The Island Study Linking Ageing and Neurodegenerative Disease (ISLAND): a Prospective, Online, Public Health Cohort Study Targeting Dementia Risk Reduction (Preprint)

2021 ◽  
Author(s):  
Larissa Bartlett ◽  
Kathleen Doherty ◽  
Maree Farrow ◽  
Sarang Kim ◽  
Edward Hill ◽  
...  
Keyword(s):  
Public Health ◽  
Cohort Study ◽  
Neurodegenerative Disease ◽  
Risk Reduction ◽  
Population Level ◽  
First Year ◽  
Dementia Prevalence ◽  
Dementia Risk ◽  
Health Project ◽  
Health Cohort Study

BACKGROUND Up to 40% of incident dementia is considered attributable to behavioural and lifestyle factors. Given the current lack of medical treatments and the projected increase in dementia prevalence, a focus on prevention through risk reduction is needed. OBJECTIVE The Island Study Linking Ageing and Neurodegenerative Disease (ISLAND) is a long-term prospective, online cohort study with nested interventions. This 10-year public health project aims to increase dementia risk knowledge and promote changes in dementia risk behaviours at individual and population level. METHODS ISLAND participants (target n=10,000) reside in Tasmania, Australia and are aged 50 years or over. Survey data on knowledge, attitudes and behaviours related to modifiable dementia risk factors will be modelled longitudinally with intervention engagement indices, cognitive functioning and blood-based biomarkers. RESULTS In the initial 12 months, 6,410 participants provided baseline data and have been provided with a personalised dementia risk profile, and guidelines for reducing risk, across nine behavioural and lifestyle domains. Within this first year over one quarter of the cohort (27%) undertook the Preventing Dementia massive open online course and 12% enrolled in university study via the Campus intervention. CONCLUSIONS Recruitment targets are feasible and efforts are ongoing to achieve a representative sample. Findings will inform future public health dementia risk reduction initiatives, by showing whether, when and how dementia risk can be lowered through interventions delivered in an uncontrolled, real-world context.

scholarly journals Raising awareness for dementia risk reduction through a public health campaign: a pre-post study

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e041211
Author(s):  
Irene Heger ◽  
Sebastian Köhler ◽  
Martin van Boxtel ◽  
Marjolein de Vugt ◽  
KlaasJan Hajema ◽  
...  
Keyword(s):  
Public Health ◽  
Mass Media ◽  
The Netherlands ◽  
Risk Reduction ◽  
Community Participation ◽  
Behavioural Change ◽  
Population Level ◽  
Public Health Campaign ◽  
Health Campaign ◽  
Dementia Risk

ObjectivesEvaluate the effect of a health promotion campaign aimed at increasing awareness about dementia risk reduction in middle-aged community-dwelling individuals in the Netherlands.DesignA 10-month public health campaign using mass media and community participation, supported by eHealth. Population-level difference in awareness before and after the campaign, including variation between demographic groups, was assessed in two independent cross-sectional samples from the same target population.SettingThe public health campaign was launched in the Province of Limburg, the Netherlands, targeting all inhabitants aged 40–75 years old. Three specific districts within the Province were chosen for an additional community participation approach, in which local stakeholders were invited to support the campaign.ResultsNo pre- (n=590) post- (n=602) difference was observed in people agreeing to the statement that dementia risk reduction is possible (X2(1)=1.27, p=0.260). For the individual lifestyle factors, physical activity (7.6% increase (X2(1)=7.48, p=0.006)) and healthy diet (10.5% increase (X2(1)=12.37, p≤0.001)) were identified more often as being protective against dementia after the campaign. Of all risk/protective factors assessed, cognitive activity was identified most often at both preassessment (79.4%) and postassessment (80.4%), but there was no increase in awareness (X2(1)=0.17, p=0.677). Self-reported exposure to the campaign was associated with greater awareness and motivation for behavioural change (X2(1)=6.52, p=0.011). Compared with mass media only, the addition of community participation resulted in better recognition of campaign material and the eHealth platform.ConclusionsThis study was not able to reach a population-level increase of awareness of dementia risk reduction. Two out of the three lifestyle factors that formed the foundation of the campaign were identified more often after the campaign. Those reported having been exposed to the campaign were more aware and more inclined towards behavioural change.

