Comparison of anti-microbial efficacy of Calcipex and Metapex in endodontic treatment of chronic apical periodontitis (Preprint)

2020 ◽  
Author(s):  
Momina Anis Motiwala ◽  
Saqib Habib ◽  
Robia Ghafoor ◽  
Seema Irfan
Keyword(s):  
Bacterial Culture ◽  
Apical Periodontitis ◽  
T Test ◽  
Endodontic Treatment ◽  
Microbial Culture ◽  
Routine Procedure ◽  
Canal System ◽  
Colony Forming Unit ◽  
Root Canal System ◽  
Level Of Significance

BACKGROUND Various intracanal medicaments have been used in cases of chronic apical periodontitis for appropriate disinfection of the root canal system to eliminate microbes specially from the inaccessible areas. Caclcium Hydroxide (CH) is the most common intracanal medicament available in various forms, but its effectiveness with or without iodoform using microbial culture is unknown. OBJECTIVE To compare the anti-microbial efficacy of Calcipex and Metapex in endodontic treatment of teeth presenting with chronic apical periodontitis METHODS 60 single rooted teeth of patients with diagnosis of chronic apical periodontitis were selected and the canals were debrided chemo-mechanically. The patients were randomized into two groups: Calcipex and Metapex. The first sample (S1) for bacterial culture was taken before placement of intracanal medicament and the second sample (S2) was taken after 7 days, before final obturation from the canal and sent to lab for culture. Colony Forming Unit (CFU) will be evaluated. Paired t-test will be used to assess difference bet¬ween antimicrobial efficacies within the group of medicaments. Independent sample t-test will be used to assess antimicrobial efficacies between groups. Level of significance will be kept at 0.05. RESULTS The results wil be shared upon completion of study. CONCLUSIONS There is no risk involved in this study as the study is based on routine procedure of endodontic treatment. It will be a benefit for future patients which will help us to decide which intracanal medicament is more effective to use in infected canals. CLINICALTRIAL NCT04336709

scholarly journals Comparison of antimicrobial efficacy of Calcipex and Metapex in endodontic treatment of chronic apical periodontitis: a randomised controlled trial study protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e048947
Author(s):  
Momina Anis Motiwala ◽  
Saqib Habib ◽  
Robia Ghafoor ◽  
Seema Irfan
Keyword(s):  
Controlled Trial ◽  
Bacterial Load ◽  
Apical Periodontitis ◽  
T Test ◽  
Endodontic Treatment ◽  
University Hospital ◽  
Annual Reports ◽  
Antimicrobial Efficacy ◽  
Ethical Review ◽  
Microbial Culture

IntroductionVarious intracanal medicaments have been used in cases of chronic apical periodontitis for appropriate disinfection of the root canal system to eliminate microbes especially from the inaccessible areas. Calcium hydroxide is the most common intracanal medicament available in various forms, but its effectiveness with or without iodoform using microbial culture is unknown. Therefore, our aim is to compare the antimicrobial efficacy of Calcipex and Metapex in endodontic treatment of teeth presenting with chronic apical periodontitis by assessing the bacterial load reduction.Method and analysis60 single rooted teeth of patients with diagnosis of chronic apical periodontitis will be selected and the canals debrided chemomechanically. The patients will be randomised into two groups: Calcipex and Metapex. The first sample (S1) for bacterial culture will be taken before placement of intracanal medicament and the second sample (S2) will be taken after 7 days, before final obturation from the canal and sent to lab for culture. Colony-forming unit will be evaluated. Paired t-test will be used to assess difference between antimicrobial efficacies within the group of medicaments. Independent sample t-test will be used to assess antimicrobial efficacies between groups. Level of significance will be kept at 0.05.Ethics and disseminationApproval from Aga Khan University Hospital Ethical review committee is taken. Findings will be reported according to the Standard Protocol Items for Randomised Trials guidelines. Research findings will be disseminated through annual reports, peer-reviewed journals and conferences.Trial registration numberNCT04336709.

scholarly journals COMPARATIVE EFFECTIVENESS OF TREATMENT OF CHRONIC APICAL PERIODONTITIS ON THE BASIS OF DENSITOMETRIC AND MICROBIOLOGICAL RESEARCH METHODS

