scholarly journals Behavioral intention to receive self-financed and free COVID-19 vaccination among Chinese factory workers who resumed work during the pandemic: cross-sectional online survey (Preprint)

2020 ◽  
Author(s):  
Kechun Zhang ◽  
Yuan Fang ◽  
He Cao ◽  
Hongbiao Chen ◽  
Tian Hu ◽  
...  

BACKGROUND COVID-19 vaccines would become available in China very soon. A timely understanding of community responses to the forthcoming COVID-19 vaccines would be important. OBJECTIVE This study investigated prevalence of and factors associated with behavioral intention to receive self-financed and free COVID-19 vaccination among Chinese factory workers who resumed work during the pandemic. Behavioral intention to reduce compliance with some personal preventive measures after receiving COVID-19 vaccination was also investigated. METHODS Participants were full-time employees aged ≥18 years who had resumed work in factories in Shenzhen. Factory workers in Shenzhen are required to receive physical examination once a year. Eligible workers attending six designated physical examination sites were invited to complete an online survey during September 1-7, 2020. Out of 2653 eligible factory workers being approached, 2053 (77.4%) completed the online survey. Multivariate logistic regression models were fitted. RESULTS The prevalence of behavioral intention to receive COVID-19 vaccination was 66.6% (n=1368, conditional on 80% vaccine efficacy and market rate) and 80.6% (n=1551, conditional on 80% vaccine efficacy and free vaccines), respectively. After adjusting for significant background characteristics, positive attitudes toward COVID-19 vaccination (AOR 1.20, 95%CI 1.15-1.25 & AOR 1.26, 95%CI 1.20-1.32), perceived significant others supporting COVID-19 vaccination uptake (AOR 1.44, 95%CI 1.32-1.56 & AOR 1.40, 95%CI 1.27-1.53), and perceived behavioral control to take up COVID-19 vaccination (AOR 1.51, 95%CI 1.32-1.73 & AOR 1.31, 95%CI 1.12-1.54) were positively associated with both dependent variables. Regarding social media influence, higher frequency of exposure to positive information related to COVID-19 vaccination was associated with higher intention to receive COVID-19 vaccination at market rate (AOR 1.54, 95%CI 1.39-1.70) or receive free vaccination (AOR 1.53, 95%CI 1.36-1.72). Higher self-reported compliance with facemask wearing in workplace (AOR: 1.25, 95%CI 1.00-1.55 & AOR 1.67, 95%CI 1.24-2.24) and other public spaces (AOR 1.85, 95%CI 1.46-2.34 & AOR 1.34, 95%CI 1.01-1.77), hand hygiene (AOR 1.52, 95%CI 1.20-1.94), and avoiding social/meal gathering (AOR 1.23, 95%CI 1.02-1.49 & AOR 1.60, 95%CI 1.27-2.01) and crowed place (AOR 1.26, 95%CI 1.04-1.53 & AOR 1.79, 95%CI 1.42-2.25) were also positively associated with one or both dependent variables. Number of COVID-19 preventive measures implemented by the factory were positively associated with intention to receive COVID-19 vaccination under both scenarios (AOR 1.08, 95%CI 1.04-1.12 & AOR 1.07, 95%CI 1.03-1.12). The prevalence of behavioral intention to reduce frequency of facemask wearing, sanitizing hands, and avoiding social gathering/crowed places after receiving COVID-19 vaccination was 34.5% (n=708), 32.9% (n=675), and 28.0% (n=575), respectively. CONCLUSIONS Factory workers in China reported a high behavioral intention to receive COVID-19 vaccination. The Theory of Planned Behavior is a useful framework to guide the development of future campaigns promoting COVID-19 vaccination. However, risk compensation was a concern and should be addressed during COVID-19 vaccination promotion.

2021 ◽  
Vol 9 ◽  
pp. 251513552110158
Author(s):  
Danielle Tully ◽  
Carrie L. Griffiths

The objective of this manuscript was to review and evaluate the efficacy and safety data of Dengvaxia for the treatment of severe secondary dengue infection. Dengvaxia is the brand name for chimeric yellow fever-dengue-tetravalent dengue vaccine (CYD-TDV). A literature search through PubMed was conducted using the keywords ‘dengue vaccine’, ‘Dengvaxia’, ‘efficacy’ or ‘safety’. Trials were selected if they appropriately assessed vaccine efficacy or were related to the vaccine approval process for CYD-TDV. Findings from this review underline the evolution of vaccine efficacy against seroprevalence, serotypes, and various ages. There are currently no preventive measures or antiviral treatments for dengue; CYD-TDV is the first vaccine to receive US Food and Drug Administration approval. Protective responses seen with the complete administration of CYD-TDV can become a standardized tool as part of a world vaccination program.


