scholarly journals A community-engaged protocol for evaluating environmental toxicants in a U.S. border community: the public health impacts of perchlorate and pesticide exposure (Preprint)

2019 ◽  
Author(s):  
Robert Trotter II ◽  
Julie Baldwin ◽  
Charles Loren Buck ◽  
Mark Remiker ◽  
Amanda Aguirre ◽  
...  

BACKGROUND The Northern Arizona University (NAU) Center for Health Equity Research (CHER) is conducting community-engaged health research “environmental toxicant scans” in the Yuma County (Yuma, Somerton, San Luis) regions in collaboration with community health stakeholders including the Yuma Regional Medical Center (YRMC), the Regional Center for Border Health, Inc. (RCBH), Campesinos sin Fronteras (CSF), the Yuma County Public Health District, and government agencies and NGO’s working on border health issues. OBJECTIVE We set out to construct a joint community/university effort to examine human exposures to the water-soluble contaminant perchlorate and to agricultural pesticides. This project includes development of a new animal model for investigation of mechanisms of toxicity following a “one health” approach. The ultimate goal of this community-engaged effort is to develop interventions to reduce exposures and health impacts of contaminants in Yuma populations. METHODS All participants completed the informed consent process, which included information on the purposes of the study, a request for access to health history and medical records data, and an interview. The interview included questions related to: 1) demographics, 2) social determinants of health, 3) health screening (e.g., family history of diseases), 4) occupation and environmental exposure to perchlorate and pesticides, and 5) access to health services. Each participant provided a hair sample for quantification of metals used in pesticides, a urine sample for perchlorate quantification, and a blood sample for endocrine assays. Data are modeled with measured levels of contaminants and hormones, and health status of the clinical population; data from the clinical population are compared to results from the general population. In parallel, an animal model for the impact of perchlorate and toxic metal exposure is being established through the collection of rodents that live near residences, farms, and local water sources. RESULTS We recruited, consented, enrolled, and surveyed 323 adults currently residing in Yuma County over a period of one year. One hundred and forty-seven residents are patients from either YRMC or RCBH with a primary diagnosis of thyroid disease, including hyperthyroidism, hypothyroidism, thyroid cancer, or goiter. The remaining 176 participants are from the general population but with no history of thyroid disorder. All participants completed the informed consent process, which included information on the purposes of the study, a request for access to health history and medical records data, and an interview. In parallel, an animal model for the impact of perchlorate and toxic metal exposure is being established through the collection of rodents that live near residences, farms, and local water sources. We are measuring perchlorate and toxic metals in tissues and examining the same health outcomes as with people (endocrine disruption), plus organ-specific histopathology, gene expression, and lipid accumulation. CONCLUSIONS Findings will elucidate mechanisms of toxicity and the population health effects of contaminants, as well as provide a new animal model to develop precision medicine capabilities for the population. CLINICALTRIAL not a clinical trial

2004 ◽  
Vol 118 (7) ◽  
pp. 487-488 ◽  
Author(s):  
S. Dietrich

Tinnitus, that is defined as ’ringing in the ear’, is and has probably always been a very common phenomenon in the health history of mankind. A variety of pathomechanisms for its onset has been proposed in the past and this trend sees no stopping. Precise pathomechanisms still remain unclear. From the historical point of view, tinnitus is a very interesting topic but there is a lack of scientific enquiries. As its earliest historic reference, the Papyrus Ebers is often cited. By reviewing the original source, however, it is very unlikely that this contains the earliest historic reference of tinnitus. It is rather likely indeed that tinnitus was a known symptom in the ancient Egypt but it has never been exclusively been written down. This article reviews data provided by this fascinating historical period on the questionable reference and highlights the impact of history on the modern status of tinnitus.