scholarly journals Football’s InfluencE on Lifelong health and Dementia risk (FIELD): protocol for a retrospective cohort study of former professional footballers

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e028654 ◽  
Author(s):  
Emma R Russell ◽  
Katy Stewart ◽  
Daniel F Mackay ◽  
John MacLean ◽  
Jill P Pell ◽  
...  
Keyword(s):  
Cohort Study ◽  
Neurodegenerative Disease ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Sport Participation ◽  
Disease Incidence ◽  
Sports Participation ◽  
Contact Sport ◽  
Dementia Risk ◽  
Increased Risk

IntroductionIn the past decade, evidence has emerged suggesting a potential link between contact sport participation and increased risk of late neurodegenerative disease, in particular chronic traumatic encephalopathy. While there remains a lack of clear evidence to test the hypothesis that contact sport participation is linked to an increased incidence of dementia, there is growing public concern regarding the risk. There is, therefore, a pressing need for research to gain greater understanding of the potential risks involved in contact sports participation, and to contextualise these within holistic health benefits of sport.Methods and analysisFootball’s InfluencE on Lifelong health and Dementia risk is designed as a retrospective cohort study, with the aim to analyse data from former professional footballers (FPF) in order to assess the incidence of neurodegenerative disease in this population. Comprehensive electronic medical and death records will be analysed and compared with those of a demographically matched population control cohort. As well as neurodegenerative disease incidence, all-cause, and disease-specific mortality, will be analysed in order to assess lifelong health. Cox proportional hazards models will be run to compare the data collected from FPFs to matched population controls.Ethics and disseminationApprovals for study have been obtained from the University of Glasgow College of Medical, Veterinary and Life Sciences Research Ethics Committee (Project Number 200160147) and from National Health Service Scotland’s Public Benefits and Privacy Panel (Application 1718-0120).

834-P: Weight Change and Dementia Risk in Patients with New-Onset Type 2 Diabetes: A Nationwide Cohort Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 834-P
Author(s):  
HYUK-SANG KWON ◽  
SOON JIB YOO ◽  
MIN-KYUNG LEE ◽  
GA EUN NAM
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Weight Change ◽  
Onset Type ◽  
Dementia Risk ◽  
New Onset

PENERAPAN CLUSTERING PADA PENDUDUK YANG MEMPUNYAI KELUHAN KESEHATAN DENGAN DATAMINING K-MEANS

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Nurul Rofiqo ◽  
Agus Perdana Windarto ◽  
Dedy Hartama
Keyword(s):  
Public Health ◽  
Data Mining ◽  
Population Level ◽  
Research Data ◽  
Health Complaints ◽  
Public Health Services ◽  
National Statistics ◽  
Central Java ◽  
Indonesian Population ◽  
The Government

This study aims to utilize Clushtering Algorithm in grouping the number of people who have health complaints with the K-means algorithm in Indonesia. The source of this research data was collected based on the documents of the provincial population which had health complaints produced by the National Statistics Agency. The data used in this study are data from 2013-2017 consisting of 34 provinces. The method used in this research is K-means Algorithm. Data will be processed by clushtering in 3 clushter, namely clusther high health complaints, clusther moderate and low health complaints. Centroid data for high population level clusters 37.48, Centroid data for moderate population level clusters 27.08, and Centroid data for low population level clusters 14.89. So that obtained an assessment based on the population index that has health complaints with 7 provinces of high health complaints, namely Central Java, Yogyakarta, Bali, West Nusa Tenggara, East Nusa Tenggara, South Kalimantan, Gorontalo, 18 provinces of moderate health complaints, and 9 other provinces including low health complaints. This can be an input to the government to give more attention to residents in each region who have high health complaints through improving public health services so that the Indonesian population becomes healthier without health complaints.Keywords: data mining, health complaints, clustering, K-means, Indonesian residents

