scholarly journals The Association Between Paranasal Mucous Retention Cysts and Allergic Sensitization

2021 ◽  
Vol 19 (2) ◽  
pp. 57-63
Author(s):  
Feyza Ustabaş Kahraman ◽  
Mebrure Yazıcı ◽  
Nur Büyükpınarbaşılı ◽  
Nihal Soylu ◽  
Akın İşcan ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Pediatric Population ◽  
Allergic Sensitization ◽  
Blood Eosinophil ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Allergic Rhinitis Symptom ◽  
Rhinitis Symptom ◽  
Mri Scans ◽  
Retention Cysts

ABSTRACT Objective: Although there is no consensus regarding the etiology of paranasal mucous retention cysts (MRCs) in the literature, several studies suggest an allergic etiology. This study aimed to investigate a potential association between paranasal MRCs diagnosed with MRI scans and allergic sensitization in the pediatric population. Materials and Methods: A total of 4559 MRI scans were retrospectively evaluated for MRC in patients who presented to the pediatric neurology outpatient clinic with headache complaints. Fifty children with MRI findings conclusive for paranasal MRC and 50 children without such findings were included in the study. All study and control patients were invited for atopy/allergy evaluation. Total IgE measurements, blood eosinophil levels, nasal smear and skin prick tests were performed to evaluate the allergic status of the children. In addition, an allergic rhinitis symptom questionnaire was administered. Results: The mean age was 13.0±2.8 years (median 14 y, range 6-18 y) with a female-to-male ratio of 1.4:1 in the study group. The prevalence of MRC was found to be 1.1% (50 in 4559). The two groups did not differ with regard to the frequency of blood eosinophilia, nasal eosinophilia, serum IgE levels, and allergic rhinitis symptom severity (p>0.05). Positive skin test for at least one of the allergens tested was more common in the MRC group than the controls (40% vs. 16%, p=0.007). Multivariate analysis identified that a positive skin prick test for at least one allergen was a significant independent predictor of MRC (OR, 4.6; 95% CI 1.2-17.0, p=0.023). Conclusion: Our study showed that paranasal MRCs were significantly more frequent in atopic children compared to controls. Additionally, MRCs were found to be strongly associated with allergic sensitization. Keywords: Cysts, allergic rhinitis, children, diagnostic tests, signs and symptoms

Increased Nasal Eosinophils in Children with Otitis Media with Effusion

1996 ◽  
Vol 115 (5) ◽  
pp. 454-457
Author(s):  
Carlo Caffarelu ◽  
Giovanni Cavagni ◽  
Salvatore Giordano ◽  
Enrico Savini ◽  
Giorgio Piacentini
Keyword(s):  
Allergic Rhinitis ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Allergic Sensitization ◽  
Control Group ◽  
Positive Skin Prick Test ◽  
Healthy Children ◽  
Positive Skin ◽  
Prick Test ◽  
Nasal Cytology

The pathogenesis of otitis media with effusion is still under debate, but allergic sensitization has been suggested in some cases. We investigated whether nasal cytology may indicate an allergic pathogenesis for otitis media with effusion. Atopic symptoms, results of skin prick tests to common aeroallergens, and nasal cytology by nasal scraping were evaluated in 40 children with current otitis media with effusion and compared with findings in a group of 40 healthy children. The presence of nasal eosinophils was significantly more frequent in children with otitis media with effusion than in the control group ( p < 0.05). Nasal eosinophils were significantly associated with both allergic rhinitis ( p < 0.001) and positive skin prick test results ( p < 0.001). Allergic rhinitis with nasal eosinophilla was found in six children of the study group and in one child of the control group ( p < 0.05). Our data suggest that nasal allergic Inflammation may play a role in a subset of patients with otitis media with effusion. Therefore the possibility of allergic sensitization must always be considered in patients with serous otitis media.

scholarly journals Incidence of sensitization to specific inhalatory allergens in patients suffering from allergic rhinitis

2019 ◽  
Vol 76 (1) ◽  
pp. 50-54
Author(s):  
Maja Buljcik-Cupic ◽  
Slobodan Savovic ◽  
Sanja Hromis ◽  
Slobodanka Lemajic-Komazec ◽  
Dea Karaba-Jakovljevic
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Allergic Sensitization ◽  
Positive Skin Prick Test ◽  
Indoor Allergens ◽  
Positive Skin ◽  
Prick Test ◽  
Chronic Rhinitis ◽  
Frequent Type ◽  
Number Of Patients

