What Makes a Health-Related Answer Popular on Social Q&A Sites: The Case of HPV Vaccine Topic on Zhihu (Preprint)

2021 ◽  
Author(s):  
Jinhui Li ◽  
Han Zheng ◽  
Xu Duan
Keyword(s):  
Hpv Vaccine ◽  
Online Community ◽  
Negative Binomial ◽  
Hpv Vaccination ◽  
Negative Binomial Regression ◽  
Significant Interaction Effect ◽  
Health Community ◽  
Community Organizers ◽  
Health Related ◽  
Response Behaviors

BACKGROUND Social question-and-answer (Q&A) sites have become an important venue for individuals to obtain and share human papillomavirus (HPV) vaccine knowledge. OBJECTIVE The present study aims to examine how different features of an HPV vaccine answer are associated with users’ response behaviors on social Q&A sites. METHODS A total of 2,953 answers and 270 corresponding questions regarding the HPV vaccine were collected from a leading Chinese social Q&A platform, Zhihu. Three types of key features, including content, context, and contributor, were extracted and coded. Negative binomial regression models were employed to examine their impacts on the vote and comment count of an HPV vaccine answer. RESULTS The findings showed that both content length and vividness were positively related to response behaviors of HPV vaccine answers. In addition, compared to answers under the question theme “benefits and risks,” answers under the question theme “vaccination experience” received fewer votes and answers under the theme “news opinions” received more votes but fewer comments. The effects of contributors’ characteristics were also supported, suggesting that answers from a male contributor with more followers and no professional identity would attract more votes and comments from community members. The significant interaction effect between content and context features further showed that long and vivid answers about HPV vaccination experience are more likely to receive users’ votes and comments than those about benefits and risks. CONCLUSIONS The study provides a complete picture of the dynamic mechanisms behind users’ response behaviors towards HPV vaccine answers on social Q&A sites. The results help health community organizers develop better strategies for building and maintaining a vibrant online community for communicating HPV vaccine knowledge.

scholarly journals HPV Vaccine Searches on Pinterest: Before and After Pinterest’s Actions to Moderate Content

2020 ◽  
Vol 110 (S3) ◽  
pp. S305-S311
Author(s):  
Jeanine P. D. Guidry ◽  
Emily K. Vraga ◽  
Linnea I. Laestadius ◽  
Carrie A. Miller ◽  
Aurora Occa ◽  
...  
Keyword(s):  
Hpv Vaccine ◽  
Hpv Vaccination ◽  
Health Belief ◽  
Significant Shift ◽  
Search Results ◽  
Related Information ◽  
Before And After ◽  
Health Related ◽  
Belief Model ◽  
The Health Belief Model

Objectives. To compare how human papillomavirus (HPV) vaccination was portrayed on Pinterest before and after the platform acted to moderate vaccine-related search results to understand (1) what the information environment looked like previously and (2) whether Pinterest’s policy decisions improved this environment in terms of sources and content. Methods. In this quantitative content analysis, we compared 2 samples of 500 HPV vaccine–focused Pinterest posts (“pins”) collected before and after Pinterest’s actions to provide more reliable vaccine-related information. Pins were based on search results and were analyzed using the Health Belief Model. Results. The majority of preaction search results leaned toward vaccine skepticism, specifically focused on perceived vaccine barriers. Few pins were published by public health–related Pinterest accounts. Postaction search results showed a significant shift to HPV vaccination benefits, and the number of pins by government or medical accounts increased. However, the proportion of pins in search results containing HPV content of any type was significantly lower. Conclusions. Pinterest’s efforts to moderate vaccination discussions were largely successful. However, the ban also appeared to limit HPV vaccination search results overall, which may contribute to confusion or an information vacuum.

scholarly journals Evaluating Smart Assistant Responses for Accuracy and Misinformation Regarding Human Papillomavirus Vaccination: Content Analysis Study (Preprint)

2020 ◽  
Author(s):  
John Ferrand ◽  
Ryli Hockensmith ◽  
Rebecca Fagen Houghton ◽  
Eric R Walsh-Buhi
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccine ◽  
Team Member ◽  
Hpv Vaccination ◽  
Average Quality ◽  
Human Papillomavirus Vaccination ◽  
Rigorous Evaluation ◽  
Related Information ◽  
Health Related ◽  
Negative Sentiment

