scholarly journals Heartland virus: a novel and emerging tick-borne encephalitis

2016 ◽  
pp. 5099-5101
Author(s):  
Salim Mattar V. ◽  
Marco González T.
Keyword(s):  
United States ◽  
Causative Agent ◽  
Human Disease ◽  
Fatal Case ◽  
The United States ◽  
Tick Borne Encephalitis

Heartland virus (HRTV) is a Bunyaviridae, phlebovirus that it has recently emerged as the causative agent of human disease characterized by thrombocytopenia and leukopenia in the United States and China. It seems to be the HRTV has been also reported in China, Japan and Korea. Recently the first fatal case of HRTV disease in an 80-year-old Tennessee resident was reported (1)

scholarly journals Human Coinfection withBorrelia burgdorferiandBabesia microtiin the United States

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Kristen L. Knapp ◽  
Nancy A. Rice
Keyword(s):  
United States ◽  
Lyme Disease ◽  
Causative Agent ◽  
Ixodes Scapularis ◽  
Immunological Response ◽  
The United States ◽  
Babesia Microti ◽  
Current State ◽  
Tick Borne Disease ◽  
Multiple Pathogens

Borrelia burgdorferi, the causative agent of Lyme disease, andBabesia microti, a causative agent of babesiosis, are increasingly implicated in the growing tick-borne disease burden in the northeastern United States. These pathogens are transmitted via the bite of an infected tick vector,Ixodes scapularis, which is capable of harboring and inoculating a host with multiple pathogens simultaneously. Clinical presentation of the diseases is heterogeneous and ranges from mild flu-like symptoms to near-fatal cardiac arrhythmias. While the reason for the variability is not known, the possibility exists that concomitant infection with bothB. burgdorferiandB. microtimay synergistically increase disease severity. In an effort to clarify the current state of understanding regarding coinfection withB. burgdorferiandB. microti, in this review, we discuss the geographical distribution and pathogenesis of Lyme disease and babesiosis in the United States, the immunological response of humans toB. burgdorferiorB. microtiinfection, the existing knowledge regarding coinfection disease pathology, and critical factors that have led to ambiguity in the literature regarding coinfection, in order to eliminate confusion in future experimental design and investigation.

scholarly journals Carios kelleyi (Acari: Ixodida: Argasidae) Infected With Rickettsial Agents Documented Infesting Housing in Kansas, United States

2021 ◽  
Author(s):  
Robyn M Nadolny ◽  
Ashley C Kennedy ◽  
James M Rodgers ◽  
Zachary T Vincent ◽  
Hannah Cornman ◽  
...  
Keyword(s):  
Public Health ◽  
United States ◽  
Health Center ◽  
Human Disease ◽  
Multilocus Sequence Typing ◽  
The United States ◽  
Rickettsia Species ◽  
History Of ◽  
Tick Borne Disease ◽  
Blood Meals

Abstract During September–December 2018, 25 live ticks were collected on-post at Fort Leavenworth, Kansas, in a home with a history of bat occupancy. Nine ticks were sent to the Army Public Health Center Tick-Borne Disease Laboratory and were identified as Carios kelleyi (Cooley and Kohls, 1941), a species that seldom bites humans but that may search for other sources of blood meals, including humans, when bats are removed from human dwellings. The ticks were tested for numerous agents of human disease. Rickettsia lusitaniae was identified by multilocus sequence typing to be present in two ticks, marking the first detection of this Rickettsia agent in the United States and in this species of tick. Two other Rickettsia spp. were also detected, including an endosymbiont previously associated with C. kelleyi and a possible novel Rickettsia species. The potential roles of C. kelleyi and bats in peridomestic Rickettsia transmission cycles warrant further investigation.

scholarly journals A Fatal Case of Primary Amoebic Meningoencephalitis from Recreational Waters

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Edward Hamaty ◽  
Saif Faiek ◽  
Minesh Nandi ◽  
David Stidd ◽  
Manish Trivedi ◽  
...  
Keyword(s):  
United States ◽  
Mortality Rate ◽  
Bacterial Meningitis ◽  
Fatal Case ◽  
Altered Mental Status ◽  
The United States ◽  
Recreational Waters ◽  
Primary Amoebic Meningoencephalitis ◽  
Presenting Symptoms ◽  
Amoebic Meningoencephalitis

