scholarly journals Revisiting Peripartum Cardiomyopathy: A Subsequent Pregnancy

2018 ◽  
Vol 2018 ◽  
Author(s):  
Amanda Krauss, MS-IV ◽  
◽  
Barker, MD Barker, MD ◽  
Kaitlin McGrogan, DO ◽  
Adam Franks, MD ◽  
...  
Keyword(s):  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy

Abstract 17220: Risk Factors for Recurrent Peripartum Cardiomyopathy in 783 Women in California

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_1) ◽  
Author(s):  
Punag Divanji ◽  
Gregory Nah ◽  
Ian Harris ◽  
Anu Agarwal ◽  
Nisha I Parikh
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Logistic Regression ◽  
Regression Models ◽  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy ◽  
Lv Function ◽  
Logistic Regression Models ◽  
Grand Multiparity ◽  
Adjusted Logistic Regression

Introduction: Characterized by significant left ventricular (LV) dysfunction and clinical heart failure (HF), peripartum cardiomyopathy (PPCM) has an incidence of approximately 1/2200 live births (0.04%). Prior studies estimate that approximately 25% of those with recovered LV function will have recurrent clinical PPCM during subsequent pregnancies, compared to 50% of those without recovered LV function. Specific predictors of recurrent PPCM have not been studied in cohorts with large numbers. Methods: From 2005-2011, we identified 1,872,227 pregnancies by International Classification of Diseases, 9th Revision (ICD-9) codes in the California Healthcare Cost and Utilization Project (HCUP) database, which captures over 95% of the California hospitalized population. Excluding 15,765 women with prior cardiovascular disease (myocardial infarction, coronary artery disease, stroke, HF, valve disease, or congenital heart disease), yielded n=1,856,462 women. Among women without prior cardiovascular disease, we identified index and subsequent pregnancies with PPCM to determine episodes of recurrent PPCM. We considered the following potential predictors of PPCM recurrence in both univariate and age-adjusted logistic regression models: age, race, hypertension, diabetes, smoking, obesity, chronic kidney disease, family history, pre-eclampsia, ectopic pregnancy, income, and insurance status. Results: In HCUP, n=783 women had pregnancies complicated by PPCM (mean age=30.8 years). Among these women, n=133 had a subsequent pregnancy (17%; mean age=28.1 years), with a mean follow-up of 4.34 years (±1.71 years). In this group of 133 subsequent pregnancies, n=14 (10.5%) were complicated by recurrent PPCM, with a mean time-to-event of 2.2 years (±1.89 years). Among the risk factors studied, the only univariate predictor of recurrent PPCM was grand multiparity, defined as ≥ 5 previous deliveries (odds ratio: 22; 95% confidence interval 4.43-118.22). The other predictors we studied were not significantly associated with recurrent PPCM in either univariate or multivariable models. Conclusion: In a large population database in California with 783 cases of PPCM over a 6-year period, 17% of women had a subsequent pregnancy, of which 10.5% had recurrent PPCM. In age-adjusted logistic regression models, grand multiparity was the only statistically significant predictor of recurrent PPCM.

scholarly journals Subsequent Pregnancy in Peripartum Cardiomyopathy- Is the Answer Always No?

2019 ◽  
Vol 25 (8) ◽  
pp. S96
Author(s):  
Joyce Nyaucha Njoroge ◽  
Ike S. Okwuosa ◽  
Marla A. Mendelson
Keyword(s):  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy

scholarly journals Risk of subsequent pregnancy in previous peripartum cardiomyopathy – Clinical and echocardiograhic profile.

2018 ◽  
Vol 70 ◽  
pp. S48
Author(s):  
Ravindran R ◽  
Justin Paul G ◽  
Anne Princy S ◽  
Cecilly Mary Majella J
Keyword(s):  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy

scholarly journals Maternal and fetal prognosis of subsequent pregnancy in black African women with peripartum cardiomyopathy

2019 ◽  
Vol 11 (1) ◽  
pp. 41
Author(s):  
N. Yameogo ◽  
A.K. Samadoulougou ◽  
L.J. Kagambèga ◽  
K.J. Kologo ◽  
G. Millogo ◽  
...  
Keyword(s):  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy ◽  
African Women ◽  
Black African

Outcome of subsequent pregnancy in patients with documented peripartum cardiomyopathy

2004 ◽  
Vol 93 (11) ◽  
pp. 1441-1443 ◽  
Author(s):  
Karen Sliwa ◽  
Olaf Forster ◽  
Fitzgerald Zhanje ◽  
Geoff Candy ◽  
John Kachope ◽  
...  
Keyword(s):  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy

Imaging-Based Risk Stratification for Recurrence Risk in Women with a History of Peripartum Cardiomyopathy

2021 ◽  
Author(s):  
Marwan Ma'ayeh ◽  
Jeremy A. Slivnick ◽  
Monique E. McKiever ◽  
Zachary D. Garrett ◽  
Woobeen Lim ◽  
...  
Keyword(s):  
Global Longitudinal Strain ◽  
Recurrence Risk ◽  
Left Ventricular ◽  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Risk Of Recurrence ◽  
Key Points ◽  
History Of

Objective Peripartum cardiomyopathy (PPCM) affects 1:1,000 U.S. pregnancies, and while many recover from the disease, the risk of recurrence in subsequent pregnancy (SSP) is high. This study aims to evaluate the utility of left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) to predict the risk of recurrence of PPCM in SSP. Study Design We retrospectively evaluated outcomes in women with a history of PPCM and SSP at a large-volume cardioobstetrics program (2008–2019). Results There were 18 women who had incident PPCM and pursued SSP. Of 24 pregnancies in these women, 8 (33%) were complicated by the development of recurrent PPCM. LVEF ≥ 52% or GLS ≤ −16 was associated with a low risk of recurrent PPCM. Conclusion Approximately one-third of women with PPCM developed recurrent PPCM in SSP. LVEF and GLS on prepregnancy echocardiography may predict the risk of recurrence. Additional studies evaluating risk for recurrence are required to better understand which women are the safest to consider SSP. Key Points

Pregnancy and subsequent pregnancy outcomes in peripartum cardiomyopathy

2010 ◽  
Vol 37 (3) ◽  
pp. 222-227 ◽  
Author(s):  
Debasmita Mandal ◽  
Saroj Mandal ◽  
Dipankar Mukherjee ◽  
Subhash Chandra Biswas ◽  
Tapan Kumar Maiti ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Subsequent Pregnancy ◽  
Peripartum Cardiomyopathy
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