A Cohort study to compare Admission criteria and Academic performance among preclinical students at The Copperbelt University School of Medicine: complete enumeration (Preprint)

2019 ◽  
Author(s):  
Andrew Mwila
Keyword(s):  
Academic Performance ◽  
Cohort Study ◽  
Clinical Medicine ◽  
Average Score ◽  
First Year ◽  
Admission Criteria ◽  
Biomedical Sciences ◽  
Dental Surgery ◽  
School Of Medicine ◽  
Better Than

BACKGROUND The Copperbelt University is the second public University in Zambia. The School of Medicine has four major programs namely; Bachelor of Medicine and Surgery, Bachelor of Dental Surgery, Bachelor of Clinical Medicine and Bachelor of Biomedical sciences. The Copperbelt University School of Medicine runs a five-year training program for both the BDS and the MBCHB programs. Students are admitted into the Medical school after successfully completing their first year at the Main campus in the School of Natural Sciences with an average of 4 B grades or higher (B grade is a mark of 65 to 74%). OBJECTIVE The study was done to determine the association between admission criteria and academic performance among preclinical students. Hence, the study compares the academic performance among preclinical students admitted into the Bachelor of Dental Surgery and Bachelor of Medicine and Surgery at the Copperbelt University School of Medicine. METHODS This is a retrospective cohort study conducted at Michael Chilufya Sata School of medicine Campus. A pilot study was conducted with 30 BDS and 30 MBCHB students and the obtained information helped determine the sample size. SPSS was used to analyze the data. The study period lasted approximately 7 weeks at a cost of K1621. RESULTS In 2014, there was an improvement in average performance between 2nd and 3rd year for each program. An average score of 15.4 (SD 4.2) was obtained in 3rd year compared to 12.8 (SD 4.9) in 2nd year (p<0.001). Meanwhile, 3rd MB ChB mean score was 12.6 (SD 3.7) compared to 10.7 (SD 3.6) in 2nd years (p<0.05). However, in 2016, both programs, 3rd year mean scores were lower than 2nd year (MB ChB 2nd year mean score was 12.0 (SD 4.3) compared to 3rd year with a mean score of 9.5 (SD 4.5), p<0.001; BDS 2nd year mean score was 10.6 (SD 4.0) compared to 3rd year mean score of 8.2 (SD 3.4), p<0.01. On average MB ChB students performed better than BDS students in all the years (p<0.05), except in 2016 when the results were comparable. CONCLUSIONS Results from the study shows that entry criteria has a correlation to academic performance as students admitted with higher grades perform much better than those with lower grades.

Fidelity and Its Relationship to Implementation Effectiveness, Adaptation, and Dissemination

2017 ◽  
Author(s):  
Jennifer D. Allen ◽  
Rachel C. Shelton ◽  
Karen M. Emmons ◽  
Laura A. Linnan
Keyword(s):  
Public Health ◽  
Treatment Strategies ◽  
Implementation Fidelity ◽  
Population Level ◽  
The United States ◽  
Dissemination And Implementation ◽  
Evidence Based ◽  
Health Gains ◽  
Significant Public Health ◽  
Research Continuum

There is substantial variability in the implementation of evidence-based interventions across the United States, which leads to inconsistent access to evidence-based prevention and treatment strategies at a population level. Increased dissemination and implementation of evidence-based interventions could result in significant public health gains. While the availability of evidence-based interventions is increasing, study of implementation, adaptation, and dissemination has only recently gained attention in public health. To date, insufficient attention has been given to the issue of fidelity. Consideration of fidelity is necessary to balance the need for internal and external validity across the research continuum. There is also a need for a more robust literature to increase knowledge about factors that influence fidelity, strategies for maximizing fidelity, methods for measuring and analyzing fidelity, and examining sources of variability in implementation fidelity.

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