Background. Naegleria Fowleri is a single-cell, thermophilic amphizoid amoeba, and a rare known causative agent for primary amoebic meningoencephalitis with >97% mortality rate. The amoeba resides in freshwater lakes and ponds but can also survive in inadequately chlorinated pools and recreational waters. The mode of infection includes activities such as diving or jumping into freshwater or submerging the head under the water. Although most commonly seen in the southern United States, it is essential to keep this clinical suspicion in mind regardless of geography, as presenting symptoms can be very similar to classic bacterial meningitis. Case Summary. We report the first-ever case in the state of New Jersey of a 29-year-old male presented after a visit to a recreational water park in Texas five days before his presentation with altered mental status. In ICU, his ICP remained refractory to multiple therapies, including antibiotics and antivirals, external ventriculostomy drain, hypertonic saline, pentobarbital-induced coma, and bilateral hemicraniectomies. The CSF analysis revealed trophozoites indicating a protozoan infection, which we diagnosed in the neurocritical unit, and the patient was then immediately started with treatment that included amphotericin B, rifampin, azithromycin, and fluconazole. This suspicion was promptly confirmed by the Center for Disease Control (CDC). Unfortunately, despite all the aggressive intervention by the multidisciplinary team, the patient did not survive. Conclusion. As per the CDC, only four people out of 143 known infected individuals in the United States from 1962 to 2017 have survived. Symptoms start with a median of 5 days after exposure to contaminated water. Given the rarity of this case and its very high mortality rate, it is crucial to diagnose primary amoebic meningoencephalitis accurately as its presentation can mimic bacterial meningitis. It is vital to obtain a careful and thorough history, as it can aid in prompt diagnosis and treatment.

Listeria Prevalence and Listeria monocytogenes Serovar Diversity at Cull Cow and Bull Processing Plants in the United States†

2007 ◽  
Vol 70 (11) ◽  
pp. 2578-2582 ◽  
Author(s):  
MICHAEL N. GUERINI ◽  
DAYNA M. BRICHTA-HARHAY ◽  
STEVEN D. SHACKELFORD ◽  
TERRANCE M. ARTHUR ◽  
JOSEPH M. BOSILEVAC ◽  
...  
Keyword(s):  
United States ◽  
Listeria Monocytogenes ◽  
Causative Agent ◽  
Warm Season ◽  
The United States ◽  
Prevalence Data ◽  
Beef Processing ◽  
Processing Plants ◽  
Many Sources ◽  
Cull Cow

Listeria monocytogenes, the causative agent of epidemic and sporadic listeriosis, is routinely isolated from many sources, including cattle, yet information on the prevalence of Listeria in beef processing plants in the United States is minimal. From July 2005 through April 2006, four commercial cow and bull processing plants were sampled in the United States to determine the prevalence of Listeria and the serovar diversity of L. monocytogenes. Samples were collected during the summer, fall, winter, and spring. Listeria prevalence on hides was consistently higher during cooler weather (28 to 92% of samples) than during warmer weather (6 and 77% of samples). The Listeria prevalence data collected from preevisceration carcass ranged from undetectable in some warm season samples to as high as 71% during cooler weather. Listeria on postintervention carcasses in the chill cooler was normally undetectable, with the exception of summer and spring samples from one plant where >19% of the carcasses were positive for Listeria. On hides, L. monocytogenes serovar 1/2a was the predominant serovar observed, with serovars 1/2b and 4b present 2.5 times less often and serovar 1/2c not detected on any hides sampled. L. monocytogenes serovars 1/2a, 1/2c, and 4b were found on postintervention carcasses. This prevalence study demonstrates that Listeria species are more prevalent on hides during the winter and spring and that interventions being used in cow and bull processing plants appear to be effective in reducing or eliminating Listeria contamination on carcasses.

A Fatal Case of Toxic-Shock Syndrome following Cholecystectomy

1984 ◽  
Vol 24 (4) ◽  
pp. 269-270
Author(s):  
S. Beck ◽  
P.A. Fenton ◽  
P. D. Rollinson
Keyword(s):  
United States ◽  
Toxic Shock Syndrome ◽  
Fatal Case ◽  
The United States ◽  
Case Definition ◽  
Toxic Shock ◽  
The United Kingdom ◽  
Surgical Wounds ◽  
Focus Of Infection ◽  
Menstruating Women

Toxic-shock syndrome is less common in the United Kingdom than in the United States, and in both countries the majority of cases have been diagnosed in menstruating women (de Saxe et al., 1982). Reingold et al. (1982) reviewed 130 cases of non-menstrual related toxic-shock syndrome in the United States. They detailed specific criteria for case definition and quoted a fatality rate of 9.2 per cent. Only 17 of these cases were associated with infected surgical wounds and none followed cholecystectomy. The onset of symptoms was one to 64 days post-operatively (median two days), and in all but one of these cases the signs of wound infection were minimal. We describe a fatal case of toxic-shock syndrome which occurred in an elderly man 25 days after cholecystectomy where the focus of infection was a wound sinus.

scholarly journals A new causative agent of epidemic cerebrospinal meningitis. As reported by the Bureau of the Public Health Service

