scholarly journals The effect of Glycoline® on reproductive efficiency in high-producing dairy cows

2016 ◽  
pp. 5163-5176
Author(s):  
Marcelo R. Del Campo ◽  
Marco Gonzalez T ◽  
Hans Andresen ◽  
Freddy A. Cea
Keyword(s):  
Dairy Cows ◽  
Pregnancy Rate ◽  
Transition Period ◽  
Holstein Cows ◽  
Reproductive Efficiency ◽  
Control Group ◽  
Ovarian Activity ◽  
Uterine Infection ◽  
Uterine Involution ◽  
Downer Cow Syndrome

ABSTRACT Objective. Determine the effect of Glycoline® on reproductive efficiency in high producing dairy cows. Materials and methods. 100 Holstein cows one month before delivery were selected. About 21 days before parturition they were put in a barn and were randomized in two groups: Glycoline® Group (GG, n=50), 300 g/day of Glycoline® for 21 days antepartum and 250 g/day of GlycoLine® over the following 21 days postpartum, and the Control Group (CG, n=50) with the same feed and silage ration as GG during the same period, but without the addition of Glycoline®. Events and reproductive variables of the cows were recorded for 202 days. The data were systematized, analyzed and statistically compared. Results. Comparisons were made between GG and CG respectively: Retained placenta (0.0 vs. 12.0%; p=0.027), downer cow syndrome (14.3 vs. 44.0%; p=0.002), uterine involution (64.6 vs. 36.4%; p=0.019 ), uterine infection (10.4% vs. 35.5%; p=0.006), no ovarian activity (6.3 vs. 25.6%; p=0.018), follicular cysts (0.0 vs. 18.2%, p = 0.002), luteal structures (25.0 vs. 9.3% ; p=0.058), mean estrus presentation (40.1% vs. 63.5%; p=0.033) inseminated females (79.6 vs. 68.0%; p=0.017), pregnancy rate at day 150 (57.1 vs. 46.0%; p≥0.317 ) and intervals (days): calving to 1st estrus (39.8 vs. 63.2; p≤0.006), calving to IA (62.4 vs. 87.5; p≤0.006) calving to conception (81.7 vs. 93.6; p≤0.006; p=0.103). Conclusions. Results suggest that dietary Glycoline® added in the transition period improves reproductive efficiency of high-producing dairy cows. RESUMEN Objetivos. Determinar el efecto del Glycoline® sobre la eficiencia reproductiva en vacas lecheras de alta producción. Materiales y Métodos. Se seleccionaron 100 vacas Holstein un mes antes del parto. Alrededor de 21 días antes del parto se ubicaron en un establo y se asignaron al azar a dos Grupos: Grupo Glycoline® (GG; n=50), 300 g/día de Glycoline® durante 21 días preparto y 250 g/día de Glycoline® durante los siguientes 21 días posparto y Grupo Control (GC, n=50) la misma ración de concentrado y ensilaje que el GG durante el mismo período de tiempo, pero sin la adición de Glycoline®. Se registraron los eventos y las variables reproductivas de las vacas durante 202 días. Los datos fueron sistematizados, analizados y comparados estadísticamente. Resultados. Comparaciones entre el GG y GC respectivamente: Retención de placenta (0,0 vs 12.0%; p=0.027), síndrome de vaca caída (14.3 vs 44.0%; p=0.002), involución uterina (64.6 vs 36.4%; p=0.019), infección uterina (10.4% vs 35.5%; p=0.006), sin actividad ovárica (6.3 vs 25.6%; p=0.018), quistes foliculares (0.0 vs 18.2%, p=0.002), estructuras luteales (25.0 vs 9.3%; p=0.058), promedio presentación de celo (40.1% vs 63.5%; p=0.033), hembras inseminadas (79.6 vs 68.0%; p=0.017), tasa de preñez al día 150 (57.1 vs 46.0%; p≥0.317) y intervalos de tiempo (días): parto 1er -celo (39.8 vs 63.2; p≤0.006), parto-IA (62.4 vs 87.5; p≤0.006) y parto-preñez (81.7 vs 93.6; p≤0.006; p=0.103). Conclusiones. Los resultados sugieren que el Glycoline® adicionado en la dieta en el período de transición, mejora la eficiencia reproductiva de vacas de alta producción.

