scholarly journals Medication Use for Childhood Pneumonia at a Children’s Hospital in Shanghai, China: Analysis of Pattern Mining Algorithms

10.2196/12577 ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. e12577
Author(s):  
Chunlei Tang ◽  
Huajun Sun ◽  
Yun Xiong ◽  
Jiahong Yang ◽  
Christopher Vitale ◽  
...  
Keyword(s):  
Pattern Mining ◽  
Medication Use ◽  
Childhood Pneumonia ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Mining Algorithms

scholarly journals Medication Use for Childhood Pneumonia at a Children’s Hospital in Shanghai, China: Analysis of Pattern Mining Algorithms (Preprint)

2018 ◽  
Author(s):  
Chunlei Tang ◽  
Huajun Sun ◽  
Yun Xiong ◽  
Jiahong Yang ◽  
Christopher Vitale ◽  
...  
Keyword(s):  
Pattern Mining ◽  
Skin Diseases ◽  
Medication Use ◽  
Medication Administration ◽  
Treatment Patterns ◽  
Childhood Pneumonia ◽  
Children's Hospital ◽  
Use Patterns ◽  
Medication Use Patterns ◽  
Mining Algorithms

BACKGROUND Pattern mining utilizes multiple algorithms to explore objective and sometimes unexpected patterns in real-world data. This technique could be applied to electronic medical record data mining; however, it first requires a careful clinical assessment and validation. OBJECTIVE The aim of this study was to examine the use of pattern mining techniques on a large clinical dataset to detect treatment and medication use patterns for childhood pneumonia. METHODS We applied 3 pattern mining algorithms to 680,138 medication administration records from 30,512 childhood inpatients with diagnosis of pneumonia during a 6-year period at a children’s hospital in China. Patients’ ages ranged from 0 to 17 years, where 37.53% (11,453/30,512) were 0 to 3 months old, 86.55% (26,408/30,512) were under 5 years, 60.37% (18,419/30,512) were male, and 60.10% (18,338/30,512) had a hospital stay of 9 to 15 days. We used the FP-Growth, PrefixSpan, and USpan pattern mining algorithms. The first 2 are more traditional methods of pattern mining and mine a complete set of frequent medication use patterns. PrefixSpan also incorporates an administration sequence. The newer USpan method considers medication utility, defined by the dose, frequency, and timing of use of the 652 individual medications in the dataset. Together, these 3 methods identified the top 10 patterns from 6 age groups, forming a total of 180 distinct medication combinations. These medications encompassed the top 40 (73.66%, 500,982/680,138) most frequently used medications. These patterns were then evaluated by subject matter experts to summarize 5 medication use and 2 treatment patterns. RESULTS We identified 5 medication use patterns: (1) antiasthmatics and expectorants and corticosteroids, (2) antibiotics and (antiasthmatics or expectorants or corticosteroids), (3) third-generation cephalosporin antibiotics with (or followed by) traditional antibiotics, (4) antibiotics and (medications for enteritis or skin diseases), and (5) (antiasthmatics or expectorants or corticosteroids) and (medications for enteritis or skin diseases). We also identified 2 frequent treatment patterns: (1) 42.89% (291,701/680,138) of specific medication administration records were of intravenous therapy with antibiotics, diluents, and nutritional supplements and (2) 11.53% (78,390/680,138) were of various combinations of inhalation of antiasthmatics, expectorants, or corticosteroids. Fleiss kappa for the subject experts’ evaluation was 0.693, indicating moderate agreement. CONCLUSIONS Utilizing a pattern mining approach, we summarized 5 medication use patterns and 2 treatment patterns. These warrant further investigation.

A Clinical Evaluation of Pivampicillin in Childhood Pneumonia

1977 ◽  
Vol 5 (5) ◽  
pp. 330-333
Author(s):  
Ashfaq Alam Khan
Keyword(s):  
Clinical Trial ◽  
Clinical Evaluation ◽  
Drug Toxicity ◽  
University Teaching ◽  
Specific Drug ◽  
Childhood Pneumonia ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Discharge From Hospital ◽  
The University

A clinical trial was done at the University Teaching (Children's) Hospital on 20 children suffering from clinical pneumonias with a specific drug regime with pivampicillin suspension. Every child was re-examined after 7-10 days of discharge from hospital. Only one child developed diarrhoea. There was no significant adverse drug toxicity shown in the biomedical investigations. Pivampicillin, three times a day at a dosage of 175 mg t.d.s. was found to be therapeutically effective in the treatment of childhood pneumonias.

Pattern of Medication Use and Errors in a Tertiary Care Children's Hospital Intensive Care Unit

2006 ◽  
Vol 22 (6) ◽  
pp. 326-331 ◽  
Author(s):  
Ilyas Burny ◽  
Mary W Lieh-Lai ◽  
Ken N Gaynor ◽  
Ronald L Thomas ◽  
Ashok P Sarnaik
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Tertiary Care ◽  
Medication Use ◽  
Children's Hospital ◽  
Hospital Intensive Care Unit ◽  
Children’S Hospital

Passy-Muir Speaking Valve Use in a Children's Hospital: An Interdisciplinary Approach

2008 ◽  
Vol 18 (2) ◽  
pp. 76-86 ◽  
Author(s):  
Lauren Hofmann ◽  
Joseph Bolton ◽  
Susan Ferry
Keyword(s):  
Tracheostomy Tube ◽  
Pediatric Population ◽  
Interdisciplinary Approach ◽  
Extended Period ◽  
Speech Development ◽  
Tube Placement ◽  
Background Information ◽  
Speaking Valve ◽  
Children's Hospital ◽  
Children’S Hospital

Abstract At The Children's Hospital of Philadelphia (CHOP) we treat many children requiring tracheostomy tube placement. With potential for a tracheostomy tube to be in place for an extended period of time, these children may be at risk for long-term disruption to normal speech development. As such, speaking valves that restore more normal phonation are often key tools in the effort to restore speech and promote more typical language development in this population. However, successful use of speaking valves is frequently more challenging with infant and pediatric patients than with adult patients. The purpose of this article is to review background information related to speaking valves, the indications for one-way valve use, criteria for candidacy, and the benefits of using speaking valves in the pediatric population. This review will emphasize the importance of interdisciplinary collaboration from the perspectives of speech-language pathology and respiratory therapy. Along with the background information, we will present current practices and a case study to illustrate a safe and systematic approach to speaking valve implementation based upon our experiences.

Children’s Hospital of Eastern Ontario Pain Scale

1985 ◽  
Author(s):  
Patrick J. McGrath ◽  
Garry Johnson ◽  
John T. Goodman ◽  
John Schillinger ◽  
Jennifer Dunn ◽  
...  
Keyword(s):  
Pain Scale ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Eastern Ontario

Children's Hospital of Philadelphia—Self-Efficacy Scale--Spanish Version

2018 ◽  
Author(s):  
Anne E. Kazak ◽  
Wei-Ting Hwang ◽  
Fang Fang Chen ◽  
Martha A. Askins ◽  
Olivia Carlson ◽  
...  
Keyword(s):  
Self Efficacy ◽  
Spanish Version ◽  
Children's Hospital ◽  
Children’S Hospital
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