scholarly journals Effectiveness of Low Glycemic Index Diet Consultations Through a Diet Glycemic Assessment App Tool on Maternal and Neonatal Insulin Resistance: A Randomized Controlled Trial

10.2196/12081 ◽  
2019 ◽  
Vol 7 (4) ◽  
pp. e12081 ◽  
Author(s):  
Yi Zhang ◽  
Liping Wang ◽  
Wenhong Yang ◽  
Dayan Niu ◽  
Chunying Li ◽  
...  
2021 ◽  
Vol 171 ◽  
pp. 106574
Author(s):  
Kannan Lakshminarayanan ◽  
Anuja Agarawal ◽  
Prateek Kumar Panda ◽  
Rahul Sinha ◽  
Manjari Tripathi ◽  
...  

2019 ◽  
Vol 28 (2) ◽  
pp. 123-8 ◽  
Author(s):  
Agustini Utari ◽  
Muhammad Saifulhaq Maududi ◽  
Ninung Rose Diana Kusumawati ◽  
Maria Mexitalia

BACKGROUND Obesity is strongly correlated with insulin resistance (IR) and nonalcoholic fatty liver disease (NAFLD). Some studies suggest that dietary intake with low glycemic index (GI) may prevent IR and reduce the incidences of NAFLD. This study was aimed to determine the effects of low GI diet on IR among obese adolescents with NAFLD. METHODS This study was a randomized controlled trial conducted in two JuniorHigh Schools in Semarang, Indonesia. The subjects were 12–14 years obese students with NAFLD, which divided into intervention and control groups according to schools using block random allocation. The intervention group received nutrition education and lunch diet (low energy, low GI, and low fat); meanwhile, the control group only received nutrition education for 12 weeks. The biochemical evaluation included fasting blood glucose (FBG) and insulin levels. IR was assessed using homeostatic model assessment-insulin resistance (HOMA-IR). RESULTS Thirty-two subjects were enrolled in this study, 16 of which were assigned to the intervention group and the other to the control group. After 12 weeks, the energy and carbohydrate intake reduced in the intervention group (p < 0.05), FBG remained unchanged, and HOMA-IR increased (4.9 [3.7]–7.2 [3.5]) compared to the control group (6.4 [4.9]–5.5 [2.8]) (p < 0.05). Meanwhile, within the control group, there were no significant differences in the energy and carbohydrate intake as well as biochemical variables. CONCLUSIONS Low GI modification diet alone may not reduce IR in the obeseadolescents with NAFLD.


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