scholarly journals Usefulness of Smartphone Applications for Improving Nutritional Status of Pancreatic Cancer Patients: A Randomized Controlled Trial (Preprint)

2020 ◽  
Author(s):  
Jiyoung Keum ◽  
Moon Jae Chung ◽  
Youngin Kim ◽  
Hyunyoung Ko ◽  
Min Je Sung ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Nutritional Support ◽  
Mobile App ◽  
Ductal Adenocarcinoma ◽  
User Group ◽  
European Organization ◽  
Skeletal Muscle Index ◽  
Quality Of Life Scale

BACKGROUND Approximately 80% of pancreatic ductal adenocarcinoma (PDAC) patients suffer from anorexia, weight loss, asthenia, and a poor prognosis. Moreover, in this context, nutritional management of PDAC patients during the chemotherapy is a key factor in prognosis than any other cancer. PDAC is the type cancer that requires the most nutritional support. Mobile applications (apps) have the potential to provide easily accessible nutritional support for patients with PDAC. OBJECTIVE We aimed to evaluate the efficacy of a mobile app-based program, Noom, in patients receiving chemotherapy for PDAC METHODS We prospectively enrolled patients who were newly diagnosed with unresectable PDAC and randomly assigned them into the Noom user group (n=20) and the non-Noom user group (n=20). The in-app interventions with behavior and nutritional education lasted for 12 weeks. Dietitians monitored these data and provided nutritional feedback. Patients also completed paper questionnaires at baseline and after 4, 8, and 12 weeks. RESULTS Above average Noom users showed a significant improvement in nutritional status according to the Patient-Generated Subjective Global Assessment (P=.03). Noom users showed a statistically significant improvement on the Global Health Status and Quality of Life scale compared to non-Noom users based on the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire (P=.02). Particularly, skeletal muscle index was significantly higher in above average Noom users compared to non-Noom users during the study period (+5.58% versus -13.96%, P=.04). CONCLUSIONS This pilot study demonstrated that a mobile app-based approach was beneficial for nutritional and psychological support for patients receiving chemotherapy for PDAC. CLINICALTRIAL ClinicalTrials.gov NCT04109495

352 QUALITY OF LIFE OF PATIENTS UNDERGOING SURGERY FOR ESOPHAGEAL AND GASTROESOPHAGEAL JUNCTION CANCER

2020 ◽  
Vol 33 (Supplement_1) ◽  
Author(s):  
I Lidoriki ◽  
D Schizas ◽  
K Mylonas ◽  
A Alexandrou ◽  
I Karavokyros ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Physical Functioning ◽  
Nutritional Assessment ◽  
Preoperative Evaluation ◽  
Gastroesophageal Junction ◽  
Skeletal Muscle Index ◽  
Gastroesophageal Junction Cancer ◽  
Eortc Qlq

Abstract   The assessment of patients’ quality of life is increasingly gaining ground as an effective approach to evaluate treatment efficacy and patients satisfaction in the clinical setting. The aim of this study was to investigate the association between patients’ preoperative nutritional status and quality of life, as well as to examine quality of life changes at six months postoperatively in patients undergoing surgery for esophageal and gastroesophageal junction cancer. Methods The study sample consisted of 93 patients with esophageal (n = 14) and gastroesophageal junction cancer (n = 79) who were admitted for surgery in the xxxxx between September 2015 and July 2019. Out of them, 77 patients underwent esophagectomy while 16 patients underwent total gastrectomy. The preoperative evaluation of patients’ nutritional status was based on Patient Generated Subjective Global Assessment (PG-SGA) and Skeletal Muscle Index (SMI) derived from analysis of CT scans, while the assessment of patients’ quality of life (QoL) was based on EORTC QLQ-C30 questionnaire (version 3.0). Patients’ follow-up was done six months postoperatively. Results Forty three patients (46.2%) were diagnosed with sarcopenia. The prevalence of malnutrition was 64%. Sarcopenic patients scored lower on Global Health (59.94 ± 19.21 vs 65.68 ± 20.08, p = 0.050), Physical Functioning (77.63 ± 23.08 vs 86.58 ± 15.26, p = 0.003) and higher on Fatigue (35.80 ± 25.19 vs 25.73 ± 22.31, p = 0.008) compared with non-sarcopenic patients. Μalnourished patients exhibited more impaired QoL, except Emotional Functioning, compared to well-nourished patients. Physical Functioning (79.9 ± 18.3 vs 88.2 ± 12.9, p = 0.004) and Social Functioning (67.7 ± 22.6 vs 83.1 ± 20.8, p < 0.001) were lower, while Pain (19.9 ± 19.0 vs 13.9 ± 17.9, p = 0.050), Diarrhea (19.4 ± 22.2 vs 9.7 ± 19.5, p = 0,011) and Financial Difficulties (21.0 ± 21.1 vs 12.9 ± 23.7, p = 0.031) were higher at six months postoperatively compared to the preoperative levels. Conclusion Sarcopenia and malnutrition affected several parameters of health related QoL in patients undergoing surgery for esophageal and gastroesophageal junction cancer. Moreover, various components of the QoL significantly declined at six months postoperatively. These results indicate that preoperative nutritional assessment is necessary in order to prevent further deterioration of nutritional and functional status, which, in turn may worsen patients’ QoL.