2018 ◽  
Vol 35 (1) ◽  
pp. 3-10 ◽  
Author(s):  
Morgan L. Machen ◽  
Hamilton C. Borden ◽  
Kenneth C. Hohmeier

Background: Negative psychosocial implications stemming from the presence of diabetes, known as diabetes distress, place people with diabetes at twice the likelihood of having clinical depression than those who do not have the disease. While many community pharmacies have incorporated diabetes self-management education (DSME) programs into their practices, there are no known studies that evaluate the impact that this model may have on diabetes distress. Objective: The purpose of this study is to evaluate the impact that a community pharmacy DSME program has on diabetes distress. Methods: Retrospective chart review for pre- and post-DSME Problem Areas in Diabetes scale scores, pertinent health history (type and duration of diabetes, A1C, and medications), and demographic information (age, gender) of patients who completed Blount Discount Pharmacy’s DSME program. Data were analyzed using descriptive and inferential statistics. Results: Of the 17 charts that were reviewed, there was an overall decrease in Problem Areas in Diabetes scale scores from baseline ( P = .029). Greater reduction was observed in patients with a long-standing history of diabetes compared with those who were diagnosed with diabetes within the previous 12 months of DSME. Conclusions: The findings suggest that a community pharmacy DSME program may reduce diabetes distress and warrant future study.


Author(s):  
Grant L. Iverson ◽  
Paul D. Berkner ◽  
Ross Zafonte ◽  
Bruce Maxwell ◽  
Douglas P. Terry

AbstractThis study examined the association between past concussions and current preseason symptom reporting and cognitive performance in 9,257 youth ages 11–13. Participants completed neurocognitive testing prior to participating in a school sports between 2009 and 2019. We stratified the sample by gender and number of prior concussions and assessed group differences on the Post-Concussion Symptom Scale total score and the ImPACT cognitive composite scores. Those with≥2 prior concussions reported more symptoms than those with 0 concussions (d=0.43–0.46). Multiple regressions examining the contribution of concussion history and developmental/health history to symptom reporting showed the most significant predictors of symptoms scores were (in descending order): treatment for a psychiatric condition, treatment for headaches, history of learning disability (in boys only), history of attention-deficit/hyperactivity disorder, and age. Concussion history was the weakest statistically significant predictor in boys and not significant in girls. Cognitively, boys with 1 prior concussion had worse speed those with 0 concussions (d=0.11), and girls with≥2 prior concussions had worse verbal/visual memory than girls with 0 concussions (ds=0.38–0.39). In summary, youth with≥2 prior concussions reported more symptoms than those with no concussions. Boys with multiple concussions performed similarly on cognitive testing, while girls had worse memory scores.


Author(s):  
Richard Tagne Simo ◽  
Carmelle Noubissie Cheunieu ◽  
Mohamadou Ahmadou ◽  
Erika Myriam Baiguerel ◽  
Armel Hervé Nwabo Kamdje ◽  
...  

Due to the lack of hospitals with adequate technical platform on one hand, and high diagnostic costs that cannot be afforded most of the population, the incidence of prostate cancer in Cameroon has increased and has great impact on people’s health. Aim: This work was undertaken with the objective to determine the impact of prostate cancer on erectile dysfunction and how to manage it. Methodology: Sampling of the population was done in a comprehensive and non-probabilistic manner at the Urology Department of Ngaoundere Islamic Hospital, Ngaoundere, Cameroon, between June 2018 and November 2019. Of the 75 patients received, 50 of them participated in this study. Biopsies were taken from these patients to determine and confirm the form and stage of cancer followed by PSA assays. After the diagnosis was revealed, the testosterone assay was carried out in order to evaluate erectile functioning in the patients who equally completed a survey form made available to them in order to get an idea of their health history, the type of treatment followed and their lifestyle. Results: The mean age of the patients was 67 years, with a predominance in the 60-70 age range. 85% of the patients had a Gleason score greater than or equal to 8. Of these patients, 42% had low testosterone levels (< 2.3 ng/mL), resulting to lack of morning erection (66.6%), loss of sexual desire (43.9%), difficulty having a spontaneous erection (88%). On the other hand, erectile dysfunction was revealed in the prostate cancer patients with low testosterone levels, with a history of hypertention (16.6%), diabetes (28.5%) alcohol consumption (44%), tobacco smoking (41%) and having undergone as prostate cancer treatment involving transurethral resection of the prostate (80%) and orchiectomy (20%). Conclusion: The major cause of erectile dysfunction observed in patients suffering from prostate cancer in Northen Cameroon can be attributed to the evolution of the disease, as well as the health history of the patients (diabetes, hypertension).


