scholarly journals The hemodynamical changes on clamping and declamping of the aorta in patients with aortic aneurysm. The comparison of aneurysms of thoracic descending aorta and abdominal aorta.

1986 ◽  
Vol 6 (3) ◽  
pp. 242-247
Author(s):  
SEKISHI KAINUMA
Keyword(s):  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Descending Aorta

scholarly journals Aneurysmectomy for Crawford’s Type-I Thoracoabdominal Aortic Aneurysm using Gelatin Impregnated Woven Vascular Prosthesis under Mild Hypothermic Extracorporeal Circulation: A Video Presentation

2020 ◽  
Vol 4 (02) ◽  
pp. 136-139
Author(s):  
Ujjwal K. Chowdhury ◽  
Sukhjeet Singh ◽  
Niwin George ◽  
Poonam Malhotra Kapoor ◽  
Srikant Sharma ◽  
...  
Keyword(s):  
Aortic Aneurysm ◽  
Thoracic Aorta ◽  
Abdominal Aorta ◽  
Thoracoabdominal Aortic Aneurysm ◽  
Renal Arteries ◽  
Aortic Aneurysms ◽  
Type I ◽  
Descending Thoracic Aorta ◽  
Descending Aorta ◽  
Type Iv

AbstractBased on the risk of ischemic injury to the spinal cord and the risk of renal failure and mortality, Crawford and colleagues classified thoracoabdominal aortic aneurysms into four extents. Type I thoracoabdominal aortic aneurysms involved the descending thoracic aorta proximal to the level of 6th rib to above the renal arteries; type II extends from the proximal descending thoracic aorta above the level of T6 to below the renal arteries; type III extends from below the level of T6 in the descending aorta and a variable extent in the abdominal aorta; type IV thoracoabdominal aortic aneurysm involved the abdominal aorta without involvement of the descending aorta.

Abstract 12726: Crucial Role of Jak2 V617f-positive Myeloproliferative Neoplasm in the Development of Aortic Aneurysm

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Tetsuro Yokokawa ◽  
Tomofumi Misaka ◽  
Yusuke KIMISHIMA ◽  
Kento Wada ◽  
Keiji Minakawa ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Angiotensin Ii ◽  
Aortic Aneurysm ◽  
Mrna Expression ◽  
Abdominal Aorta ◽  
Myeloproliferative Neoplasms ◽  
Myeloproliferative Neoplasm ◽  
Jak2 V617f ◽  
Vascular Complication ◽  
The Impact

Objective: To investigate the impact of hematopoietic JAK2V617F, which causes myeloproliferative neoplasms (MPNs), on the development of aortic aneurysm (AA). Approach and Results: We applied a bone marrow transplantation (BMT) strategy using the donor cells from Jak2 V617F transgenic (JAK2 V617F ) mice into the lethally irradiated apolipoprotein E-deficient mice. To induce the AA formation and progression, the recipient mice (BMT mice) were subjected to continuous angiotensin II infusion. Abdominal aortic diameter in JAK2 V617F -BMT mice was significantly enlarged compared to the control wild-type (WT)-BMT mice in response to angiotensin II. The incidence of abdominal AA was significantly higher in JAK2 V617F -BMT mice than in WT-BMT mice. Hematopoietic JAK2V617F accelerated aortic elastic lamina degradation as well as activation of matrix metalloproteinase (MMP)-2 and MMP-9 in the abdominal aorta. The numbers of CD68 + macrophages and Ly6B.2 + neutrophils and cytokine expressions such as Ccl6 and Tgfb1 were significantly increased in the abdominal aorta of JAK2 V617F -BMT mice accompanied by STAT3 activation. Bone marrow-derived macrophages carrying JAK2V617F showed elevations of both Mmp2 and Mmp9 mRNA expression. Finally, we found that 23% of MPN patients with JAK2 V617F mutation showed the presence of AA and increases in TGFB3 and IL-8 mRNA expression of the peripheral leukocytes. Conclusions: Hematopoietic JAK2V617F was involved in the development of AA through increases in the infiltration of inflammatory cells and MMP activation. Our findings provide a novel feature of vascular complication of AA in MPNs due to constitutive activation of the hematopoietic JAK-STAT pathway.