Backgound/Aim. Allergic rhinitis is the most frequent type of rhinitis affecting more than 600 million people worldwide. As incidence increases, it is important to know about the characteristics, the allergens that exacerbate it as well as effects of allergic rhinitis on population. The aim of this study was to determine among patients with chronic rhinitis the number of patients positive to standard inhaled allergens, their distribution by sex, age and to determine the type and frequency of allergic sensitization to specific inhalatory allergens. Methods. Data was collected from 514 patients tested for standard inhalatory allergens via the skin prick test from 01.01.2016 to 31.12. 2016. Age, sex and concomitant diseases as well an analysis of type and frequency of hypersensitivity to different allergens were assessed and recorded. Results. Of 514 patients, 307 patients, with an average age of 29.6 ? 8.88 years had a positive skin prick test. The sex ratio was 1.2 : 1 in favor of the females. Outdoor allergens affected 81.2% of all patients while indoor allergens 66.4% of them. Weed pollen (71%), grass pollen (61%) and Dermatophagoides pteronyssinus (46%) were the most common allergens. Most patients were sensitized to 1 (22%) or 2 (22%) allergens, while 20% of patients were simultaneously sensitized to 3 allergens. Conclusion. Most patients with the symptoms of chronic rhinitis had a positive allergic reaction. Those in their third decade of life were the most commonly affected. Outdoor allergens were the most prevalent allergen group, and weed pollen was the most frequent type of allergen.

scholarly journals Immunotherapy in Allergic Rhinitis: It’s Effect on the Immune System and Clinical Symptoms

2018 ◽  
Vol 6 (7) ◽  
pp. 1248-1252 ◽  
Author(s):  
Samaneh Kouzegaran ◽  
Mohammad Ali Zamani ◽  
Reza Faridhosseini ◽  
Houshang Rafatpanah ◽  
Abdolrahim Rezaee ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Symptoms ◽  
Nasal Congestion ◽  
Subcutaneous Immunotherapy ◽  
Positive Skin Prick Test ◽  
Tgf Beta ◽  
Positive Skin ◽  
Ifn Gamma ◽  
Clinical Criteria ◽  
Prick Test

BACKGROUND: Allergic rhinitis is one of the most common allergic diseases and characterised by sneezing, rhinorrhea, nasal congestion and nasopharyngeal itching. Subcutaneous immunotherapy (SCIT) for specific allergens is an effective treatment and induces the inhibitory effect of T regulatory lymphocytes and decreases clinical symptoms in allergic rhinitis.AIM: In this study effect of subcutaneous immunotherapy with specific allergens on clinical symptoms and T regulatory and T Helper cells cytokines, in patients with allergic rhinitis are evaluated.METHODS: In this study, 30 patients with moderate to severe allergic rhinitis according to clinical criteria and positive skin prick test for aeroallergens were selected and treated by SCIT. Clinical symptoms and T cells cytokines IL4, IL17, IFN gamma, TGF beta, GITR, FOXP3 and IL-10 (by RT-PCR) were evaluated before and one year after initiation of treatment.RESULTS: Thirty (30) patients with allergic rhinitis at age range 15-45 years old were treated by SCIT, and 23 (14 female, 9 male) patients continued the study, and 7 patients did not continue treatment. After immunotherapy, clinical symptoms decreased significantly. The specific cytokines TGF beta and IL10 levels increased and changes were statistically significant. (Respectively P = 0.013 and P = 0.05) The IL17 level was also increased, but not statistically significant. (P = 0.8) IFN gamma, IL4, GITR, FOXP3, all decreased, but the changes were not statistically significant (P > 0.05).CONCLUSION: Subcutaneous Immunotherapy for specific allergens decreases clinical symptoms in patients with allergic rhinitis and induces tolerance in T lymphocytes, especially by increasing T regulatory cells cytokines, TGF beta and IL10.

Blood and nasal epigenetics correlate with allergic rhinitis symptom development in the environmental exposure unit

Allergy ◽  
2017 ◽  
Vol 73 (1) ◽  
pp. 196-205 ◽  
Author(s):  
M. L. North ◽  
M. J. Jones ◽  
J. L. MacIsaac ◽  
A. M. Morin ◽  
L. M. Steacy ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Environmental Exposure ◽  
Symptom Development ◽  
Environmental Exposure Unit ◽  
Allergic Rhinitis Symptom ◽  
Rhinitis Symptom

scholarly journals Soy Skin Prick Test in Patients with Physician-Diagnosed Atopic Disorders

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
S M Reda ◽  
N M Radwan ◽  
H R Abdelghany
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Soy Protein ◽  
Total Serum ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Female Ratio ◽  
Serum Ige ◽  
Prick Test ◽  
Protein Sensitization