2021 ◽  
Vol 32 (1) ◽  
pp. 91-91
Author(s):  
Z. B.
Keyword(s):  
Public Health ◽  
United States ◽  
Health Service ◽  
Causative Agent ◽  
Public Health Service ◽  
The United States ◽  
The Public ◽  
The Past ◽  
Very High

According to the Bureau of the Public Health Service (Washington), over the past five years, the number of diseases in the United States has been epidemic. cerebrospin. meningitis was very high (numbers not indicated), exceeding the number of diseases in the period since the beginning of the worlds, war.

scholarly journals Ischaemic events and myopericarditis after smallpox vaccination

2003 ◽  
Vol 7 (15) ◽  
Author(s):  
C Auckland
Keyword(s):  
United States ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Vaccination Programme ◽  
Fatal Case ◽  
The United States ◽  
Smallpox Vaccination ◽  
The Military

Fourteen cases of acute myopericarditis and one fatal case of acute myocardial infarction among approximately 350 000 primary smallpox vaccinees have been reported in the military vaccination programme in the United States. Four cases of myopericarditis and 6 acute ischaemic episodes, including 2 deaths following acute myocardial infarction, have also been reported from the civilian smallpox vaccination programme (among 29 600 vaccinees) (1, 2).

scholarly journals La Crosse Virus Disease in the United States, 2003–2019

2021 ◽  
Author(s):  
Grace M. Vahey ◽  
Nicole P. Lindsey ◽  
J. Erin Staples ◽  
Susan L. Hills
Keyword(s):  
United States ◽  
Human Disease ◽  
Virus Disease ◽  
Disease Incidence ◽  
Case Fatality ◽  
Febrile Illness ◽  
The United States ◽  
Surveillance Data ◽  
La Crosse Virus ◽  
Neuroinvasive Disease

La Crosse virus (LACV) is an arthropod-borne virus that can cause a nonspecific febrile illness, meningitis, or encephalitis. We reviewed U.S. LACV surveillance data for 2003–2019, including human disease cases and nonhuman infections. Overall, 318 counties in 27 states, principally in the Great Lakes, mid-Atlantic, and southeastern regions, reported LACV activity. A total of 1,281 human LACV disease cases were reported, including 1,183 (92%) neuroinvasive disease cases. The median age of cases was 8 years (range: 1 month–95 years); 1,130 (88%) were aged < 18 years, and 754 (59%) were male. The most common clinical syndromes were encephalitis (N = 960; 75%) and meningitis (N = 219, 17%). The case fatality rate was 1% (N = 15). A median of 74 cases (range: 35–130) was reported per year. The average annual national incidence of neuroinvasive disease cases was 0.02 per 100,000 persons. West Virginia, North Carolina, Tennessee, and Ohio had the highest average annual state incidences (0.16–0.61 per 100,000), accounting for 80% (N = 1,030) of cases. No animal LACV infections were reported. Nine states reported LACV-positive mosquito pools, including three states with no reported human disease cases. La Crosse virus is the most common cause of pediatric neuroinvasive arboviral disease in the United States. However, surveillance data likely underestimate LACV disease incidence. Healthcare providers should consider LACV disease in patients, especially children, with febrile illness, meningitis, or encephalitis in areas where the virus circulates and advise their patients on ways to prevent mosquito bites.

scholarly journals Role of air temperature and humidity in the transmission of SARS-CoV-2 in the United States

2020 ◽  
Author(s):  
Yiqun Ma ◽  
Sen Pei ◽  
Jeffrey Shaman ◽  
Robert Dubrow ◽  
Kai Chen
Keyword(s):  
United States ◽  
Air Temperature ◽  
Causative Agent ◽  
Reproduction Number ◽  
The United States ◽  
Meteorological Conditions ◽  
Specific Humidity ◽  
Lower Temperature ◽  
The Relationship

AbstractImproved understanding of the effects of meteorological conditions on the transmission of SARS-CoV-2, the causative agent for COVID-19 disease, is urgently needed to inform mitigation efforts. Here, we estimated the relationship between air temperature or specific humidity (SH) and SARS-CoV-2 transmission in 913 U.S. counties with abundant reported infections from March 15 to August 31, 2020. Specifically, we quantified the associations of daily mean temperature and SH with daily estimates of the SARS-CoV-2 reproduction number (Rt) and calculated the fraction of Rt attributable to these meteorological conditions. Both lower temperature and lower SH were significantly associated with increased Rt. The fraction of Rt attributable to temperature was 5.10% (95% eCI: 5.00 - 5.18%), and the fraction of Rt attributable to SH was 14.47% (95% eCI: 14.37 - 14.54%). These fractions generally were higher in northern counties than in southern counties. Our findings indicate that cold and dry weather are moderately associated with increased SARS-CoV-2 transmissibility, with humidity playing a larger role than temperature.

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