the effectiveness of Maitland technique (Grade IV) and Mulligan technique for the treatment of frozen shoulders. STUDY DESIGN Experimental Study. STUDY SETTINGS & PARTICIPANTS This study has been conducted at Ziauddin Hospital with 50 volunteers who participated in the study that were equally divided into two groups (pre and post treatment groups). Subjects were randomly assigned to each group. INTERVENTIONS Intervention given to Group A was Maitland Technique (Grade IV) and Group B, Mulligan Technique. OUTCOME MEASURES Functional activity of shoulder is measured by using Shoulder Pain and Disability Index (SPADI) score, Pain is measured by VAS Score, and Range of motion, measured by Goniometer both before and after treatment. RESULTS Both the treatments showed positive results but Mulligan technique was found to be more effective. The total SPADI score was 15.48 before and 11.92 after the Mulligan technique and 15.32 before and 13.16 after the Maitland technique. CONCLUSIONS It is evident that Mulligan technique is more effective for the treatment of frozen shoulder compared to Maitland technique.

scholarly journals Bilirubin Adsorption Versus Plasma Exchange for Hyperbilirubinemia in Patients After Cardiac Surgery: A Retrospective Study

2021 ◽  
Author(s):  
Ke Kan ◽  
He Zhang ◽  
Kai Zhong ◽  
Haitao Zhang ◽  
Zeshi Li ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Treatment Group ◽  
Hospital Mortality ◽  
Plasma Exchange ◽  
Treatment Method ◽  
Circulatory Support ◽  
Mortality And Morbidity ◽  
Treatment Groups ◽  
Before And After ◽  
Bilirubin Adsorption

Abstract Objective: Hyperbilirubinemia after cardiac surgery increases in-hospital mortality and is associated with poor prognosis. Our present study aimed to compare the efficacy of bilirubin adsorption (BA) and plasma exchange (PEX) in patients with hyperbilirubinemia after cardiac surgery.Methods: We retrospectively included patients who underwent BA treatment or PEX treatment due to severe hyperbilirubinemia after cardiac surgery in our center from 2015 to 2020. We collected examinations of urine and liver function before and after treatment and compared the in-hospital mortality and morbidity between two treatment groups. Results: A total of 56 patients were enrolled in this study, 14 patients received BA treatment and 42 patients received PEX treatment. BA group provided a statistically significant reduction in the TBil (p=0.016) and DBil (p=0.036) compared to PEX group. The in-hospital mortality was 85.7% (48/56) in the whole group, BA group had lower mortality than PEX group (71.4% vs. 90.5%, p=0.078). BA group showed better circulatory support, including lower risks of IABP (21.4% vs. 52.4%, p=0.044), ECMO (21.4% vs. 50.0%, p=0.061), re-intubation (64.3% vs. 40.5%, p=0.122) and ventricular arrhythmias (64.3% vs. 45.2%, p=0.217). The in-hospital mortality was still lower in BA treatment group than PEX treatment group (71.4% vs. 100%, p=0.049) in matched cohort.Conclusions: BA treatment had higher removal ability of bilirubin in patients with hyperbilirubinemia and could reduce the mortality and risks of poor clinical outcomes compared to PEX treatment. BA treatment should be considered as an effective treatment method for patients with higher TBil level or Dbil level.

scholarly journals Efficacy of pregabalin versus nortriptyline in the treatment of chronic low backache with radiculopathy: an open label observational study

2019 ◽  
Vol 8 (8) ◽  
pp. 1749
Author(s):  
Annapurna V. T. ◽  
Nivedita Maity ◽  
Ravikumar T. V.
Keyword(s):  
Treatment Group ◽  
Side Effects ◽  
Analogue Scale ◽  
Radicular Pain ◽  
Efficacy And Safety ◽  
Open Label ◽  
Treatment Groups ◽  
Significant Difference ◽  
Reduction Of Pain ◽  
Vas Scores

Background: The efficacy and safety of Pregabalin and Nortriptyline have been proved individually in low backache with radicular pain. However, there are limited number of studies comparing the efficacy of Pregabalin and Nortriptyline in Chronic Low Backache (CLBA) with radicular pain. Hence the present study was designed to determine the efficacy as well as tolerability of Pregabalin in comparison with that of Nortriptyline for reduction of pain in CLBA. The present study was an open label prospective observational study.Methods: Patients with CLBA, 15-60 years of age without specific cause and significant neurological deficit were included in the study. Severity of pain was assessed by Visual Analogue Scale (VAS). Patients were followed up at 2 and 4 weeks and their VAS scores and side effects were noted.Results: Both Pregabalin and Nortriptyline were effective in reducing pain, from baseline to 2 weeks and up to 4 weeks of treatment in chronic low backache with radicular pain, but there was no statistically significant difference between the two treatment groups. The incidences of side effects were less in the Nortriptyline treatment group as compared to Pregabalin.Conclusions: From the results of the present study it can be concluded that both Pregabalin and Nortriptyline were equally effective in the treatment of chronic low backache with radicular pain, but the incidence of adverse effects were more with Pregabalin as compared to Nortriptyline.

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