BACKGROUND Almost half (46%) of Americans have used a smart assistant of some kind (eg, Apple Siri), and 25% have used a stand-alone smart assistant (eg, Amazon Echo). This positions smart assistants as potentially useful modalities for retrieving health-related information; however, the accuracy of smart assistant responses lacks rigorous evaluation. OBJECTIVE This study aimed to evaluate the levels of accuracy, misinformation, and sentiment in smart assistant responses to human papillomavirus (HPV) vaccination–related questions. METHODS We systematically examined responses to questions about the HPV vaccine from the following four most popular smart assistants: Apple Siri, Google Assistant, Amazon Alexa, and Microsoft Cortana. One team member posed 10 questions to each smart assistant and recorded all queries and responses. Two raters independently coded all responses (κ=0.85). We then assessed differences among the smart assistants in terms of response accuracy, presence of misinformation, and sentiment regarding the HPV vaccine. RESULTS A total of 103 responses were obtained from the 10 questions posed across the smart assistants. Google Assistant data were excluded owing to nonresponse. Over half (n=63, 61%) of the responses of the remaining three smart assistants were accurate. We found statistically significant differences across the smart assistants (N=103, χ<sup>2</sup><sub>2</sub>=7.807, <i>P</i>=.02), with Cortana yielding the greatest proportion of misinformation. Siri yielded the greatest proportion of accurate responses (n=26, 72%), whereas Cortana yielded the lowest proportion of accurate responses (n=33, 54%). Most response sentiments across smart assistants were positive (n=65, 64%) or neutral (n=18, 18%), but Cortana’s responses yielded the largest proportion of negative sentiment (n=7, 12%). CONCLUSIONS Smart assistants appear to be average-quality sources for HPV vaccination information, with Alexa responding most reliably. Cortana returned the largest proportion of inaccurate responses, the most misinformation, and the greatest proportion of results with negative sentiments. More collaboration between technology companies and public health entities is necessary to improve the retrieval of accurate health information via smart assistants.

scholarly journals Built environment correlates of walking for transportation: Differences between commuting and non-commuting trips

2021 ◽  
Vol 14 (1) ◽  
pp. 1129-1148
Author(s):  
Jixiang Liu ◽  
Jiangping Zhou ◽  
Longzhu Xiao
Keyword(s):  
Built Environment ◽  
Regression Models ◽  
Negative Binomial ◽  
Negative Binomial Regression ◽  
Demographic Variables ◽  
Tobit Regression ◽  
Environment Variables ◽  
Binomial Regression ◽  
Health Related ◽  
Walking For Transportation

As a sustainable mode of travel, walking for transportation has multiple environmental, social, and health-related benefits. In existing studies, however, such walking has rarely been differentiated between commuting and non-commuting trips. Using multilevel zero-inflated negative binomial regression and multilevel Tobit regression models, this study empirically examines the frequency and duration of commuting and non-commuting walking and their correlates in Xiamen, China. It finds that (1) non-commuting walking, on average, has a higher frequency and longer duration than commuting walking; (2) most socio-demographic variables are significant predictors, and age, occupation, and family size have opposite-direction effects on commuting and non-commuting walking; and (3) different sets of built environment variables are correlated with commuting and non-commuting walking, and the built environment collectively influences the latter more significantly than the former. The findings provide useful references for customized interventions concerning promoting commuting and non-commuting walking.

scholarly journals An omega-3 Fatty Acid Enriched Diet Reduces Anxiety-like Behavior While High Dietary Sucrose During Chemotherapy Increases Anxiety-like Behavior in Mice (P14-023-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Kate Ormiston ◽  
Tonya Orchard ◽  
A Courtney DeVries ◽  
Panchitaa Phuwamongkolwiwat ◽  
Jinhui Li ◽  
...  
Keyword(s):  
Negative Binomial ◽  
Negative Binomial Regression ◽  
Significant Negative Correlation ◽  
Saline Group ◽  
Breast Cancer Patients ◽  
Omega 3 ◽  
Significant Interaction Effect ◽  
Significant Difference ◽  
Underlying Mechanisms ◽  
High Sucrose

