scholarly journals m-Health strategies for HIV Post-Exposure Prophylaxis: Patent Prospection, Systematic Literature Review and Analysis of Mobile Applications (Preprint)

2020 ◽  
Author(s):  
Artur Acelino Francisco Luz Nunes Queiroz ◽  
Isabel Amélia Costa Mendes ◽  
Simone De Godoy ◽  
Luís Lapão ◽  
Sônia Dias

UNSTRUCTURED Our aim was to identify and analyze applications for smart phones that address post-exposure prophylaxis to HIV. We conducted a descriptive-exploratory study, in threesequential phases: systematic literature review, patents analysis and applicationexploration. The review of the literature in the databases PubMed, Web of Knowledge,Scopus, Cochrane, Embase, Science Direct, Eric, Treasure and CINAHL. The secondphase corresponded to an exploration of applications in the INPI, OIMP andESPACENET patent databases. In the third phase, we performed an analysis on thetwo major application libraries: Google Play Store and App Stores. At each stage, theselected studies/patents/apps were analyzed and pre-selected, according to theinclusion and exclusion criteria, by reading their titles and descriptions. Theapplications were evaluated by name, characteristics, functions and availability for themain systems (iOS or Android). As for the patent registrations, these were analyzeddescriptively according to the information retrieved from the patent bases, titles,descriptions and applicants/inventors. None of the studies reported the creation orvalidation of an application, this represent a gap between the number of applicationavailable and the scientific research on the field.

2020 ◽  
Vol 19 (3) ◽  
pp. 242-248
Author(s):  
Anthony Idowu Ajayi ◽  
Mohammed Sanusi Yusuf ◽  
Elmon Mudefi ◽  
Oladele Vincent Adeniyi ◽  
Ntombana Rala ◽  
...  

2016 ◽  
Vol 12 (3) ◽  
Author(s):  
Shalini Sivananjiah Pradeep ◽  
Suman Gadicherla Raghu ◽  
Prathab A G ◽  
Banashankari G Rudresh ◽  
Radhika Kunnavil

The working environment of healthcare workers (HCW) exposes them to sharp injuries. This communication attempts to examine the injury registers, incidence of sharps injuries and blood splash exposures, and the post-exposure prophylaxis status of employees in a tertiary care hospital. Analysis included records form 54 locations of two units of a tertiary hospital attached to a Medical College. Maintenance of the injury register overall was highly satisfactory in both units. Two hundred and nine injuries were recorded from both units of the hospital. The majority of injuries (60.5%) occurred in the age group of 20-30 years with 70% among females. Waste handlers were at increased risk during waste management procedures. Thirty two percent of sharps injury injuries occurred in wards. Of the ward nursing staff, 25.3% received sharps injuries. Post-exposure prophylaxis for Hepatitis B (primary dose) was given to 25 HCWs; 11 received booster doses. The basic regimen for HIV post-exposure prophylaxis was given to 4 HCWs. Awareness about records maintenance, regular documentation, awareness and training, and implementation of appropriate preventive measures can reduce the incidence of injuries. Key words: Sharps, injury register, Health care workers (HCW),Post exposure prophylaxis (PEP)


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S521-S522
Author(s):  
Jennifer R Silva-Nash ◽  
Stacie Bordelon ◽  
Ryan K Dare ◽  
Sherrie Searcy

Abstract Background Nonoccupational post exposure prophylaxis (nPEP) following sexual assault can prevent HIV transmission. A standardized Emergency Department (ED) protocol for evaluation, treatment, and follow up for post assault victims was implemented to improve compliance with CDC nPEP guidelines. Methods A single-center observational study of post sexual assault patients before/after implementation of an ED nPEP protocol was conducted by comparing the appropriateness of prescriptions, labs, and necessary follow up. A standardized order-set based on CDC nPEP guidelines, with involvement of an HIV pharmacist and ID clinic, was implemented during the 2018-2019 academic year. Clinical data from pre-intervention period (07/2016-06/2017) was compared to post-intervention period (07/2018-08/2019) following a 1-year washout period. Results During the study, 147 post-sexual assault patients (59 Pre, 88 Post) were included. One hundred thirty-three (90.4%) were female, 68 (46.6%) were African American and 133 (90.4%) were candidates for nPEP. Median time to presentation following assault was 12.6 hours. nPEP was offered to 40 (67.8%) and 84 (95.5%) patients (P< 0.001) and ultimately prescribed to 29 (49.2%) and 71 (80.7%) patients (P< 0.001) in pre and post periods respectively. Renal function (37.3% vs 88.6%; P< 0.001), pregnancy (39.0% vs 79.6%; P< 0.001), syphilis (3.4% vs 89.8%; P< 0.001), hepatitis B (15.3% vs 95.5%; P< 0.001) and hepatitis C (27.1% vs 94.3%) screening occurred more frequently during the post period. Labratory, nPEP Prescription and Follow up Details for Patients Prescribed nPEP Conclusion The standardization of an nPEP ED protocol for sexual assault victims resulted in increased nPEP administration, appropriateness of prescription, screening for other sexually transmitted infectious and scheduling follow up care. While guideline compliance dramatically improved, further interventions are likely warranted in this vulnerable population. Disclosures Ryan K. Dare, MD, MS, Accelerate Diagnostics, Inc (Research Grant or Support)


2021 ◽  
pp. 1-10
Author(s):  
P Meyerhoff ◽  
S Manekeller ◽  
N Saleh ◽  
C Boesecke ◽  
S Schlabe ◽  
...  

Buildings ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 244
Author(s):  
Ana Maria Bueno ◽  
Antonio Augusto de Paula Xavier ◽  
Evandro Eduardo Broday

The thermal environment is one of the main factors that influence thermal comfort and, consequently, the productivity of occupants inside buildings. Throughout the years, research has described the connection between thermal comfort and productivity. Mathematical models have been established in the attempt to predict changes in productivity according to thermal variations in the environment. Some of these models have failed for a number of reasons, including the understanding of the effect that several environment variables have had on performance. From this context, a systematic literature review was carried out with the aim of verifying the connection between thermal comfort and productivity and the combinations of different thermal and personal factors that can have an effect on productivity. A hundred and twenty-eight articles were found which show a connection between productivity and some thermal comfort variables. By means of specific inclusion and exclusion criteria, 60 articles were selected for a final analysis. The main conclusions found in this study were: (i) the vast majority of research uses subjective measures and/or a combination of methods to evaluate productivity; (ii) performance/productivity can be attained within an ampler temperature range; (iii) few studies present ways of calculating productivity.


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