161 DIETARY ENERGY SOURCE IN PRIMIPAROUS DAIRY COWS DURING THE TRANSITION PERIOD: BLOOD METABOLITES AND FOLLICULAR CLASSIFICATION

2011 ◽  
Vol 23 (1) ◽  
pp. 183
Author(s):  
M. A. T. Artunduaga ◽  
S. G. Coelho ◽  
A. M. Borges ◽  
A. M. Q. Lana ◽  
H. M. Saturnino
Keyword(s):  
Fatty Acids ◽  
Dairy Cows ◽  
Propylene Glycol ◽  
Transition Period ◽  
Class I ◽  
Blood Metabolites ◽  
Control Group ◽  
Ovarian Activity ◽  
Class Iii ◽  
Calcium Salts

Solving reproductive problems of postpartum dairy cows has become one of the main targets of the scientific community even though the advances in this field are partial in most of the conducted research. There is a need to approach the problem with a multidisciplinary strategy that simultaneously includes nutritional and reproductive issues. Increasing the availability of glucogenic and lipogenic nutrients during the transition period has been hypothesised to improve energy balance and to decrease the incidence and severity of metabolic and reproductive disorders in early lactation. Based on the considerations mentioned above, the objective of this study was to compare the effects of a glucogenic or a lipogenic diet on blood metabolites and follicular dynamics in primiparous dairy cows during the transition period. Forty primiparous dairy cows received a lipogenic or glucogenic supplement during the transition period and were randomly assigned to 1 of 4 treatments [control; calcium salts of soybean fatty acids (CaS), Megalac-E; toasted soybean; and propylene glycol]. Diets were isocaloric and isoproteic. Blood samples were taken from each animal 10 and 5 days before the expected calving date and at days 7, 14, 21, 28, 35, and 42 postpartum. Ultrasound scanning was performed in all cows on Monday, Wednesday, and Friday up to day 45 postpartum. Follicles registered during ultrasound examination were classified in 4 categories: class I (3–5 mm), class II (6–9 mm), class III (10–15 mm), and class IV (>15 mm). Data analysis was performed using PROC GLM (SAS, 6.12, SAS Institute Inc., Cary, NC, USA, 1995). Metabolites and ovarian activity were analysed using a split-plot design. Pairwise comparisons of individual means were carried out using the Scott Knott and Duncan test. Values of P < 0.05 were considered statistically significant. Insulin and glucose concentrations were higher in the CaS group when compared with other treatments (P < 0.05). The lowest insulin and glucose concentrations were observed on cows supplemented with propylene glycol. Nonesterified fatty acid concentrations (NEFA) were lower for all treatments compared with the control group (P < 0.05). The most efficient follicular growth pattern during the postpartum period was observed in the CaS group, which was characterised by a reduction in the number of class I and II follicles and an increase in class III and IV throughout the trial. In general, smaller follicles go through recruitment and selection processes to bigger follicles and these follicles probably remain stable due to the fact that this particular follicular class represents a transitory phase in which there are always follicles going under the processes of selection and dominance. Overall, results suggest that calcium salts of soybean fatty acids reduced the dramatic metabolic and endocrine changes of primiparous dairy cows during transition period, which could be associated with better reproductive performance. This work was supported by the FAPEMIG (Grant CVZ 600/06).

12 EFFECT OF HUMAN CHORIONIC GONADOTROPIN (hCG) ADMINISTRATION ON DAY 2 OR DAY 5 AFTER OESTRUS ON PREGNANCY RATE IN HIGH-YIELDING DAIRY COWS

2015 ◽  
Vol 27 (1) ◽  
pp. 98 ◽  
Author(s):  
J. M. Sanchez ◽  
V. Maillo ◽  
L. Molina ◽  
C. C. Perez-Marin ◽  
P. Lonergan ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Pregnancy Rate ◽  
Body Condition Score ◽  
Significant Proportion ◽  
Prostaglandin F2α ◽  
Gonadotropin Releasing Hormone ◽  
Pregnancy Rates ◽  
Holstein Cows ◽  
Control Group ◽  
Releasing Hormone

