scholarly journals Asupan protein dan fosfor, rasio fosfor-protein, dan kadar fosfor darah pada pasien gagal ginjal kronis dengan hemodialisis

2012 ◽  
Vol 9 (2) ◽  
pp. 58
Author(s):  
Ahmad Syauqy ◽  
Susetyowati . ◽  
Suhardi .
Keyword(s):  
Protein Intake ◽  
Mineral Metabolism ◽  
Serum Phosphate ◽  
High Protein ◽  
Phosphate Level ◽  
Phosphate Binders ◽  
Serum Phosphate Level ◽  
Protein Ratio ◽  
Phosphate Intake ◽  
High Phosphate

Background: Hyperphosphatemia has become one of the main causes of death in CKD patients on HD. Thus, correction and prevention of hyperphospatemia is a major component in the management of HD patients. High protein diet in HD patients may lead to increased serum phosphate level due to mineral metabolism disorder associated with decreased glomerular filtration rate. In addition, high protein intake often followed by high phosphate intake as high protein foods also contains high phosphate and may cause hyperphosphatemia. Meanwhile, reduction of protein intake to control phosphate level was associated with decreased health and nutritional status in CKD patients. Therefore, appropriate phosphate-protein ratio is essential to provide adequate protein intake and avoid hyperphosphatemia.Objective: To investigate the association between protein and phosphate intake, phosphate-protein ratio and blood phosphate level in CKD patients on routine HD.Method: The study used an analytic observational method with cross sectional design. There were 100 subjects involved in this study. Subject characteristics, protein and phosphate intake, phosphate-protein ratio and intake of phosphate binders were obtained through interview and 3 x24 hour food record. Serum phosphate level was analyzed by inorganic phosphorus quantification method. Food processor was used to analyze the intake of protein and phosphate. Bivariate and multivariate tests with 95% confidence interval were used to analyze the data.Results: Adequate protein intake was observed among 38% subjects, while 46% of them have excess phosphate intake.High phosphate-protein ratio was found in 20% subjects. Most subjects did not take phosphate binders regularly (61%) and have hyperphosphatemia (66%). The average protein intake, phosphate intake, phosphate-protein ratio, and blood phosphate level were 1.1 g/kg/d, 13.5 mg/kg/d, 12.8 mg/g, and 5.6 mg/dl, respectively. Bivariate test showed that there was a significant association between protein intake (p=0.037; RP=2.78), phosphate intake (p=0.005; RP=3.54), phosphate-protein ratio (p=0.045; RP=3.85), and blood phosphate level in CKD patients on routine HD. Multivariate analysis revealed that high phosphate intake and did not consume phosphate binders regularly  were risk factors of hyperphosphatemia (p=0.000; OR=6.543; CI 95%:2.357-18.164 dan p=0.024; OR=3.413; CI 95%:1.179; R2=0.42).Conclusion: Consumtion of low phosphate foods and phosphate binders may reduce the risk of hyperphosphatemia in CKD patients on routine HD.

Effects of serum phosphate level on formation of incisor dentine in hypophosphatemic mice

1996 ◽  
Vol 25 (4) ◽  
pp. 182-187 ◽  
Author(s):  
Y. Masatomi ◽  
Y. Nakagawa ◽  
Y. Kanamoto ◽  
S. Sobue ◽  
T. Ooshima
Keyword(s):  
Serum Phosphate ◽  
Phosphate Level ◽  
Serum Phosphate Level

Prognostic value of serum phosphate level in adult patients resuscitated from cardiac arrest

Resuscitation ◽  
2018 ◽  
Vol 128 ◽  
pp. 56-62 ◽  
Author(s):  
Yong Hun Jung ◽  
Byung Kook Lee ◽  
Kyung Woon Jeung ◽  
Chun Song Youn ◽  
Dong Hun Lee ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Prognostic Value ◽  
Serum Phosphate ◽  
Adult Patients ◽  
Phosphate Level ◽  
Serum Phosphate Level

How do we sense phosphate to regulate serum phosphate level?

2019 ◽  
Vol 38 (1) ◽  
pp. 1-6
Author(s):  
Seiji Fukumoto ◽  
Yuichi Takashi ◽  
Maria K. Tsoumpra ◽  
Shun Sawatsubashi ◽  
Toshio Matsumoto
Keyword(s):  
Serum Phosphate ◽  
Phosphate Level ◽  
Serum Phosphate Level

scholarly journals Relation Between Serum Phosphate Level and Cardiovascular Event Rate in People With Coronary Disease

Circulation ◽  
2005 ◽  
Vol 112 (17) ◽  
pp. 2627-2633 ◽  
Author(s):  
Marcello Tonelli ◽  
Frank Sacks ◽  
Marc Pfeffer ◽  
Zhiwei Gao ◽  
Gary Curhan
Keyword(s):  
Coronary Disease ◽  
Cardiovascular Event ◽  
Event Rate ◽  
Serum Phosphate ◽  
Phosphate Level ◽  
Serum Phosphate Level

