scholarly journals Collaborative contributions of basic scientists and clinicians to disease biomarker discovery

2014 ◽  
Vol 58 (1) ◽  
pp. 5-8
Author(s):  
Fumio Nomura
Keyword(s):  
Biomarker Discovery ◽  
Disease Biomarker

scholarly journals Pathway-based subnetworks enable cross-disease biomarker discovery

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Syed Haider ◽  
Cindy Q. Yao ◽  
Vicky S. Sabine ◽  
Michal Grzadkowski ◽  
Vincent Stimper ◽  
...  
Keyword(s):  
Biomarker Discovery ◽  
Disease Biomarker

scholarly journals Characterization of LC-MS based urine metabolomics in healthy subjects across the life span

2020 ◽  
Author(s):  
Xiaoyan Liu ◽  
Xiaoyi Tian ◽  
Qinghong Shi ◽  
Haidan Sun ◽  
Jing Li ◽  
...  
Keyword(s):  
Biomarker Discovery ◽  
High Resolution Mass Spectrometry ◽  
Estrogen Metabolism ◽  
Healthy Children ◽  
Urine Metabolites ◽  
Clinical Cohort ◽  
Disease Biomarker ◽  
Gender And Age ◽  
Urine Metabolomics

AbstractPrevious studies reported that gender and age could influence urine metabolomics, which should be considered in biomarker discovery. As a consequence, for the baseline of urine metabolomics characteristics, it becomes critical to avoid confounding effects in clinical cohort studies. In this study, we provided a comprehensive lifespan characterization of urine metabolomics in a cohort of 348 healthy children and 315 adults aged 1 to 70 years using liquid chromatography coupled with high resolution mass spectrometry. Our results suggested that gender-dependent urine metabolites are much greater in adults than in children. The pantothenate and CoA biosynthesis and alanine metabolism pathways were enriched in early life. Androgen and estrogen metabolism showed high activity during adolescence and youth stages. Pyrimidine metabolism was enriched in the old stage. Based on the above analysis, metabolomic characteristics of each age stage were provided. This work could help us understand the baseline of urine metabolism characteristics and contribute to further studies of clinical disease biomarker discovery.

The role of electrophoresis in disease biomarker discovery

2007 ◽  
Vol 28 (12) ◽  
pp. 1980-1988 ◽  
Author(s):  
Haleem J. Issaq ◽  
Timothy D. Veenstra
Keyword(s):  
Biomarker Discovery ◽  
Disease Biomarker

Disease Biomarker Discovery in Korea

PROTEOMICS ◽  
2006 ◽  
Vol 6 (4) ◽  
pp. 1091-1093
Author(s):  
Young-Ki Paik
Keyword(s):  
Biomarker Discovery ◽  
Disease Biomarker

Application of Metabolomics to Cardiovascular and Renal Disease Biomarker Discovery

2014 ◽  
pp. 279-308
Author(s):  
Gloria Alvarez-Llamas ◽  
Maria G. Barderas ◽  
Maria Posada-Ayala ◽  
Marta Martin-Lorenzo ◽  
Fernando Vivanco
Keyword(s):  
Renal Disease ◽  
Biomarker Discovery ◽  
Disease Biomarker

scholarly journals Proteomic profiling in MPTP monkey model for early Parkinson disease biomarker discovery

2015 ◽  
Vol 1854 (7) ◽  
pp. 779-787 ◽  
Author(s):  
Xiangmin Lin ◽  
Min Shi ◽  
Jeyaraj Gunasingh Masilamoni ◽  
Romel Dator ◽  
James Movius ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Biomarker Discovery ◽  
Proteomic Profiling ◽  
Disease Biomarker ◽  
Monkey Model

Analytical strategies in lipidomics and applications in disease biomarker discovery

2009 ◽  
Vol 877 (26) ◽  
pp. 2836-2846 ◽  
Author(s):  
Chunxiu Hu ◽  
Rob van der Heijden ◽  
Mei Wang ◽  
Jan van der Greef ◽  
Thomas Hankemeier ◽  
...  
Keyword(s):  
Biomarker Discovery ◽  
Disease Biomarker ◽  
Analytical Strategies

Integrative System Biology Strategies for Disease Biomarker Discovery

2012 ◽  
Vol 15 (4) ◽  
pp. 286-298 ◽  
Author(s):  
Haiyuan Zhang ◽  
Hao Hu ◽  
Cao Deng ◽  
Yeona Chun ◽  
Shengtao Zhou ◽  
...  
Keyword(s):  
System Biology ◽  
Biomarker Discovery ◽  
Disease Biomarker ◽  
Integrative System
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