scholarly journals The Effects of Direct Hemoperfusion with Polymyxin B-immobilized Fiber and Continuous Hemodiafiltration in a Patient with Septic Shock due to Sigmoid Colon Perforation.

1998 ◽  
Vol 18 (3) ◽  
pp. 291-295
Author(s):  
Toshiaki IKEDA ◽  
Kazumi IKEDA ◽  
Miho USUDA ◽  
Tadashi IWAMOTO ◽  
Kouichirou HAMA ◽  
...  
Keyword(s):  
Septic Shock ◽  
Sigmoid Colon ◽  
Polymyxin B ◽  
Colon Perforation ◽  
Continuous Hemodiafiltration ◽  
Direct Hemoperfusion ◽  
Sigmoid Colon Perforation

scholarly journals Effects of Polymyxin B Hemoperfusion on Septic Shock Patients Requiring Noradrenaline: Analysis of a Nationwide Administrative Database in Japan

2021 ◽  
pp. 1-6
Author(s):  
Kenji Fujimori ◽  
Kunio Tarasawa ◽  
Kiyohide Fushimi
Keyword(s):  
Septic Shock ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Polymyxin B ◽  
Administrative Database ◽  
Control Group ◽  
Continuous Hemodiafiltration ◽  
Significant Survival ◽  
Maximum Daily Dose ◽  
Polymyxin B Hemoperfusion

<b><i>Introduction:</i></b> Polymyxin B hemoperfusion (PMX) reduces endotoxin in septic shock patients’ blood and can improve hemodynamics and organ functions. However, its effects on the reduction of septic shock mortality are controversial. <b><i>Methods:</i></b> Using the Japanese diagnosis procedure combination database from April 2016 to March 2019, we identified adult septic shock patients treated with noradrenaline. This study used propensity score matching to compare the outcome between PMX-treated and non-treated patients. The primary endpoint was 28-day mortality, counting from the day of noradrenaline initiation. The secondary endpoints were noradrenaline-, ventilator-, and continuous hemodiafiltration (CHDF)-free days at day 28. <b><i>Results:</i></b> Of 30,731 eligible patients, 4,766 received PMX. Propensity score matching produced a matched cohort of 4,141 pairs with well-balanced patient backgrounds. The 28-day survival rate was 77.9% in the PMX group and 71.1% in the control group (<i>p</i> &#x3c; 0.0001). Median days of noradrenalin-, CHDF-, and ventilator-free days were 2 days (<i>p</i> &#x3c; 0.0001), 2 days (<i>p</i> &#x3c; 0.0001), and 6 days (<i>p</i> &#x3c; 0.0001) longer in the PMX group than in the control group, respectively. When stratified with the maximum daily dose of noradrenaline, the PMX group showed a statistically significant survival benefit in the groups with noradrenaline dose &#x3c;20 mg/day but not in the noradrenaline group dose ≥20 mg/day. <b><i>Conclusion:</i></b> Analysis of large Japanese databases showed that septic shock patients who received noradrenaline might benefit from PMX treatment.

scholarly journals Sigmoid Colon Perforation Occurred in 12 years after Renal Transplantation

2006 ◽  
Vol 39 (5) ◽  
pp. 620-625 ◽  
Author(s):  
Hiroaki Takeshita ◽  
Takashi Tsuji ◽  
Terumitsu Sawai ◽  
Shigekazu Hidaka ◽  
Shinichi Shibazaki ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Sigmoid Colon ◽  
Colon Perforation ◽  
Sigmoid Colon Perforation

scholarly journals Transmurally migrated gossypiboma rarely posing as surgical site infection: a case report and review of literature

2020 ◽  
Vol 7 (10) ◽  
pp. 3500
Author(s):  
Amrita Gaurav ◽  
Juhi Mishra ◽  
Om Kumari ◽  
Kavita Khoiwal ◽  
Farhanul Huda ◽  
...  
Keyword(s):  
Caesarean Section ◽  
Surgical Site Infection ◽  
Sigmoid Colon ◽  
Primary Repair ◽  
Wound Dehiscence ◽  
Colon Perforation ◽  
Site Infection ◽  
Surgical Sponge ◽  
Ileal Loop ◽  
Sigmoid Colon Perforation

The term gossypiboma is used to describe a retained surgical sponge or gauge after surgery. The clinical features range from being asymptomatic to frank bowel obstruction, perforation and peritonitis. Radiological modalities also do not provide a definite diagnosis. We report a case of a 30-year-old lady who presented to the emergency room with recurrent surgical site infection. She had a history of caesarean section 5 months ago. Following the caesarean section, she developed superficial wound dehiscence which was re-sutured. At the present facility, the lady underwent Computed tomography (CT) scan and was suspected to have a foreign body around the gut. She was planned for an exploratory laparotomy. Upon laparotomy, a large thick-walled ileal loop with some unusual intra luminal mass was found. Dense adhesions were present between the ileal loop and sigmoid colon. Adhesiolysis led to an iatrogenic sigmoid colon perforation, around 2 cm length. On incision over the ileal loop, surgical sponge was retrieved. Ileal loop was resected along with perforated site with end-to-end ileo-ileal anastomosis was done. Primary repair of sigmoid colon perforation was done. Patient was stable in postoperative period. Although rare, gossypiboma should be kept in mind as a differential diagnosis in postoperative cases presenting with recurrent surgical site infection.

Early-onset sigmoid colon perforation during concurrent chemoradiation in a patient with cervical cancer

2004 ◽  
Vol 14 (2) ◽  
pp. 381-383
Author(s):  
H. Lin ◽  
C.-L. Chang ◽  
E.-Y. Huang ◽  
C.-C. Changchien
Keyword(s):  
Cervical Cancer ◽  
Sigmoid Colon ◽  
Concurrent Chemoradiotherapy ◽  
Tissue Injury ◽  
Gynecological Cancer ◽  
Good Condition ◽  
External Beam Radiation ◽  
Colon Perforation ◽  
Beam Radiation ◽  
Sigmoid Colon Perforation

Radiation-induced colon perforation is a rare adverse effect caused by vascular and connective tissue injury to the rectosigmoid colon. It usually occurs a few months to years after radiotherapy for gynecological cancer. Herein, we present a patient who developed sigmoid colon perforation during concurrent chemoradiotherapy for cervical cancer. The patient was a 64-year-old clinical stage IIB woman who received concurrent chemoradiotherapy as a standard treatment. The chemotherapeutic protocol was cisplatin 50 mg/m2 and 5-fluorouracil 4000 mg, starting together with radiotherapy. After the completion of external beam radiation for 4500 cGy, the patient developed sigmoid colon perforation presenting with fecal peritoneum and sepsis. An emergency end ileostomy with resection of entire sigmoid colon was performed and the patient was discharged 3 months later in good condition. Clinicians must be highly suspicious of serious bowel perforation, even if the full dose of radiation has not been completed. Whether or not the chemotherapy was the trigger factor is in need of further clarification.

scholarly journals Sigmoid colon perforation in the patient with granulomatosis with polyangiitis

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Jun Iwabu ◽  
Tsutomu Namikawa ◽  
Hiroyuki Kitagawa ◽  
Toshichika Kanagawa ◽  
Junko Nakashima ◽  
...  
Keyword(s):  
Sigmoid Colon ◽  
Granulomatosis With Polyangiitis ◽  
Colon Perforation ◽  
Sigmoid Colon Perforation
Sign in / Sign up

Export Citation Format

Share Document