scholarly journals Effect of Chocolate on Older Cancer Patients in Palliative Care: A Randomised Controlled Study

2021 ◽  
Author(s):  
Josiane C. Vettori ◽  
Luanda G. da-Silva ◽  
Karina Pfrimer ◽  
Jordão-Junior Alceu A ◽  
Paulo Louzada-Junior ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oxidative Stress ◽  
Palliative Care ◽  
Body Composition ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Controlled Study ◽  
European Organization ◽  
Older Cancer Patients

Abstract Background Older advanced stage cancer patients, with changes in metabolic and nutritional status, represent an important demand for palliative care. The objective of the present study was to determine the effects of 4 weeks of chocolate consumption on the nutritional status, quality of life, body composition, oxidative stress and inflammaory activity of older cancer patients in palliative care. Methods Older cancer patients in palliative care with ambulatory monitoring were randomized to the following groups: control (CG, n = 15), intervention with 55% cocoa chocolate (IG1, n = 16) and intervention with white chocolate (IG2, n = 15) groups and evaluated before and after 4 weeks of treatment for nutritional status, food consumption, anthropometry, body composition, and laboratory parameters, and quality of life using the instrument of the European Organization for the Research and Treatment of Cancer. Results IG1 progressed with increased screening (p < 0.01) and nutritional (p = 0.04) scores on the Mini Nutritional Assessment tool. Anthropometry and body composition did not change. Regarding antioxidant capacity, reduced glutathione levels increased in IG2 (p = 0.04) and were higher than in IG1 (p < 0.01). Malondealdehyde levels were reduced in IG2 (p = 0.02) at the end of the study. Regarding quality of life, functionality improved in IG1, with a higher score in the functional domain (p = 0.03), and in the role functioning (p < 0.01) and in the social (p < 0.01) subdomains. Conclusions The consumption of chocolate with a greater cocoa content may contribute to the improvement of nutritional status and functionality among older cancer patients in palliative care. The consumption of white chocolate was associated with improved oxidative stress. Trial registration: ClinicalTrials.gov NCT04367493 - April 29, 2020. Retrospectively registered.

Nutritional status and quality of life in patients with gastric cancer in China.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15508-e15508
Author(s):  
Hongli Li ◽  
Shaohua Ge ◽  
Yi Ba
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Assessment Tool ◽  
Subjective Global Assessment ◽  
Preliminary Assessment ◽  
European Organization ◽  
Gastric Cancer Patients

e15508 Background: The incidence of gastric cancer is much higher in China than in any other country. Although the overall survival rate of patients with gastric cancer has increased due to the advancements in multimodality management. However, significant morbidity, including loss of appetite, dysphagia, nausea, and vomiting is still associated with gastric cancer patients. These symptoms have a profound impact on nutritional status and quality of life in these patients. The primary objective of the present study was to assess the nutritional status and quality of life in gastric cancer patients. Methods: A preliminary assessment of patients’ nutritional status, quality of life, and medical characteristics was conducted using the Patient Generated Subjective Global Assessment (PG-SGA) and the European Organization for Research and Treatment of Cancer quality of life (QOL-C30, version 3) questionnaires. The PG-SGA is a clinical nutrition assessment tool used to evaluate oncology patients. The nutritional status of the patients fell into three groups by a score of PG-SGA-A, -B, and C. Results: A preliminary assessment of patients’ nutritional status, quality of life, and medical characteristics was conducted using the Patient Generated Subjective Global Assessment (PG-SGA) and the European Organization for Research and Treatment of Cancer quality of life (QOL-C30, version 3) questionnaires. The PG-SGA is a clinical nutrition assessment tool used to evaluate oncology patients. The nutritional status of the patients fell into three groups by a score of PG-SGA-A, -B, and C. Conclusions: These results suggest that the nutritional status of the patients with stomach cancer may impact on their QoL. It is necessary to develop nutritional intervention to improve QoL in gastric cancer patients.

scholarly journals Association of malnutrition and low quality of life among cancer patients receiving chemotherapy, Palestine