Abstract Objectives Incidence of anxiety is nearly three times higher in breast cancer patients compared to healthy women, and chemotherapy may increase risk. Chemotherapy-induced neuroinflammation may contribute to anxiety. Omega-3 fatty acids (n-3 FAs), specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), improve symptoms of anxiety in some studies. However, the effects of n-3 FAs on anxiety during chemotherapy have not been examined. We hypothesized that a diet enriched with n-3 FAs and low in sucrose would significantly improve anxiety-like behavior in chemotherapy treated mice. Methods Female, ovariectomized C57BL/6 mice (7–8 weeks old) were randomly assigned to one of four diets: 2% kcal EPA + DHA or no EPA + DHA with low sucrose or high sucrose. After two and four weeks of diets, mice received a saline or chemotherapy injection (9 mg/kg doxorubicin + 90 mg/kg cyclophosphamide), then continued on diets. Seven days after the second injection, mice completed a marble burying test to assess anxiety-like behavior and were sacrificed 10 days later. Significant differences (P < 0.05) were determined using negative binomial regression models. Gene expression of inflammatory cytokines in the hippocampus and cortex was measured using PCR. Spearman correlations assessed associations of cytokines with anxiety. Results Twenty-one % of mice completely buried (i.e., 100% buried) at least one marble; 85% of mice partially buried (>50% but <100% buried) at least one marble. There was a significant n-3 FA effect on number of marbles 100% buried (P = 0.01); fewer marbles were buried by the 2% EPA + DHA group, indicative of less anxiety-like behavior in these mice. There was a significant interaction effect of injection and sucrose on number of marbles 100% buried (P = 0.03); in the chemotherapy group, mice fed low sucrose completely buried fewer marbles than mice fed high sucrose (P < 0.001), but in the saline group, there was no significant difference. There was a significant negative correlation (r = −0.24, P = 0.04) between interleukin-6 in the cortex and number of marbles partially buried. Conclusions Our findings suggest that dietary EPA + DHA reduces, while sucrose and chemotherapy increase, anxiety-like behavior in our mouse model. Future studies should investigate underlying mechanisms. Funding Sources National Cancer Institute.

scholarly journals Evaluating Smart Assistant Responses for Accuracy and Misinformation Regarding Human Papillomavirus Vaccination: Content Analysis Study

10.2196/19018 ◽  
2020 ◽  
Vol 22 (8) ◽  
pp. e19018
Author(s):  
John Ferrand ◽  
Ryli Hockensmith ◽  
Rebecca Fagen Houghton ◽  
Eric R Walsh-Buhi
Keyword(s):  
Human Papillomavirus ◽  
Hpv Vaccine ◽  
Team Member ◽  
Hpv Vaccination ◽  
Average Quality ◽  
Human Papillomavirus Vaccination ◽  
Rigorous Evaluation ◽  
Related Information ◽  
Health Related ◽  
Negative Sentiment

Background Almost half (46%) of Americans have used a smart assistant of some kind (eg, Apple Siri), and 25% have used a stand-alone smart assistant (eg, Amazon Echo). This positions smart assistants as potentially useful modalities for retrieving health-related information; however, the accuracy of smart assistant responses lacks rigorous evaluation. Objective This study aimed to evaluate the levels of accuracy, misinformation, and sentiment in smart assistant responses to human papillomavirus (HPV) vaccination–related questions. Methods We systematically examined responses to questions about the HPV vaccine from the following four most popular smart assistants: Apple Siri, Google Assistant, Amazon Alexa, and Microsoft Cortana. One team member posed 10 questions to each smart assistant and recorded all queries and responses. Two raters independently coded all responses (κ=0.85). We then assessed differences among the smart assistants in terms of response accuracy, presence of misinformation, and sentiment regarding the HPV vaccine. Results A total of 103 responses were obtained from the 10 questions posed across the smart assistants. Google Assistant data were excluded owing to nonresponse. Over half (n=63, 61%) of the responses of the remaining three smart assistants were accurate. We found statistically significant differences across the smart assistants (N=103, χ22=7.807, P=.02), with Cortana yielding the greatest proportion of misinformation. Siri yielded the greatest proportion of accurate responses (n=26, 72%), whereas Cortana yielded the lowest proportion of accurate responses (n=33, 54%). Most response sentiments across smart assistants were positive (n=65, 64%) or neutral (n=18, 18%), but Cortana’s responses yielded the largest proportion of negative sentiment (n=7, 12%). Conclusions Smart assistants appear to be average-quality sources for HPV vaccination information, with Alexa responding most reliably. Cortana returned the largest proportion of inaccurate responses, the most misinformation, and the greatest proportion of results with negative sentiments. More collaboration between technology companies and public health entities is necessary to improve the retrieval of accurate health information via smart assistants.

scholarly journals Characterizing HPV Vaccine Sentiments and Content on Instagram

2019 ◽  
Vol 46 (2_suppl) ◽  
pp. 37S-48S ◽  
Author(s):  
Matthew D. Kearney ◽  
Preethi Selvan ◽  
Michael K. Hauer ◽  
Amy E. Leader ◽  
Philip M. Massey
Keyword(s):  
Hpv Vaccine ◽  
English Language ◽  
Personal Narrative ◽  
Hpv Vaccination ◽  
Personal Narratives ◽  
Misleading Information ◽  
Search Terms ◽  
Health Related ◽  
User Friendly ◽  
The Impact

