scholarly journals A Case of Postoperative Lung Injury Requiring a Large Amount of Fresh Frozen Plasma to Achieve Hemostasis during Open-heart Surgery

2016 ◽  
Vol 36 (3) ◽  
pp. 297-304
Author(s):  
Keiko OKAMURA ◽  
Junko ICHIKAWA ◽  
Mitsuharu KODAKA ◽  
Goro KANEKO ◽  
Mariko ONO ◽  
...  
Keyword(s):  
Lung Injury ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Fresh Frozen Plasma ◽  
Open Heart ◽  
Fresh Frozen ◽  
Frozen Plasma

Universal fresh frozen plasma (Uniplas): a safe product in open-heart surgery

2003 ◽  
Vol 29 (10) ◽  
pp. 1736-1743 ◽  
Author(s):  
Stein Tølløfsrud ◽  
Harald Noddeland ◽  
Jan Ludvig Svennevig ◽  
Gunnar Bentsen ◽  
Tom Eirik Mollnes ◽  
...  
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
Fresh Frozen Plasma ◽  
Open Heart ◽  
Safe Product ◽  
Fresh Frozen ◽  
Frozen Plasma

The Role of Thromboelastography in Directing Blood Product Usage in Infant Open Heart Surgery

2009 ◽  
Vol 4 (5) ◽  
pp. 282-290 ◽  
Author(s):  
Eric N. Mendeloff ◽  
George F. Glenn ◽  
Paul Tavakolian ◽  
Eugene Lin ◽  
Allison Leonard ◽  
...  
Keyword(s):  
Heart Surgery ◽  
Blood Product ◽  
Open Heart Surgery ◽  
Fresh Frozen Plasma ◽  
Blood Component ◽  
Open Heart ◽  
Product Usage ◽  
Blood Component Therapy ◽  
Fresh Frozen

Objective Thromboelastography (TEG) measures the dynamics of clot formation in whole blood and provides data that can guide specific blood component therapy. This study analyzed whether the implementation of TEG affected blood product utilization and overall hemostasis in infants (6 months and younger) undergoing open heart surgery. Methods TEG values measured include R (time to fibrin formation), angle (fibrinogen formation), and MA (platelet function). Blood product usage, TEG values, and operative parameters were collected during surgery on 112 consecutive infants (66 acyanotic) undergoing open heart surgery within the first 6 months of life. Controls consisted of chart data on 70 consecutive patients (57 acyanotic) undergoing the same surgical procedures before implementation of TEG (pre-TEG). Results Using TEG, the pattern of blood product utilization changed. Compared with the pre-TEG era, TEG era patients demonstrated a significant increase in fresh frozen plasma usage intraoperatively (4.74 vs. 1.83 mL/kg; P < 0.001) and reduced postoperative use of platelets (1.69 vs. 3.74 mL/kg; P = 0.006) and cryoprecipitate (0.89 vs. 1.95 mL/kg; P = 0.149). Chest tube drainage was significantly reduced at 1, 2, and 24 hours in the TEG group. TEG angle and MA measurements suggest that fibrinogen and platelets of cyanotic patients are more sensitive to hemodilution than the acyanotic patients. Conclusions TEG allows for proactive, goal-directed blood component therapy with improved postoperative hemostasis in infants undergoing cardiopulmonary bypass.

scholarly journals Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor

2021 ◽  
Vol 9 (6) ◽  
Author(s):  
Charlotte Nielsen Agergaard ◽  
Thure Mors Haunstrup ◽  
Anne‐Louise Fjordside ◽  
John Baech ◽  
Rudi Steffensen ◽  
...  
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Blood Donor ◽  
Fresh Frozen Plasma ◽  
Obstetric Patient ◽  
Fresh Frozen ◽  
Male Blood Donor ◽  
Frozen Plasma

scholarly journals Manajemen Perawatan Pada Pasien Dengan Transfussion Related Acute Lung Injury (TRALI) Di Ruang ICU

2020 ◽  
Vol 13 (2) ◽  
pp. 75-83
Author(s):  
Andi Nur Hidayah
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Fresh Frozen Plasma ◽  
Fresh Frozen ◽  
Frozen Plasma

Transfusi darah dilakukan pada pasien yang mengalami perdahan dengan berbagai penyebab patologis yang mendasari atau terjadinya trauma yang mengakibatkan jumlah sel darah menurun. Transfusi disini termasuk semua jenis produk darah, sel darah merah (PRBC), Fresh Frozen Plasma (FFP), platelet (PLT). Transfusion Related Acute Lung Injury (TRALI) merupakan sindrom fatal yang menyebabkan gangguan pernafasan akut, ini adalah salah satu efek samping transfusi darah yang dapat menyebabkan morbiditas dan mortalitas di ICU. TRALI dapat muncul 6 jam pertama setelah transfusi atau hingga 72 jam selanjutnya. Disini kami membahas tentang 5 laporan kasus TRALI yang terjadi di ICU dengan penanganan suportif yang berfokus pada dukungan pernafasan dengan bantuan oksigen maupun ventilasi mekanik.

scholarly journals Fresh Frozen Plasma Attenuates Lung Injury in a Novel Model of Prolonged Hypotensive Resuscitation

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Amanda M Chipman ◽  
Feng Wu ◽  
Shibani Pati ◽  
Alexander J Burdette ◽  
Jacob J Glaser ◽  
...  
Keyword(s):  
Lung Injury ◽  
Fresh Frozen Plasma ◽  
Hypotensive Resuscitation ◽  
Fresh Frozen ◽  
Novel Model ◽  
Frozen Plasma

Transfusion-related acute lung injury (TRALI) after fresh frozen plasma in a patient with coagulopathy

1996 ◽  
Vol 40 (5) ◽  
pp. 641-644 ◽  
Author(s):  
L. Lindgren ◽  
A. Yli-Hankala ◽  
L. Halme ◽  
S. Koskimies ◽  
R. Orko
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Fresh Frozen Plasma ◽  
Fresh Frozen ◽  
Frozen Plasma
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