2021 ◽  
Author(s):  
Jinqiu Yuan ◽  
Bolin Cao ◽  
Changhua Zhang ◽  
Meiqi Xin ◽  
Yuan Fang ◽  
...  

BACKGROUND Factory workers who resumed work during the pandemic is a sub-population of higher risk of COVID-19 infection than that of the general population. Maintaining good compliance with personal preventive measures during the pandemic plays an important role in achieving the balance between COVID-19 control and work resumption. OBJECTIVE This observational prospective cohort study investigated the changes in compliance to personal preventive measures (i.e., facemask wearing, hand hygiene, household disinfection, avoiding social/meal gathering and avoiding crowed places), depressive symptoms and sleep quality among factory workers who resumed work within a 3-month follow-up period. METHODS Inclusion criteria for this cohort study were the following: 1) full-time employees aged ≥18 years who had resumed work, and 2) willing to leave contacts (mobile or social media account) to complete the follow-up survey. A stratified two-stage cluster sampling design was used. We randomly selected 12 factories in Shenzhen. And all eligible employees in these factories were invite to complete two web-based surveys three months apart. A total of 1311 Chinese adult factory workers completed the baseline survey in March 2020, and 663 (50.6%) completed the follow-up survey three months later. RESULTS Significant decline was observed in consistent facemask wearing in workplace (from 98.0% at baseline to 90.3% at Month 3, P<.001) and in other public spaces (from 97.1% at baseline to 94.4% at Month 3, P=.02), sanitizing hands (from 70.9% at baseline to 48.0% at Month 3, P<.001), household disinfection (from 47.7% at baseline to 37.9% at Month 3, P<.001) and moderate-to-severe depression (from 6.0% at baseline to 0.6% at Month 3, P<.001) over the follow-up period. Significant improvement in avoiding crowed places (from 69.8% at baseline to 77.4% at Month 3, P=.002) and sleep quality (proportion of participants reporting poor sleeping quality dropped from 3.9% at baseline to 1.2% at Month 3, P=.002) was also observed. CONCLUSIONS There were significant decline in some personal preventive measures and significant improvement in mental health status among a cohort of Chinese factory workers who resumed work during COVID-19. Health promotion are needed to maintain good compliance to personal preventive measures. Psychological support for workers during work resumption is necessary.


Author(s):  
Joseph Nelson Siewe Fodjo ◽  
Leonard Ngarka ◽  
Wepnyu Y. Njamnshi ◽  
Leonard N. Nfor ◽  
Michel K. Mengnjo ◽  
...  

Since March 2020, the Cameroonian government implemented nationwide measures to stall COVID-19 transmission. However, little is known about how well these unprecedented measures are being observed as the pandemic evolves. We conducted a six-month online survey to assess the preventive behaviour of Cameroonian adults during the COVID-19 outbreak. A five-point adherence score was constructed based on self-reported observance of the following preventive measures: physical distancing, face mask use, hand hygiene, not touching one’s face, and covering the mouth when coughing or sneezing. Predictors of adherence were investigated using ordinal logistic regression models. Of the 7381 responses received from all ten regions, 73.3% were from male respondents and overall mean age was 32.8 ± 10.8 years. Overall mean adherence score was 3.96 ± 1.11 on a scale of 0–5. Mean weekly adherence scores were initially high, but gradually decreased over time accompanied by increasing incidence of COVID-19 during the last study weeks. Predictors for higher adherence included higher age, receiving COVID-19 information from health personnel, and agreeing with the necessity of lockdown measures. Meanwhile, experiencing flu-like symptoms was associated with poor adherence. Continuous observance of preventive measures should be encouraged among Cameroonians in the medium- to long-term to avoid a resurgence in COVID-19 infections.


Vaccines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 765
Author(s):  
Amel Ahmed Fayed ◽  
Abeer Salem Al Shahrani ◽  
Leenah Tawfiq Almanea ◽  
Nardeen Ibrahim Alsweed ◽  
Layla Mohammed Almarzoug ◽  
...  

