scholarly journals Toward Evidence-Based Decision Aids for Patients with Parkinson’s Disease: Protocol for an Interview Study, an Online Survey, and two Randomized Controlled Trials (Preprint)

10.2196/17482 ◽  
2019 ◽  
Author(s):  
Martina Bientzle ◽  
Joachim Kimmerle ◽  
Marie Eggeling ◽  
Idil Cebi ◽  
Daniel Weiss ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Randomized Controlled Trials ◽  
Online Survey ◽  
Decision Aids ◽  
Interview Study ◽  
Controlled Trials ◽  
Evidence Based ◽  
Randomized Controlled

scholarly journals Additional Physical Interventions to Conventional Physical Therapy in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

2020 ◽  
Vol 9 (4) ◽  
pp. 1038 ◽  
Author(s):  
Ruben D. Hidalgo-Agudo ◽  
David Lucena-Anton ◽  
Carlos Luque-Moreno ◽  
Alberto Marcos Heredia-Rizo ◽  
Jose A. Moral-Munoz
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Physical Therapy ◽  
Randomized Controlled Trials ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Balance Confidence ◽  
Randomized Controlled

Parkinson’s disease (PD) represents the second most common neurodegenerative disease. Currently, conventional physical therapy is complemented by additional physical interventions with recreational components, improving different motor conditions in people with PD. This review aims to evaluate the effectiveness of additional physical interventions to conventional physical therapy in Parkinson’s disease. A systematic review and meta-analysis of randomized controlled trials were performed. The literature search was conducted in PubMed, Physiotherapy Evidence Database (PEDro), Scopus, SciELO and Web of Science. The PEDro scale was used to evaluate the methodological quality of the studies. A total of 11 randomized controlled trials were included in this review. Five of them contributed information to the meta-analysis. The statistical analysis showed favorable results for dance-based therapy in motor balance: (Timed Up and Go: standardized mean difference (SMD) = −1.16; 95% Confidence Interval (CI):(−2.30 to −0.03); Berg Balance Scale: SMD = 4.05; 95%CI:(1.34 to 6.75)). Aquatic interventions showed favorable results in balance confidence (Activities-Specific Balance Confidence: SMD=10.10; 95%CI:(2.27 to 17.93)). The results obtained in this review highlight the potential benefit of dance-based therapy in functional balance for people with Parkinson’s disease, recommending its incorporation in clinical practice. Nonetheless, many aspects require clarification through further research and high-quality studies on this subject.

Cardiovascular Adverse Events Reported in Placebo Arm of Randomized Controlled Trials in Parkinson’s Disease

2020 ◽  
Vol 10 (2) ◽  
pp. 641-651
Author(s):  
Mariana Alves ◽  
Daniel Caldeira ◽  
Miguel Leal Rato ◽  
Gonçalo S. Duarte ◽  
Afonso N. Ferreira ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Adverse Events ◽  
Randomized Controlled Trials ◽  
Controlled Trials ◽  
Randomized Controlled

Deep brain stimulation in Parkinson’s disease: meta-analysis of randomized controlled trials

2014 ◽  
Vol 261 (11) ◽  
pp. 2051-2060 ◽  
Author(s):  
L. Perestelo-Pérez ◽  
A. Rivero-Santana ◽  
J. Pérez-Ramos ◽  
P. Serrano-Pérez ◽  
J. Panetta ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Randomized Controlled Trials ◽  
Brain Stimulation ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Deep Brain
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