scholarly journals Detection of Urinary Stones at Reduced Radiation Exposure: A Phantom Study Comparing Computed Radiography and a Low-Dose Digital Radiography Linear Slit Scanning System

2009 ◽  
Vol 192 (6) ◽  
pp. W271-W274 ◽  
Author(s):  
Zsolt Szucs-Farkas ◽  
Dev P. Chakraborty ◽  
Harriet C. Thoeny ◽  
Christos Loupatatzis ◽  
Peter Vock ◽  
...  
Keyword(s):  
Radiation Exposure ◽  
Digital Radiography ◽  
Low Dose ◽  
Computed Radiography ◽  
Phantom Study ◽  
Urinary Stones ◽  
Scanning System ◽  
Slit Scanning

scholarly journals A systematic review on the effect of low-dose radiation on hearing

2021 ◽  
Author(s):  
Srikanth Nayak ◽  
Arivudai Nambi ◽  
Sathish Kumar ◽  
P Hariprakash ◽  
Pradeep Yuvaraj ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Low Dose ◽  
Behavioral Symptoms ◽  
National Council ◽  
Low Dose Radiation ◽  
Cochlear Function ◽  
High Frequencies ◽  
Dose Radiation

AbstractNumerous studies have documented the adverse effects of high-dose radiation on hearing in patients. On the other hand, radiographers are exposed to a low dose of ionizing radiation, and the effect of a low dose of radiation on hearing is quite abstruse. Therefore, the present systematic review aimed to elucidate the effect of low-dose ionizing radiation on hearing. Two authors independently carried out a comprehensive data search in three electronic databases, including PUBMED/MEDLINE, CINAHL, and SCOPUS. Eligible articles were independently assessed for quality by two authors. Cochrane Risk of Bias tool was used assess quality of the included studies. Two articles met the low-dose radiation exposure criteria given by Atomic Energy Regulatory Board (AERB) and National Council on Radiation Protection (NCRP) guidelines. Both studies observed the behavioral symptoms, pure-tone hearing sensitivity at the standard, extended high frequencies, and the middle ear functioning in low-dose radiation-exposed individuals and compared with age and gender-matched controls. One study assessed the cochlear function using transient-evoked otoacoustic emissions (TEOAE). Both studies reported that behavioral symptoms of auditory dysfunction and hearing thresholds at extended high frequencies were higher in radiation-exposed individuals than in the controls. The current systematic review concludes that the low-dose ionizing radiation may affect the hearing adversely. Nevertheless, further studies with robust research design are required to explicate the cause and effect relationship between the occupational low-dose ionizing radiation exposure and hearing.

scholarly journals Radiation Dose Reduction in CT Torsion Measurement of the Lower Limb: Introduction of a New Ultra-Low Dose Protocol

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1209
Author(s):  
Gabriel Keller ◽  
Simon Götz ◽  
Mareen Sarah Kraus ◽  
Leonard Grünwald ◽  
Fabian Springer ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Radiation Exposure ◽  
Lower Limb ◽  
Low Dose ◽  
Body Volume ◽  
Reconstruction Algorithms ◽  
Pelvic Radiograph ◽  
Lower Radiation Dose ◽  
Median Total Dose ◽  
Image Reconstruction Algorithms

This study analyzed the radiation exposure of a new ultra-low dose (ULD) protocol compared to a high-quality (HQ) protocol for CT-torsion measurement of the lower limb. The analyzed patients (n = 60) were examined in the period March to October 2019. In total, 30 consecutive patients were examined with the HQ and 30 consecutive patients with the new ULD protocol comprising automatic tube voltage selection, automatic exposure control, and iterative image reconstruction algorithms. Radiation dose parameters as well as the contrast-to-noise ratio (CNR) and diagnostic confidence (DC; rated by two radiologists) were analyzed and potential predictor variables, such as body mass index and body volume, were assessed. The new ULD protocol resulted in significantly lower radiation dose parameters, with a reduction of the median total dose equivalent to 0.17 mSv in the ULD protocol compared to 4.37 mSv in the HQ protocol (p < 0.001). Both groups showed no significant differences in regard to other parameters (p = 0.344–0.923). CNR was 12.2% lower using the new ULD protocol (p = 0.033). DC was rated best by both readers in every HQ CT and in every ULD CT. The new ULD protocol for CT-torsion measurement of the lower limb resulted in a 96% decrease of radiation exposure down to the level of a single pelvic radiograph while maintaining good image quality.