In cattle, ~40% of embryonic loss occurs in the period from Day 8 to Day 16 of pregnancy. A significant proportion of embryo loss may be due to inadequate circulating progesterone (P4) concentrations. Low P4 concentrations have also been implicated as a causative factor in the low pregnancy rates (PR) observed in high-yielding dairy cows. Administration of hCG during the early luteal phase stimulates hypertrophy of the original corpus luteum (CL) and, depending on the day of administration, induces ovulation of the first-wave dominant follicle and formation of a functional accessory CL, which increases circulating P4 concentrations. The aim of this study was to examine whether administration of hCG on Day 2 or Day 5 after oestrus after timed AI (TAI) would lead to an increase in pregnancy rates in dairy cattle. Lactating Holstein cows (n = 194) from 12 commercial dairy herds in Southern Spain (37.8833° N, 4.7667° W) with an average milk production at 37.8 L/cow per day and typically with a PR to first AI of ~30% were randomly assigned based on their body condition score (2.65 ± 0.05; mean ± SEM), parity (2.60 ± 0.09), and days in milk (75.06 ± 0.63) to 1 of 3 treatments and administered a single intramuscular injection of 3000 IU of hCG (4 mL of Veterin Corion) either (1) on Day 2 = 36 h after TAI (n = 65; hCG2 group), (2) Day 5 = 108 h after TAI (n = 64; hCG5 group), or (3) 4 mL of saline on Day 2 = 36 h after TAI (n = 65; control group). Cows were synchronized using a 7-day Ovsynch TAI protocol that included a P4-releasing intravaginal device (PRID DELTA 1.55 g). First, gonadotropin-releasing hormone (Cystorelin 100 mg) treatment was administered at PRID insertion (Day 0) followed by 25 mg Dinoprost (prostaglandin F2α: Enzaprost T) on Day 7 at PRID withdrawal. Then, 56 h later, the second gonadotropin-releasing hormone (100 mg) treatment was administered and all cows were inseminated 16 h later. Pregnancy was diagnosed by ultrasonography 28 to 32 days after TAI. Logistic regression model and chi-squared test were used to analyse data. Pregnancy rate to AI was significantly higher in the hCG2 and hCG5 groups than in the control group (43.1 and 45.3%, v. 27.7%; P < 0.05). A treatment-by-parity interaction was observed; while pregnancy rate for primiparous cows was not affected by treatment, multiparous cows from the hCG2 group had greater pregnancies per AI than those in the control group (47.2% v. 21.1%, respectively; P < 0.05). In conclusion, these preliminary results suggest that hCG administration on Day 2 and 5 after oestrus increases PR at first postpartum AI in Holstein cows. In addition, hCG on Day 2 increases the fertility in multiparous cows.This study was funded by the Spanish Ministry of Science and Innovation (AGL2012–37510) and partially supported by Ceva Salud Animal S.A., Spain – synchronization protocol and DFV, Spain – hCG treatments.

scholarly journals Effect of Natural Chinese Herbal Supplements (TCMF4) on Lactation Performance and Serum Biomarkers in Peripartal Dairy Cows

2022 ◽  
Vol 8 ◽  
Author(s):  
Yizhe Cui ◽  
Zhuorui Shan ◽  
Lintong Hou ◽  
Qiuju Wang ◽  
Juan J. Loor ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Milk Production ◽  
Total Protein ◽  
Dose Group ◽  
Production Performance ◽  
High Dose Group ◽  
Holstein Cows ◽  
Control Group ◽  
High Dose ◽  
Lactation Performance

This study examined the effect of mixed medicinal herbs from China in the ground form on milk yield and various blood metabolites before and after parturition in Holstein cows. Crushed Agastache rugosus, Scutellaria barbata, Pericarpium citri reticulate, and Radix glycyrrhizae were used to develop TCMF4. Thirty-two Chinese Holstein cows were randomly divided into a control group or groups receiving 0.1, 0.3, or 0.5 kg TCMF4/cow/d from −7 through 21 d relative to parturition. Blood samples for serum isolation were collected at −7, −1, 1, 7, 14, and 21 d relative to parturition and used to measure glucose, β-hydroxybutyric acid (BHBA), total protein, albumin, globulin, and alkaline phosphatase. Milk production was recorded daily for the first 21 d postpartum, and composition was analyzed at 7, 14, and 21 d. Data were analyzed using a one-way analysis of variance (ANOVA) for multiple comparisons. The average milk production during the first 21-d postpartum was 28.7 ± 6.9, 27.2 ± 7.1, 31.2 ± 6.8, and 38.5 ± 6.1 kg/d for control group and groups receiving 0.1, 0.3, or 0.5 kg TCMF4. Thus, average daily milk production increased between 9 to 34% by supplementation with TCMF4 compared with the control group. Compared with the control group, in the middle dose group, milk concentrations of lactose and total protein decreased by 21 and 19%, respectively, at d 7 around parturition, while total solids increased by 23% at d 21 in the high-dose group. Furthermore, compared with the control group, serum BHBA decreased by 50 and 20% at d −1 and 21 around parturition in the high-dose group. Overall, TCMF4 supplementation improved dry matter intake (DMI) and milk production of dairy cows during the periparturient period without adverse effects on liver function, and plasma BHBA concentrations of dairy cows tended to decrease when dietary TCMF4 increased, which suggested that TCMF4 might be used as potential additives in dairy cows to improve production performance.

