scholarly journals Therapeutic Efficacy Evaluation of Pegylated Liposome Encapsulated With Vinorelbine Plus 111In Repeated Treatments in Human Colorectal Carcinoma With Multimodalities of Molecular Imaging

2019 ◽  
Vol 17 (1) ◽  
pp. 61-76
Author(s):  
YI-CHUN CHIEN ◽  
YING-HSIANG CHOU ◽  
WEI-HSUN WANG ◽  
JOHN CHUN-HAO CHEN ◽  
WEN-SHIN CHANG ◽  
...  
2018 ◽  
Vol 46 ◽  
pp. 7-13 ◽  
Author(s):  
Hibah M. Aldawsari ◽  
Mahmoud A. Elfaky ◽  
Usama A. Fahmy ◽  
Bader M. Aljaeid ◽  
Ohood A. Alshareef ◽  
...  

2020 ◽  
Vol 16 (9) ◽  
pp. 1273-1280
Author(s):  
Giuseppina Tommonaro ◽  
Ali M. El-Hagrassi ◽  
Walid Fayad ◽  
Carmine Iodice ◽  
Kamel H. Shaker ◽  
...  

Background: Colorectal cancer represents one of the prominent causes of mortality worldwide in men and women. The objective of this study was to search for new potential anticancer compounds, both in prevention and treatment of colorectal cancer. The anticancer potential of marine bacterial extracts against Human colorectal carcinoma cell line (HCT116) was evaluated as well as the partial identification of bioactive metabolites. Methods: All bacterial extracts were tested for their cytotoxicity against HCT116 cell line by means of MTT assay. The highly cytotoxic dichloromethane extracts of marine sponge-associated bacteria Vibrio sp. and Bacillus sp. were analyzed by GC-MS. Results: Two fractions, Vib3 and Bac3, exhibited a very interesting cytotoxicity against human colorectal carcinoma (HCT116) cell line, with a percentage of cytotoxicity of 96.04 % and 29.48 %, respectively. Discussion: The GC-MS analysis revealed the presence of two major fatty acids, palmitic and oleic acids, in Vib3 fraction and fatty acid esters and phenolic compounds in Bac3 fraction. Conclusion: Based on previous literature, it may be hypothesized that the anticancer activity of bacterial extracts could be, at least partially, to the fatty acids fraction.


2021 ◽  
Vol 15 (1) ◽  
pp. 55-67
Author(s):  
Se Hee Park ◽  
Kon-Young Ji ◽  
Hyun Min Kim ◽  
Sang Hoon Ma ◽  
Seo Young Park ◽  
...  

1988 ◽  
Vol 57 (3) ◽  
pp. 277-280 ◽  
Author(s):  
R Giavazzi ◽  
A Garofalo ◽  
G Damia ◽  
S Garattini ◽  
M D'Incalci

1997 ◽  
Vol 25 (2) ◽  
pp. 264S-264S ◽  
Author(s):  
ROBERT BREW ◽  
JOHN S. ERIKSON ◽  
DAVID C. WEST ◽  
BRIAN F. FLANAGAN ◽  
STEPHEN E. CHRISTMAS

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