This study aimed to assess the willingness to receive the coronavirus disease 2019 (COVID-19) and seasonal influenza vaccines and vaccine uptake during the early stage of the national vaccination campaign in Saudi Arabia. A cross-sectional online survey was conducted among adult Saudis between 20 January and 20 March 2021. The questionnaire addressed vaccine hesitancy, perceived risk, willingness, and vaccine uptake. Approximately 39% of the participants expressed vaccine hesitancy, and 29.8% and 24% felt highly vulnerable to contracting COVID-19 and seasonal influenza, respectively. The majority (59.5%) were willing to receive the COVID-19 vaccine, although only 31.7% were willing to receive the flu vaccine. Adjusted analysis showed that vaccine hesitancy (OR 0.34, 95% CI 0.27–0.43) and the perception of being at high risk (OR 2.78, 95% CI 1.68–4.60) independently affected the intention to be vaccinated. Vaccine hesitancy was similar among those who were willing to be vaccinated (29.8%) and those who had already been vaccinated (33.1%). The perceived risk was significantly higher among those who had been vaccinated (48.1%) than among those who were willing to be vaccinated but had not yet been vaccinated (29.1%). In conclusion, the acceptance of the COVID-19 vaccine in Saudi Arabia is high. Saudis who received the vaccine had a similar level of vaccine hesitancy and a higher level of perceived risk.


2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Junko Okumura

Abstract Background Although the scale of the coronavirus disease (COVID-19) pandemic was relatively small in Japan compared with the rest of the world, the polarisation of areas into high- and low-COVID-19-incidence areas was observed among the 47 prefectures. The aims of this study were not only identifying the factors associated with the polarised COVID-19 pandemic in Japan but also discussing effective preventive measures. Methods This was an ecological study using online survey data which was cross-sectionally conducted by the author. A total of 6000 respondents who resided in 10 low- and 10 high-COVID-19 incidence prefectures, with a wide gap in terms of COVID-19 incidence, in Japan were recruited. Data on COVID-19 cases and geodemographic information were obtained from official government sites. Statistical analyses were conducted to compare variables between the two areas and age groups. Results This study revealed that that age influenced people’s behaviours and perceptions, except one behaviour of ‘wearing facemasks’. The major factors significantly associated with the cumulative number of COVID-19 cases per 100,000 people were ‘commuting by private automobile’ (adjusted odds ratio [AOR], 0.444; 95% confidence interval [CI], 0.394–0.501), ‘commuting by public transportation’ (AOR, 6.813; 95% CI, 5.567–8.336), ‘washing hands’ (AOR, 1.233; 95% CI, 1.005–1.511), ‘opening windows regularly’ (AOR, 1.248; 95% CI, 1.104–1.412), ‘avoiding crowded places (AOR, 0.757; 95% CI, 0.641–0.893), ‘non-scheduled visits to drinking places’ (AOR, 1.212; 95% CI, 1.054–1.392) and ‘perceived risk of contracting COVID-19’ (AOR, 1.380; 95% CI, 1.180–1.612). These factors were strongly associated with age groups. Conclusions Effective preventive measures for COVID-19 transmission can be developed by understanding the characteristics of populated areas, such as public transportation infrastructure and younger people’s movements and behaviours in relation to the population age structure to contain the current epidemic and protect the most vulnerable elderly people.


Author(s):  
Tuyen Dinh Hoang ◽  
Robert Colebunders ◽  
Joseph Nelson Siewe Fodjo ◽  
Nhan Phuc Thanh Nguyen ◽  
Trung Dinh Tran ◽  
...  

The COVID-19 pandemic and associated restrictive measures implemented may considerably affect people’s lives. This study aimed to assess the well-being of Vietnamese people after COVID-19 lockdown measures were lifted and life gradually returned to normal. An online survey was organized from 21 to 25 April 2020 among Vietnamese residents aged 18 and over. The survey was launched by the Hue University of Medicine and Pharmacy. The WHO-5 Well-Being Index (scored 0–25) was used to score participants’ well-being. A multivariate logistic regression model was used to determine the predictors of well-being. A total of 1922 responses were analyzed (mean age: 31 years; 30.5% male; 88.2% health professionals or students in the health sector). The mean well-being score was 17.35 ± 4.97. Determinants of a high well-being score (≥13) included older age, eating healthy food, practicing physical exercise, working from home, and adhering to the COVID-19 preventive measures. Female participants, persons worried about their relatives’ health, and smokers were more likely to have a low well-being score. In conclusion, after the lockdown measures were lifted, the Vietnamese have people continued to follow COVID-19 preventive measures, and most of them scored high on the well-being scale. Waiting to achieve large-scale COVID-19 vaccine coverage, promoting preventive COVID-19 measures remains important, together with strategies to guarantee the well-being of the Vietnamese people.


Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 738
Author(s):  
Cristina Gentile ◽  
Francesco Chiarelli

Rickets refers to a deficient mineralization of the growth plate cartilage, predominantly affecting longer bones. Despite the fact that preventive measures are available, it is still a common disease worldwide; nutritional rickets, due to vitamin D deficiency or dietary calcium inadequate intake, remains the most common form. Medical history, physical examination, radiologic features and biochemical tests are essential for diagnosis. Although recent studies suggest hypophosphatemia as the leading alteration, rickets is classically divided into two categories: calcipenic rickets and phosphopenic rickets. Knowledge of this categorization and of respective clinical and laboratory features is essential for rapid diagnosis and correct management. The aim of this review is to analyze the epidemiological, pathogenetic, clinical, and therapeutic aspects of the different forms of rickets, describing the novelties on this “long-lived” disease.


Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 500
Author(s):  
Marco Trabucco Aurilio ◽  
Francesco Saverio Mennini ◽  
Simone Gazzillo ◽  
Laura Massini ◽  
Matteo Bolcato ◽  
...  

Background: While the COVID-19 pandemic has spread globally, health systems are overwhelmed by both direct and indirect mortality from other treatable conditions. COVID-19 vaccination was crucial to preventing and eliminating the disease, so vaccine development for COVID-19 was fast-tracked worldwide. Despite the fact that vaccination is commonly recognized as the most effective approach, according to the World Health Organization (WHO), vaccine hesitancy is a global health issue. Methods: We conducted a cross-sectional online survey of nurses in four different regions in Italy between 20 and 28 December 2020 to obtain data on the acceptance of the upcoming COVID-19 vaccination in order to plan specific interventions to increase the rate of vaccine coverage. Results: A total of 531 out of the 5000 nurses invited completed the online questionnaire. Most of the nurses enrolled in the study (73.4%) were female. Among the nurses, 91.5% intended to accept vaccination, whereas 2.3% were opposed and 6.2% were undecided. Female sex and confidence in vaccine efficacy represent the main predictors of vaccine intention among the study population using a logistic regression model, while other factors including vaccine safety concerns (side effects) were non-significant. Conclusions: Despite the availability of a safe and effective vaccine, intention to be vaccinated was suboptimal among nurses in our sample. We also found a significant number of people undecided as to whether to accept the vaccine. Contrary to expectations, concerns about the safety of the vaccine were not found to affect the acceptance rate; nurses’ perception of vaccine efficacy and female sex were the main influencing factors on attitudes toward vaccination in our sample. Since the success of the COVID-19 immunization plan depends on the uptake rate, these findings are of great interest for public health policies. Interventions aimed at increasing employee awareness of vaccination efficacy should be promoted among nurses in order to increase the number of vaccinated people.


2020 ◽  
pp. bmjsrh-2020-200687
Author(s):  
Tom Nadarzynski ◽  
Ynez Symonds ◽  
Robert Carroll ◽  
Jo Gibbs ◽  
Sally Kidsley ◽  
...  

ObjectivesThe digitalisation of sexual and reproductive health (SRH) services offers valuable opportunities to deliver contraceptive pills and chlamydia treatment by post. We aimed to examine the acceptability of remote prescribing and ‘medication-by-post’ in SRH.Study designAn online survey assessing attitudes towards remote management was distributed in three UK SRH clinics and via an integrated sexually transmitted infection (STI) postal self-sampling service. Logistic regressions were performed to identify potential correlates.ResultsThere were 1281 participants (74% female and 49% <25 years old). Some 8% of participants reported having received medication via post and 83% were willing to receive chlamydia treatment and contraceptive pills by post. Lower acceptability was observed among participants who were: >45 years old (OR 0.43 (95% CI 0.23–0.81)), screened for STIs less than once annually (OR 0.63 (0.42–0.93)), concerned about confidentiality (OR 0.21 (0.90–0.50)), concerned about absence during delivery (OR 0.09 (0.02–0.32)) or unwilling to provide blood pressure readings (OR 0.22 (0.04–0.97)). Higher acceptability was observed among participants who reported: previously receiving medication by post (OR 4.63 (1.44–14.8)), preference for home delivery over clinic collection (OR 24.1 (11.1–51.9)), preference for home STI testing (OR 10.3 (6.16–17.4)), ability to communicate with health advisors (OR 4.01 (1.03–15.6)) and willingness to: register their real name (OR 3.09 (1.43–10.6)), complete online health questionnaires (OR 3.09 (1.43–10.6)) and use generic contraceptive pills (OR 2.88 (1.21–6.83)).ConclusionsPostal treatment and entering information online to allow remote prescribing were acceptable methods for SRH services and should be considered alongside medication collection in pharmacies. These methods could be particularly useful for patients facing barriers in accessing SRH. The cost-effectiveness and implementation of these novel methods of service delivery should be further investigated.


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