scholarly journals Effect of Pegbovigrastim on Hematological Profile of Simmental Dairy Cows during the Transition Period

Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 841 ◽  
Author(s):  
Francesca Trimboli ◽  
Valeria Maria Morittu ◽  
Antonio Di Loria ◽  
Andrea Minuti ◽  
Antonella Anna Spina ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Blood Cells ◽  
Transition Period ◽  
Lower Percentage ◽  
Control Group ◽  
Volume Distribution ◽  
Polymorphonuclear Cells ◽  
Distribution Width ◽  
Hematological Profile ◽  
First Time

Pegbovigrastim is a long-acting analog of recombinant bovine granulocyte colony-stimulating factor, that promotes and increases the count and functionality of polymorphonuclear cells in dairy cows. The present study aimed to explore, for the first time in Simmental cows, the clinical and hematological effect of pegbovigrastim during the transition period (TP). Cows were randomly assigned into two groups: treated group (PEG; n = 16) received pegbovigrastim at approximately 7 days before expected parturition and within 6 h after calving, and control group (CTR; n = 16) received saline solution. Blood samples were obtained at −7, 0, 1, 3, 7, 14, 21, and 30 days relative to calving. PEG group showed white blood cells (WBC) count consistently higher compared with CTR group (p < 0.001) until to 3 weeks after calving. Neutrophils remained higher in PEG group (p < 0.001) up to three weeks after calving, compared with CTR group, with slight increment of band cells. Moreover, PEG group displayed a lower index of myeloperoxidase at 1, 3, and 7 days after calving (p < 0.01) compared with CTR. Basophils and lymphocytes showed a similar trend to those observed for neutrophils at 1 day after calving in PEG group. Finally, monocytes remained markedly elevated until 3 days after calving in PEG compared to CTR group (p < 0.001), whereas in PEG group, eosinophils population showed lower percentage values at 1 and 3 days after calving but higher values at 30 days compared with CTR group. PEG group was characterized by lower red blood cells (RBCs) count compared with CTR group (p < 0.05) and higher % of red cell volume distribution width (RDW) from week 2 and mean corpuscular volume (MCV) at 30 days after calving. In addition, the mean platelet volume (MPV) was significantly higher in PEG group at calving, 1, 3, and 7 days after calving compared with CTR group (p < 0.05). For the first time, we described the effect of pegbovigrastim in a breed not specialized exclusively in milk production as Holstein, but with dual purpose (meat and milk), evaluating the complete hematological profile in cows during the transition period. These results provide evidence on the proliferative effect of pegbovigrastim on WBC in Simmental breed highlighting its possible side effect on RBCs.

scholarly journals Serum proteinogram and biochemistry of Holstein cows in the peripartum period

2019 ◽  
Vol 39 (5) ◽  
pp. 342-347
Author(s):  
Thaís G. Rocha ◽  
Camila Bortoletto ◽  
Daniela G. Silva ◽  
Kalina M.M.G. Simplício ◽  
Luiz F. Zafalon ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Dairy Cows ◽  
Total Protein ◽  
Repeated Measures ◽  
Transition Period ◽  
Serum Levels ◽  
Inorganic Phosphorus ◽  
Holstein Cows ◽  
Total Calcium ◽  
Peripartum Period

ABSTRACT: In face of the few reports found in national literature analyzing the potential influence of parturition number in serum proteinogram and biochemical profile in the peripartum period of high yielding dairy cows, the aim of the present study was to comparatively evaluate the dynamics of these serum constituents’ concentrations in blood samples obtained from primiparous and multiparous Holstein cows, 60 and 30 days prepartum and in the day of parturition. Data were analyzed by repeated measures variance analysis (ANOVA) and differences between groups and moments were analyzed by Tukey’s test. Results were considered significant when P<0.05. Parity influenced levels of total protein, albumin, globulins, magnesium, cholesterol, which were higher in multiparous cows, as well as concentrations of ceruloplasmin, total calcium, chloride and alkaline phosphatase activity, which were higher in primiparous cows. Parturition influenced serum concentrations of ceruloplasmin (+58%), transferrin (-25%), haptoglobin (+33%), total protein (-17%), globulins (-25%), immunoglobulin A (-43%), immunoglobulin G (-24%), total calcium (-12%), inorganic phosphorus (-10%), chloride (+5%), sodium (+4%), cholesterol (-23%), triglycerides (-38.6%), as well as activities of aspartate aminotransferase (+14%) and alkaline phosphatase (+28%). A decrease in serum levels of total calcium, inorganic phosphorus, cholesterol and triglycerides was more pronounced in multiparous than in primiparous cows. These results demonstrate that the interpretation of proteinogram and serum constituents should take into consideration lactation number and the moment of parturition as relevant factors in high yielding dairy cows in the transition period.