2019 ◽  
Vol 15 (2) ◽  
pp. 17-24 ◽  
Author(s):  
Лариса Герасимова ◽  
Larisa Gerasimova ◽  
Алина Юсупова ◽  
Alina Yusupova ◽  
Ирина Усманова ◽  
...  
Keyword(s):  
Diode Laser ◽  
Root Canal ◽  
Laboratory Data ◽  
Apical Periodontitis ◽  
Endodontic Treatment ◽  
Canal System ◽  
Periodontal Tissues ◽  
Complex Anatomy ◽  
Group I ◽  
Root Canal System

Relevanct of the research topic. One of the possible causes of apical periodontitis is the infectious inflammatory process of the periapical periodontal tissues. The microflora of the root canal system is represented by various microorganisms, among which streptococci, enterococci and staphylococci most often prevail. The complex anatomy of the root canal system ensures the growth and reproduction of microorganisms, and the endodontic treatment does not always contribute to their qualitative and quantitative reduction. Purpose ― study of the effectiveness of endodontic treatment of chronic apical periodontitis in the near and long term. Methods. We observed 110 patients aged 20 to 30 years with apical periodontitis, bone density analysis and microbiological examination of the contents of the root canal. Depending on the obtained clinical and laboratory data, the patients were divided into two clinical groups: in group I endodontic treatment of 55 teeth was carried out according to the scheme developed by us; in group II — 55 teeth using the standard method of treatment. Results. In endodontic treatment of chronic apical periodontitis, treatment of the root canal system with a diode laser promotes better decontamination of the microflora. Coal mining introduction into the root canal system and in the region of the transition folds of the platelet autoplasma leads to an increase of the reparative process in the periapical region (p≤0.05). Summary. The inclusion in the Protocol of endodontic treatment of apical periodontitis of treatment of the root canal system with a diode laser and injection of platelet autoplasm is a more effective method of treatment in comparison with the traditional one.

scholarly journals Inspection of the Microbiota in Endodontic Lesions

2019 ◽  
Vol 7 (2) ◽  
pp. 47 ◽  
Author(s):  
Mario Dioguardi ◽  
Giovanni Di Gioia ◽  
Gaetano Illuzzi ◽  
Claudia Arena ◽  
Vito Carlo Alberto Caponio ◽  
...  
Keyword(s):  
Enterococcus Faecalis ◽  
Root Canal ◽  
Scientific Literature ◽  
Bacterial Species ◽  
Primary Objective ◽  
Endodontic Treatment ◽  
Canal System ◽  
Resistant Species ◽  
Carious Lesions ◽  
Root Canal System

The primary objective of endodontic therapy is to create a biologically acceptable environment within the root canal system that allows for the healing and maintenance of the health of the peri-radicular tissue. Bacteria are one of the main causes of pulp problems, and they have different methods of penetrating and invading the endodontic space such as through carious lesions, traumatic pulp exposures, and fractures. The types of bacteria found range from facultative anaerobes to aerobes, up to the most resistant species able to survive in nutrient-free environments; the bacterial species Enterococcus faecalis belongs to this last group. Enterococcus faecalis is considered one of the main causes of recurring apical periodontal lesions following endodontic treatment, with persistent lesions occurring even after re-treatment. The review presented in this paper was performed in accordance with the PRISMA protocol and covers articles from the related scientific literature that were sourced from PubMed, Scopus, and Google Scholar using the following terms as keywords: “endodontic treatment”, “endodontic bacteria”, “microbial endodontic”, and “endodontic failure”. Only the articles considered most relevant for the purposes of this paper were read in full and taken into consideration for the following review. The results show that Enterococcus faecalis, Actinomycetes, and Propionibacterium propionicum are the species most frequently involved in persistent radicular and extra-radicular infections.

scholarly journals One versus two visits of endodontic treatment on teeth with apical periodontitis

2016 ◽  
Vol 1 (2) ◽  
pp. 299
Author(s):  
Juni Jekti Nugroho
Keyword(s):  
Root Canal ◽  
Treatment Decision ◽  
Apical Periodontitis ◽  
Endodontic Treatment ◽  
Treatment Decision Making ◽  
Tissue Healing ◽  
Absolute Measure ◽  
Root Canal System ◽  
The One ◽  
Dental Professionals