scholarly journals A Neglected Case of Thoracic Aortic Aneurysm– A Case Report

2015 ◽  
Vol 16 (1) ◽  
pp. 53-55
Author(s):  
Sohely Sultana ◽  
Mohammad Faisal Ibn Kabir ◽  
Tarana Yasmin ◽  
Shyamal KR Roy ◽  
Asish Sarkar ◽  
...  
Keyword(s):  
Chest Pain ◽  
Aortic Aneurysm ◽  
Thoracic Aortic Aneurysm ◽  
Descending Aorta ◽  
X Ray ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Enhanced Ct ◽  
Surgery Department ◽  
Medical University

A 52 year old female reported to surgery department of Bangabandhu Sheikh Mujib Medical University (BSMMU) with dysphasia and exertional chest pain. With detailed history and examination she was diagnosed as a case of epigastric mass and undergone X-ray chest. The report revealed enlarged mediastinal shadow with suspicion of thoracic aortic aneurysm. X-ray chest was followed by contrast enhanced CT scan which revealed a large partially thrombosed aneurysmal dilatation of the aortic arch with sharp kinking (bend) at distal end of aneurysm and beginning of descending aorta. Then the patient was referred to cardiac surgery for immediate management. But the patient refused to have a surgery. Then two months later the patient again presented with chest pain and admitted in DMCH. But the patient died.DOI: http://dx.doi.org/10.3329/jom.v16i1.22405 J MEDICINE 2015; 16 : 53-55

Abdominal aortic aneurysm screening programme

2019 ◽  
Vol 13 (9) ◽  
pp. 430-434
Author(s):  
Ian Peate
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Screening Programme ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Ultrasound Scan ◽  
Abdominal Aneurysm ◽  
Abdominal Aortic ◽  
The Uk

This is the second article in a series of articles regarding screening programmes. In this article, an overview of the abdominal aorta is provided. The article also considers the abdominal aortic aneurysm screening programme. Aortic abdominal aneurysm is described. The majority of abdominal aortic aneurysms are asymptomatic; however, if there are any symptoms, these are explained. All four UK countries offer men aged 65 years and over a screening opportunity using an ultrasound scan, the fundamental aspects of abdominal aortic aneurysm screening programmes is offered. It is emphasised that screening is not mandatory in the UK; the man has a right to decline the invitation to attend any screening programme.

Effective distributed compliance of the canine descending aorta estimated by modified T-tube model

1993 ◽  
Vol 264 (6) ◽  
pp. H1977-H1987 ◽  
Author(s):  
R. Burattini ◽  
K. B. Campbell
Keyword(s):  
Abdominal Aorta ◽  
Renal Arteries ◽  
The Body ◽  
Tube Length ◽  
Model Parameters ◽  
Aortic Compliance ◽  
Pass Filter ◽  
Descending Aorta ◽  
T Tube ◽  
Elastic Tubes