Abstract Background Soy protein is an important component of soybeans and is one the 8 most significant food allergens. Yet, the prevalence of soy allergy in the pediatric population is not well defined. Objectives To evaluate the incidence of IgE mediated soy protein sensitization among children with clinical manifestation of atopic disorders by the use of skin prick test (SPT) for soy protein. Methods Two hundred patients with atopic manifestations attending the Pediatric Allergy and Immunology Clinic at the Pediatric Department of Ain shams University, were recruited between January 2017 till January 2018. They were subjected to SPT to soy protein, measurement of total serum IgE and eosinophilic count in the peripheral blood. Results Of the 200 patients, 108 (54%) were males and 92 (46%) were females with a male to female ratio of 1.17:1. Their ages ranged between 2 years and 15 years (mean±SD; 6.0±33.3 years). Seven patients (3.5%) had positive skin prick test to soy protein. The mean value for the absolute eosinophilic count was 0.4x109/L. The median for the total serum IgE level was 50 IU/L. According to age, the highest percentage of soy protein sensitivity was elicited among patients less than 3 years (57.14%), followed by those between 3 to 6 years (28.5%) and those between 6 and 15 years (14.28%). A positive family history of atopy was recorded in 122 (61%) of all cases. In terms of gender, incidence of soya sensitivity was higher among males than females but with no statistical difference. Although the most common allergic manifestations of all studied patients were respiratory (83%), and atopic dermatitis (22.5%), yet positive SPT to soy proteins was elicited in 43% in allergic rhinitis cases, in 29% of asthma patients, in 14% of patients with combined asthma and allergic rhinitis, and 14.3% of patients having eczema. Conclusion Soy protein sensitization is not uncommon in children especially in those with atopic manifestations. Large scale studies are needed to evaluate the actual incidence of soy protein hypersensitivity in children.

The effect of allergic rhinitis with positive skin prick test on choroidal thickness

2017 ◽  
Vol 274 (6) ◽  
pp. 2477-2481
Author(s):  
Alper Yenigun ◽  
Ahmet Elbay ◽  
Remzi Dogan ◽  
Orhan Ozturan ◽  
Mehmet Hakan Ozdemir
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Choroidal Thickness ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Prick Test

scholarly journals Does unified allergic airway disease impact on lung function and type 2 biomarkers?

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Chris RuiWen Kuo ◽  
Rory Chan ◽  
Brian Lipworth
Keyword(s):  
Allergic Rhinitis ◽  
Lung Function ◽  
Allergic Asthma ◽  
Asthma Control ◽  
Persistent Asthma ◽  
Airway Disease ◽  
Allergic Airway Disease ◽  
Positive Skin Prick Test ◽  
Positive Skin

AbstractThe concept of the unified allergic airway disease (UAD) recognises the association between allergic inflammation in the upper and lower airways. Patients with asthma and concomitant allergic rhinitis experience more asthma-related primary and secondary care visits. We therefore aimed to determine differences in asthma control (asthma control questionnaire ACQ-6), lung function (spirometry) and T2 biomarkers (FeNO and Eos) in relation to the presence of allergic rhinitis in patients with allergic asthma. Retrospectively, we evaluated a cohort of 60 consecutive patients with persistent asthma attending our research unit for screening into clinical trials. All included subjects were receiving inhaled corticosteroids (ICS) and had a positive skin prick test (SPT) to at least one common aeroallergen to fulfil the criterion of allergic asthma. Patients with UAD had a diagnosis of allergic asthma in addition to established concomitant allergic rhinitis. T2 biomarkers were significantly higher in patients with allergic rhinitis in contrast to those without. FEV1 % predicted and FEF25-75 % predicted were also significantly lower in patients with concomitant allergic rhinitis. However, there was no difference in ACQ-6 observed between groups. In summary, patients with allergic asthma, the presence of concomitant allergic rhinitis is associated with worse lung function and higher type 2 biomarkers.

scholarly journals Effect of salivary secretion with mouthguard use on seasonal allergic rhinitis symptom improvement

2020 ◽  
Vol 62 (2) ◽  
pp. 205-211
Author(s):  
Nobuyuki Tani-Ishii ◽  
Koichiro Muromachi ◽  
Noriko Mutoh ◽  
Jiro Suzuki ◽  
Kaori Shimojima ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Seasonal Allergic Rhinitis ◽  
Salivary Secretion ◽  
Symptom Improvement ◽  
Allergic Rhinitis Symptom ◽  
Rhinitis Symptom
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