Role of digital tomosynthesis in the context of tuberculosis contact investigation: comparisons with digital radiography

2021 ◽  
pp. 028418512110224
Author(s):  
Jeongha Mok ◽  
Jeong A Yeom ◽  
Su Won Nam ◽  
Jun Mi Yoo ◽  
Ji Won Lee ◽  
...  
Keyword(s):  
Digital Radiography ◽  
Low Dose ◽  
Close Contact ◽  
Correct Diagnosis ◽  
Lower Sensitivity ◽  
Digital Tomosynthesis ◽  
Reference Standard ◽  
Contact Investigation ◽  
Screening Study ◽  
Low Dose Computed Tomography

Background Chest radiography value as a screening tool in those exposed to pulmonary tuberculosis (TB) is reduced by its lower sensitivity to detect small intrapulmonary lesions. Purpose To evaluate the efficacy of digital tomosynthesis (DTS) screening of individuals that had contacted persons with active TB using low-dose computed tomography (CT) as the reference standard methods. Material and Methods This retrospective, community-based screening study of 90 adults who had been in close contact with a TB case was undertaken at our institution. All individuals underwent clinical evaluation, digital radiography (DR), DTS, and low-dose chest CT. Observers assessed and classified DR and DTS images using CT as the reference-standard method. Based on clinical and imaging findings, TB status was classified as normal, latent, minimal, subclinical, and active. Diagnostic performances of DTS and DR for the interpretation of correct diagnosis were calculated. Results The estimated effective doses for DR, DTS, and low-dose CT were 0.01 mSv, 0.1 mSv, and 0.33 mSv, respectively. TB statuses of the 90 individuals were as follows: 62 latent (68.9%); two subclinical (2.2%); and one minimal (1.1%). The sensitivities, specificities, and accuracies of DTS and DR in the interpretation of correct diagnosis were 75.8%, 100%, 91.1% and 48.5%, 96.5%, 78.9%, respectively. Conclusion DTS appears to be superior to DR for the detection of lung lesions in individuals with TB contacts. DTS can offer a reasonable option for TB contact investigation.

Reactive oxygen species in cell responses to toxic agents

2002 ◽  
Vol 21 (2) ◽  
pp. 85-90 ◽  
Author(s):  
L E Feinendegen
Keyword(s):  
Radiation Exposure ◽  
Mammalian Cells ◽  
Low Dose ◽  
X Rays ◽  
Low Dose Radiation ◽  
Cell Responses ◽  
Toxic Agents ◽  
Particle Tracks ◽  
Dose Radiation

This review first summarizes experimental data on biological effects of different concentrations of ROS in mammalian cells and on their potential role in modifying cell responses to toxic agents. It then attempts to link the role of steadily produced metabolic ROS at various concentrations in mammalian cells to that of environmentally derived ROS bursts from exposure to ionizing radiation. The ROS from both sources are known to both cause biological damage and change cellular signaling, depending on their concentration at a given time. At low concentrations signaling effects of ROS appear to protect cellular survival and dominate over damage, and the reverse occurs at high ROS concentrations. Background radiation generates suprabasal ROS bursts along charged particle tracks several times a year in each nanogram of tissue, i.e., average mass of a mammalian cell. For instance, a burst of about 200 ROS occurs within less than a microsecond from low-LET irradiation such as X-rays along the track of a Compton electron (about 6 keV, ranging about 1 μm). One such track per nanogram tissue gives about 1 mGy to this mass. The number of instantaneous ROS per burst along the track of a 4-meV ¬-particle in 1 ng tissue reaches some 70000. The sizes, types and sites of these bursts, and the time intervals between them directly in and around cells appear essential for understanding low-dose and low dose-rate effects on top of effects from endogenous ROS. At background and low-dose radiation exposure, a major role of ROS bursts along particle tracks focuses on ROS-induced apoptosis of damage-carrying cells, and also on prevention and removal of DNA damage from endogenous sources by way of temporarily protective, i.e., adaptive, cellular responses. A conclusion is to consider low-dose radiation exposure as a provider of physiological mechanisms for tissue homoeostasis.

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