Patient Age and Long-term Survival in Colorectal Cancer Patients Who Undergo Emergency Surgery

2021 ◽  
Vol 41 (2) ◽  
pp. 1069-1076
Author(s):  
KEISUKE KOSUMI ◽  
KOSUKE MIMA ◽  
ATSUSHI MORITO ◽  
SHINSEI YUMOTO ◽  
TAKASHI MATSUMOTO ◽  
...  
2012 ◽  
Vol 14 (12) ◽  
pp. 896-904 ◽  
Author(s):  
Zuli Yang ◽  
Liang Kang ◽  
Lei Wang ◽  
Jun Xiang ◽  
Guanfu Cai ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 2410
Author(s):  
Chungyeop Lee ◽  
In-Ja Park ◽  
Kyung-Won Kim ◽  
Yongbin Shin ◽  
Seok-Byung Lim ◽  
...  

The effect of perioperative sarcopenic changes on prognosis remains unclear. We conducted a retrospective cohort study with 2333 non-metastatic colorectal cancer patients treated between January 2009 and December 2012 at the Asan Medical Center. The body composition at diagnosis was measured via abdominopelvic computed tomography (CT) using Asan-J software. Patients underwent CT scans preoperatively, as well as at 6 months–1 year and 2–3 years postoperatively. The primary outcome was the association between perioperative sarcopenic changes and survival. According to sarcopenic criteria, 1155 (49.5%), 890 (38.2%), and 893 (38.3%) patients had sarcopenia preoperatively, 6 months–1 year, and 2–3 years postoperatively, respectively. The 5-year overall survival (OS) (95.8% vs. 92.1%, hazard ratio (HR) = 2.234, p < 0.001) and 5-year recurrence-free survival (RFS) (93.2% vs. 86.2%, HR = 2.251, p < 0.001) rates were significantly lower in patients with preoperative sarcopenia. Both OS and RFS were lower in patients with persistent sarcopenia 2–3 years postoperatively than in those who recovered (OS: 96.2% vs. 90.2%, p = 0.001; RFS: 91.1% vs. 83.9%, p = 0.002). In multivariate analysis, postoperative sarcopenia was confirmed as an independent factor associated with decreased OS and RFS. Pre- and postoperative sarcopenia and changes in the condition during surveillance were associated with oncological outcomes.


Gerodontology ◽  
1993 ◽  
Vol 10 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Per-Olof J. Glantz ◽  
Krister Niler

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