Health impacts and characteristics of deprescribing interventions in older adults: a protocol of a systematic review and meta-analysis. (Preprint)

2020 ◽  
Author(s):  
Zoé Tremblay ◽  
David Mumbere-Bamusemba ◽  
Danielle Laurin ◽  
Caroline Sirois ◽  
Daniela Furrer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Health Outcomes ◽  
Grey Literature ◽  
Life Outcomes ◽  
Bottom Line ◽  
Quality Of Life Outcomes ◽  
Effective Interventions ◽  
The Impact

BACKGROUND Deprescribing, a relatively recent concept, has been proposed as a promising solution to the growing issues of polypharmacy and use of medications of questionable benefit among older adults. However, little is known about the health outcomes of deprescribing interventions. OBJECTIVE This study aims to contribute to the knowledge on deprescribing by addressing two specific objectives: 1) describe the impact of deprescribing in adults’ ≥60 years on health outcomes or quality of life; and 2) determine the characteristics of effective interventions in deprescribing. METHODS Primary studies targeting three concepts (older adults, deprescribing, and health/quality of life outcomes) will be included in the review. The search will be performed using key international databases (MEDLINE, EMBASE, CINAHL, Ageline, PsycInfo) and a special effort will be made to identify grey literature. Two reviewers will independently screen the articles, extract the information and evaluate the quality of the selected studies. If methodologically feasible, meta-analyses will be performed for groups of intervention studies reporting on deprescribing interventions for similar medications, used for similar or identical indications and reporting on similar outcomes (for example benzodiazepines used against insomnia and reporting on quality of sleep or quality of life). Alternatively, results will be presented in bottom-line statements (Objectives 1) and a matrix outlining effective interventions (Objective 2). RESULTS The knowledge synthesis may be limited by the availability of high-quality, clinical trials on deprescribing and its outcomes in older adults. Additionally, analyses will likely be affected by studies on the deprescribing of different types of molecules within the same indication, e.g. different pharmacological classes and medications to treat hypertension, and different measures of health and quality of life outcomes for the same indication. CONCLUSIONS Deprescribing becomes more widespread, therefore knowledge on its effects on health are needed. CLINICALTRIAL CRD42015020866

scholarly journals Health Impacts and Characteristics of Deprescribing Interventions in Older Adults – a Protocol of a Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Zoé Tremblay ◽  
Martine Marcotte ◽  
David Mumbere-Bamusemba ◽  
Danielle Laurin ◽  
Daniela Furrer Soliz-Urrutia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Health Outcomes ◽  
Grey Literature ◽  
Life Outcomes ◽  
Bottom Line ◽  
Quality Of Life Outcomes ◽  
Effective Interventions ◽  
The Impact

Abstract BackgroundDeprescribing, a relatively recent concept, has been proposed as a promising solution to the growing issues of polypharmacy and use of medications of questionable benefit among older adults. However, little is known about the health outcomes of deprescribing interventions. This study aims to contribute to the knowledge on deprescribing by adressing two specific objectives: 1) describe the impact of deprescribing in adults’ ≥60 years on health outcomes or quality of life; and 2) determine the characteristics of effective interventions in deprescribing.MethodsPrimary studies targeting three concepts (older adults, deprescribing, and health/quality of life outcomes) will be included in the review. The search will be performed using key international databases (MEDLINE, EMBASE, CINAHL, Ageline, PsycInfo) and a special effort will be made to identify grey literature. Two reviewers will independently screen the articles, extract the information and evaluate the quality of the selected studies. If methodologically feasible, meta-analyses will be performed for groups of intervention studies reporting on deprescribing interventions for similar medications, used for similar or identical indications and reporting on similar outcomes (for example benzodiazepines used against insomnia and reporting on quality of sleep or quality of life). Alternatively, results will be presented in bottom-line statements (Objectives 1) and a matrix outlining effective interventions (Objective 2).DiscussionThe knowledge synthesis may be limited by the availability of high-quality, clinical trials on deprescribing and its outcomes in older adults. Additionally, analyses will likely be affected by studies on the deprescribing of different types of molecules within the same indication, e.g. different pharmacological classes and medications to treat hypertension, and different measures of health and quality of life outcomes for the same indication.Systematic Review Registration Number: CRD42015020866

scholarly journals Resilience support to enhance positive health outcomes for police officers in five Anglosphere nations: a scoping review protocol

