Incidental Extra-Colonic Findings in CT Colonography at Riyadh Region (Preprint)

2020 ◽  
Author(s):  
Muhannad Alanazi

BACKGROUND Computed tomography colonography (CTC) is a new radiologic technique for examination of the colorectum. The search for, analysis and interpretation of extracolonic findings (ECFs) are a matter of permanent debate and review, given the arguments for and against them. OBJECTIVE To assess the prevalence and type of extracolonic findings (ECFs) in a screening population undergoing computed tomography colonography (CTC) in Riyadh region. METHODS This retrospective study was conducted in Riyadh region. To achieve the objectives of this study 305 subjects medical records were reviewed, where male represented 55% of participants and female represented only 45%. RESULTS About 21% of subjects had any type Extra Colonic Findings (ECFs) where about 74 incidental findings were identified in 65 patients. Out of these findings; 6 patients (9%) required immediate medical attention or urgent imaging/intervention, these included high suspicious of extracolonic malignancy or active infection, 16 patients (25%) required either further imaging and characterization, or follow up imaging, these included undetermined masses or nodules, while 43 patients (66%) required either reassurance or life style modification, which included extensive atherosclerotic changes, fatty liver or spondylolisthesis. CONCLUSIONS Colon cancer is one of the leading cause of mortality and morbidity in our Saudi Arabia community. Early detection of colon cancer and its precursor (i.e. polyps) is essential for successful management.

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Domenic Di Rollo ◽  
Donald McMillan ◽  
Paul Horgan ◽  
David Mansouri

Abstract Aim CT virtual colonoscopy (CTC) is increasingly relied upon in bowel screening programmes. Concern remains regarding the prevalence of incidental extra-colonic findings (ECF). The present study reports on the prevalence and implications of ECF as part of a UK bowel screening programme. Methods Reports for 400 consecutive CTCs carried out as part of the Scottish Bowel Screening Programme were examined. Intra and extracolonic findings were recorded using the CT Colonography Reporting and Data System (C-RADS). Medical records pertaining to ECF follow-up were examined. Cost analysis was performed. Results 394 patients were included. 146 (37%) were males. Median age was 65 years, median follow-up was 72 months (Range 32-110). 92 (23%) patients had CTC as their primary investigation, 302 (77%) patients underwent CTC due to failed colonoscopy. Overall, 244/394 (62%) patients had ECF with only 45/394 (11%) found to have colonic pathology. 65/394 (16%) had moderately or highly significant ECF, (C-RADS E3-4). Of the 244 patients with ECF, 59 (24%) underwent further investigation, estimated cost £17,589. The majority, 37/59 (63%) were found to have benign disease after follow-up. Conclusion ECF at CTC are more frequent than colonic findings. The majority of ECF investigated are found to be benign yet a quarter of ECF are further investigated at a cost to the health service and the patient. Clinicians should be judicial when ordering and consenting patients with regards ECF and its implications if CTC is considered. Particularly when the test is part of a public funded and voluntary screening programme.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kil-yong Lee ◽  
Jaeim Lee ◽  
Youn Young Park ◽  
Seong Taek Oh

Abstract Background Routine colonoscopy is recommended to determine the coexistence of colon cancer after medical treatment for colon diverticulitis. However, in the case of uncomplicated diverticulitis diagnosed by computed tomography, the clinical relevance of routine follow-up colonoscopy has recently been debated. Yet, the role of follow-up colonoscopy for right colon diverticulitis, which tends to develop at a younger age than left colon diverticulitis, has not been specifically evaluated. Therefore, we aimed to evaluate the incidence of right colon cancer or colonic adenomatous polyps, detected by routine colonoscopy, after conservative management of acute uncomplicated right colon diverticulitis. Methods Patients with uncomplicated right colon diverticulitis (modified Hinchey stage Ia) diagnosed by computed tomography imaging, between 2011 and 2017, and who underwent follow-up colonoscopy surveillance after treatment were included. The primary outcome was the incidence of colon cancer, with the detection rate of adenoma being the secondary outcome. Information for analysis was retrieved retrospectively from patients’ medical records. Results The study group included 330 consecutive patients, with a mean age of 41.9 years, and 51.9% being men. For the primary outcome, the rate of colon cancer on follow-up colonoscopy was 0.3% (1/330 cases). The rate of adenoma detection was 20.9% (69/330 cases) and advanced adenoma (> 10 mm in diameter; or exhibiting a > 25% villous component or severe dysplasia), including colon cancer, was observed in 9 patients (2.7%). Conclusions In patients with acute uncomplicated right colonic diverticulitis, routine colonoscopy after conservative treatment may be necessary because although the colon cancer detection rate is low, it is possible to detect advanced colon adenoma.


2013 ◽  
Vol 49 (2) ◽  
pp. 191-201 ◽  
Author(s):  
Bodil Elisabeth Engelmann ◽  
Annika Loft ◽  
Andreas Kjær ◽  
Hans Jørgen Nielsen ◽  
Anne Kiil Berthelsen ◽  
...  