Factors in the resumption of ovarian activity and uterine involution in postpartum dairy cows

1995 ◽  
Vol 38 (3) ◽  
pp. 203-214 ◽  
Author(s):  
A El-Din. Zain ◽  
T Nakao ◽  
M Abdel Raouf ◽  
M Moriyoshi ◽  
K Kawata ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Ovarian Activity ◽  
Uterine Involution

Effects of calving-related disorders on prostaglandin, calcium, ovarian activity and uterine involution in postrartum dairy cows

1994 ◽  
Vol 42 (1) ◽  
pp. 183-203 ◽  
Author(s):  
C.A. Risco ◽  
M. Drost ◽  
W.W. Thatcher ◽  
J. Savio ◽  
M.J. Thatcher
Keyword(s):  
Dairy Cows ◽  
Ovarian Activity ◽  
Uterine Involution

scholarly journals Risk Assessment and Consequences of Retained Placenta for Uterine Health, Reproduction and Milk Yield in Dairy Cows

2009 ◽  
Vol 78 (1) ◽  
pp. 163-172 ◽  
Author(s):  
László Könyves ◽  
Ottó Szenci ◽  
Viktor Jurkovich ◽  
Lászlóné Tegzes ◽  
Attila Tirián ◽  
...  
Keyword(s):  
Dairy Cows ◽  
Milk Production ◽  
Ovarian Activity ◽  
Nefa Concentration ◽  
Acid Base ◽  
Retained Placenta ◽  
Uterine Involution ◽  
Holstein Friesian ◽  
Uterine Health ◽  
Plasma Nefa Concentration

The objective of the study was to determine the value of metabolic indicators characterising the energy and acid-base metabolism of dairy cows for predicting the risk of retained placenta (RP). The connection between RP and different factors analysed, and the effect of RP on the development of puerperal metritis (PM) as well as on reproduction and milk production was studied. A total of 105 Holstein-Friesian cows were included and sampled between days -14–0 prepartum and then on days 4, 10–14, 28–35, 56–63 and 84–91 postpartum, for metabolic tests. From day 4, at times coinciding with the days of metabolic sampling, uterine involution and metritis were monitored by clinical examination, and from days 28–35 ovarian activity was monitored by ultrasonography. On days -14–0, the plasma non-esterified fatty acids (NEFA) concentration showed a positive Odds Ratio (OR) 102.1, P < 0.05; while urinary net acid-base excretion (NABE) exhibited a negative correlation (OR 0.99; P < 0.05) with the odds of RP. NEFA and NABE were negatively correlated (Pearson’s coefficient: -0.24; P < 0.05). Ketonuria of grade ≥ 2+ increased the probability of RP (OR: Infinite; P < 0.05). On day -14–0 prepartum, elevated plasma NEFA concentration, decreasing urinary NABE and grade ≥ 2+ ketonuria indicates a higher risk of RP. The odds of RP were not influenced by parity, sex and viability of the calf, and the calving assistance. RP increased the risk of PM (OR: 27.3; P < 0.0001). The RP alone did not exert an influence on the metabolic status, reproductive performance or milk production of cows.

scholarly journals The puerperium in dairy cows: ovarian activity, uterine involution and follicular dynamics

2015 ◽  
Vol 13 ◽  
Author(s):  
José Carlos Dos Santos Breda ◽  
Luiz Ernandes Kozicki
Keyword(s):  
Dairy Cows ◽  
Reproductive Performance ◽  
Postpartum Period ◽  
Reproductive Tract ◽  
Ovarian Activity ◽  
Non Invasive ◽  
The Past ◽  
Uterine Involution ◽  
Follicular Dynamics

The study of ovarian follicular dynamics (OFD) and other changes in the bovine reproductive tract has developedsignificantly over the past two decades, primarily due to the use of non-invasive investigative approaches suchas ultrasound. Advances in ultrasound examinations have provided a better understanding of ovarian activity,uterine involution, oviducts status, and other segments of the reproductive tract in the bovine postpartumperiod. Procedures including tracking of the reproductive tract have likewise aided in the development of newmethodologies and techniques to improve reproductive performance in cattle. The aim of this review was tosummarize knowledge regarding the reproductive tract in dairy cows during the postpartum period.

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