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e038895
Author(s):  
Audrey Steenbeek ◽  
Chris Giacomantonio ◽  
Arlene Brooks ◽  
Camilla Holmvall ◽  
Ziwa Yu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Health Outcomes ◽  
Scoping Review ◽  
Police Officers ◽  
Grey Literature ◽  
Life Outcomes ◽  
Global Business ◽  
Quality Of Life Outcomes

IntroductionLaw enforcement involves exposure to threatening situations and traumatic events that place police officers at risk for negative physical and mental health outcomes. Resilience support, among other elements of training, may help mitigate these risks, yet little is known about which aspects of resilience support help officers achieve better health and quality of life outcomes.Methods and analysisThis review will consider all literature that examines the links between resilience support, physical/mental health and quality of life outcomes for police officers in five Anglosphere nations: Canada, the USA, Australia, New Zealand and the UK. This review will include all literature (including those that show null or negative links) involving any public policing agency that has a formal rank structure and includes a localized, uniformed emergency response function. Resilience support may include, but is not limited to: tools, policies, models, frameworks, programmes and organizational features that seek to promote positive, physical/mental health and quality of life outcomes at three levels of resilience: (1) readiness and preparedness, (2) response and adaptation, (3) recovery and adjustment. Peer reviewed and grey literature examining resilience support since 2000 that focuses on police officers are eligible for inclusion. Databases/sources to be searched will include: PsycINFO, Academic Search Premier, CINAHL, Public Affair Index, Campbell Collaboration, ProQuest Dissertations and Theses Global, Business Source Complete, Scopus and Google. Retrieval of full-text, English-language studies (and other literature), data extraction, data synthesis and data mapping will be performed independently by two reviewers, following Joanna Briggs Institute methodology.Ethics and disseminationEthics approval is not required for this scoping review, and the literature search will start in November 2020 or upon acceptance of this protocol. The findings of the scoping review will be available [April 2021] and will be published in a peer reviewed journal.

The Impact of the Senior Companion Program on Quality of Life Outcomes for Frail Older Adults and Their Families

2004 ◽  
Vol 22 (4) ◽  
pp. 1-26 ◽  
Author(s):  
Donna J. Rabiner ◽  
Scott Scheffler ◽  
Elizabeth Koetse ◽  
Jennifer Palermo ◽  
Elizabeth Ponzi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Life Outcomes ◽  
Frail Older Adults ◽  
Quality Of Life Outcomes ◽  
The Impact

THE IMPACT OF CANCER TREATMENT ON QUALITY OF LIFE OUTCOMES FOR PATIENTS WITH LOCALIZED PROSTATE CANCER

2001 ◽  
Vol 166 (5) ◽  
pp. 1804-1810 ◽  
Author(s):  
CONSTANCE G. BACON ◽  
EDWARD GIOVANNUCCI ◽  
MARCIA TESTA ◽  
ICHIRO KAWACHI
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Cancer Treatment ◽  
Localized Prostate Cancer ◽  
Life Outcomes ◽  
Quality Of Life Outcomes ◽  
The Impact

A Randomized Trial of Weighted Vest Use in Ambulatory Older Adults: Strength, Performance, and Quality of Life Outcomes

2000 ◽  
Vol 48 (3) ◽  
pp. 305-311 ◽  
Author(s):  
Gail A. Greendale ◽  
George J. Salem ◽  
Jean T. Young ◽  
Mark Damesyn ◽  
Michael Marion ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Randomized Trial ◽  
Life Outcomes ◽  
Strength Performance ◽  
Quality Of Life Outcomes ◽  
Weighted Vest
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