To estimate descending thoracic aortic compliance in anesthetized open-chest dogs, a modified T-tube arterial model was used. This model consists of two uniform and lossless elastic tubes, one representing arteries going toward the head and upper limbs and the other (body tube) representing descending aortic circulation to the trunk and lower limbs. Each tube terminates with a generalized first-order low-pass filter load. Pressure and flow in the ascending aorta and flow in the upper descending aorta were measured and used to estimate model parameters. Using the estimated model parameters, we calculated the pressure waveshape at the termination of the body tube. Comparison of this model-predicted pressure with pressure measured in the abdominal aorta near the origin of renal arteries suggested that the end of the body tube (effective reflecting site of the body circulation) corresponds to this major branching site of the abdominal aorta. To calculate the length of the body tube, we used aortic pulse wave velocity estimated from the measurements of pressure in ascending and abdominal aorta. Calculated body tube length averaged 30.3 +/- 2.8 cm and approximated the measured length (30.6 +/- 3.0 cm) of the aorta from the arch to the region of the origin of renal arteries. Compliance of the body tube averaged 123 +/- 20 x 10(-6) g-1.cm4.s2 and was interpreted as the descending thoracic aortic compliance. The ratio of this compliance to the body tube length gave an estimate of the effective distributed compliance, i.e., the compliance per unit length that would be observed in the absence of tapering. This ratio averaged 4.10 +/- 0.86 x 10(-6) g-1.cm3.s2 and fell in between the values of local aortic compliance independently estimated along the descending thoracic aorta from measurements of pressure and diameter. Thus tube compliance resulted in a physically identifiable property. This property was contrasted with the ill-defined effective compliances of the terminal loads.

scholarly journals Early Morphofunctional Changes in AngII-Infused Mice Contribute to Regional Onset of Aortic Aneurysm and Dissection

2020 ◽  
Vol 57 (6) ◽  
pp. 367-375
Author(s):  
Lydia Aslanidou ◽  
Bram Trachet ◽  
Linda Sasset ◽  
Goran Lovric ◽  
Nikolaos Stergiopulos ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Vascular Reactivity ◽  
Ex Vivo ◽  
Aortic Aneurysms ◽  
Microstructural Damage ◽  
Suprarenal Aorta ◽  
Aortic Aneurysm And Dissection

Aortic aneurysms and dissections are silent and lethal conditions, whose pathogenesis remains incompletely understood. Although angiotensin II (AngII)-infused ApoE−/− mice have been widely used to study aortic aneurysm and dissection, early morphofunctional alterations preceding the onset of these conditions remain unknown. The goal of this study was to unveil early morphofunctional changes underlying the onset of aneurysm and dissection. At 3 days post-AngII infusion, suprarenal abdominal aorta presented significant volumetric dilatation and microstructural damage. Ex vivo assessment of vascular reactivity of the suprarenal dissection-prone aorta and its side branches, showed an endothelial and contractile dysfunctions that were severe in the suprarenal aorta, moderate distally, and absent in the side branches, mirroring the susceptibility to dissection of these different vascular segments. Early and specific morphofunctional changes of the suprarenal aorta may contribute to the regional onset of aortic aneurysm and dissection by exacerbating the biomechanical burden arising from its side branches.

Investigating the Effect of Intraluminal Thrombus in Abdominal Aortic Aneurysm by Computational and Experimental Methods

2009 ◽  
Author(s):  
Florentina Ene ◽  
Carine Gachon ◽  
Patrick Delassus ◽  
Liam Morris
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
High Risk ◽  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Experimental Methods ◽  
Infrarenal Aorta ◽  
Intraluminal Thrombus ◽  
Abdominal Aortic ◽  
Risk Of Rupture

Abdominal aortic aneurysm (AAA) represents an abnormal dilatation and weakening of the abdominal aorta with high risk of rupture. Most aneurysms of the infrarenal aorta possess an asymmetrical fusiform morphology.

scholarly journals IPC24. Aorta Rupture Assay: Comparing the Failure Pressure of Infrarenal Abdominal Aortic Aneurysm and Normal Abdominal Aorta Specimens

2019 ◽  
Vol 69 (6) ◽  
pp. e94-e95
Author(s):  
Vivian C. Gomes ◽  
Madhavan L. Raghavan ◽  
Luiz F. da Silva ◽  
Selene Zyngier ◽  
Gina Silvestre ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Failure Pressure ◽  
Infrarenal Abdominal Aortic Aneurysm ◽  
Abdominal Aortic ◽  
Aorta Rupture
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