2004 ◽  
Vol 22 (1) ◽  
pp. 39-58 ◽  
Author(s):  
LINDA B. BOLTON ◽  
JOYCE NEWMAN GIGER ◽  
C. ALICIA GEORGES

Limited access to health care and a system fraught with discriminatory practices inhibit some racial and ethnic minorities from gaining access to health care and assurance of equal treatment once they enter the health care system. The purpose of this chapter is to critically and systematically analyze the research literature to determine what impact individual and institutional racism has had on the prevailing health disparities across racial and ethnic minority groups. The chapter includes the following: (1) a review of the term racism and a brief overview of the history of racism in health care; (2) a review of the research literature analyzing the impact of racism on health disparities; and (3) recommendations to end the systematic institutional racism in scientific research, which is necessary to end health disparities.


Crisis ◽  
2016 ◽  
Vol 37 (4) ◽  
pp. 265-270 ◽  
Author(s):  
Meshan Lehmann ◽  
Matthew R. Hilimire ◽  
Lawrence H. Yang ◽  
Bruce G. Link ◽  
Jordan E. DeVylder

Abstract. Background: Self-esteem is a major contributor to risk for repeated suicide attempts. Prior research has shown that awareness of stigma is associated with reduced self-esteem among people with mental illness. No prior studies have examined the association between self-esteem and stereotype awareness among individuals with past suicide attempts. Aims: To understand the relationship between stereotype awareness and self-esteem among young adults who have and have not attempted suicide. Method: Computerized surveys were administered to college students (N = 637). Linear regression analyses were used to test associations between self-esteem and stereotype awareness, attempt history, and their interaction. Results: There was a significant stereotype awareness by attempt interaction (β = –.74, p = .006) in the regression analysis. The interaction was explained by a stronger negative association between stereotype awareness and self-esteem among individuals with past suicide attempts (β = –.50, p = .013) compared with those without attempts (β = –.09, p = .037). Conclusion: Stigma is associated with lower self-esteem within this high-functioning sample of young adults with histories of suicide attempts. Alleviating the impact of stigma at the individual (clinical) or community (public health) levels may improve self-esteem among this high-risk population, which could potentially influence subsequent suicide risk.


Author(s):  
C. Claire Thomson

This chapter traces the early history of state-sponsored informational filmmaking in Denmark, emphasising its organisation as a ‘cooperative’ of organisations and government agencies. After an account of the establishment and early development of the agency Dansk Kulturfilm in the 1930s, the chapter considers two of its earliest productions, both process films documenting the manufacture of bricks and meat products. The broader context of documentary in Denmark is fleshed out with an account of the production and reception of Poul Henningsen’s seminal film Danmark (1935), and the international context is accounted for with an overview of the development of state-supported filmmaking in the UK, Italy and Germany. Developments in the funding and output of Dansk Kulturfilm up to World War II are outlined, followed by an account of the impact of the German Occupation of Denmark on domestic informational film. The establishment of the Danish Government Film Committee or Ministeriernes Filmudvalg kick-started aprofessionalisation of state-sponsored filmmaking, and two wartime public information films are briefly analysed as examples of its early output. The chapter concludes with an account of the relations between the Danish Resistance and an emerging generation of documentarists.


Author(s):  
Bryan D. Palmer

This article is part of a special Left History series reflecting upon changing currents and boundaries in the practice of left history, and outlining the challenges historians of the left must face in the current tumultuous political climate. This series extends a conversation first convened in a 2006 special edition of Left History (11.1), which asked the question, “what is left history?” In the updated series, contributors were asked a slightly modified question, “what does it mean to write ‘left’ history?” The article charts the impact of major political developments on the field of left history in the last decade, contending that a rising neoliberal and right-wing climate has constructed an environment inhospitable to the discipline’s survival. To remain relevant, Palmer calls for historians of the left to develop a more “open-ended and inclusive” understanding of the left and to push the boundaries of inclusion for a meaningful historical study of the left. To illustrate, Palmer provides a brief materialist history of liquorice to demonstrate the mutability of left history as a historical approach, rather than a set of traditional political concerns.


2020 ◽  
Vol 5 (3) ◽  
pp. 20-24
Author(s):  
Durdona Karimova ◽  

This article discusses the theoretical and practical foundations of the concept of sociolinguistics and the importance of this field in the study of the impact of society on language. It also describes the views of linguists in this regard, the history of the origin and development of the filed, its connection with other disciplines, and explains in detail the sociolinguistic issues with practical examples.In addition, the terms as macro-sociolinguistics and micro-sociolinguistics and sociolinguistic competence are explained.


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