2015 ◽  
Vol 48 (4) ◽  
pp. 211-215 ◽  
Author(s):  
Marcelo Petrilli ◽  
Andreza Almeida Senerchia ◽  
Antonio Sergio Petrilli ◽  
Henrique Manoel Lederman ◽  
Reynaldo Jesus Garcia Filho

Abstract Objective: To report the results of computed tomography (CT)-guided percutaneous resection of the nidus in 18 cases of osteoid osteoma. Materials and Methods: The medical records of 18 cases of osteoid osteoma in children, adolescents and young adults, who underwent CT-guided removal of the nidus between November, 2004 and March, 2009 were reviewed retrospectively for demographic data, lesion site, clinical outcome and complications after procedure. Results: Clinical follow-up was available for all cases at a median of 29 months (range 6–60 months). No persistence of pre-procedural pain was noted on 17 patients. Only one patient experienced recurrence of symptoms 12 months after percutaneous resection, and was successfully retreated by the same technique, resulting in a secondary success rate of 18/18 (100%). Conclusion: CT-guided removal or destruction of the nidus is a safe and effective alternative to surgical resection of the osteoid osteoma nidus.


2020 ◽  
Author(s):  
Kil-yong Lee ◽  
Jaeim Lee ◽  
Youn Young Park ◽  
Seong Taek Oh

Abstract BACKGROUND Routine colonoscopy is recommended to determine the coexistence of colon cancer after medical treatment for colon diverticulitis. However, in the case of uncomplicated diverticulitis diagnosed by computed tomography imaging, the clinical relevance of routine follow-up colonoscopy has recently been debated. Yet, the role of follow-up colonoscopy for right colon diverticulitis, which tends to develop at a younger age than left colon diverticulitis, has not been specifically evaluated. Therefore, or aim in this study was to evaluate the incidence of colon cancer, detected by routine colonoscopy, after conservative management of acute uncomplicated right colon diverticulitis. METHODS Included were patients with uncomplicated right colon diverticulitis (modified Hinchey stage Ia) diagnosed by computed tomography imaging, between 2011 and 2017, and who underwent follow-up colonoscopy surveillance after treatment. The primary outcome was the incidence of colon cancer, with the detection rate of adenoma being the secondary outcome. Information for analysis was retrieved, retrospectively, from patients’ medical records. RESULTS The study group included 330 consecutive patients, with a mean age of 41.9 years, and 51.9% being men. For the primary outcome, the rate of colon cancer on follow-up colonoscopy was 0.3% (1/330 cases). The rate of adenoma detection was 20.3% (67/330 cases), with advanced adenoma identified in 9 of these cases (13.4%). CONCLUSION In patients with acute uncomplicated right colonic diverticulitis, routine colonoscopy after conservative treatment may not be necessary.


2014 ◽  
Vol 15 (13) ◽  
pp. 5111-5116 ◽  
Author(s):  
Kanabagatte Nanjundappa Manjunath ◽  
Prabhu Karkala Gopalakrishna ◽  
Puttappa Chandrappa Siddalingaswamy

2014 ◽  
Vol 32 (3_suppl) ◽  
pp. 408-408
Author(s):  
Bodil E. Engelmann ◽  
Annika Loft ◽  
Andreas Kjær ◽  
Hans J. Nielsen ◽  
Anne Kiil Berthelsen ◽  
...  

408 Background: Optimal management of colon cancer requires detailed assessment of extent of disease. Diagnostic accuracy of 18F-fluorodeoxyglucose (FDG) positron emission tomography/ computed tomography (PET/CT) in primary colon cancer staging and for detection of recurrence was investigated. Methods: PET/CT for preoperative staging was performed on 66 prospectively included patients with primary colon cancer. Diagnostic accuracy for PET/CT and CT alone was analysed. Forty-two stage I-III colon cancer patients had PET/CT follow-up examinations every six months for two years. Serological levels of Tissue Inhibitor of Metalloproteinases (TIMP-1), Carcinoembryonic Antigen (CEA), and liberated domain I of urokinase Plasminogen Activator Receptor [uPAR(I)] and FDG-uptake related tumour gene expression were analysed. Results: Accuracy for T-, N- and M-staging by PET/CT were 82 % [95% Confidence Interval (CI) 70; 91], 66 % [CI 51; 78] and 89 % [CI 79; 96]; for CT 77 % [CI 64; 87], 60 % [CI 46; 73] and 69 % [CI 57; 80]. Cumulative relapse incidences for stage I – III colon cancer at 6, 12, 18 and 24 months were 7.1 % [CI 0; 14.9]; 14.3 % [CI 3.7; 24.9]; 19.0 % [CI 7.1; 30.9] and 21.4 % [CI 9.0; 33.8]. PET/CT diagnosed all relapses detected during the first two postoperative years. High preoperative TIMP-1 levels were associated with significant hazards towards both risk of recurrence and shorter overall survival. FDG-uptake in colon cancer showed significant correlation to hexokinase 2, the hypoxia marker carboanhydrase IX and the proliferation marker ki67. Conclusions: This study indicates PET/CT to be a valuable tool for staging and follow-up in colon cancer. TIMP-1 provided prognostic information potentially useful in selection of patients for intensive follow-up.


2021 ◽  
Vol 8 (3) ◽  
pp. 1008
Author(s):  
Haitham A. Saimeh

Follow up post colorectal cancer treatment is the gold standard to detect early recurrence, since this improves the quality of patient’s lifestyle reducing the incidence of mortality and morbidity. Intensive follow up is usually reserved for patients with additional risk factors as older age, family history of colon cancer, underlying medical history of ulcerative colitis or chrons, obesity. Multidisciplinary team approach is currently used worldwide to accurately diagnose and stage the cancer, this provides great benefit to the patient’s outcome.


Sign in / Sign up

Export Citation Format

Share Document