scholarly journals The Psychosocial Impact of Hearing Loss on the Quality of life in Adults with Multi-Drug Resistant Tuberculosis (Preprint)

10.2196/16075 ◽  
2019 ◽  
Author(s):  
Amanda Thusi ◽  
Jessica Paken
Keyword(s):  
Quality Of Life ◽  
Hearing Loss ◽  
Psychosocial Impact ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis

scholarly journals The Psychosocial Impact of Hearing Loss on the Quality of life in Adults with Multi-Drug Resistant Tuberculosis (Preprint)

2019 ◽  
Author(s):  
Amanda Thusi ◽  
Jessica Paken
Keyword(s):  
Quality Of Life ◽  
Health Care ◽  
Hearing Loss ◽  
Well Being ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis ◽  
Mdr Tb

BACKGROUND Aminoglycoside treatment used for MDR-TB is likely to result in ototoxicity. The effects of a hearing loss with a MDR-TB diagnosis are likely to have an increased impact on the overall quality of life of an individual. However, there is minimal research in the area, which would therefore indicate a possible lack of awareness to the effect of aminoglycoside treatment on the quality of life of patients. While most studies on drug resistant TB are focused on the public health concerns of the disease, the human costs of MDR-TB are sometimes overlooked. OBJECTIVE This study aims to describe the psychological, social, economic and vocational impact of hearing loss on the quality of life of adults with Multi-Drug Resistant Tuberculosis. METHODS A Qualitative Phenomenological research study will be conducted on 10 participants. All participants will have a laboratory confirmed diagnosis of Multi-Drug Resistant Tuberculosis. A semi-structured interview questionnaire will be used to collect data. Face-to-face interviews will be conducted and the participants will be audio recorded. All interviews will be conducted by the researcher. RESULTS The study has not concluded. CONCLUSIONS The quality of life of a patient needs to be considered in the health care system during treatment, as this data may drive improved national health care planning with regards to treatment of patients diagnosed with MDR-TB. Therefore, for a comprehensive assessment of patient’s health status, it is very much essential to assess the overall impact of MDR-TB on health and patient’s perception of well-being. Besides routine clinical and bacteriological assessments, this assessment can be done by assessing quality of life which has several domains. Patients diagnosed with MDR-TB who further acquire an aminoglycoside induced hearing loss may have life-long effects on their quality of life even after completion of treatment.

scholarly journals Gambaran Kualitas Hidup Penderita Tuberkulosis Resistan Obat dan Karakteristiknya di Kabupaten Banyumas, Provinsi Jawa Tengah, Periode Tahun

2018 ◽  
Vol 34 (2) ◽  
pp. 55
Author(s):  
Imam Abrori ◽  
Riris Andono Ahmad
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Low Income ◽  
Basic Education ◽  
Skills Training ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis

Quality of life among patients with multi-drug resistant tuberculosis in the district of BanyumasPurposeThis study was conducted to investigate the quality of life among patients with multi-drug resistant tuberculosis and to examine factors associated with them. MethodsData from an in-depth interview, involved 22 patients with multi-drug resistant tuberculosis, were used in this study. ResultsThis study showed 54.5% males, 50.0% adults, 59.1% married, 22.7% divorced, 72.7% lived in rural, 95.5% had basic education, 45.5% as a private employment (before sick), 77.3% as unemployment (after sick), 72.7% low income, 54.5% in continuation phase, 95.5%  re-treatment (45% relapse and 40.9% failure cases), 90.9% had drugs side effects (mild/severe); 36.4% had comorbidity; 45.5% smokers, 31.8% falcoholics; 54.5% lack of social support; 31.8% poor and 36.4% moderate quality of life. ConclusionPatients with multi-drug resistant tuberculosis had a worse quality of life and lack social support. Health worker needs to improve their quality of life and social support through establishing a peer support groups to give counseling, information education, communication, motivation, and skills training for them.

scholarly journals Neuropsychiatric reactions induced by cycloserine in the treatment of multidrug-resistant tuberculosis: what an Indian female patient tells us

2019 ◽  
Vol 12 (12) ◽  
pp. e230993 ◽  
Author(s):  
Enrica Intini ◽  
Girija Kishore ◽  
Luca Richeldi ◽  
Zarir F Udwadia
Keyword(s):  
Adverse Events ◽  
Multidrug Resistant ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Health Crisis ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis ◽  
Group B

Multidrug-resistant tuberculosis continues to be a public health crisis. Urgent action is required to improve the coverage and quality of diagnosis, treatment and care for people affected by drug-resistant tuberculosis. To implement tuberculosis control, in 2018, WHO recommended cycloserine as one of the Group B drugs. Following this recommendation, cycloserine should be generally included in the starting line-up in the longer regimen for the treatment of multidrug-resistant tuberculosis. However, neurological toxicity associated with this drug concerns clinicians and limits its use. In this paper, we present a case of a 48-year-old woman with a diagnosis of multidrug-resistant tuberculosis treated with cycloserine, who developed psychiatric adverse events after 3 months of administration. This case shows the need for close psychiatric follow-up to promptly detect adverse events in patients receiving regimens for multi-drug resistant tuberculosis.

scholarly journals Pharmacokinetics and other risk factors for kanamycin-induced hearing loss in patients with multi-drug resistant tuberculosis

2019 ◽  
Vol 59 (3) ◽  
pp. 219-223
Author(s):  
Nazanin Ghafari ◽  
Richard Court ◽  
Maxwell Tawanda Chirehwa ◽  
Lubbe Wiesner ◽  
Lucretia Petersen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hearing Loss ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis

scholarly journals Clinical Guidelines for Managing Hearing Loss as a Complication of Drug-Resistant Tuberculosis Treatment: An Evaluation of Implementation fidelity in Kano, Nigeria

2021 ◽  
Author(s):  
Sani Ibrahim Muhammad ◽  
Ejemai Amaize Eboreime ◽  
Vivian Ifeoma Ogbonna ◽  
Iliyasu Zubairu ◽  
Latifat Ibisomi
Keyword(s):  
Hearing Loss ◽  
Work Experience ◽  
Implementation Fidelity ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Management Guidelines ◽  
Tb Treatment ◽  
Resistant Tuberculosis ◽  
Quality Of Delivery

Abstract Background: Nigeria has a high burden of Tuberculosis (TB) including Drug-resistant Tuberculosis (DR-TB) and hearing lossObjective: To measure the implementation fidelity of management guidelines for hearing loss resulting from DR-TB treatment and to identify its determinants Method: A questionnaire-based cross-sectional study was conducted at the Infectious Disease Hospital, Kano. Implementation fidelity of the Programmatic Management guidelines for the treatment of Drug-resistant Tuberculosis was measured under the four domains of content, coverage, duration and frequency. The determinants examined are intervention complexity, facilitation strategies, quality of delivery and participant responsiveness as proposed by the Carroll et al framework. Other determinants used are age, sex, professional cadre and work experience of healthcare providers.Results: The Implementation fidelity score ranged from 40 - 64% with a mean of 47.6%. Quality of delivery, intervention complexity, participants’ responsiveness, and being a medical doctor exerted a positive effect on implementation fidelity while facilitation strategy, age and work experience exerted a negative effect on implementation fidelity. Conclusion: The implementation fidelity of management guidelines for hearing loss resulting from DR-TB treatment was low. Implementation fidelity should be assessed early and at intervals in the course of implementing the PMDT guideline and indeed, in the implementation of any intervention.

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