scholarly journals Limited Value of Urinary Cotinine to Creatinine Ratio as an Indicator for Tobacco Smoke Exposure

1992 ◽  
Vol 2 (2) ◽  
pp. 91-95
Author(s):  
Masahiro Kihara ◽  
Masako Kihara ◽  
Naoyuki Okamoto ◽  
Eigo Higashi ◽  
Shigeru Matsukura ◽  
...  
Keyword(s):  
Tobacco Smoke ◽  
Smoke Exposure ◽  
Tobacco Smoke Exposure ◽  
Creatinine Ratio ◽  
Urinary Cotinine

Assessment of tobacco smoke exposure in Hong Kong preschool children: questionnaire or urinary cotinine?

2012 ◽  
Vol 13 ◽  
pp. S67-S68
Author(s):  
T.F. Leung ◽  
I.H.S. Chan ◽  
T.C. Liu ◽  
W.C. Chan ◽  
H.Y. Sy ◽  
...  
Keyword(s):  
Hong Kong ◽  
Preschool Children ◽  
Tobacco Smoke ◽  
Smoke Exposure ◽  
Tobacco Smoke Exposure ◽  
Urinary Cotinine

scholarly journals URINARY COTININE AS A MEASURE OF TOBACCO SMOKE EXPOSURE IN UTERO AND INFANCY

1984 ◽  
Vol 18 ◽  
pp. 229A-229A
Author(s):  
R Etzel ◽  
R Greenberg ◽  
N Haley ◽  
F Loda
Keyword(s):  
Tobacco Smoke ◽  
In Utero ◽  
Smoke Exposure ◽  
Tobacco Smoke Exposure ◽  
Urinary Cotinine

scholarly journals Assessing secondhand and thirdhand tobacco smoke exposure in Canadian infants using questionnaires, biomarkers, and machine learning

2021 ◽  
Author(s):  
Jaclyn Parks ◽  
Kathleen E. McLean ◽  
Lawrence McCandless ◽  
Russell J. de Souza ◽  
Jeffrey R. Brook ◽  
...  
Keyword(s):  
Machine Learning ◽  
Tobacco Smoke ◽  
Smoke Exposure ◽  
Tobacco Smoke Exposure ◽  
Linear Regression Models ◽  
Thirdhand Smoke ◽  
Urinary Cotinine ◽  
Smoking Exposure ◽  
Shs Exposure ◽  
Technological Improvements

Abstract Background As smoking prevalence has decreased in Canada, particularly during pregnancy and around children, and technological improvements have lowered detection limits, the use of traditional tobacco smoke biomarkers in infant populations requires re-evaluation. Objective We evaluated concentrations of urinary nicotine biomarkers, cotinine and trans-3’-hydroxycotinine (3HC), and questionnaire responses. We used machine learning and prediction modeling to understand sources of tobacco smoke exposure for infants from the CHILD Cohort Study. Methods Multivariable linear regression models, chosen through a combination of conceptual and data-driven strategies including random forest regression, assessed the ability of questionnaires to predict variation in urinary cotinine and 3HC concentrations of 2017 3-month-old infants. Results Although only 2% of mothers reported smoking prior to and throughout their pregnancy, cotinine and 3HC were detected in 76 and 89% of the infants’ urine (n = 2017). Questionnaire-based models explained 31 and 41% of the variance in cotinine and 3HC levels, respectively. Observed concentrations suggest 0.25 and 0.50 ng/mL as cut-points in cotinine and 3HC to characterize SHS exposure. This cut-point suggests that 23.5% of infants had moderate or regular smoke exposure. Significance Though most people make efforts to reduce exposure to their infants, parents do not appear to consider the pervasiveness and persistence of secondhand and thirdhand smoke. More than half of the variation in urinary cotinine and 3HC in infants could not be predicted with modeling. The pervasiveness of thirdhand smoke, the potential for dermal and oral routes of nicotine exposure, along with changes in public perceptions of smoking exposure and risk warrant further exploration.

A monoclonal antibody-based enzyme-linked immunosorbent assay for human urinary cotinine to monitor tobacco smoke exposure

2011 ◽  
Vol 3 (9) ◽  
pp. 1995 ◽  
Author(s):  
Norihiro Kobayashi ◽  
Erika Banzono ◽  
Yuko Shimoda ◽  
Hiroyuki Oyama ◽  
Toshiomi Kunihiro ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Immunosorbent Assay ◽  
Tobacco Smoke ◽  
Smoke Exposure ◽  
Tobacco Smoke Exposure ◽  
Enzyme Linked Immunosorbent Assay ◽  
Urinary Cotinine

A Validated Method for Urinary Cotinine Quantification Used to Classify Active and Environmental Tobacco Smoke Exposure

2013 ◽  
Vol 9 (3) ◽  
pp. 447-456 ◽  
Author(s):  
Silvia Fustinoni ◽  
Laura Campo ◽  
Elisa Polledri ◽  
Rosa Mercadante ◽  
Laura Erspamer ◽  
...  
Keyword(s):  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Environmental Tobacco Smoke Exposure ◽  
Smoke Exposure ◽  
Tobacco Smoke Exposure ◽  
Urinary Cotinine
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