Serum phosphate level in burn patients

Burns ◽  
2010 ◽  
Vol 36 (7) ◽  
pp. 1112-1115 ◽  
Author(s):  
Shahriar Loghmani ◽  
Mohammad Reza Maracy ◽  
Reza Kheirmand
Keyword(s):  
Serum Phosphate ◽  
Phosphate Level ◽  
Serum Phosphate Level ◽  
Burn Patients

scholarly journals MgCaCO3Versus CaCO3in Peritoneal Dialysis Patients – a Cross-over Pilot Trial

2015 ◽  
Vol 35 (1) ◽  
pp. 31-34 ◽  
Author(s):  
Baigalmaa Evsanaa ◽  
Irene Liu ◽  
Babak Aliazardeh ◽  
Sara Mahdavi ◽  
Gursarn Bajwa ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Calcium Carbonate ◽  
Pilot Study ◽  
Serum Magnesium ◽  
Pilot Trial ◽  
Magnesium Carbonate ◽  
Serum Phosphate ◽  
Phosphate Binders ◽  
Serum Phosphate Level ◽  
Calcium Magnesium

BackgroundDespite adverse effects such as constipation, vascular calcification, and hypercalcemia, calcium-based salts are relatively affordable and effective phosphate binders that remain in widespread use in the dialysis population. We conducted a pilot study examining whether the use of a combined magnesium/calcium-based binder was as effective as calcium carbonate at lowering serum phosphate levels in peritoneal dialysis (PD) patients.MethodsThis was a cross-over, investigator-masked pilot study in which prevalent PD patients received calcium carbonate alone (200 mg calcium per tablet) or calcium magnesium carbonate (100 mg calcium, 85 mg magnesium per tablet). Primary outcome was serum phosphate level at 3 months. Analysis was as per protocol.ResultsTwenty patients were recruited, 17 completed the study. Mean starting dose was 11.35 ± 7.04 pills per day of MgCaCO3and 9.00 ± 4.97 pills per day of CaCO3. Mean phosphate levels fell from 2.13 mmol/L to 2.01 mmol/L (95% confidence interval (CI): 1.76 – 2.30, p = 0.361) in the MgCaCO3group, and 1.81 mmol/L (95% CI: 1.56 – 2.0, p = 0.026) in the CaCO3alone group. Six (35%) patients taking MgCaCO3and 9 (54%) taking CaCO3alone achieved Kidney Disease Outcomes Quality Initiative (KDOQI) serum phosphate targets at 3 months. Diarrhea developed in 9 patients taking MgCaCO3and 3 taking CaCO3. Serum magnesium exceeded 1.4 mmol/L in 5 patients taking MgCaCO3while serum calcium exceeded 2.65 mmol/L in 3 patients receiving CaCO3. When compared to the initial dose, the prescribed dose at 3 months was reduced by 44% (to 6.41 tablets/day) in the MgCaCO3group and by 8% (to 8.24 pills per day) in the CaCO3alone group.ConclusionCompared with CaCO3alone, the preparation and dose of MgCaCO3used in this pilot study was no better at lowering serum phosphate levels in PD patients, and was associated with more dose-limiting side effects.

scholarly journals Deterioration of Cerebral Oxygenation by Aortic Arch Calcification Progression in Patients Undergoing Hemodialysis: A Cross-Sectional Study

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Kiyonori Ito ◽  
Susumu Ookawara ◽  
Tomohisa Okochi ◽  
Yuichiro Ueda ◽  
Masaya Kofuji ◽  
...  
Keyword(s):  
Aortic Arch ◽  
Cerebral Oxygenation ◽  
Univariate Analysis ◽  
Multivariate Logistic Regression Analysis ◽  
Serum Phosphate ◽  
Phosphate Level ◽  
Serum Phosphate Level ◽  
History Of ◽  
Grade 3 ◽  
Aortic Arch Calcification

Background. Near-infrared spectroscopy revealed that the regional saturation of oxygen (rSO2) in cerebral tissue is lower in hemodialysis (HD) patients than in healthy subjects. However, no study has examined the changes in cerebral oxygenation by aortic arch calcification (AAC) progression in HD patients. Methods. A total of 104 HD patients were divided into four groups by AAC grade determined using chest radiography: 23 patients at grade 0, 24 at grade 1, 30 at grade 2, and 27 at grade 3. Differences in clinical parameters, including cerebral rSO2, among AAC grades were investigated and atherosclerotic parameters affecting cerebral rSO2 values were identified. Results. Cerebral rSO2 significantly decreased as AAC progressed (AAC grade 3 versus grade 0, p<0.01 versus grade 1, p<0.05). Multivariate logistic regression analysis was performed using parameters with p values < 0.20 in univariate analysis between cerebral rSO2 values less than the mean and atherosclerotic parameters. AAC grades 2 and 3, serum phosphate level, and history of smoking were factors associated with the cerebral rSO2 decrease. Conclusions. Cerebral rSO2 significantly decreased as AAC progressed and was independently associated with higher AAC grade, serum phosphate level, and history of smoking.

Sign in / Sign up

Export Citation Format

Share Document