Background. With its growing popularity, inclusion of image and text, and user-friendly interface, Instagram is uniquely positioned for exploring health behaviors and sources and types of informational exposure related to the human papillomavirus (HPV) vaccine. Aims. To characterize public Instagram posts about the HPV vaccine and quantify the impact of sentiment and context on engagement via likes. Method. Using Netlytic, 3,378 publicly available English-language posts were collected using the search terms “#HPV,” “#HPVVaccine,” and “#Gardasil.” We randomly selected 1,200 posts to content analyze. Our final analytic sample included 360 posts after excluding posts whose links were no longer active ( n = 221) or that were not relevant ( n = 619). Results. A higher proportion of posts were pro-vaccine (55.8%) than anti-vaccine (42.2%). Pro-HPV vaccination posts were liked significantly less than anti-vaccination posts (24 vs. 86 likes; p < .001). More posts contained actionable information/resources (63.9%) than personal narrative elements (36.1%). Less than one in three posts (30.0%) came from health-related sources. Discussion. Pro-vaccine posts were more prevalent on Instagram, and anti-vaccine posts had higher engagement and typically included misleading information about the HPV vaccine. Personal narratives skewed toward anti-vaccine sentiments and most were produced by individual users. Pro-vaccine narratives portrayed individuals who received the vaccine, but provided limited details on vaccine experiences, starkly contrasting with the depth of details in anti-vaccine personal narrative posts. Conclusion. On Instagram, individuals and organizations have an opportunity to promote HPV vaccination by continuing to provide informational resources in addition to creating more narrative-style posts.

Associations of Social Media Use, Patient-centered Communication, and Knowledge with Perceived Human Papillomavirus Vaccine Effectiveness

2020 ◽  
Vol 44 (5) ◽  
pp. 642-651
Author(s):  
Zhaomeng Niu ◽  
Trishnee Bhurosy ◽  
David C. Jeong ◽  
Elliot J. Coups ◽  
Carolyn J. Heckman ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Social Media ◽  
Hpv Vaccine ◽  
Media Use ◽  
Hpv Vaccination ◽  
Vaccine Effectiveness ◽  
Patient Centered ◽  
Social Media Use ◽  
Hpv Knowledge ◽  
Health Related

Objectives: Given the effectiveness of human papillomavirus (HPV) vaccination in preventing cervical cancer and other diseases, as well as the low rates of HPV vaccination in the United States, it is important to examine the determinants of perceived HPV vaccine effectiveness. In this study, we examined the associations between potential factors associated with perceived HPV vaccine effectiveness. Methods: We utilized data (N = 718) from the nationally representative 2017 Health Information National Trends Survey (HINTS). We examined the associations of health-related social media use, patient-centered communication, and HPV knowledge with perceived HPV vaccine effectiveness in preventing cervical cancer. We reported descriptive statistics, and conducted bivariable analyses, multivariable analysis, and mediation analyses. Results: Perceived HPV vaccine effectiveness was associated with sex, age, education, health-related social media use, and HPV knowledge. Additionally, HPV knowledge mediated the associations of health-related social media use and patient-centered communication with perceived HPV vaccine effectiveness. Conclusions: Improving health-related information from social media, patient-centered communication, and HPV knowledge may increase perceived HPV vaccine effectiveness and ultimately, vaccine adoption.

scholarly journals Impact of Depression or Anxiety on Opioid and Benzodiazepine Use in Hospitalized Hematopoietic Stem Cell Transplantation (HSCT) Recipients

Blood ◽  
2018 ◽  
Vol 132 (Supplement 1) ◽  
pp. 4852-4852
Author(s):  
Madiha Iqbal ◽  
Aaron C. Spaulding ◽  
Chanel Wood ◽  
Salman Ahmed ◽  
Prachi Jani ◽  
...  
Keyword(s):  
Stem Cell ◽  
Negative Binomial ◽  
Stem Cell Transplant ◽  
Negative Binomial Regression ◽  
Autologous Stem Cell Transplant ◽  
Cell Transplant ◽  
Depression And Anxiety ◽  
Binomial Regression ◽  
Health Related ◽  
Benzodiazepine Use