The microbiological purpose of teeth endodontic treatment with apical periodontitis is to reduce microbes in order to achieve periradicular tissue healing and to prevent microbes recolonized. These are obtained by antimicrobial measures, including chemo-mechanical procedures and intra-canal medication, with root canal obturation steps. One of the problems in endodontic is the planning consideration to give treatment with one or two visits. Performing intra-appointment medication is an absolute measure to promote disinfection and successful treatment. Another purpose of this paper is to provide a reference about one or two visit of endodontic treatment decision making for dental professionals. Root canal system on teeth with apical periodontitis treated in two visits endodontic and calcium hydroxide as the intra-appointment medication achieved better microbiological status than the one treated in one visit endodontic.

scholarly journals FREQUENT PROCEDURAL ERRORS AND STRUCTURAL COMPLICATIONS ON ENDODONTICAL TREATED TEETH

2021 ◽  
Vol 67 (2) ◽  
pp. 101-106
Author(s):  
Sanziana Adina Scarlatescu ◽  
◽  
Irina Gheorghiu ◽  
George Nicola ◽  
Andrei O. Al Aloul ◽  
...  
Keyword(s):  
Root Canal ◽  
Technological Progress ◽  
Endodontic Treatment ◽  
Root Canal Treatment ◽  
Canal System ◽  
Root Canals ◽  
Hard Tissues ◽  
Root Canal System

The objectives of root canal treatment are to prevent the apical parodontitis, to heal the acute or cronic apical periodontits and to maintain the results, keeping the teeth on the arch in a functional stage. Thus, accuratelly elimination of soft and hard tissues (cleaning and shaping of the root canal system), disinfection and complete, homogeneous and tridimensional filling of the root canal system are very important to successful endodontic treatment. Modern concepts in endodontic treatment rely on technological progress and therefore many cases are successfully fulfilled, but the practitioner may be put in front of procedural erorrs both during and after endodontic treatment. Apical blockage, ledging, zipping, stripping, perforations in the floor of the pulp canal chamber or root canals perforations are the most common errors, but in many clinical situations they can be prevented and even surpassed once happened.

scholarly journals Assessment of the results of endodontic treatment of teeth

2020 ◽  
Vol 18 (1) ◽  
pp. 27-30
Author(s):  
S. N. Razumova ◽  
A. S. Brago ◽  
Haydar Barakat ◽  
L. M. Khaskhanova ◽  
R. M. Bragunova
Keyword(s):  
Root Canal ◽  
Endodontic Treatment ◽  
Canal System ◽  
High Quality ◽  
Endodontically Treated Teeth ◽  
Root Canals ◽  
Mandibular Molars ◽  
Dental Patient ◽  
Manual Skills ◽  
Root Canal System

The success of endodontic treatment depends on many factors. The most important of them are the knowledge and manual skills of the dentist.Materials and methods. We analyzed the condition of teeth after endodontic treatment in 300 patients aged 20 to 70 years. Were studied 300 images of CBCT, the number of treated teeth and the number of cases of unsuccessful endodontic treatment was analyzed.Results. According to CBCT data, high-quality obturation of the root canal system was observed in 1335 (75%) endodontically treated teeth. The reasons for successful endodontic treatment are under-sealing of the root canal (16%), removal of material beyond the apex (5.6%), and missed root canals (3.4%).Conclusion. Clinical dental patient examination revealed that maxillary and mandibular molars most often undergo endodontic treatment.

The Apical Root Canal System of Teeth with Posttreatment Apical Periodontitis: Correlating Microbiologic, Tomographic, and Histopathologic Findings

2020 ◽  
Vol 46 (9) ◽  
pp. 1195-1203 ◽  
Author(s):  
José F. Siqueira ◽  
Henrique S. Antunes ◽  
Alejandro R. Pérez ◽  
Flávio R.F. Alves ◽  
Ibrahimu Mdala ◽  
...  
Keyword(s):  
Root Canal ◽  
Apical Periodontitis ◽  
Canal System ◽  
Root Canal System ◽  
Histopathologic Findings ◽  
Posttreatment Apical Periodontitis
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