2021 ◽  
Vol 27 (5) ◽  
pp. 459-466
Author(s):  
Manal Badrasawi ◽  
Aseel Al-Adhame ◽  
Aseel Doufish
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Final Analysis ◽  
Cross Sectional Study ◽  
Poor Quality ◽  
Cross Sectional ◽  
European Organization ◽  
The Relationship

Background: Malnutrition is significantly associated with poor clinical outcomes and reduced quality of life among cancer patients. Although the number of cancer patients receiving chemotherapy has increased in Palestine, there has been limited research on the relationship between malnutrition and quality of life. Aims: To determine the relationship between nutritional status and quality of life of cancer patients receiving chemotherapy at Al-Hussein Governmental Hospital in Biet-Jala, Palestine. Methods: This cross-sectional study included all the patients receiving chemotherapy between 2018 and 2019. Nutritional status was assessed using anthropometric measurements and biochemical data retrieved from the participating patients’ files. The clinical assessment of malnutrition was done using the Subjective Global Assessment, and quality of life was assessed using the European Organization for Research and Treatment of Cancer QLQ-C30 questionnaire version 3. Results: One hundred patients (79 female, 21 male) were included in the final analysis. The results revealed that 25% of the patients were severely malnourished, and 42% were mildly to moderately malnourished. There was a significant relationship between malnutrition and quality of life in the following domains: physical functioning, cognitive functioning and fatigue. Conclusions: Malnutrition is prevalent among Palestinian cancer patients receiving chemotherapy, and it is associated with poor quality of life. The results of the study highlight the need for nutritional support programmes for cancer patients to enhance their nutritional status and improve their quality of life.

scholarly journals The effect of additional nutritional support as part of the rehabilitation program on the quality of life and morbidity in children with recurrent respiratory pathology

2018 ◽  
pp. 238-244 ◽  
Author(s):  
R. Z. Akhmetshin ◽  
N. A. Druzhinina ◽  
L. M. Nasibullina ◽  
G. P. Shiryaeva ◽  
Ch. R. Bakieva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Status ◽  
Nutritional Support ◽  
Respiratory Infections ◽  
Rehabilitation Program ◽  
Health Improvement ◽  
Improvement Program ◽  
Comprehensive Health ◽  
Respiratory Pathology

Objective of the study: Assess the health and quality of life in children with recurrent respiratory pathology and justify the effectiveness of comprehensive rehabilitation program to improve health involving additional nutritional support.Materials and methods: 101 children aged 5–9 years with recurrent respiratory pathology received a non-comparative clinical examination and rehabilitation. The first group included 75 children with disorders of nutritional status that were identified upon results of physical examination, anthropometric measurements, including body composition analysis (bioimpedance measurement), biochemical parameters and actual nutrition evaluation. The observed children of the main group received «PediaSure with fiber» functional product as part of the complex rehabilitation therapy to replenish the diet with the basic nutrients, vitamins and trace elements. The second group of 26 children comparable in age and gender, but not having disorders of nutritional status was allocated in order to assess the impact of the nutritional deficiency on the severity of recurrent respiratory disease. Those children received only general health therapy and usual sanatorium traditional food. The effectiveness of the therapy was assessed on the basis of the positive dynamics of the nutritional status and the quality of life study using the questionnaire Pediatric Quality of Life Questionnaire (Generic Core Scales). The study was conducted in Duslyk children’s sanatorium in Ufa.Results: The comprehensive health improvement program and additional nutritional support in children with recurrent respiratory pathology showed a significant improvement in anthropometric data, a 2.5-fold decrease in the average number (from 7.12 to 2.9, p <0.05), and 1.8 -fold decrease in the average duration (from 11.88 to 6.76 days, p <0.05) of episodes of recurrent respiratory infections, and also allowed to achieve significant improvement in all parameters of the children’s quality of life.Conclusion: The comprehensive health improvement program and additional nutritional support in children with recurrent respiratory pathology contribute to improving the quality of life, increasing adaptive capacity, reducing the frequency and duration of acute respiratory infections.

Stroke Specific Quality of Life Scale--French Version

2018 ◽  
Author(s):  
Nicolas Legris ◽  
Hervé Devilliers ◽  
Anaïs Daumas ◽  
Didier Carnet ◽  
Jean-Pierre Charpy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
French Version ◽  
Quality Of Life Scale ◽  
Life Scale

Acne Quality of Life Scale

1998 ◽  
Author(s):  
Madhulika A. Gupta ◽  
Andrew M. Johnson ◽  
Aditya K. Gupta
Keyword(s):  
Quality Of Life ◽  
Quality Of Life Scale ◽  
Life Scale
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