Abstract INTRODUCTION: Patients undergoing HSCT are reported to have a high prevalence of depression and anxiety. These comorbid mood disorders have been known to be associated with alteration in pain perception in patients without hematological malignancies. Pharmacological compounds such as opioid and benzodiazepines are frequently used to manage patient symptomology including pain and anxiety. Patients undergoing HSCT are a unique population where the impact of depression and anxiety on opioid and benzodiazepine use has not been well studied. METHODS: The study population consisted of patients who underwent HSCT at a single center for a variety of hematological malignancies from 2015-2018. Opioid and benzodiazepine exposure and dosage was defined in a) Patients who were exposed to opioid including those who were previously exposed and those who were exposed during hospitalization for HSCT b) Patients who were neither exposed to opioid previously, nor during the hospitalization for HSCT. Depression and Anxiety was defined as per PHQ-9 and GAD-7 scales prior to hospital admission. Multivariable analysis was performed to identify differences in opioid status, previous benzodiazepine use, transplant type, Karnofsky score, gender, age, race, and marital status with associated Diazepam Equivalent Daily Dosage (DEDD) (Negative Binomial Regression), and Morphine Milligram Equivalent Daily Dosages (MMEDD) (Logistic and Zero Truncated Negative Binomial Regression). RESULTS: A total of 275 patients underwent HSCT including autologous and allogeneic from 2015-2018. Anxious or depressed HSCT recipients had an increased incidence of higher DEDD with an IRR of 1.69 (95% CI: 1.15, 2.49) compared to those who were neither depressed nor anxious (Figure 1). However, patients who reported anxiety and depression did not have a different DEDD than those not anxious nor depressed. In addition, patients who were not naïve to benzodiazepine use prior to admission had an increased incidence of a higher DEDD [IRR of 2.23 (95% CI: 1.61, 3.05)]. Patients undergoing autologous stem cell transplant had a decreased incidence of receiving a higher DEDD [IRR of 0.65 (95% CI: 0.47-0.90)]. African American and other populations had a decreased incidence of receiving a higher DEDD [IRR of 0.40 (95% CI: 0.27, 0.59)]. Patients receiving higher MMEDD had a higher DEDD incidence [IRR of 1.01 (95% CI: 1.01, 1.02)]. Patients who were both anxious and depressed had increased odds of receiving an opioid [OR of 3.35 (95% CI: 1.62, 6.94)] compared to patients who were neither depressed nor anxious. However, patients who were either depressed or anxious did not have different odds of receiving an opioid compared to those who were neither depressed nor anxious. Patients undergoing autologous stem cell transplant had reduced odds of receiving an opioid [OR of 0.17 (95% CI: 0.07, 0.40)]. Patients with less than normal Karnofsky performance status (<90 on scale of 1-100) had an increased incidence of receiving a higher MMEDD [IRR of 2.34 (95% CI: 1.07, 5.12)] when modeled by Zero Truncated Negative Binomial Regression. Finally, HSCT recipients who were both anxious and depressed had reduced odds of being naïve to opioids [OR0.31 (95% CI: 0.15, 0.67)] compared to recipients who were neither depressed nor anxious. New opioid users had reduced odds of receiving a greater MMEDD [OR of 0.98 (95% CI: 0.96, 0.99)] when compared to previous users. In addition, autologous stem cell transplant recipients had reduced odds of receiving greater MMEDD compared to allogeneic transplant recipients (OR 0.33, 95% CI: 0.16, 0.66). CONCLUSION: Comorbid depression and /or anxiety impact opioid and benzodiazepine use in patients undergoing HSCT. The presence of these comorbid conditions and their association with increased use of opioids and benzodiazepines can also affect various health related outcomes. Larger studies are needed to fully understand the potential impact of this association on health related outcomes. Figure 1. Figure 1. Disclosures Kharfan-Dabaja: Incyte Corp: Speakers Bureau; Alexion Pharmaceuticals: Speakers Bureau; Seattle Genetics: Speakers Bureau. Ailawadhi:Amgen: Consultancy; Pharmacyclics: Research Funding; Celgene: Consultancy; Janssen: Consultancy; Takeda: Consultancy.

HPV VACCINE AND CERVICAL CANCER

2011 ◽  
pp. 108-115
Author(s):  
Vu Quoc Huy Nguyen
Keyword(s):  
Cervical Cancer ◽  
Relative Risk ◽  
Hpv Vaccine ◽  
Hpv Vaccination ◽  
Preventive Strategy ◽  
Protective Effects ◽  
Papilloma Virus ◽  
Vaccine Trials ◽  
Close Relationship ◽  
The Relationship

Persistent infection with high-risk Human Papilloma Virus (HPV) has been identified as the causal factor of cervical cancer, with relative risk up to 300-400 folds. This very close relationship leads to the preventive strategy of vaccination against HPV infections and HPV-related lesions. The article describes molecular and immunologic characteristics of HPV, currently available HPV vaccines and its protective effects; the relationship between HPV vaccination and cervical cancer screening, and an introduction to therapeutic HPV vaccine trials.

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